Did You Know...
...that the inventor of the electric motor was a blacksmith named Thomas Davenport? Described as "a brilliantly unsuccessful inventor", Davenport invented the first rotary electric motor. In 1836 he headed out -- on foot -- from his Vermont home to file a patent application at the Patent Office in Washington, D.C. By the time he got there, he had squandered away his money and couldn't afford the $30 filing fee so he turned around and went home. When he later mailed in his application with money he'd raised, the Patent office was destroyed in a fire. He did finally get credit for his invention on Feb. 5, 1837.
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| Number | Title | Issue Date |
| 7872003 | Pharmaceutical compounds Fused pyrimidines of formula (I): wherein R1-R3, A and n have any of the values described in the specification; and pharmaceutically acceptable salts thereof; have activity as inhibitors of PI3K and ma... | 01/18/2011 |
| 7781587 | Solubilized topoisomerase poisons The invention provides compounds of formula I: wherein A, B, W, Y, Z, and R1 have any of the meanings defined in the specification and their pharmaceutically acceptable salts. T... | 08/24/2010 |
| 7781433 | Pharmaceutical compounds A thienopyrimidine of formula (I): and the pharmaceutically acceptable salts thereof have activity as inhibitors of PI3K with selectivity for the P110α subtype, and may be used to treat diseases and disorders arising from ... | 08/24/2010 |
| 7776856 | Pharmaceutical compounds Fused pyrimidines of formula (I): where A is a thiophene or furan ring and R1-R3 and n are defined in the specification. These compounds have activity as inhibitors of PI3K and may thus be used to trea... | 08/17/2010 |
| 7524373 | Apparatus and semiconductor co-crystal The invention provides a method to enforce face-to-face stacking of organic semiconductors in the solid state that employs semiconductor co-crystal formers (SCCFs), to align semiconductor building blocks (SBBs). Single-crystal X-ray analysis reveals n-orbital overla... | 04/28/2009 |
| 7452901 | Anti-cancer phosphonate analogs The invention is related to phosphorus substituted anti-cancer compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds... | 11/18/2008 |
| 7432261 | Anti-inflammatory phosphonate compounds The invention is related to phosphorus substituted anti-inflammatory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such com... | 10/07/2008 |
| 7429571 | Therapeutic furopyrimidines and thienopyrimidines The invention provides compounds of formula I, II, and III as described herein, as well as pharmaceutical compositions comprising the compounds, and synthetic methods and intermediates that are useful for preparing the compounds. The compounds of formula I, II, and ... | 09/30/2008 |
| 7427636 | Inosine monophosphate dehydrogenase inhibitory phosphonate compounds The invention is related to phosphorus substituted IMPDH inhibitory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such comp... | 09/23/2008 |
| 7427624 | Purine nucleoside phosphorylase inhibitory phosphonate compounds The invention is related to phosphorus substituted purine nucleoside phosphorylase inhibitory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates usef... | 09/23/2008 |
| 7417055 | Kinase inhibitory phosphonate analogs The invention is related to phosphorus substituted kinase inhibitory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such com... | 08/26/2008 |
| 7384629 | Biological control of nematodes with The present invention provides a novel isolated and purified fungus Hirsutella minnesotensis. The present invention also provides a pesticidal composition of an effective amount of an isolated and purified fungal strain of Hirsutella rhossiliensis or | 06/10/2008 |
