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3M employee and church chorister Art Fry needed something to temporarily mark pages in his hymnal. He was in luck because his colleague, Spencer Silver, accidentally developed a glue that was too weak for other purposes. After initially discouraging consumer response, Post-it Notes became a hit in 1979.
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| Number | Title | Issue Date |
| 8163717 | Dual chain synthetic heparin-binding growth factor analogs The invention provides synthetic heparin-binding growth factor analogs having two peptide chains each branched from a branch moiety, such as trifunctional amino acid residues, the branch moieties separated by a first linker of from 3 to about 20 backbone atoms, whic... | 04/24/2012 |
| 8157872 | System and method for creating ink art A system, method and apparatus is disclosed for coloring a substantially wicking substrate comprising applying to a substantially wicking substrate an ink comprising a first dye and a second dye to define a region of reference; applying a first solvent to the substa... | 04/17/2012 |
| 8118754 | Magnetic needle biopsy An apparatus and method for performing biopsies in-vivo using magnetically labeled nanoparticles is disclosed. One embodiment of the apparatus is called a magnetic needle. When used in a biopsy, one embodiment of the present invention collects diseased cells in-vivo... | 02/21/2012 |
| 8101570 | Single branch heparin-binding growth factor analogs A heparin-binding growth factor (HBGF) analog having two substantially similar sequences (homodimeric sequences) branched from a single amino acid residue, where the sequences are analogs of a particular HBGF that binds to a heparin-binding growth factor receptor (H... | 01/24/2012 |
| D651820 | Tailgate bench | 01/10/2012 |
| 8060179 | Biomagnetic detection and treatment of Alzheimer's Disease SQUID imaging of a subject's head after the subject having been administered superparamagnetic nanoparticles comprising: an iron-containing core, a coating covering the core and a probe molecule conjugated to the coating wherein the probe molecule locates the superp... | 11/15/2011 |
| 8057552 | System and method for creating ink art A system, method and apparatus is disclosed for coloring a substantially wicking substrate comprising applying to a substantially wicking substrate an ink comprising a first dye and a second dye applying a first solvent to the substantially wicking substrate to move... | 11/15/2011 |
| D648892 | Cigar holder | 11/15/2011 |
| 7988287 | Objective traumatic brain injury assessment system and method A system and method for determining the neurological function of a patient by examining ocular responses. ... | 08/02/2011 |
| 7981862 | Composition comprising BMP-2 amplifier/co-activator for enhancement of osteogenesis A composition comprising a synthetic growth factor analogue comprising a non-growth factor heparin binding region, a linker and a sequence that binds specifically to a cell surface receptor and an osteoconductive material where the synthetic growth factor analogue i... | 07/19/2011 |
| D640904 | Wine aerator | 07/05/2011 |
| 7963289 | Hair accessory to achieve a fuller ponytail A hair accessory made to increase the body and fullness of a ponytail or pig tails. The hair accessory includes a hinged pair of first and second portions movable between an open position and a closed position, each portion having a hinged end and an opposite end, i... | 06/21/2011 |
| 7955296 | Biologically enhanced irrigants Compositions, systems and methods utilizing engineered surgical irrigants providing delivery of components with therapeutic or other secondary benefits. Engineered irrigants provide targeted delivery of desired agents, including agents for propulsion of nano-devices... | 06/07/2011 |
| D630930 | Multi-spoke geodesic hub | 01/18/2011 |
| 7820172 | Laminin-derived multi-domain peptides Multi-domain peptides including a heparin-binding peptide sequence covalently linked to a linker sequence, which linker sequence is covalently linked to a trifunctional amino acid residue forming a branch with two arms, with substantially similar (homodimeric) cellu... | 10/26/2010 |
| 7819864 | Electrosurgery devices Devices for electrosurgery by means of oxy-hydro combustion. Deleterious effects to tissue are minimized by means of control of acid-base shift reactions, which reactions can further be employed to control oxy-hydro combustion reactions. In one embodiment, radiofreq... | 10/26/2010 |
| 7819861 | Methods for electrosurgical electrolysis Methods for electrosurgical electrolysis for treating tissue within a body, including methods that operate in an electrolyzable medium, including an aqueous electrolyzable medium, by means of electrolysis, and optionally by means of oxy-hydrogen combustion for use i... | 10/26/2010 |
| 7819136 | Hand washing timer A hand washing timer with a sensor for assisting a user in washing his or her hands for a proper amount of time, for example in accordance with one or more health code regulations. The timer can also include a display, a solenoid valve, a pressure sensor, and/or a f... | 10/26/2010 |
| 7771422 | Methods and devices for electrosurgery Devices and methods for electrolytic electrosurgery wherein a detector is located proximal to an active electrode on an electrosurgical probe, optionally disposed between the active electrode and a return electrode, the detector detecting at least on parameter relat... | 08/10/2010 |
| D619431 | Wine aerator | 07/13/2010 |
| D617433 | Lavatory system | 06/08/2010 |
| 7713690 | Luminous bacteria and methods for the isolation, identification and quantitation of toxicants Methods for the isolation and identification of a toxicant in a sample are disclosed. Luminescent biological agents (i.e., bacteria) having sensitivity to a toxicant or an isolatable component in a sample are used to provide visually discernable zones of luminescent... | 05/11/2010 |
| 7713269 | Devices for electrosurgery Devices for electrosurgery by means of oxy-hydro combustion and methods for use of such devices in electrosurgical procedures. Provided are devices for combustion of oxygen and hydrogen, or other hydrocarbon fuels, wherein oxygen and hydrogen may be generated by ele... | 05/11/2010 |
| D615042 | Medical device plug for a surgical tool | 05/04/2010 |
| 7700563 | Synthetic heparin-binding factor analogs The invention provides synthetic heparin-binding growth factor analogs having at least one peptide chain, and preferably two peptide chains branched from a dipeptide branch moiety composed of two trifunctional amino acid residues, which peptide chain or chains bind ... | 04/20/2010 |
| 7671012 | Formulations and methods for delivery of growth factor analogs Formulations, kits and methods for bone or cartilage repair, including treatment of osteogenic defects, including formulations of synthetic heparin-binding growth factor analogs, non-ionic polymers, gelling agents and calcium-containing agents. ... | 03/02/2010 |
| 7670799 | Method for making 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine (TCPP) solution and composition comprising TCPP Presented is a method of solubilizing TCPP, as well as a composition comprising TCPP solubilized by this method. ... | 03/02/2010 |
| 7668351 | System and method for automation of morphological segmentation of bio-images Medical images are automatically segmented by customizing the morphological segmentation of features identified in the image based upon statistical analysis of the features within each region to be analyzed. The statistical description of the features, as reported t... | 02/23/2010 |
| D607092 | Lavatory system | 12/29/2009 |
| 7598224 | Dual chain synthetic heparin-binding growth factor analogs The invention provides synthetic heparin-binding growth factor analogs having two peptide chains each branched from a branch moiety, such as trifunctional amino acid residues, the branch moieties separated by a first linker of from 3 to about 20 backbone atoms, whic... | 10/06/2009 |
| D600808 | Medical device handle for a surgical tool | 09/22/2009 |
| 7587097 | Max entropy optimized retinal camera An enhanced entropy camera provides enhanced image quality by utilizing a custom analog-to-digital conversion function. The analog-to-digital conversion occurs according to a custom non-linear quantization function that provides enhanced entropy in the digitized ima... | 09/08/2009 |
| 7549989 | Electrosurgery devices Devices for electrosurgery by means of oxy-hydro combustion. Deleterious effects to tissue are minimized by means of control of acid-base shift reactions, which reactions can further be employed to control oxy-hydro combustion reactions. In one embodiment, radiofreq... | 06/23/2009 |
| 7112347 | Sandwich package and method of packaging A system which enables fillings (such as sandwich fillings) to be kept separate from bread. The system thus enables the fillings and bread to be stored and transported together without the bread getting soggy. The present invention also provides a way to quickly dis... | 09/26/2006 |
| 7528105 | Heterodimeric chain synthetic heparin-binding growth factor analogs The invention provides synthetic heparin-binding growth factor analogs having at least two different peptide growth factor analog chains, or alternatively two groups of two different peptide chains branched from branch moieties including trifunctional amino acid res... | 05/05/2009 |
| 7491812 | Copper-inducible promoter system The present invention comprises a copper-inducible promoter system of yeast for the controlled expression of recombinant genes. The invention comprises a promoter element comprising at least two tandemly-repeated MRE sequences and a minimal TATA element from the 35S... | 02/17/2009 |
| 7482427 | Positive modulator of bone morphogenic protein-2 Compounds of the present invention of formula I and formula II are disclosed in the specification and wherein the compounds are modulators of Bone Morphogenic Protein activity. Compounds are synthetic peptides having a non-growth factor heparin binding region, a lin... | 01/27/2009 |
| 7468210 | Cross-linked heparin coatings and methods A thromboresistant coating for a medical device, method of coating and coated medical device, the coating including an in situ cross-linked co-polymer of a cross-linkable biomolecule, preferably an adsorbable biomolecule such as a heparin activity biomolecule with a... | 12/23/2008 |
| 7445619 | Devices for electrosurgery Devices for electrosurgery by means of oxy-hydro combustion and methods for use of such devices in electrosurgical procedures. Provided are devices for combustion of oxygen and hydrogen, or other hydrocarbon fuels, wherein oxygen and hydrogen may be generated by ele... | 11/04/2008 |
| 7414028 | Growth factor analogs The invention provides synthetic heparin-binding growth factor analogs of formulas I or II as given in the specification, having two peptide chains branched from a dipeptide branch moiety composed of at least one and preferably two trifunctional amino acid residues,... | 08/19/2008 |
