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Patent No. 5979328

Vehicular Impact Signaling Device

An apparatus for the deployment of a visible plume to alert other motorists that a proximate motor vehicle has been involved in a collision.

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Attorney: White, Esq.; John P.


Number of patents: 89
Last date: May 29, 2007

1      
NumberTitleIssue Date
7223599Immortalization of human post-mitotic cells
The present invention provides an immortalized human cardiomyocyte cell line. The present invention further provides a method for preparing a human immortalized cell line derived from a post-mitotic primary cell culture. ...
05/29/2007
7219016Systems and methods for automated analysis of cells and tissues
Systems and methods for rapidly analyzing cell containing samples, for example to identify morphology or to localize and quantitate biomarkers are disclosed. ...
05/15/2007
RE39616Aminoindan derivatives
This invention is directed to compounds of the following formula: wherein when a is 0, b is 1 or 2; when a is 1, b is 1, m is from 0-3, X is O or S, Y is halogeno, R1 is hydrogen C1-4 alkyl, R2 is...
05/08/2007
7198954Methods for predicting pregnancy outcome in a subject by hCG assay
The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present invention further provides a method for determining the amount of early ...
04/03/2007
7170029Method and apparatus for deflashing of integrated circuit packages
This invention relates to a method and apparatus for deflashing integrated circuit (IC) packages by laser irradiation. The method and apparatus include two lasers scanning flash area for performing deflashing operation. CO2 laser is used to remove top lay...
01/30/2007
7163802Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
The present invention provides processes for determining the molecular weight of glatiramer acetate and other copolymers. The present invention further provides a plurality of molecular weight markers for determining the molecular weight of glatiramer acetate and ot...
01/16/2007
7138119Compositions and methods for inhibition of HIV-1 infection
This invention provides a composition which comprises an admixture of three compounds, wherein: (a) one compound is an antibody which binds to a CCR5 receptor; (b) one compound retards attachment of HIV-1 to a CD4+ cell by retarding binding of HIV-1 gp120 envelope g...
11/21/2006
7138776Method and apparatus for controlling brushless DC motors in implantable medical devices
Methods and apparatus for controlling a polyphase motor in implantable medical device applications are provided. In one embodiment, the polyphase motor is a brushless DC motor. The back emf of a selected phase of the motor is sampled while a drive voltage of the sel...
11/21/2006
7132096Antimicrobial activity of gemfibrozil
The present invention provides methods for inhibiting growth of a bacterium which consists essentially of contacting the bacterium with gemfibrozil, or a related compound, in a concentration effective to inhibit growth of the bacterium. This invention also provides ...
11/07/2006
7128802Manufacturing method of compressible printing layer and manufacturing method of blanket for printing
The present invention provides a manufacturing method of a compressible printing layer, comprising a vulcanizing step comprising a first heating process in which one surface of a compressible printing layer including an unvulcanized compressible layer containing mic...
10/31/2006
7127144Optical fiber composite power cable having loose-tube-type optical fiber impregnated therein
Disclosed is an optical fiber composite power cable having a loose-tube-type optical fiber impregnated therein, wherein the optical fibers are installed in a loose tube made of metal to prevent lateral pressure from being imposed on the optical fibers by the metal c...
10/24/2006
7125956Compounds which prevent neuronal cell death and uses thereof
The present invention provides for a compound having the structure: (AA1)n-Cys-(AA2)m wherein n=0,1,2,3,4 or 5 and m=0,1,2,3,4 or 5, provided the sum of (n+m) is greater than or equal to two and less than or equal to five,...
10/24/2006
7125675Method for inhibiting tumor invasion or spreading in a subject
The present invention provides for a method for inhibiting tumor invasion or metastasis in a subject which comprises administering to the subject a therapeutically effective amount of a form of soluble Receptor for Advanced Glycation Endproducts (RAGE). The present ...
10/24/2006
7125658Small protein that interacts with a ribonucleotide reductase subunit and uses thereof
The present invention provides for an isolated Sml1 protein or a homologue thereof. The present invention also provides for a screening assay for identifying compounds that are capable of reducing the division rate of a cell by altering an interaction between a ribo...
10/24/2006
7122178Mesenchymal precursor cell
A method of enriching mesenchymal precursor sells including the step of enriching for cells based on at least two markers. The markers may be either i) the presence of markers specific for mesenchymal precursor cells, ii) the absence of markers specific for differen...
10/17/2006
7122307High throughput biological heart rate monitor that is molecularly determined
This invention provides for a chamber and system designed for use in assaying drug effects on heart rate. The chamber consists of a series of wells. Cardiac myocytes disaggregated from neonatal animals are plated onto the bottom of each well and grown under standard...
10/17/2006
7122185Anti-CCR5 antibody
The invention is directed an anti-CCR5 antibody which comprises (i) two light chains, each light chain comprising the expression product of a plasmid designated pVK:HuPRO140-VK (ATCC Deposit Designation PTA-4097), and (ii) two heavy chains, each heavy chain comprisi...
10/17/2006
7118859Methods for inhibiting HIV-1 infection
This invention provides an antibody capable of specifically inhibiting the fusion of an HIV-1 envelope glycoprotein+ cell with an appropriate CD4+ cell without cross reacting with the HIV-1 envelope glycoprotein or CD4 and capable of inhibiting...
10/10/2006
7116050Metal halide lamp, headlight apparatus for vehicle using the same, and method of manufacturing metal halide lamp
A metal halide lamp comprises a discharge container including a discharge space and a pair of sealing sections. A discharge medium containing a metal halide and a rare gas and essentially free from mercury is sealed in the discharge container. A pair of electrodes a...
10/03/2006
7115268Peptides useful for reducing symptoms of toxic shock syndrome and septic shock
This invention relates to compositions and methods which provide protection against, or reduce the severity of toxic shock and septic shock from bacterial infections. More particularly it relates to peptides derived from homologous sequences of the family of staphyl...
10/03/2006
7105149Isolation of five novel genes coding for new Fc receptors-type melanoma involved in the pathogenesis of lymphoma/myeloma
This invention provides an isolated nucleic acid molecule which encodes immunoglobulin receptor, Immunoglobulin superfamily Receptor Translocation Associated, IRTA, protein. Provided too, are the IRTA proteins encoded by the isolated nucleic acid molecules, IRTA1, I...
09/12/2006
7102083Jointing structure and jointing method for superconducting cable
An intermediate jointing structure having excellent mechanical and electrical characteristics and method of preparing the same. The intermediate jointing structure includes a metal pipe and a jointing sleeve. The metal pipe is inserted between a pair of superconduct...
09/05/2006
7101838Method to prevent accelerated atherosclerosis using (sRAGE) soluble receptor for advanced glycation endproducts
The present invention provides for a method to prevent accelerated atherosclerosis in a subject predisposed thereto which comprises administering to the subject a polypeptide derived from soluble receptor for advanced glycation endproduct in an amount effective to p...
09/05/2006
7094805Total synthesis of merrilactone A
This invention provides a total synthesis of Merrillactone and Merrilactone analogues for use as neurotrophic agents in the treatment of neurodegenerative diseases. The invention also provides intermediates for use in the synthesis of Merrilactone and its analogues....
08/22/2006
7094401HCV core protein binding agents for treatment of hepatitis C virus infection
The present invention provides a method of treating or preventing hepatitis C virus infection in a subject which comprises administering an effective amount of an agent to the subject, wherein the agent is capable of specifically binding to the HCV core protein so a...
08/22/2006
7087722Fibrin binding domain polypeptides and uses and methods of producing same
This invention provides an imaging agent which comprises a polypeptide labeled with an imageable marker, such polypeptide having an amino acid sequence substantially present in the fibrin binding domain of naturally-occurring human fibronectin and being capable of b...
08/08/2006
7083918Bacterial small-molecule three-hybrid system
A transgenic bacterial cell comprising (a) a dimeric small molecule which comprises a first moiety known to bind a first receptor domain covalently linked to a second moiety known to bind a second receptor domain; ...
08/01/2006
7081241Extracellular rage binding protein (EN-RAGE) and uses thereof
The present invention provides for an isolated human EN-RAGE peptide. The present invention also provides for a method for determining whether a compound is capable of inhibiting the interaction of an EN-RAGE peptide with a RAGE peptide, which comprises: (a) admixin...
07/25/2006
7081446Long-acting follicle stimulating hormone analogues and uses thereof
This invention provides FSH analogues having increased serum half-life relative to FSH. This invention also provides related compositions and methods for increasing fertility, egg production and spermatogenesis in a subject. ...
07/25/2006
7074580Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
The present invention provides processes for determining the molecular weight of glatiramer acetate and other copolymers using molecular weight markers. The present invention further provides a plurality of molecular weight markers for determining the molecular weig...
07/11/2006
7074597Multiplex genotyping using solid phase capturable dideoxynucleotides and mass spectrometry
This invention provides methods for detecting single nucleotide polymorphisms and multiplex genotyping using dideoxynucleotides and mass spectrometry. ...
07/11/2006
7074621Surface plasmon resonance biosensor for measurement of anti-glycolipid antibody levels in neuropathy
The present invention provides a method of detecting human antibodies in a sera solution. The invention also provides a method of quantitating anti-glycolipid antibody levels in solutions. The invention provides a method of diagnosing disease states, including neuro...
07/11/2006
7074769Oligonucleotide inhibitors of bcl-xL
This invention provides an antisense oligonucleotide or analog thereof comprising 10 or more contiguous bases or base analogs from the sequence of bases of sequence A, B, C, D, E, F, G, H, I, J, K, L, or M of FIG. 1. This invention also provides the above-des...
07/11/2006
7074915Antisense oligonucleotide against human acetylcholinesterase (AChE) and uses thereof
The invention relates to an antisense oligonucleotide targeted to the coding region of the human acetylcholinesterase (AChE), which selectively suppresses the AChE-R isoform of the enzyme. The antisense oligonucleotide is intended for use in the treatment and/or pre...
07/11/2006
7074771Gene encoding MNR2 and uses thereof
This invention provides an isolated nucleic acid molecule encoding a motor neuron restricted pattern, MNR2, protein. This invention provides an isolated nucleic acid molecule of at least 15 contiguous nucleotides capable of specifically hybridizing with a unique seq...
07/11/2006
7070991Cells expressing a CD4-IgG2 chimeric heterotetramer
This invention provides an expression vector encoding a CD4-gamma2 chimeric heavy chain homodimer. This invention also provides an expression vector encoding the heavy chains of a CD4-IgG2 chimeric heterotetramer. Finally, this invention provides an expression vecto...
07/04/2006
7070783Small molecular weight TNF receptor multimeric molecule
The present invention relates to a receptor molecule which binds to TNF comprising all or a functional portion of the extracellular domain (ECD) of two or more TNF-Rs linked via one or more polypeptide linkers. The receptor can further comprise a signal peptide of a...
07/04/2006
7067486Acetylcholinesterase-derived peptides and uses thereof
The invention relates to a cell growth and/or differentiation regulatory peptide comprising a sequence of about 9 to about 150 amino acids derived from acetylcholinesterase amino acid sequence, preferably from the C-terminal region of acetylcholinesterase. The inven...
06/27/2006
7063974Baroduric bacterium from Indian Ocean
Accordingly the present invention provides a process for the preparation an alcoholic extract with Carotenoids, UV absorption, antibacterial and pH indicating properties from a deep-sea bacterium which comprises a method for growing the cells in a medium with salini...
06/20/2006
7064122Pancreatic lipase inhibitor compounds, their synthesis and use
The subject invention features compounds having the structure: wherein X is O, S, CH2 or NR5; Y is O or S; R1 is H, substituted or unsubstituted C1-C15 alkyl, C
06/20/2006
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