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Attorney: Wiley Rein & Fielding LLP


Number of patents: 22
Last date: January 30, 2007

NumberTitleIssue Date
7169913Engineered secreted alkaline phosphatase (SEAP) reporter genes and polypeptides
The invention provides a novel reporter gene (mSEAP) capable of being expressed in a mammal for extended periods of time. Nucleic acids encoding the reporter gene, cells and vectors comprising the nucleic acids, and methods of using the reporter gene to identify exp...
01/30/2007
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01/30/2007
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12/26/2006
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12/19/2006
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12/19/2006
7132396Compositions which can be used for regulating the activity of parkin
The present invention relates to novel compounds and their uses, in particular their pharmaceutical or diagnostic uses or their use as pharmacological targets. More particularly, the present invention relates to a novel protein, referred to as PAP1, as well as to no...
11/07/2006
7124526Overhead highway billboard and marketing method
A billboard advertising system is disclosed. The billboard advertising system includes an overhead sign structure at least partially traversing a roadway, said overhead sign structure having forward and rearward faces relative to oncoming vehicle traffic of the road...
10/24/2006
7125212Method and device for adapting a cargo container to directly interface with an aircraft cargo bay
The present invention relates generally to a skid assembly for use with a cargo container. In one particular embodiment, the skid assembly comprises an elongate member having an upper surface, a lower surface, and a side surface; a plurality of side extensions space...
10/24/2006
71237043-Way call detection system
Disclosed herein is a three-way call detection system and method for detecting the addition of a third party to a pre-existing telephonic connection between a first party and a second party. The system comprises: a meter for measuring the amplitude of a line voltage...
10/17/2006
7101362Steerable and shapable catheter employing fluid force
A catheter employing fluid force to steer and/or shape the catheter. In one particular implementation, the catheter includes at least one actuating lumen operably associated with the shaft of the catheter. The at least one actuating lumen is in fluid communication w...
09/05/2006
7033826Recombinant adenoviruses, use thereof for preparing AAVS, complementary cell line, and pharmaceutical compositions containing said adenoviruses
A recombinant adenovirus in which the expression of a nucleic acid sequence coding for at least one homologous or heterologous gene of viral origin is placed under the control of an inducible promoter, is disclosed. The use of such recombinant adenoviruses for prepa...
04/25/2006
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03/01/2005
6723315Method for treating amyotrophic lateral sclerosis
The invention concerns a novel method for treating motor neuron diseases and particularly amyotrophic lateral sclerosis. It consists more particularly in the systemic administration of expression systems of neurotrophic factors. ...
04/20/2004
6669942Defective adenoviruses including a therapeutic gene and an immunoprotectove gene
Novel adenovirus-derived viral vectors, the preparation thereof, and the use of such vectors in gene therapy, are disclosed. In particular, defective adenoviruses having a genome that includes a first recombinant DNA containing a therapeutic gene and a se...
12/30/2003
6638502Adenovirus-mediated intratumoral delivery of an angiogenesis antagonist for the treatment of tumors
The present invention relates to gene therapy for the treatment of tumors. The invention more particularly relates to introduction of a gene encoding an anti-angiogenic factor into cells of a tumor, for example with a defective adenovirus vector, to inhib...
10/28/2003
6598162Method for combining transfer functions with predetermined key creation
A method for combining transfer functions with predetermined key creation. In one embodiment, digital information, including a digital sample and format information, is protected by identifying and encoding a portion of the format information. Encoded dig...
07/22/2003
6549229Small, portable, self-contained, video teleconferencing system
The present Invention relates to a portable, self-contained, briefcase-sized device capable of transmitting and receiving encrypted or unencrypted video teleconferencing communications over a variety of telecommunications mediums. The system contains a li...
04/15/2003
6522767Optimization methods for the insertion, protection, and detection of digital watermarks in digitized data
The implementations of digital watermarks can be optimally suited to particular transmission, distribution and storage mediums given the nature of digitally-sampled audio, video and other multimedia works. Watermark application parameters can be adapted t...
02/18/2003
6420170Recombinant adenoviruses containing an inducible promoter controlling a gene of viral origin
A recombinant adenovirus in which the expression of a nucleic acid sequence coding for at least one homologous or heterologous gene of viral origin is placed under the control of an inducible promoter, is disclosed. The use of such recombinant adenoviruse...
07/16/2002
6410298Adenovirus vectors and method for reducing homologous recombination phenomena
The invention concerns a method for reducing recombination phenomena among nucleic acids. It also concerns the use of said method for producing defective viruses not contaminated by replication particles. The invention further concerns novel viral constru...
06/25/2002
6410273Method for producing methylated DNA
The invention discloses the preparation of DNA, in particular plasmid DNA. More particularly it concerns the production of bacterial plasmid DNA to be used in gene therapy, in the form of plasmid, minicircle supercoiled, loose or linear....
06/25/2002
6387670Method for producing recombinant virus
The invention concerns a method for producing recombinant virus. This method is based on the use of baculovirus for providing the complementary functions. It also concerns constructs used for implementing this method, the producing cells, and the resultin...
05/14/2002
 
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