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An aircraft having vertical takeoff and landing capability provided with at least first and second laterally extending paddle wheels rotatable on a central axis perpendicular to the longitudinal axis of the aircraft fuselage and between its nose and tail.
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| Number | Title | Issue Date |
| D657096 | Pet carrier | 04/03/2012 |
| D655702 | Motor vehicle cell phone holder | 03/13/2012 |
| 8127715 | Mobile pet bed/carrier The present invention relates to a mobile pet bed wherein the top and bottom units of the mobile pet bed are reversibly attached to each other. When the top unit is removed from the bottom unit the mobile pet bed functions similarly to a traditional pet bed. When th... | 03/06/2012 |
| 8091594 | Hands free device for filling tanks The present invention relates to novel devices and methods of filling tanks designed for holding non-hazardous fluids, especially tanks on recreational vehicles. In a preferred embodiment, the tank to be filled is a water tank. The device of the present invention in... | 01/10/2012 |
| 8058228 | Leptin peptide antagonists Disclosed herein are peptides comprising a leptin sequence and methods for their use in preventing ObR signaling in a leptin-responsive cell. A leptin peptide of the present invention binds to but does not activate ObR signaling in a leptin-responsive cell, thereby ... | 11/15/2011 |
| 8043805 | Detection of high grade dysplasia in cervical cells Methods of using probes and probe sets for the detection of high grade dysplasia and carcinoma in cervical cells are described. Methods of the invention include hybridizing one or more chromosomal probes to a biological sample obtained from a subject and detecting t... | 10/25/2011 |
| 8034577 | Methods and probes for detecting esophageal cancer Probe sets and methods of using probes and probe sets for selectively detecting high grade dysplasia and esophageal adenocarcinoma or low grade dysplasia from biologic samples are described. Methods of the invention include contacting a biological sample obtained fr... | 10/11/2011 |
| 8022229 | Process for the preparation of alkyl 5-(dicarboximido) levulinate and alkyl 4-oxo-pentenoate A method of manufacturing esters of dicarboxyimidolevulinic acid and alkyl trans-4-oxo-2-pentenoate. This method includes two reaction steps, wherein the first step of said two reaction steps is a bromination of alkyl-levulinate, to obtain alkyl-(3 and 5)-bromolevul... | 09/20/2011 |
| 7998678 | Methods for the detection of lung cancer Probe sets and methods of using probes and probe sets for the detection of cancer are described. Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if cancer cells are pre... | 08/16/2011 |
| 7992602 | Device, kit and method for adding salt to a water softener system The present invention relates to devices, kits and methods to aid the home owner in the transport of salt to their cellar-based water softening system. The device of the present invention uses rectangular piping because of the greater ease of supporting the piping a... | 08/09/2011 |
| 7968527 | Inhibition of FGF signaling Methods and compositions for inhibiting FGF signaling are described. Methods of the invention include contacting an FGF-responsive cell with exogenous heparan sulfate 6-O endosulfatase (Sulf1) in an amount effective to modify endogenous heparan sulfate, thereby inhi... | 06/28/2011 |
| 7935350 | Ii-key/Her-2/neu hybrid cancer vaccine Provided are methods and compositions for treating cancer in humans, the cancer being characterized by expression of Her-2/neu. The methods involve vaccinating a patient with an Ii-Key/MHC class II hybrid construct and thereby stimulating an immune response to the n... | 05/03/2011 |
| 7927801 | Nucleic acid probes and methods for detecting parasites This invention relates to novel nucleic acid probes and methods for detecting Plasmodium parasites as well as detecting different Plasmodium parasites selectively from one another. ... | 04/19/2011 |
| 7906626 | Immunological control of β-amyloid levels in vivo Disclosed are bispecific antibodies comprising a first antibody binding specificity which confers the ability of the bispecific antibody to cross the blood-brain barrier, and a second antibody specificity conferring the ability of the bispecific antibody to bind to ... | 03/15/2011 |
| 7845083 | Stabilized T-square The present invention relates to a device for easily and accurately marking, scoring and cutting drywall sheet material, the device having a general appearance of a T-square and comprising gripping pins for securely holding the T-square on the sheet material to be m... | 12/07/2010 |
| 7867725 | Monoclonal antibodies against osteopontin The present invention relates to reagents and methods for the detection of osteopontin fragments and distinguishing them from each other and from the full-length osteopontin protein. The present invention also relates to assays for the determination of the presence ... | 01/11/2011 |
| 7843770 | Interval timer The present invention is directed towards a device and method of use for ensuring that persons who need to stay on a schedule can do so without constantly looking at a clock. The device is a programmable electronic device wherein the user can set a schedule time, an... | 11/30/2010 |
| 7757540 | Device and method for testing torque wrenches The present invention is directed towards inexpensive and reliable devices and methods for testing the calibration of torque wrenches. ... | 07/20/2010 |
| 7749966 | Immunological modulation of insulin-like growth factor 1 for cancer prevention/treatment and prolonging longevity Provided is a simple and safe immunization procedure to reduce cancer incidence and increase longevity by modulating IGF-1 levels in the body. Described are cancer preventive vaccines and methods that elicit circulating antibodies specific to insulin-like growth fac... | 07/06/2010 |
| 7736910 | One-step production of gold sols The present invention comprises novel “one-step” methods for the production of gold sol and gold sol conjugates. The methods disclosed herein produce gold sol and colloidal gold conjugates with product with yields on the order of about 20 ODs. Since current meth... | 06/15/2010 |
| 7712437 | Mobile pet bed/carrier The present invention relates to a mobile pet bed wherein the top and bottom units of the mobile pet bed are reversibly attached to each other. When the top unit is removed from the bottom unit the mobile pet bed functions similarly to a traditional pet bed. When th... | 05/11/2010 |
| 7709271 | Method and device for immunoassay The present invention relates to a method and a device for determining a concentration of a biological active substance in a sample by the means of an enzyme-linked immunosorbent assay (ELISA). The device comprises a solid support within a tubing for binding an immu... | 05/04/2010 |
| 7709216 | Methods for preventing or reducing ischemia/reperfusion induced myocardial cell death Provided herein are methods relating to inhibition of PUMA function for preventing or reducing myocardial cell death. A method for preventing or reducing ischemia/reperfusion induced myocardial cell death in a human is provided as are methods for identifying pharmac... | 05/04/2010 |
| 7704946 | Reversible inhibition of pyramidal gap junction activity The present invention relates to a novel method of inhibiting gap junction-mediated signaling in pyramid cells. Pyramidal gap junctions are quickly and reversibly inhibited by beta-amyloid or biologically active fragments thereof. The present invention also relates ... | 04/27/2010 |
| 7632393 | Total organic carbon (TOC) analyzer The invention disclosed is a total organic carbon (TOC) analyzer comprised of an electrochemical cell comprising a diamond-film electrode (2) doped with boron or other conductivity including material. The diamond-film electrode is the working electrode and ca... | 12/15/2009 |
| 7612043 | Method of reducing or inhibiting ObR signaling using a leptin antagonist consisting of SEQ id No: 2 Disclosed herein are peptides comprising a leptin sequence and methods for their use in preventing ObR signaling in a leptin-responsive cell. A leptin peptide of the present invention binds to but does not activate ObR signaling in a leptin-responsive cell, thereby ... | 11/03/2009 |
| 7574769 | Rearview mirror wiper system In one aspect, the invention relates a rearview mirror wiper system suitable for use on, for example, large tractor-trailer trucks, delivery trucks, vans, motor homes, cars and other motor vehicles. The rearview wiper system of the present invention has many advanta... | 08/18/2009 |
| 7553832 | Methods and compositions for specific inhibition of protein splicing by small molecules The present invention relates to compositions (i.e., various organic small molecules as exemplified herein) and methods for the inhibition of protein splicing and especially relates to the inhibition of protein autosplicing of intein-containing proteins. Additionall... | 06/30/2009 |
| D594597 | Hair curler warmer system | 06/16/2009 |
| 7541431 | Cristin/R-spondin ligands active in the Wnt signaling pathway and methods, compositions and kits relating thereto The present invention relates to compositions and method for the modulation of Wnt pathway signaling. The Wnt signaling pathway is instrumental in the regulation of cell proliferation, differentiation and morphogenesis. ... | 06/02/2009 |
| 7541334 | Hybrid peptides modulate the immune response The present invention provides an MHC class II antigen presentation enhancing hybrid polypeptide. The hybrid has an N-terminus comprising the mammalian Ii key peptide LRMKLPKPPKPVSKMR (SEQ ID NO: 1) and modifications thereof which retain antigen presentation enhanci... | 06/02/2009 |
| D591069 | Beach chair | 04/28/2009 |
| 7517645 | Detection of high grade dysplasia in cervical cells Methods of using probes and probe sets for the detection of high grade dysplasia and carcinoma in cervical cells are described. Methods of the invention include hybridizing one or more chromosomal probes to a biological sample obtained from a subject and detecting t... | 04/14/2009 |
| 7481001 | Rolling T-square drywall cutter The present invention relates to a device for easily and accurately scoring and cutting drywall sheet material, the device having a general appearance of a T-square and comprising rollers under the portion of the device that contacts the edge of the drywall sheet, a... | 01/27/2009 |
| 7481687 | Jet propulsion outboard and inboard motor The present invention relates to a novel and non-obvious propulsion system for watercraft, especially, but not limited to, watercraft less than about 50 feet in length. Propulsion system of the present invention provides a system that is less prone to being impeded ... | 01/27/2009 |
| D584092 | Window blind cover | 01/06/2009 |
| 7458968 | Device for neurocryo analgesia and anesthesia A catheter system and method for selectively cooling or freezing target neuronal tissue to induce lesions along the neuroaxis and produce cryoanalgesia by impairing nerve conduction of the targeted neuronal tissue. The system includes a catheter that has cryogenic c... | 12/02/2008 |
| 7434577 | Solar air heater This invention provides novel devices and methods for the heating of air with solar radiant energy. The devices of the present invention feature a housing partitioned into essentially isolated sections wherein the sections are in fluid communication with each other ... | 10/14/2008 |
| 7413884 | Immunological control of β-amyloid levels in vivo Disclosed are antibodies which catalyze hydrolysis of β-amyloid. Antibodies generated are characterized by the amide linkage which they hydrolyze. Methods of generating the antibodies by using β-amyloid peptides which incorporate transition state analogs are also ... | 08/19/2008 |
| 7407929 | Leptin peptide antagonists Disclosed herein are peptides comprising a leptin sequence and methods for their use in preventing ObR signaling in a leptin-responsive cell. A leptin peptide of the present invention binds to but does not activate ObR signaling in a leptin-responsive cell, thereby ... | 08/05/2008 |
