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| Number | Title | Issue Date |
| 7601269 | On-chip sample preparation for whole blood analysis A novel filter-less separation technique for separating suspended particles from a solution is disclosed. More specifically, an on-chip bioparticle separator is disclosed, which relies on the differential force exerted by application of a series of high magnitude, s... | 10/13/2009 |
| 7332288 | Methods and reagents for the rapid and efficient isolation of circulating cancer cells A highly sensitive assay is disclosed which combines immunomagnetic enrichment with multiparameter flow cytometric and immunocytochemical analysis to detect, enumerate and characterize carcinoma cells in the blood. The assay can detect one epithelial cell or less in... | 02/19/2008 |
| 7282180 | Devices and methods to image objects Devices and methods for automated collection and image analysis are disclosed that enable identification or classification of microscopic objects aligned or deposited on surfaces. Such objects, e.g. detectably labeled rare target cells, are magnetically or non-magne... | 10/16/2007 |
| 7056657 | Apparatus and methods for magnetic separation Separation apparatus and method for separating magnetic and/or magnetically-labeled particles from a test medium. Test medium within a reaction chamber is caused to flow past a collecting surface, and a high-gradient magnetic field is applied to the surface t... | 06/06/2006 |
| 7011794 | Upon a cartridge for containing a specimen sample for optical analysis An improved cartridge for holding a fluid sample with a small volume is disclosed herein. The cartridge has a test chamber and a vestibule through which the test fluids are inserted into the test chamber. Improved grips are flared-out to aid manipulation. The handle... | 03/14/2006 |
| 6890426 | Magnetic separation apparatus and methods Apparatuses and methods for separating, immobilizing, and quantifying biological substances from within a fluid medium. Biological substances are observed by employing a vessel (6) having a chamber therein, the vessel comprising a transparent collection wall ... | 05/10/2005 |
| 6861259 | Method of using a cartridge for containing a specimen sample for optical analysis A cartridge for holding a test specimen with an extremely small volume. The cartridge has a test chamber and a vestibule through which the test fluids are inserted into the test chamber. The cartridge has a stopper having a pair of seals, the first of which seals th... | 03/01/2005 |
| 6364844 | Diagnostic system for determining and/or monitoring physiological conditions in mammals Improvements in a diagnostic system for determining and/or monitoring a physiological condition in a female mammal are disclosed. The system comprises: (a) a read only memory means for storing a diagnostic program for determining the fertility state of th... | 04/02/2002 |
| 6127187 | Apparatus and method for analyzing blood samples Apparatus for analyzing blood or the like has a centrifuge rotor (10) with a means for visibly holding a sample, and a scanning arm (32) which traverses the rotor and includes a means (38) for sending light to the sample to detect the sample component int... | 10/03/2000 |
| 4689304 | Air/liquid detection device for blood sample analysis An air/fluid sensing device useful in apparatus for analyzing biological material. The device includes one or more light sources directed at a surface of a container defining an interface with the space enclosed thereby. Depending on whether fluid is pres... | 08/25/1987 |
| 4632908 | Heating system for rotating members A heating system for heating a rapidly rotating article, including strobe means capable of emitting radiant energy and positioned to radiate energy onto the article, a light source positioned to illuminate a temperature-sensing means on the article, light... | 12/30/1986 |
| 4610142 | Apparatus and method for adjusting a curie effect temperature sensing system An apparatus and method for controlling the operating temperatures and differential temperature of a curie effect temperature sensing switch is disclosed. The temperature switch is adapted to provide temperature control of a cold plate in a reagent refrig... | 09/09/1986 |
| 4602007 | Salicylate culture media for inactivation of bacterial growth inhibitors This invention encompasses methods and reagents for inactivation of bacterial growth inhibitors present in blood, serum or plasma. It has been found that salicylates and closely related compounds will neutralize bacterial growth inhibitors present in the ... | 07/22/1986 |
| 4593089 | Fluorescent polarization immunoassay utilizing substituted triazinylaminofluorescein aminoglycosides This disclosure relates to a method and reagents for determining ligands in biological fluids such as serum, plasma, spinal fluid, amnionic fluid and urine. In particular, this disclosure relates to a fluorescent polarization immunoassay procedure and to ... | 06/03/1986 |
| 4585862 | Fluorescence polarization immunoassay This disclosure relates to a method and reagents for determining ligands in biological fluids such as serum, plasma, spinal fluid, amnionic fluid and urine. In particular, this disclosure relates to a fluorescence polarization immunoassay procedure and to... | 04/29/1986 |
| 4559173 | N-substituted dibenz[b,f]azepine salts Carbamazepine-thiophosphonate conjugates for use as enzyme inhibitors having the formula: ##STR1## wherein Z is a biologically compatible counter ion, n is an integer from 2 to 6 and R and R1 are each lower alkyl.... | 12/17/1985 |
| 4543412 | Phenobarbital enzyme inhibitors Phenobarbital conjugates for use as enzyme inhibitors having the formula: ##STR1## wherein Z is a biologically compatible counter ion, n and m is an integer from 2 to 6 and R and R1 are each lower alkyl.... | 09/24/1985 |
| 4510251 | Fluorescent polarization assay for ligands using aminomethylfluorescein derivatives as tracers This disclosure relates to a method for determining ligands in biological fluids such as serum, plasma, spinal fluid, amnionic fluid and urine, wherein a novel class of aminomethylfluorescein derivative tracer compounds are employed as reagents in fluores... | 04/09/1985 |
| 4504579 | Stabilized peroxidase compositions Novel stable peroxidase compositions are disclosed which are useful as reagents in enzyme immunoassay procedures. In particular the novel peroxidase compositions contain a stabilizer selected from the group consisting of gentamicin, amikacin and tobramyci... | 03/12/1985 |
| 4497900 | Immunoassay for Neisseria gonorrhoeae antigens The present disclosure relates to a solid phase immunoassay for the detection of Neisseria gonorrhoeae antigens in a clinical specimen, wherein the Neisseria gonorrhoeae antigens to be determined are coated or adsorbed on the solid phase.... | 02/05/1985 |
| 4497899 | Immunoassay for Chlamydia trachomatis antigens The present disclosure relates to a solid phase immunoassay for the detection of Chlamydia trachomatis antigens in a clinical specimen, wherein the Chlamydia trachomatis antigens to be determined are coated or adsorbed on the solid phase.... | 02/05/1985 |
| 4495293 | Fluorometric assay A method is provided to fluorometrically determine a ligand in an assay solution containing the ligand, reagent system and a fluorescer wherein the intensity of the fluorescer emitted by the assay solution is related to the change in the transmittive prop... | 01/22/1985 |
| 4492762 | Fluorescent polarization immunoassays Improvement in fluorescent polarization immunoassays for substances in blood plasma or serum comprising conducting the assays in dilute anionic surfactant solutions which disrupt the fluorescent bilirubin serum albumin complex without disturbing the antib... | 01/08/1985 |
| 4491660 | Matrix polymers for binding endotoxins An endotoxin binding material affixed to a support is disclosed. One embodiment is a matrix material capable of binding endotoxins and comprising a polar, water-insoluble, high molecular weight polymer support to which is attached groups which adsorb endo... | 01/01/1985 |
| 4489452 | Prenatal mattress A prenatal mattress enabling a pregnant woman to lie more comfortably and safely upon her abdomen during the pregnancy term is disclosed. The mattress can comprise a lower layer of cloth carrying releasable fasteners, a fluid-fillable abdominal cushion, a... | 12/25/1984 |
| 4476228 | Determination of unsaturated thyroxine binding protein sites using fluorescence polarization techniques This invention encompasses a method for measuring unsaturated thyroxine binding protein sites in a sample comprising intermixing with the sample an effective amount of fluorescent labeled tracer having binding affinity for thyroxine binding proteins and t... | 10/09/1984 |
| 4382306 | Prenatal mattress A prenatal mattress enabling a pregnant woman to lie more comfortably and safely upon her abdomen during the pregnancy term is disclosed. The mattress can comprise a lower layer of cloth carrying releasable fasteners, an abdominal cushion, a head cushion,... | 05/10/1983 |
