...that the video game, Pong, was invented by a guy who graduated at the bottom of his engineering class? Nolan Bushnell spent more time running the games at a local amusement park than he did on his studies at the University of Utah. His dreams of working for Disney's amusement empire were dashed when the company wouldn't hire him. Taking a boring job, Nolan daydreamed about electronic versions of popular games. He invented Pong, the first video game, and went on to found Atari Co.
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| Number | Title | Issue Date |
| 8039690 | Stress-regulated genes of plants, transgenic plants containing same, and methods of use Clusters of plant genes that are regulated in response to one or more stress conditions are provided, as are isolated plant stress-regulated genes, including portions thereof comprising a coding sequence or a regulatory element, and to consensus sequences comprising... | 10/18/2011 |
| 7985841 | Heterodimeric receptor libraries using phagemids Filamentous phage comprising a matrix of cpVIII proteins encapsulating a genome encoding first and second polypeptides of an antogenously assembling receptor, such as an antibody, and a receptor comprised of the first and second polypeptides surface-integrated into ... | 07/26/2011 |
| 7863241 | Compositions for treatment and prevention of pulmonary conditions The invention provides compositions and methods for treating pulmonary conditions and for reducing the negative effects of pulmonary inflammation. Such compositions and methods employ protease inhibitors and a lung surfactant mixture. The compositions and methods ca... | 01/04/2011 |
| 7807817 | Enzymatic nucleic acid molecules The present invention discloses nucleic acid enzymes and deoxyribonucleic acid enzymes capable of cleaving nucleic acid sequences or molecules, particularly RNA, in a site-specific manner, as well as compositions including same. Methods of making and using the discl... | 10/05/2010 |
| 7732150 | Lambdoid bacteriophage vectors for expression of foreign proteins Lambdoid phage comprising a matrix of proteins encapsulating a genome encoding first and second polypeptides of an autogenously assembling receptor and a receptor comprised of the first and second polypeptides surface-integrated into the matrix via a lambdoid phage ... | 06/08/2010 |
| 7705199 | Compositions and methods for treatment of autoimmune and related diseases Compositions and methods are provided for treatment of autoimmune and other related diseases. 3d, a point mutation of the protein uncoordinated-93b (unc-93B), unc-93A, unc-93B, and unc-93C, polypeptides, nucleic acids encoding them and methods for making and using t... | 04/27/2010 |
| 7692065 | Stress-regulated genes of plants, transgenic plants containing same, and methods of use Clusters of plant genes that are regulated in response to one or more stress conditions are provided, as are isolated plant stress-regulated genes, including portions thereof comprising a coding sequence or a regulatory element, and to consensus sequences comprising... | 04/06/2010 |
| 7601885 | Transgenic plant comprising a cassava vein mosaic virus promoter and a heterologous nucleic acid sequence The invention relates to compositions and methods useful for the production of transgenic plants. In particular, the invention relates to cassava vein mosaic virus (CsVMV) promoter sequences and expression cassettes containing CsVMV promoter sequences. The invention... | 10/13/2009 |
| 7595051 | Methods of treating neovascular glaucoma, macular degeneration and capillary proliferation with alphavbeta3-specific antibodies The present invention describes methods for inhibition angiogenesis in tissues using vitronectin αvβ3 antagonists, and particularly for inhibiting angiogenesis in inflamed tissues and in tumor tissues and metastases using therapeutic composit... | 09/29/2009 |
| 7482007 | Methods of inhibiting angiogenesis to treat cancer with alphavbeta3-specific antibodies The present invention describes methods for inhibition angiogenesis in tissues using vitronectin αvβ3 antagonists, and particularly for inhibiting angiogenesis in inflamed tissues and in tumor tissues and metastases using therapeutic composit... | 01/27/2009 |
| 7473424 | Anti-dengue virus antibodies and compositions The present invention relates to at least one novel anti-Dengue virus antibody, including isolated nucleic acids that encode at least one anti-Dengue virus antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, includin... | 01/06/2009 |
| 7439335 | MHC class II antigen-presenting systems and methods for activating CD4T cells The present invention relates to synthetic antigen-presenting matrices, their methods of making and their methods of use. One such matrix is cells that have been transfected to produce MHC antigen-presenting molecules with one or more accessory molecules. The matric... | 10/21/2008 |
| 7402314 | In vivo activation of tumor-specific cytotoxic T cells The present invention relates to methods and compositions of activating cytotoxic T lymphocytes (CTLs) in vivo with specificity for particular antigenic peptides, and to methods and compositions of using activated CTLs in vivo for the treatment of a variety of disea... | 07/22/2008 |
| 7402430 | MHC class II antigen-presenting systems and methods for activating CD4T cells The present invention relates to synthetic antigen-presenting matrices, their methods of making and their methods of use. One such matrix is cells that have been transfected to produce MHC antigen-presenting molecules with one or more accessory molecules. The matric... | 07/22/2008 |
| 7399743 | Targeted thrombosis The invention provided compositions and methods to initiate site-specific thrombosis in tumor vasculature. The present invention also provides methods for using the disclosed compositions and methods to treat tumors. ... | 07/15/2008 |
| 7354586 | Methods of treating arthritis and diabetic retinopathy with αβ-specific antibodies The present invention describes methods for inhibition angiogenesis in tissues using vitronectin αvβ3 antagonists, and particularly for inhibiting angiogenesis in inflamed tissues and in tumor tissues and metastases using therapeutic composit... | 04/08/2008 |
| 7351874 | Mouse model for fatty acid amide-related neurobehaviors The invention relates to an animal model for studying behavior related to fatty acid amide and hydrolysis of fatty acid amide. The invention provides transgenic animals in which the protein fatty acid amide hydrolase is not expressed, and methods of using such anima... | 04/01/2008 |
| 7348173 | Fatty-acid amide hydrolase The soporific activity of cis-9,10-octadecenoamide and other soporific fatty acid primary amides is neutralized by hydrolysis in the presence of fatty-acid amide hydrolase (FAAH). Hydrolysis of cis-9,10-octadecenoamide by FAAH leads to the formation of oleic acid, a... | 03/25/2008 |
| 7329406 | Methods of treating psoriasis with αβ-specific antibodies The present invention describes methods for inhibition angiogenesis in tissues using vitronectin αvβ3 antagonists, and particularly for inhibiting angiogenesis in inflamed tissues and in tumor tissues and metastases using therapeutic composit... | 02/12/2008 |
| 7326569 | Hybrid cells producing monoclonal anti-CD14 antibodies This invention provides hybridoma cell lines producing monoclonal antibodies which inhibit CD14 mediated cell activation. Monoclonal antibodies produced by these cell lines also are provided. The antibodies are useful for the detection of the presence of cell surfac... | 02/05/2008 |
| 7291473 | Screening process for atopic dermatitis The present invention provides a process of screening patients for atopic dermatitis. The process includes the step of determining, in sera of the patient, the presence of antibodies against nuclear antigens such as transcription co-activator p75, wherein the presen... | 11/06/2007 |
| 7115414 | Vanilloid receptor-related nucleic acids and polypeptides This invention provides novel genes and polypeptides of the VR family, identification of trkA+ pain specific genes expressed in the DRG, and use of these genes and polypeptides for the treatment of pain and identification of agents useful in the treatment... | 10/03/2006 |
| 6884410 | Methods for modulating antigen-specific immune responses Interleukin-10 for producing a population of cells which are capable of inhibiting or suppressing reactions to alloantigens, for example in graft-versus-host disease or tissue rejection, is described. Interleukin-10 for reducing responses in mixed lymphocyte respons... | 04/26/2005 |
| 6709872 | Method and apparatus for dispensing low nanoliter volumes of liquid while minimizing waste There is provided a method and apparatus for aspirating a volume of liquid into a syringe from a sample of the liquid. A substantial portion of the liquid in the syringe is subsequently dispensed from the syringe and returned to the sample. Accordingly, a small port... | 03/23/2004 |