Bizarre Patents
A small umbrella which may be removably attached to a beverage container in order to shade the beverage container from the direct rays of the sun.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8158771 | Host cell protein knock-out cells for production of therapeutic proteins The present invention relates to methods and means for making Vitamin K-dependent protein compositions which are devoid or substantially devoid of protein contaminants. In particular, methods and means useful for the reduction or elimination of protein contaminants ... | 04/17/2012 |
| 8148412 | Heteroaromatic glucokinase activators The present invention describes 2,3-di-substituted N-heteroaromatic propionamides, of Formula (I) wherein the substitution at the 3-position is an optionally substituted phenyl ring and the substitution at the 2-position is an alkyl or cycloalkyl group; pharmaceutic... | 04/03/2012 |
| 8138185 | Urea glucokinase activators This application relates to novel urea glucokinase activators and use of the compounds of the invention for preparation of a medicament for the treatment of various diseases, e.g. for the treatment of type 2 diabetes. Further encompassed is a pharmaceutical composit... | 03/20/2012 |
| 8063081 | Aryl carbonyl derivatives as therapeutic agents This invention relates to aryl carbonyl derivatives which are activators of glucokinase which may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial. ... | 11/22/2011 |
| 7999114 | Dicycloalkylcarbamoyl ureas as glucokinase activators This invention relates to dicycloalkylcarbamoyl ureas of formula (I), which are activators of glucokinase and thus may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial. | 08/16/2011 |
| 7897734 | Method for the production of proteins The present invention relates to a process for the purification of a protease. ... | 03/01/2011 |
| 7897628 | Aryl carbonyl derivatives as therapeutic agents This invention relates to aryl carbonyl derivatives which are activators of glucokinase which may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial. ... | 03/01/2011 |
| 7884210 | Ureido-thiazole glucokinase activators The invention provides a compound of general formula (I) wherein the compounds are of the class ureido-thiazole glucokinase activators, useful for the treatment of various diseases, for example, type 2 diabetes. ... | 02/08/2011 |
| 7884181 | Pharmaceutical formulation comprising crystalline insulin and dissolved insulin The invention provides a pharmaceutical formulation and a method for preparing the formulation. ... | 02/08/2011 |
| 7879893 | Ligands for the HisB10 Znsites of the R-state insulin hexamer The present invention relates to novel ligands for the HisB10 Zn2+ sites of the R-state insulin hexamer having the formula A-B-C-D-X (III), wherein: A is a chemical group which reversibly binds to a HisB10 Zn2+ sites of an... | 02/01/2011 |
| 7872139 | Heteroaryl-ureas and their use as glucokinase activators This invention relates to compounds of formula (I) which are activators of glucokinase and thus may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity i... | 01/18/2011 |
| 7851636 | Heteroaryl-ureas and their use as glucokinase activators This invention relates to compounds of formula (I) which are activators of glucokinase and thus may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity i... | 12/14/2010 |
| 7598391 | Heteroaryl-ureas and their use as glucokinase activators This invention relates to compounds of formula (I) which are activators of glucokinase and thus may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity i... | 10/06/2009 |
| 7582769 | Dicycloalkyl urea glucokinase activators Dicycloalkyl urea glucokinase activators compounds are glucokinase inhibitors useful for the treatment of diabetes. (I) ... | 09/01/2009 |
| 7576062 | Compounds with growth hormone releasing properties Disclosed are compounds of formula I wherein R1, R2, R5, R6, R7, R8, G, J, L, M, a, b, c, d, e, and f are as defined in the specification, and compositions c... | 08/18/2009 |
| 7541373 | Aryl carbonyl derivatives as therapeutic agents This invention relates to aryl carbonyl derivatives which are activators of glucokinase which may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial. ... | 06/02/2009 |
| 7384967 | Aryl carbonyl derivatives as therapeutic agents This invention relates to aryl carbonyl derivatives which are activators of glucokinase which may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial. ... | 06/10/2008 |
| 7358238 | Pharmaceutical use of fused 1,2,4-triazoles The use of fused 1,2,4-triazoles for modulating the activity of 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) and the use of these compounds as pharmaceutical compositions has been described. Also a novel class of fused 1,2,4-triazoles, their use in therapy, p... | 04/15/2008 |
| 7332508 | Substituted homopiperidine, piperidine or pyrrolidine derivatives A novel class of substituted homopiperidine, piperidine and pyrrolidine derivatives, methods for their preparation, pharmaceutical compositions comprising them and use thereof in the treatment of disorders related to the histamine H3 receptor. More particularly, the... | 02/19/2008 |
| 7317000 | Glucose-dependent insulins The present invention relates to insulin derivatives having a built-in glucose sensor and a polyol moiety, capable to deliver insulin from an injected depot of an insulin derivative according to the invention as a function of the glucose concentration in the surroun... | 01/08/2008 |
| 7294626 | Piperazines The present invention relates, inter alia, to novel piperazines of the following formula: to the use of these compounds in the preparation of pharmaceutical compositions, to pharmaceutical compositions comprising... | 11/13/2007 |
| 7235538 | Heterocyclic compounds, which are inhibitors of the enzyme DPP-IV The present invention relates to therapeutically active and selective inhibitors of the enzyme DPP-IV, which are of formula I wherein each n is one or two independently and R1, R2, R3 | 06/26/2007 |
| 7220877 | Compounds, their preparation and use A novel class of dicarboxylic acid derivatives, the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be useful i... | 05/22/2007 |
| 7192952 | Heterocyclic compounds that are inhibitors of the enzyme DPP-IV The present invention relates to therapeutically active and selective inhibitors of the enzyme DPP-IV of formula I, pharmaceutical compositions comprising the compounds and the use of such compounds for and the manufacture of medicaments for treating diseases that a... | 03/20/2007 |
| 7186721 | Substituted hexahydropyrrolo[1,2-a]pyrazines, octahydropyrido[1,2-a]-pyrazines and decahydropyrazino[1,2-a]azepines Novel substituted hexahydropyrrolo[1,2-a]pyrazines, octahydropyrido[1,2-a]-pyrazines and decahydropyrazino[1,2-a]azepines, use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds, and a method of treatment employin... | 03/06/2007 |
| 7129268 | Peroxisome proliferator activated receptor-active arylene acetic acid derivatives Novel compounds of the general formula (I), wherein Ar, R1, R2, X1, X2, Y1, Y, and Z are as defined in the specification, the use of these compounds as pharm... | 10/31/2006 |
| 7115624 | Method of inhibiting protein tyrosine phosphatase 1B and/or T-cell protein tyrosine phosphatase 4 and/or other PTPases with an Asp residue at position 48 The present invention provides a method of inhibiting a member of a family of Protein Tyrosine Phosphatases (PTPases, PTPs) such as PTP1B, TC-PTP, CD45, SHP-1, SHP-2, PTPα, PTPε, PTPμ, PTPδ, PTPσ, PTPζ, PTPβ, PTPD1, PTPD2, PTPH1, PTP-MEG1, PTP-LAR, and HePTP ... | 10/03/2006 |
| 7067517 | Use of compounds for decreasing activity of hormone-sensitive lipase Use of compounds to inhibit hormone-sensitive lipase, pharmaceutical compositions comprising the compounds, methods of treatment employing these compounds and compositions, and novel compounds. The present compounds are inhibitors of hormone-sensitive lipase and may... | 06/27/2006 |
| 7067530 | Compounds, their preparation and use Novel compounds of general formula (I), the use of these compounds as medicaments, pharmaceuticaly compositions comprising the compounds and methods of treatment employing these compounds and compostiones. The present compounds may be useful in the treatment and/or ... | 06/27/2006 |
| 7064145 | Inhibition of beta cell degeneration Methods for preventing beta cell degeneration, such as necrosis or apoptosis of beta cells in a subject, comprising administering a DPP-IV inhibitor to a subject in need thereof. The invention furthermore relates to a method for increasing the number and/or the size... | 06/20/2006 |
| 7064135 | Substituted piperidines A novel class of substituted piperidines, pharmaceutical compositions comprising them and use thereof in the treatment of diseases and disorders related to the histamine H3 receptor. More particularly, the compounds are useful for the treatment of diseases and disor... | 06/20/2006 |
| 7056684 | Protein-protein interactions of p66 The present invention relates to (a) the establishment of a direct consequence to the mitochondrial import of phosphorylated p66ShcA and its association with prohibitin, and (b) to a potential function for the prohibitin-p66ShcA complex in the ... | 06/06/2006 |
| 7037905 | Pharmaceutical use of boronic acids and esters thereof Use of compounds to inhibit hormone-sensitive lipase, the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds, method of treatment employing these compounds and compositions, and novel compounds. The present co... | 05/02/2006 |
| 6994261 | Support for a cartridge for transferring an electronically readable item of information from the cartridge to an electronic circuit A support for a medication cartridge provided with one or more electronically readable items of information carrying areas is disclosed. The support disclosed has a number of closely spaced mutually electrically insulated conductors embedded in an electrically insul... | 02/07/2006 |
| 6972294 | Compounds, their preparation and use Disclosed are novel compounds of formula (I) wherein A1, A2, Ar, R5, R6, R8, M, Q, Y, Z, k, m and n are as defined in the specification. These compounds are useful ... | 12/06/2005 |
| 6960610 | Use of glycogen phosphorylase inhibitors for treatment of cardiovascular diseases The present invention provides methods which may effectively be used in the treatment and prevention of early cardiac and early cardiovascular diseases, for example of ischemic origin, such as left ventricular hypertrophy, coronary artery disease, essential hyperten... | 11/01/2005 |
| 6951878 | Benzo[b]thiophenyl or tetrahydro-benzo[b]thiophenyl modulators of protein tyrosine phosphatases (PTPases) The present invention provides novel compounds, novel compositions, methods of their use, and methods of their manufacture, where such compounds are pharmacologically useful inhibitors of Protein Tyrosine Phosphatases (PTPase's) such as PTP1B, CD45, SHP-1, SHP-2, PT... | 10/04/2005 |
| 6939880 | Compounds with growth hormone releasing properties Compounds of peptide mimetic nature having the general formula I wherein a and b are independently 1 or 2, R1 and R2 are independently H or C1-6alkyl, G and J are independently, inter a... | 09/06/2005 |
| 6906060 | Substituted hexahydropyrrolo[1,2-a]pyrazines, octahydropyrido[1,2-a]-pyrazines and decahydropyrazino[1,2-a]azepines Novel substituted hexahydropyrrolo[1,2-a]pyrazines, octahydropyrido[1,2-a]-pyrazines and decahydropyrazino[1,2-a]azepines, use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds, and a method of treatment employin... | 06/14/2005 |
| 6869967 | Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be useful in th... | 03/22/2005 |
