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| Number | Title | Issue Date |
| 6973338 | Conjunctival monitor A method for monitoring blood/tissue gases, blood pH, and other elements of blood and tissue chemistry is described that uses a sensor tip that is placed adjacent to the conjunctiva of a patient to be monitored. Monitors and sensor using optical fiber sensors for pe... | 12/06/2005 |
| 6967250 | Energy transfer dyes Energy transfer dyes, their preparation, and their use as labels in biological systems is disclosed. The dyes are preferably in the form of cassettes which enable their attachment to a variety of biological materials. The dyes and the reagents that can be made from ... | 11/22/2005 |
| 6964844 | Hybrid phthalocyanine derivatives and their uses Water soluble hybrid phthalocyanine derivatives useful in competitive and noncompetitive assays immunoassays, nucleic acid and assays are disclosed and claimed having (1) at least one donor subunit with a desired excitation peak; and (2) at least one acceptor subuni... | 11/15/2005 |
| 6791480 | Method of preventing and/or alleviating repetitive use injury to electronic computer keyboard operator An electronic computer keyboard is constructed to provide the minimum keystroke resistance sufficient to prevent accidental switch closures otherwise resulting from the weight of the operator's fingers resting on the keys. This forces the operator to move his or her... | 09/14/2004 |
| 6777190 | Crosstalk inhibitors and their uses Assay for detecting the amount or presence of target ligand in a sample. The assay includes a ligand analogue conjugate having a linkage site and a binding site, a ligand receptor, and a sample. The assay includes the steps of providing at least one crosstalk inhibi... | 08/17/2004 |
| 6747060 | Non-natural galanin receptor ligands Compounds which are non-natural galanin receptor ligands are disclosed. The ligands are of small size, have agonist or antagonist galanin activity and may cross the blood-brain barrier to displace galanin from galanin receptors. The ligands are useful as medicaments... | 06/08/2004 |
| 6727354 | Compositions and methods for TIGR genotyping assays Methods and compositions are described for use in the rapid and simultaneous screening of one or more samples for one or more polymorphisms in the TIGR gene. The methods and compositions of the present invention can be used to rapidly determine if polymorphisms in a... | 04/27/2004 |
| 6720144 | Detection of clonal T-cell receptor-γ gene rearrangement by PCR/temporal temperature gradient gel electrophoresis (TTGE) The present invention provides methods and compositions for detecting and analyzing clonal T-cell receptor (TCR) gene rearrangement using temporal temperature gradient gel electrophoresis (TTGE), which employs a gradual and uniform increase in the temperature of a c... | 04/13/2004 |
| 6710088 | Inorganic ion receptor-active compounds The present invention features compounds able to modulate one or more activities of an inorganic ion receptor and methods for treating diseases or disorders using such compounds. Preferred compounds can mimic or block the effect of extracellular calcium on a cell su... | 03/23/2004 |
| 6700037 | Method of cloning porcine animals The present invention relates to materials and methods for cloning porcine animals. The invention relates in part to totipotent cells useful for cloning porcine animals, porcine embryos produced from such cells by employing nuclear transfer techniques, an... | 03/02/2004 |
| 6683189 | Method for the synthesis of pyrrole and imidazole carboxamides on a solid support The present invention describes a novel method for the solid phase synthesis of polyamides containing imidazole and pyrrole carboxamides. The polyamides are prepared on a solid support from aromatic carboxylic acids and aromatic amines with high stepwise ... | 01/27/2004 |
| 6670196 | Rapid evaluation of the ratio of biological molecules The invention relates in part to novel methods of rapidly determining the ratio of biological molecules. The invention also relates in part to a kit for rapidly determining the ratio of biological molecules.... | 12/30/2003 |
| 6669907 | Devices comprising multiple capillarity inducing surfaces Assay device structures for a device where fluid flows from a one region to another. The device structures comprising one or more capillarity-inducing structures; where the capillarity-inducing structure induces capillary force along an axis that is essen... | 12/30/2003 |
| 6656428 | Automated point of care detection system including complete sample processing capabilities The present invention relates to cost effective analytical instruments for determining the presence or amount of an analyte in a sample. The analytical instruments utilize an assay cartridge which has a sample receiving port and a rotatable carousel conta... | 12/02/2003 |
| 6635417 | Complex formation between DSDNA and oligomer of cyclic heterocycles Methods and compositions are provided for forming complexes between dsDNA and oligomers of heterocycles, aliphatic amino acids, particularly omega-amino acids, and a polar end group. By appropriate choice of target sequences and composition of the oligome... | 10/21/2003 |
| 6603059 | Method of cloning animals The present invention relates to cloning technologies. The invention relates in part to immortalized and totipotent cells useful for cloning animals, the embryos produced from these cells using nuclear transfer techniques, animals that arise from these ce... | 08/05/2003 |
| 6601006 | Methods for the calibration of analyte assays The present invention provides methods for the calibration of detection and/or quantification assays for a wide variety of analytes in wet or dry chemistry assay systems. The invention involves the use of a reagent and calibrator, which provide a detectab... | 07/29/2003 |
| 6534289 | Nucleic acids encoding mGLuR/CaR chimera The present invention provides chimeric receptors. The chimeric receptors comprise at least one region homologous to a region of a metabotropic glutamate receptor and at least one region homologous to a region of a calcium receptor. The invention also inc... | 03/18/2003 |
| 6432656 | Calcilytic compounds The present invention features calcilytic compounds. "calcilytic compounds" refer to compounds able to inhibit calcium receptor activity. Also described are the use of calcilytic compounds to inhibit calcium receptor activity and/or achieve a beneficial e... | 08/13/2002 |
| 6362231 | Calcium receptor active compounds A novel calcium receptor active compound having the formula is provided: Ar1 --[CR1 R2 ]P --X--[CR3 R4 ]q --[CR5 R6 ]--NR7 --[CR8 R9 ... | 03/26/2002 |
| 6342532 | Inorganic ion receptor active compounds The present invention features compounds able to modulate one or more activities of an inorganic ion receptor and methods for treating diseases or disorders using such compounds. Preferred compounds can mimic or block the effect of extracellular calcium o... | 01/29/2002 |
| 6306912 | Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases Method for identifying a compound useful for the therapeutic treatment of a neurological disease or disorder such as stroke, head trauma, spinal cord injury, epilepsy, anxiety, or neurodegenerative diseases such as Alzheimer's Disease, Huntington's Diseas... | 10/23/2001 |
| 4683782 | Microcentrifuge tube opener A microcentrifuge tube opener adapted to open a microcentrifuge tube comprising a container with an opening, and a lid for the container, the lid having a lip projection extending past the outer perimeter of the opening and an inner portion shaped to seal... | 08/04/1987 |
