Felix Hoffmann, a German chemist, was searching for something to relieve his father's arthritis. In doing so, he "rediscovered" acetylsalicylic acid and in 1900, patented a stable process for developing it. Hence, we have aspirin.
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| Number | Title | Issue Date |
| 8041515 | Use of impedance-based cytological profiling to classify cellular response profiles upon exposure to biologically active agents The present invention provides methods of multi-dimensional profiling of biologically active agents and determining their effects on biological systems. The methods of the present invention include real-time impedance monitoring of cellular responses to biologically... | 10/18/2011 |
| 8026080 | Real time electronic cell sensing system and applications for cell-based assays The present invention includes devices, systems, and methods for assaying cells using cell-substrate impedance monitoring. In one aspect, the invention provides cell-substrate impedance monitoring devices that comprise electrode arrays on a nonconducting substrate, ... | 09/27/2011 |
| 7998046 | Methods and devices for treating pathological conditions of the human knee A method for passive and active exercises of the human knee using an apparatus having a substantially rigid support member having two substantially similar sides joined at one end, which forms an apex, and having a third side including two opposing linear surfaces s... | 08/16/2011 |
| 7997054 | Fiber strand and implantable supporting body having a fiber strand The invention relates to a fiber strand (10) for an implantable supporting body (100) comprising at least two individual fibers (12). The at least two individual fibers (12) are each shorter in their longitudinal extent than the longitudi... | 08/16/2011 |
| 7943526 | Process for the wet-chemical treatment of one side of silicon wafers The present invention relates in general terms to the treatment or processing of substrate surfaces. In particular, the invention relates to processes for modifying the surface of silicon wafers. ... | 05/17/2011 |
| 7927630 | Use of autologous sediment from fluid aspirates as vehicles for drug delivery A method of using fluid aspirates as vehicles for drug delivery by collecting a fluid aspirate such as synovial joint effusion, pleural effusion, pericardial effusion, or ascites from a patient and centrifuging the fluid aspirate to provide a supernatant and a sedim... | 04/19/2011 |
| 7876108 | Real time electronic cell sensing system and applications for cytotoxicity profiling and compound assays The present invention includes devices, systems, and methods for assaying cells using cell-substrate impedance monitoring. In one aspect, the invention provides cell-substrate impedance monitoring devices that comprise electrode arrays on a nonconducting substrate, ... | 01/25/2011 |
| 7816080 | Identifying organisms by detecting intronic nucleic acid or encoded proteins The present invention provides novel methods for characterizing organisms by identifying the presence, absence, size or sequence polymorphism of intronic regions. The method involves selecting intronic regions from nuclear or organellar gene sequences that are usefu... | 10/19/2010 |
| 7785582 | Use of synovium and omentum for tissue engineering A method for treating a patient to repair or regenerate damaged tissues or organs in which synovium from a joint or omentum from the abdomen are harvested to provide explants, optionally separating cells from the synovium or omentum explants for culture or tissue sp... | 08/31/2010 |
| 7781197 | Transformed bryophyte cell having disrupted endogenous alpha 1,3-fucosyl and beta 1,2-xylosyl transferase encoding nucleotide sequences for the production of heterologous glycosylated proteins Bryophyte plants and bryophyte plant cells comprising dysfunctional fucT and xylT genes and an introduced glycosyltransferase gene, methods for the production of glycosylated proteins therewith, vectors and uses thereof. ... | 08/24/2010 |
| 7780915 | Fecal sample test device and methods of use The present invention includes devices and methods for the detection of an analyte in a fecal sample. The fecal sample test device includes a sample collection structure and sample collection housing, a detection housing, a fecal suspension solution or fecal dilutio... | 08/24/2010 |
| 7741539 | Transformed plant cell expressing five mammalian proteins involved in sialylation and a protein involved in galactosylation The present invention relates to a method for producing heterologous glycosylated proteins in non-animal eukaryotic cells such as in transformed bryophyte, yeast, ciliate or algae cells. In particular, the method relates to a method for producing glycosylated protei... | 06/22/2010 |
| 7741028 | Methods of identifying genetic markers in the human cystic fibrosis transmembrane conductance regulator (CFTR) gene The present invention relates to the field of genetic screening. More specifically, the described embodiments concern methods to screen multiple samples, in a single assay, for the presence or absence of mutations or polymorphisms in a plurality of genes. Approaches... | 06/22/2010 |
| 7736509 | Probiotic system and aquaculture devices An aquaculture or wastewater effluent water quality device to improve water quality and food supply in an aquaculture pond or body of water by incubating beneficial microbes in a temperature controlled environment and systematically releasing them to the surrounding... | 06/15/2010 |
| 7732127 | Dynamic monitoring of cell adhesion and spreading using the RT-CES system The present invention includes devices and methods for dynamically monitoring cell adhesion and cell spreading. Cells are added to a microelectronic cell sensor array operably connected to an impedance analyzer. The device also includes a coating including biologica... | 06/08/2010 |
| 7665424 | Harness interface conduit, tether line, and swivel for use in animals A harness for use in coupling with an animal interface, the animal interface comprising one or more of conduits for transmitting fluid, electrical signals, or optical signals. Swivel extension tether for quick connect to harness, dual-ended swivel, an extension line... | 02/23/2010 |
| 7563762 | Composition and process for stabilizing of biomolecules The present invention relates in general to the field of biotechnology. The invention particularly relates to a composition and process for stabilizing or preserving biological molecules, as well as devices that comprise correspondingly stabilized or preserved biomo... | 07/21/2009 |
| 7560269 | Real time electronic cell sensing system and applications for cytotoxicity profiling and compound assays The present invention includes devices, systems, and methods for assaying cells using cell-substrate impedance monitoring. In one aspect, the invention provides cell-substrate impedance monitoring devices that comprise electrode arrays on a nonconducting substrate, ... | 07/14/2009 |
| 7062940 | Carved pearl A pearl including a nucleus optionally including a gem and a nacre coating. The nacre coating partially coats but does not fully coat the nucleus thereby exposing at least a portion of the nucleus. ... | 06/20/2006 |
| 7537477 | Power cable tension control device The present invention includes a power cable tension control device having at one end an adapter capable of insertion into a computer port and at the opposing end a cable retaining structure for retaining a power cable, such as an AC power cable. The adapter does no... | 05/26/2009 |
| D573851 | Fork with angled prongs | 07/29/2008 |
| 7396561 | Surface-attached polyfunctional polymer networks for sensor chips The invention relates to polyfunctional polymer networks comprising an assembly of cross-linked polymer subchains attached to a surface, with each polymer subchain comprising a multitude of identical or different repeating units carrying one or more functional group... | 07/08/2008 |
| D568041 | Adjustable bag for transporting fluid apparatus | 05/06/2008 |
| D550104 | Organic chemistry drafting template | 09/04/2007 |
| 7087021 | Methods of screening for genes and agents affecting cardiac function The relationship between aging and decreased cardiac function is well known. However, the human cardiac system is extremely complex and humans are very long-lived animals. Therefore, there is a need for simple models of the heart that can be rapidly tested over time... | 08/08/2006 |
| 6908489 | Articulated artificial finger assembly Disclosed is an articulated artificial finger assembly, which can be controlled by the remaining portion of an amputated finger. An adjacent finger is used to manipulate the device when no finger is present. When the stump or adjacent finger begins to bend at the fi... | 06/21/2005 |