Apparatus for Simulating a High Five
A self-righting hand-arm configuration which is adapted to pivot when struck by a user, thereby simulating a "high five."
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| Number | Title | Issue Date |
| 8178494 | Modified human growth hormone formulations with an increased serum half-life Formulations of modified growth hormone polypeptides are provided, including human growth hormone polypeptides with one or more non-naturally encoded amino acids with an increased half-life. ... | 05/15/2012 |
| 8178108 | Methods for expression and purification of recombinant human growth hormone The present invention relates generally to the production, purification, and isolation of human growth hormone (hGH). More particularly, the invention relates to the production, purification, and isolation of substantially purified hGH comprising non-naturally encod... | 05/15/2012 |
| 8163695 | Formulations of human growth hormone comprising a non-naturally encoded amino acid Formulations of modified human growth hormone polypeptides are provided. ... | 04/24/2012 |
| 8143216 | Modified human growth hormone Modified growth hormone polypeptide and uses thereof are provided. ... | 03/27/2012 |
| 8119603 | Modified human interferon polypeptides and their uses Modified human interferon polypeptides and uses thereof are provided. ... | 02/21/2012 |
| 8093356 | Pegylated human interferon polypeptides Modified human interferon polypeptides and uses thereof are provided, including PEGylated human interferon polypeptides with one or more non-naturally encoded amino acids. ... | 01/10/2012 |
| 8080391 | Process of producing non-naturally encoded amino acid containing high conjugated to a water soluble polymer The present invention relates generally to the production, purification, and isolation of human growth hormone (hGH). More particularly, the invention relates to the production, purification, and isolation of substantially purified hGH from recombinant host cells or... | 12/20/2011 |
| 8053560 | Modified human plasma polypeptide or Fc scaffolds and their uses Modified human plasma polypeptides or Fc and uses thereof are provided. ... | 11/08/2011 |
| 8022186 | Modified human plasma polypeptide or Fc scaffolds and their uses Modified human plasma polypeptides or Fc and uses thereof are provided. ... | 09/20/2011 |
| 8012931 | Modified FGF-21 polypeptides and their uses Modified FGF-21 polypeptides and uses thereof are provided. ... | 09/06/2011 |
| 8008428 | Azide- or acetylene-terminated poly(alkylene oxide, oxyethylated polyol or olefinic Alcohol) The invention provides water-soluble compounds that include a polymer and at least one terminal azide or acetylene moiety. Also provided are highly efficient methods for the selective modification of proteins with PEG derivatives, which involves the selective incorp... | 08/30/2011 |
| 7959926 | Methods for expression and purification of recombinant human growth hormone mutants The present invention relates generally to the production, purification, and isolation of human growth hormone (hGH). More particularly, the invention relates to the production, purification, and isolation of substantially purified hGH comprising non-naturally encod... | 06/14/2011 |
| 7947473 | Methods for expression and purification of pegylated recombinant human growth hormone containing a non-naturally encoded keto amino acid The present invention relates generally to the production, purification, and isolation of human growth hormone (hGH). More particularly, the invention relates to the production, purification, and isolation of substantially purified hGH comprising non-naturally encod... | 05/24/2011 |
| 7939496 | Modified human growth horomone polypeptides and their uses Modified growth hormone polypeptide and uses thereof are provided. ... | 05/10/2011 |
| 7919591 | Modified human plasma polypeptide or Fc scaffolds and their uses Modified human plasma polypeptides or Fc and uses thereof are provided. ... | 04/05/2011 |
| 7883866 | Compositions of aminoacyl-tRNA synthetase and uses thereof Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNA's/synthetases are provided. Methods for identifying these orthogonal pairs are also... | 02/08/2011 |
| 7846689 | Compositions of aminoacyl-tRNA synthetase and uses thereof Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNA's/synthetases are provided. Methods for identifying these orthogonal pairs are also... | 12/07/2010 |
| 7858344 | Compositions of aminoacyl-tRNA synthetase and uses thereof Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNA's/synthetases are provided. Methods for identifying these orthogonal pairs are also... | 12/28/2010 |
| 7838265 | Compositions of aminoacyl-tRNA synthetase and uses thereof Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNA's/synthetases are provided. Methods for identifying these orthogonal pairs are also... | 11/23/2010 |
| 7829310 | Compositions of aminoacyl-tRNA synthetase and uses thereof Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNA's/synthetases are provided. Methods for identifying these orthogonal pairs are also... | 11/09/2010 |
| 7820766 | Branched acetylene-containing poly(alkylene oxides, oxyethylated polyols or olefinic alcohols) The invention provides water-soluble compounds that include a polymer and at least one terminal azide or acetylene moiety. Also provided are highly efficient methods for the selective modification of proteins with PEG derivatives, which involves the selective incorp... | 10/26/2010 |
| 7816320 | Formulations of human growth hormone comprising a non-naturally encoded amino acid at position 35 Formulations of modified human growth hormone polypeptides are provided. ... | 10/19/2010 |
| 7737226 | Acetylene group-containing poly(alkylene oxide, oxyethylated polyol or olefinic alcohol) The invention provides water-soluble compounds that include a polymer and at least one terminal azide or acetylene moiety. Also provided are highly efficient methods for the selective modification of proteins with PEG derivatives, which involves the selective incorp... | 06/15/2010 |
| 7736872 | Compositions of aminoacyl-TRNA synthetase and uses thereof Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNA's/synthetases are provided. Methods for identifying these orthogonal pairs are also... | 06/15/2010 |
| 7638299 | Biosynthetic polypeptides utilizing non-naturally encoded amino acids Modified biosynthetic polypeptide molecules, methods for manufacturing, and uses thereof are provided. ... | 12/29/2009 |
| 7632924 | Antigen-binding polypeptides and their uses Novel antigen-binding polypeptides (ABP) and uses thereof are provided. ... | 12/15/2009 |
| 7632823 | Compositions of tRNA and uses thereof Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNA's/synthetases are provided. Methods for identifying these orthogonal pairs are also... | 12/15/2009 |
| 7230068 | Polymer derivatives The invention provides water-soluble compounds that include a polymer and at least one terminal azide or acetylene moiety. Also provided are highly efficient methods for the selective modification of proteins with PEG derivatives, which involves the selective incorp... | 06/12/2007 |
| 6673792 | Broad-spectrum anti-emetic compositions and associated methods Broad-spectrum anti-emetic pharmaceutical compositions are disclosed. The discloses broad-spectrum ant-emetics disclosed herein comprise selected neuroreceptor antagonists specifically formulated to treat and prevent to most common forms of emesis. In one... | 01/06/2004 |
| 6629454 | Tire pressure monitoring device A low tire pressure monitoring device that is affixed to a tire valve stem and methods of using the same. The monitoring device comprises a housing having a counter-pressure chamber, a main pressure chamber, and a flexible membrane that separates the two ... | 10/07/2003 |
| 6548270 | DNA encoding human acid-sensing ion channel BNaC4 (ASIC4) DNA encoding human acid sensing ion channel BnaC4 has been cloned and characterized. The recombinant protein is capable of forming biologically active protein. The cDNA's have been expressed in recombinant host cells that produce active recombinant protei... | 04/15/2003 |
| 6485957 | DNA encoding the human serine protease EOS Here we describe the molecular identification of a cDNA encoding a novel serine protease we have termed protease EOS. The deduced amino acid sequence, and it alignment with other well-characterized serine proteases indicates that it is a member of the S1 ... | 11/26/2002 |
| 6458552 | Metalloprotease peptide substrates and methods The present invention describes peptide substrates of the metalloproteases, ADAM8, ADAM15 and MDC-L. The invention also describes methods using these peptides to discover pharmaceutical agents that modulate these proteases. The invention further describes... | 10/01/2002 |
| 6458564 | DNA encoding the human serine protease T Here we describe the molecular identification of a cDNA encoding a novel serine protease we have termed protease T. The deduced amino acid sequence encodes a prepro form of 290 amino acids, and its alignment with other well-characterized serine proteases ... | 10/01/2002 |
| 6455278 | DNA encoding human vanilloid receptor VR3 DNA encoding human VR1 receptor has been cloned and characterized. The recombinant protein is capable of forming biologically active protein. The cDNA's have been expressed in recombinant host cells that produce active recombinant protein. The recombinant... | 09/24/2002 |
| 6437100 | DNA encoding a human histamine receptor of the H3 subtype DNAs encoding the human histamine H3 receptor have been cloned and characterized. The recombinant protein is capable of forming biologically active histamine H3 receptor protein. The cDNA's have been expressed in recombinant host cells which produce activ... | 08/20/2002 |
| 6413743 | DNA encoding a human histamine receptor of the H3 subtype DNAs encoding the human histamine H3 receptor have been cloned and characterized. The recombinant protein is capable of forming biologically active histamine H3 receptor protein. The cDNA's have been expressed in recombinant host cells which produce activ... | 07/02/2002 |
| 6365370 | DNA encoding a human subunit 5-HT3-C of the 5-HT3 serotonin receptor DNA encoding human 5-HT3-C has been cloned and characterized. The recombinant protein is capable of forming biologically active human 5-HT3-C protein. The cDNA has been expressed in recombinant host cells that produce active recombinant protein. In additi... | 04/02/2002 |
| 6310078 | Substituted amino acids as erythropoietin mimetics This invention relates to a series of substituted amino acids of Formula I ##STR1## pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention are small molecules which bind to the erythropoieti... | 10/30/2001 |
| 6306911 | Substituted amino acids as neutral sphingomyelinase inhibitors This invention relates to a series of substituted amino acids of Formula I ##STR1## pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention are small molecules that bind to neutral sphingomye... | 10/23/2001 |