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Patent No. 5356330

Apparatus for Simulating a High Five

A self-righting hand-arm configuration which is adapted to pivot when struck by a user, thereby simulating a "high five."

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Attorney: Wallen, III; John W.


Number of patents: 56
Last date: May 15, 2012

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NumberTitleIssue Date
8178494Modified human growth hormone formulations with an increased serum half-life
Formulations of modified growth hormone polypeptides are provided, including human growth hormone polypeptides with one or more non-naturally encoded amino acids with an increased half-life. ...
05/15/2012
8178108Methods for expression and purification of recombinant human growth hormone
The present invention relates generally to the production, purification, and isolation of human growth hormone (hGH). More particularly, the invention relates to the production, purification, and isolation of substantially purified hGH comprising non-naturally encod...
05/15/2012
8163695Formulations of human growth hormone comprising a non-naturally encoded amino acid
Formulations of modified human growth hormone polypeptides are provided. ...
04/24/2012
8143216Modified human growth hormone
Modified growth hormone polypeptide and uses thereof are provided. ...
03/27/2012
8119603Modified human interferon polypeptides and their uses
Modified human interferon polypeptides and uses thereof are provided. ...
02/21/2012
8093356Pegylated human interferon polypeptides
Modified human interferon polypeptides and uses thereof are provided, including PEGylated human interferon polypeptides with one or more non-naturally encoded amino acids. ...
01/10/2012
8080391Process of producing non-naturally encoded amino acid containing high conjugated to a water soluble polymer
The present invention relates generally to the production, purification, and isolation of human growth hormone (hGH). More particularly, the invention relates to the production, purification, and isolation of substantially purified hGH from recombinant host cells or...
12/20/2011
8053560Modified human plasma polypeptide or Fc scaffolds and their uses
Modified human plasma polypeptides or Fc and uses thereof are provided. ...
11/08/2011
8022186Modified human plasma polypeptide or Fc scaffolds and their uses
Modified human plasma polypeptides or Fc and uses thereof are provided. ...
09/20/2011
8012931Modified FGF-21 polypeptides and their uses
Modified FGF-21 polypeptides and uses thereof are provided. ...
09/06/2011
8008428Azide- or acetylene-terminated poly(alkylene oxide, oxyethylated polyol or olefinic Alcohol)
The invention provides water-soluble compounds that include a polymer and at least one terminal azide or acetylene moiety. Also provided are highly efficient methods for the selective modification of proteins with PEG derivatives, which involves the selective incorp...
08/30/2011
7959926Methods for expression and purification of recombinant human growth hormone mutants
The present invention relates generally to the production, purification, and isolation of human growth hormone (hGH). More particularly, the invention relates to the production, purification, and isolation of substantially purified hGH comprising non-naturally encod...
06/14/2011
7947473Methods for expression and purification of pegylated recombinant human growth hormone containing a non-naturally encoded keto amino acid
The present invention relates generally to the production, purification, and isolation of human growth hormone (hGH). More particularly, the invention relates to the production, purification, and isolation of substantially purified hGH comprising non-naturally encod...
05/24/2011
7939496Modified human growth horomone polypeptides and their uses
Modified growth hormone polypeptide and uses thereof are provided. ...
05/10/2011
7919591Modified human plasma polypeptide or Fc scaffolds and their uses
Modified human plasma polypeptides or Fc and uses thereof are provided. ...
04/05/2011
7883866Compositions of aminoacyl-tRNA synthetase and uses thereof
Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNA's/synthetases are provided. Methods for identifying these orthogonal pairs are also...
02/08/2011
7846689Compositions of aminoacyl-tRNA synthetase and uses thereof
Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNA's/synthetases are provided. Methods for identifying these orthogonal pairs are also...
12/07/2010
7858344Compositions of aminoacyl-tRNA synthetase and uses thereof
Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNA's/synthetases are provided. Methods for identifying these orthogonal pairs are also...
12/28/2010
7838265Compositions of aminoacyl-tRNA synthetase and uses thereof
Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNA's/synthetases are provided. Methods for identifying these orthogonal pairs are also...
11/23/2010
7829310Compositions of aminoacyl-tRNA synthetase and uses thereof
Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNA's/synthetases are provided. Methods for identifying these orthogonal pairs are also...
11/09/2010
7820766Branched acetylene-containing poly(alkylene oxides, oxyethylated polyols or olefinic alcohols)
The invention provides water-soluble compounds that include a polymer and at least one terminal azide or acetylene moiety. Also provided are highly efficient methods for the selective modification of proteins with PEG derivatives, which involves the selective incorp...
10/26/2010
7816320Formulations of human growth hormone comprising a non-naturally encoded amino acid at position 35
Formulations of modified human growth hormone polypeptides are provided. ...
10/19/2010
7737226Acetylene group-containing poly(alkylene oxide, oxyethylated polyol or olefinic alcohol)
The invention provides water-soluble compounds that include a polymer and at least one terminal azide or acetylene moiety. Also provided are highly efficient methods for the selective modification of proteins with PEG derivatives, which involves the selective incorp...
06/15/2010
7736872Compositions of aminoacyl-TRNA synthetase and uses thereof
Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNA's/synthetases are provided. Methods for identifying these orthogonal pairs are also...
06/15/2010
7638299Biosynthetic polypeptides utilizing non-naturally encoded amino acids
Modified biosynthetic polypeptide molecules, methods for manufacturing, and uses thereof are provided. ...
12/29/2009
7632924Antigen-binding polypeptides and their uses
Novel antigen-binding polypeptides (ABP) and uses thereof are provided. ...
12/15/2009
7632823Compositions of tRNA and uses thereof
Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNA's/synthetases are provided. Methods for identifying these orthogonal pairs are also...
12/15/2009
7230068Polymer derivatives
The invention provides water-soluble compounds that include a polymer and at least one terminal azide or acetylene moiety. Also provided are highly efficient methods for the selective modification of proteins with PEG derivatives, which involves the selective incorp...
06/12/2007
6673792Broad-spectrum anti-emetic compositions and associated methods
Broad-spectrum anti-emetic pharmaceutical compositions are disclosed. The discloses broad-spectrum ant-emetics disclosed herein comprise selected neuroreceptor antagonists specifically formulated to treat and prevent to most common forms of emesis. In one...
01/06/2004
6629454Tire pressure monitoring device
A low tire pressure monitoring device that is affixed to a tire valve stem and methods of using the same. The monitoring device comprises a housing having a counter-pressure chamber, a main pressure chamber, and a flexible membrane that separates the two ...
10/07/2003
6548270DNA encoding human acid-sensing ion channel BNaC4 (ASIC4)
DNA encoding human acid sensing ion channel BnaC4 has been cloned and characterized. The recombinant protein is capable of forming biologically active protein. The cDNA's have been expressed in recombinant host cells that produce active recombinant protei...
04/15/2003
6485957DNA encoding the human serine protease EOS
Here we describe the molecular identification of a cDNA encoding a novel serine protease we have termed protease EOS. The deduced amino acid sequence, and it alignment with other well-characterized serine proteases indicates that it is a member of the S1 ...
11/26/2002
6458552Metalloprotease peptide substrates and methods
The present invention describes peptide substrates of the metalloproteases, ADAM8, ADAM15 and MDC-L. The invention also describes methods using these peptides to discover pharmaceutical agents that modulate these proteases. The invention further describes...
10/01/2002
6458564DNA encoding the human serine protease T
Here we describe the molecular identification of a cDNA encoding a novel serine protease we have termed protease T. The deduced amino acid sequence encodes a prepro form of 290 amino acids, and its alignment with other well-characterized serine proteases ...
10/01/2002
6455278DNA encoding human vanilloid receptor VR3
DNA encoding human VR1 receptor has been cloned and characterized. The recombinant protein is capable of forming biologically active protein. The cDNA's have been expressed in recombinant host cells that produce active recombinant protein. The recombinant...
09/24/2002
6437100DNA encoding a human histamine receptor of the H3 subtype
DNAs encoding the human histamine H3 receptor have been cloned and characterized. The recombinant protein is capable of forming biologically active histamine H3 receptor protein. The cDNA's have been expressed in recombinant host cells which produce activ...
08/20/2002
6413743DNA encoding a human histamine receptor of the H3 subtype
DNAs encoding the human histamine H3 receptor have been cloned and characterized. The recombinant protein is capable of forming biologically active histamine H3 receptor protein. The cDNA's have been expressed in recombinant host cells which produce activ...
07/02/2002
6365370DNA encoding a human subunit 5-HT3-C of the 5-HT3 serotonin receptor
DNA encoding human 5-HT3-C has been cloned and characterized. The recombinant protein is capable of forming biologically active human 5-HT3-C protein. The cDNA has been expressed in recombinant host cells that produce active recombinant protein. In additi...
04/02/2002
6310078Substituted amino acids as erythropoietin mimetics
This invention relates to a series of substituted amino acids of Formula I ##STR1## pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention are small molecules which bind to the erythropoieti...
10/30/2001
6306911Substituted amino acids as neutral sphingomyelinase inhibitors
This invention relates to a series of substituted amino acids of Formula I ##STR1## pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention are small molecules that bind to neutral sphingomye...
10/23/2001
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