Did You Know...
...that while attempting to develop a super strong glue, 3M employee Spencer Silver accidentally developed a glue that was so weak it would barely hold two pieces of paper together? However, his colleague Art Fry needed the glue. Fry sang with his church choir and marked the pages of his hymnal with small scraps of paper that often fell out. He used Silver's glue to hold the papers in place. Today we call this invention Post-it Notes.
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| Number | Title | Issue Date |
| 4658013 | Analgesic and/or opiate antagonist tripeptide amides and processes for preparation and compositions thereof A genus of tripeptide amides and fifteen species thereof of Examples 4-18, which are useful as analgesics and/or opiate antagonists, three processes for preparation thereof, pharmaceutical compositions thereof, and the three tripeptide amide species of Ex... | 04/14/1987 |
| 4657915 | 1,6-naphthyridine-2(1H)-ones and their use as cardiotonic agents 5-X-7-R'-1,6-Naphthyridine-2(1H)-ones (formula II) or salts thereof, where X is bromo, chloro or hydrazino and R' is hydrogen or methyl, which are useful as cardiotonic agents.... | 04/14/1987 |
| 4650806 | Cardiotonic 5-(heterylcarbonyl)-pyridones 3-Z-5-(Q-CO)-6-methyl-2(1H)-pyridinones (I) or salts thereof, where Q is 2(or 3)-furanyl or 2(or 3)-thienyl when Z is hydrogen or cyano, or where Q is 4(or 3)-pyridinyl or 4(or 3)-pyridinyl having one or two methyl substituents only when Z is cyano, are u... | 03/17/1987 |
| 4647578 | Phototoxic insecticidal compositions and method of use thereof Water insoluble, photodynamic insecticidal compositions comprising the free acids of erythrosin B, phloxin B, rose bengal, octabromofluorescein or fluorescein or the aluminum lakes thereof, optionally including a dispersant, aqueous dispersions of the sam... | 03/03/1987 |
| 4645488 | Syringe for extrusion of wetted, particulate material The invention relates to a syringe for extrusion of a semi-plastic, particulate mass comprising a barrel of flexible material having one or more longitudinal slits therein and provided at its upper end with a piston with means for making positive engageme... | 02/24/1987 |
| 4643840 | Paint stripper compositions Alkaline paint stripper compositions contain either a fibrous material or a combination of a xanthan gum and hectorite clay so as to provide a peelable skin over a painted surface.... | 02/17/1987 |
| 4636820 | Compositions, process and systems 3-[(Substituted-amino)(aryl or heteroaryl)methyl]-1H-indoles which are useful as color-formers in pressure-sensitive carbonless duplicating systems and thermal marking systems are prepared by reacting 3-[(arylsulfonyl)(aryl or heteroaryl)methyl]-1H-indole... | 01/13/1987 |
| 4634772 | 2-[2-(di-lower-alkylamino)-1 -propenyl]-6-methoxy-3-pyridinecarbonitriles, intermediates for cardiotonic agents 2-[2-(di-lower-alkylamino-1-propenyl]-6-methoxy-3-pyridinecarbonitriles, useful as intermediates for cardiotonic agents.... | 01/06/1987 |
| 4634776 | 3-arylcarbonyl-and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles 3-Arylcarbonyl- and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles, useful as analgesic, anti-rheumatic and anti-inflammatory agents, are prepared by reacting a 3-arylcarbonyl- or 3-cycloalkylcarbonylindole with an aminoalkyl halide in the presence of an ac... | 01/06/1987 |
| 4629735 | Compositions containing substituted aminobenzoates and use thereof as inhibitors of lipoxygenase Novel lower-alkyl 2-(hydroxyphenylamino)benzoates, useful as inhibitors of lipoxygenase, are of the formula ##STR1## wherein R is hydrogen, lower-alkyl or lower-alkoxy; R' is hydrogen or lower-alkyl; R" is hydrogen, lower-alkyl or halo; and Alk is lo... | 12/16/1986 |
| 4618684 | Substituted indoles 3-[(Alkoxy)(aryl or heteroaryl)methyl]-1H-indoles which are useful as color formers in pressure-sensitive carbonless duplicating systems and thermal marking systems are prepared by reacting 3-[(arylsulfonyl)(aryl or heteroaryl)methyl]-1H-indoles with alco... | 10/21/1986 |
| 4614649 | Antiplaque saccharin salt dentrifices and method of use thereof Antiplaque dentifrices containing as the antiplaque ingredient the saccharin salt of an amino or quaternary ammonium antimicrobial agent, particularly chlorhexidine saccharin salt or octenidine saccharin salt, and the method of inhibiting, reducing and pr... | 09/30/1986 |
| 4614830 | Esterification process An improvement in the process for esterification of 3,4-dihydroxyphenyl N-alkylaminoalkyl ketones with arylcarboxylic acid chlorides which comprises carrying out the esterification in the presence of a catalytic amount of a 4-di-lower-alkylaminopyridine o... | 09/30/1986 |
| 4610991 | Antihypertensive pyridylaminobenzamide compounds A series of 4-pyridinylaminobenzamides, useful as antihypertensive agents, was prepared from the corresponding 4-pyridinylaminobenzoic acids by reacting the acid chloride of the latter with ammonia or a primary or secondary amine. Alternatively the compou... | 09/09/1986 |
| 4605517 | Method of preparing steroid compounds of controlled particle size The method of preparing a 2-cyano-4,5-epoxy-3-oxo steroid or a steroid fused at the 2- and 3-positions with a heterocyclic ring of controlled particle size which comprises dissolving the steroid in an organic solvent, precipitating th... | 08/12/1986 |
| 4604399 | 5-methyl(or ethyl)-1,6-naphthyridin-2(1H)-one 6-oxides, their preparation and the cardiotonic use thereof 4-R'-5-Q-1,6-naphthyridin-2(1H)-ones (I), where R' is hydrogen or methyl and Q is hydroxymethyl, 1-hydroxyethyl alkanoyloxymethyl or 1-alkanoyloxyethyl, are produced by first reacting 4-R'-5-acetyl(or n-propanoyl)-6-[2-(di-lower-alkylamino]-2(1H)-pyridino... | 08/05/1986 |
| 4599423 | Preparation of 5-(hydroxy- and/or aminophenyl-6-lower-alkyl)-2(1H)-pyridinones Disclosed and claimed is the cardiotonic use of 1-R1 -5-(3-R'-4-R"-phenyl)-6-R-2(1H)-pyridinones (II), where R1 is hydrogen, lower-alkyl or lower-hydroxyalkyl, R is lower-alkyl or hydrogen, and, R' and R" are each hydrogen, amino or ... | 07/08/1986 |
| 4598525 | Glazing system A glazing system comprising a glass pane and a wooden frame, and a beading strip comprised of two co-extruded hardness grades of a rubber or plastic material, the harder material forming a main body portion of the beading strip and the softer grade formin... | 07/08/1986 |
| 4598082 | Antimicrobial (N-1-octyl-4(1H)-pyridinylidine)octanamine and acid addition salts thereof and methods of use and compositions thereof N-[1-(alkyl or arylmethyl)-4(1H)-pyridinylidine]-alkanamine and pharmaceutically acceptable acid addition salts thereof, for example, N-(1-octyl-4(1H)-pyridinylidine)octanamine monohydrochloride salt, which are useful as antimicrobial agents, especially o... | 07/01/1986 |
| 4595762 | 5--bromoalkanoyl-2-oxo-3-pyridinecarbonitriles 3-Q-4-R2 -5-(2-Q'-5-R3 -4-thiazolyl)-6-R1 -2(1H)-pyridinones (I), where R1 is alkyl having from one to four carbon atoms, R2 is hydrogen or methyl, R3 is hydrogen or alkyl having from one to ... | 06/17/1986 |
| 4590194 | 3-[methyl or dimethyl)amino]-6-(pyridinyl)pyridazines and their cardiotonic use 3-(NB)-4-Q-6-PY-pyridazines (I) or salts thereof, which are useful as cardiotonics, are prepared by reacting a 3-halo-4-Q-6-PY-pyridazine with an amine, H-NB, to produce I, where PY is 4- or 3-pyridinyl or 4- or 3-pyridinyl having one or two lower-alkyl s... | 05/20/1986 |
| 4590183 | Gastric cytoprotection with sodium thiosulfate in oral administration of aspirin The method of providing cytoprotection of the gastric mucosa in a mammal receiving aspirin perorally which comprises orally administering either prior to or in combination with aspirin a cytoprotectively effective amount of sodium thiosulfate alone or in ... | 05/20/1986 |
| 4585445 | Hypodermic syringe holder for use with disposal ampoules Hypodermic syringe holders for use in combination with disposable medicament-containing ampoules are adapted to immobilize the ampoules within the syringe holder so as to provide manual aspirating capability.... | 04/29/1986 |
| 4585764 | Gastric cytoprotection with 3,3'-thiobis[propanoic acid] in oral administration of aspirin The method of providing cytoprotection of the gastric mucosa in a mammal receiving aspirin (ASA) perorally which comprises orally administering either prior to or in combination with ASA a cytoprotectively effective amount of 3,3'-thiobis[propanoic acid] ... | 04/29/1986 |
| 4581354 | 3-arylcarbonyl- and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles, compositions and use 3-Arylcarbonyl- and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles, useful as analgesic, anti-rheumatic and anti-inflammatory agents, are prepared by reacting a 3-arylcarbonyl- or 3-cycloalkylcarbonylindole with an aminoalkyl halide in the presence of an ac... | 04/08/1986 |
| 4576729 | Liquid disinfectant laundry detergents Stable liquid disinfectant laundry detergent compositions, having germicidal, cleaning, fabric brightening and anti-soil redeposition properties, contain a non-ionic surfactant, a cryptoanionic surfactant and a quaternary ammonium germicide and, optionall... | 03/18/1986 |
| 4570171 | Electrochromic marking systems 5-[N-(RCO)-N-R1 -amino] or (RCOO)-9-(N-R2 -N-R3 -amino)-12-(RCO)benzo[a]phenoxazines useful as color formers, particularly in electrochromic recording systems, are prepared by the interaction of the corresponding 5-(N-R | 02/11/1986 |
| 4567186 | 5-Heteryl-1,6-naphthyridin-2(1H)-ones, cardiotonic use thereof and intermediates therefor 3-Z-5-Q-1,6-naphthyridin-2(1H)-ones (I) or salts thereof, where Z is hydrogen or cyano, and Q is 2(or 3)-furanyl, 2(or 3)-thienyl, 4(or 3)-pyridinyl or 4(or 3)-pyridinyl having one or two methyl substituents, are useful as cardiotonic agents and correspon... | 01/28/1986 |
| 4565308 | Child resistant powder dispenser This invention relates to powder dispensers of the squeeze bottle type which are so constructed that a small child would be unable to manipulate the dispensing action and would thus be protected from ingestion or inhalation of the dispenser contents.... | 01/21/1986 |
| 4562024 | Process for preparing granulate containing poorly compressible medicinally active matter An improved wet granulation process for preparing compressed tablets, particularly those containing a poorly compressible medicament, e.g., paracetamol and derivatives thereof, the improvement which comprises homogenizing part only of particulate solid ma... | 12/31/1985 |
| 4560753 | 2-Substituted-pyrido[2,3-d]pyrimidin-5(8H)-ones 2-Q-6-Q'-8-R-pyrido[2,3-d]pyrimidin-5(8H)-ones (I), where Q is 4(or 3)-hydroxyphenyl, 4(or 3)-methoxyphenyl, 4(or 3)-pyridinyl or 4(or 3)-pyridinyl having one or two lower-alkyl substituents, R' is hydrogen or alkyl having one to four carbon atoms, Q is h... | 12/24/1985 |
| 4560746 | Ultrafiltration process for purification of dyes useful in foodstuffs The disodium salt of 1-[(6-methoxy-4-sulfo-3-methylphenyl)azo]-2-naphthol-6-sulfonic acid (FD and C Red 40), the disodium salt of 1-[(4-sulfophenyl)azo]-2-naphthol-6-sulfonic acid (FD and C Yellow 6), the trisodium salt of 1-[1-(4-sulfonaphthyl)azo]-... | 12/24/1985 |
| 4560691 | 5-(Phenyl)-1,6-naphthyridin-2(1H)-ones, their cardiotonic use and preparation 1-R-5-Ar-1,6-naphthyridin-2(1H)-ones (I) or salts thereof, where R is hydrogen or methyl, and Ar is phenyl or phenyl substituted by methyl, ethyl, methoxy, ethoxy, hydroxy, amino, acetylamino, methanesulfonylamino, bromo, chloro, fluoro, cyano or carbamyl... | 12/24/1985 |
| 4561001 | Electrochromic marking systems 3-(N-R2 -N-Acylamino)-7-(N-R3 -N-R4 -amino)-10-acylphenothiazines and phenoxazines useful as color formers, particularly in electrochromic recording systems, are prepared by the interaction of the corresponding 3-(N-R... | 12/24/1985 |
| 4559352 | 1,2-Dihydro-2-oxo-5-(hydroxy-and/or amino-phenyl)-nicotinonitriles and cardiotonic use thereof 1-R1 -3-amino-5-(3-R'-4-R"-phenyl)-6-R-2(1H)-pyridinones or salts thereof, which are useful as cardiotonics, where R1 is hydrogen, lower-alkyl, or lower-hydroxyalkyl, R is hydrogen or lower-alkyl, and, R' and R" are each hydrogen, hy... | 12/17/1985 |
| 4559347 | 3-Substituted-5-alkyl-1,6-naphthyridin-2(1H)-ones, cardiotonic use and preparation thereof 1-R"-3-Q-4-R'-5-R-1,6-naphthyridin-2(1H)-ones (I) or salts thereof, where R is lower-alkyl, R' is hydrogen or methyl, R" is hydrogen or lower-alkyl, and Q is hydrogen, hydroxy, amino, cyano, carbamyl, carboxy or aminocarbamyl, are useful as cardiotonic ag... | 12/17/1985 |
| 4559151 | Antistatic fabric conditioner compositions and method Antistatic and fabric softener compositions for application to textile fabrics comprises a combination of an N,N-dialkyl-N,N-di-lower-alkyl quaternary ammonium salt either alone or in combination with an N-long-chain alkylamido-lower-alkyl-N,N-di-lower-al... | 12/17/1985 |
| 4557898 | Method of disinfecting and sterilizing with hydrogen peroxide compositions Aqueous acidic disinfecting and sterilizing compositions containing hydrogen peroxide, a surfactant and an aqueous alcoholic mixture of a tertiary amine and a fatty acid alkanolamide are non-irritating, have in-use stability and are effective for cold and... | 12/10/1985 |
| 4551135 | Syringe for extrusion of semi-plastic material The invention comprises a syringe for extrusion of a semi-plastic mass, or a mass having a paste-like consistency. In a preferred embodiment, the syringe is so-designed to permit mixing of two components of a plasticizable mixture within the syringe barre... | 11/05/1985 |
| 4550855 | Moist tissue soft pack dispensers This invention relates to compact, easily transportable, moist tissue or towelette dispensers which are so designed that they maintain the tissues contained within the dispenser in moist condition for exceptionally long periods of time, thus providing lon... | 11/05/1985 |
