Viksnins Harris & Padys PLLP - US Patent Attorneys and Agents

Attorney: Viksnins Harris & Padys PLLP

Number of patents: 88
Last date: April 26, 2011

Number	Title	Issue Date
7931893	Methods for producing and using in vivo pseudotyped retroviruses using envelope glycoproteins from lymphocytic choriomeningitis virus (LCMV) The present invention provides novel pseudotyped retroviral vectors that can transduce human and other cells. Vectors are provided that are packaged efficiently in packaging cells and cell lines to generate high titer recombinant virus stocks expressing novel envelo...	04/26/2011
7928248	Benzopyran and benzoxepin PI3K inhibitor compounds and methods of use Benzopyran and benzoxepin compounds of Formulas I and II, and including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting lipid kinases including p110 alpha and other isoforms ...	04/19/2011
7909179	Modified polyamide matrices and methods for their preparation The invention provides novel polymer matrices and methods for preparing polymer matrices. ...	03/22/2011
7902228	Schweinfurthin analogues Methods and intermediates for preparing enantiomerically enriched Schweinfurthin analogs which are useful for the treatment of cancer, as well as novel Schweinfurthin analogs having anti-cancer activity, compositions comprising such analogs and therapeutic methods c...	03/08/2011
7893059	Thiazolopyrimidine PI3K inhibitor compounds and methods of use Compounds of Formulas Ia and Ib, and including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting lipid kinases including PI3K, and for treating disorders such as cancer mediate...	02/22/2011
7888452	Low band gap semiconducting polymers The invention provides a polymer of formula I: wherein A, B, D, E, R1, and R2 have any of the values defined in the specification, as well as electrical devices comprising such polymers. ...	02/15/2011
7888352	Phosphoinositide 3-kinase inhibitor compounds and methods of use Compounds of Formulas Ia-d where X is S or O, mor is a morpholine group, and R3 is a monocyclic heteroaryl group, and including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful fo...	02/15/2011
7846929	Phosphoinositide 3-kinase inhibitor compounds and methods of use Compounds of Formulas Ia and Ib, and including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting lipid kinases including PI3K, and for treating disorders such as cancer mediate...	12/07/2010
7858627	Topoisomerase-targeting agents The invention provides compounds of formula I or formula II: wherein: the bond represented by is a single bond or a double bond, and R1—R5, X, and Y have any of the meanings defined in ...	12/28/2010
7858090	Artificial antibody polypeptides A fibronectin type III (Fn3) polypeptide monobody, a nucleic acid molecule encoding said monobody, and a variegated nucleic acid library encoding said monobody, are provided by the invention. Also provided are methods of preparing a Fn3 polypeptide monobody, and kit...	12/28/2010
7851172	Biomarkers of mild cognitive impairment and alzheimer's disease A method for quantifying a neurodegenerative disorder in a patient that includes obtaining a fluid sample from the subject; measuring a protein biomarker complex in said fluid sample and correlating the measurement with mild cognitive impairment or Alzheimer's disea...	12/14/2010
7811371	Rubber-polyolefin surface covering A surface covering comprising between 5 and 50% w/w of thermoplastic material, between 5 and 50% w/w of elastomer material, between 5 and 20% w/w of a high styrene resin, between 25 and 70% w/w of filler and between 1% and 10% w/w of vulcanisation system. ...	10/12/2010
7799782	P38 inhibitors and methods of use thereof This invention relates to inhibitors of p38 and methods of utilizing the inhibitors and pharmaceutical compositions thereof in the treatment and prevention of various disorders mediated by p38. ...	09/21/2010
7795282	Mitotic kinesin inhibitors and methods of use thereof This invention relates to inhibitors of mitotic kinesins, particularly KSP, and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing the inhibitors and pha...	09/14/2010
7772416	Data storage materials The invention provides metal-organic complexes useful for storing information in an information storage system. The invention also provides methods for forming such complexes on a substrate, as well as apparatuses and systems comprising such complexes. ...	08/10/2010
7771702	Sulfur-tolerant catalysts and related precursors and processes The invention provides active, affordable, durable, and sulfur-tolerant catalysts and related precursors and processes useful in hydrogen production. The catalysts have a wide applicability. For example, in one embodiment, the invention provides sulfur-tolerant cata...	08/10/2010
7750002	Pharmaceutical compounds Fused pyrimidines of formula (I): wherein R1-R3, A and n have any of the values described in the specification; and pharmaceutically acceptable salts thereof, have activity as inhibitors of PI3K and ma...	07/06/2010
7741469	Compositions for treating hearing loss and methods of use thereof This invention also relates to compounds, compositions, and methods useful for modulating the expression and activity of genes encoding proteins involved in deafness caused by dominant negative mechanism of action by RNA interference (RNAi) using small nucleic acid ...	06/22/2010
7728001	Opioid receptor ligands and methods for their preparation The invention provides novel compounds of formula I: that are opioid receptor ligands. The invention also provides pharmaceutical compositions comprising such compounds as well as methods for treating diseases associated wi...	06/01/2010
7723330	Heterobicyclic pyrazole compounds and methods of use Compounds of Formulas Ia and Ib, and stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting receptor tyrosine kinases and for treating disorders mediated thereby. Methods of using c...	05/25/2010
7723118	Compositions and methods for simultaneous detection of volatile sulfur compounds and polyamines Disclosed are compositions and methods useful for the rapid and facile simultaneous detection of malodorous bacterial metabolites in samples of expired breath and other fluids. The invention enables estimation, by simple visual inspection and comparison against stan...	05/25/2010
7708150	Process for preparing semipermeable membranes The invention provides methods for preparing reverse osmosis membranes having improved permeability as well as membranes prepared by such methods. ...	05/04/2010
7687475	RNA interference in respiratory epithelial cells The present invention is directed to small interfering RNA molecules targeted against a gene of interest in respiratory epithelial cells, and methods of using these RNA molecules. ...	03/30/2010
7666398	Polyanhydride linkers for production of drug polymers and drug polymer compositions produced thereby Polyanhydrides which link low molecular weight drugs containing a carboxylic acid group and an amine, thiol, alcohol or phenol group within their structure into polymeric drug delivery systems are provided. Also provided are methods of producing polymeric drug deliv...	02/23/2010
7662864	Solution polymerization processes to prepare a polymer that degrades to release a physiologically active agent Anhydride polymers that release active or activatable agent(s) have pre-selected properties such as molecular weight, flexibility, hardness, adhesiveness, and other valuable properties. The polymers are suitable for use in compositions, formulations, coatings, devic...	02/16/2010
7658872	Process for preparing semipermeable membranes having improved permeability The invention provides methods for preparing reverse osmosis membranes having improved permeability as well as membranes prepared by such methods. ...	02/09/2010
7638145	Cultivated agarwood The present invention provides agarwood from cultivated trees, and methods of generating agarwood in cultivated trees. ...	12/29/2009
7635483	Streptococcal C5a peptidase vaccine Novel vaccines for use against β-hemolytic Streptococcus colonization or infection are disclosed. The vaccines contain an immunogenic amount of a variant of streptococcal C5a peptidase (SCP). Also disclosed is a method of protecting a susceptible mammal agai...	12/22/2009
7575687	Membranes and methods useful for caustic applications The invention provides methods for purifying caustic feed streams using membranes that comprise polysulfonamide matrices. ...	08/18/2009
7566716	Imidazopyrazines as Raf inhibitor compounds Compounds of Formula I are useful for inhibiting Raf kinase and for treating disorders mediated thereby. Methods of using compounds of Formula I, and stereoisomers, tautomers, solvates and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo...	07/28/2009
7524966	Method for preparing ladderanes Ditopic molecules in the form of linear reaction templates have been used to construct ladder-like hydrocarbons known as [n]-ladderanes (n=3,5). The templates assemble and position reactant molecules in the solid state by way of hydrogen bonds for [2+2] photodimeriz...	04/28/2009
7517883	Solubilized topoisomerase poisons The invention provides compounds of formula I: wherein A, B, W, Y, Z, and R1 have any of the meanings defined in the specification and their pharmaceutically acceptable salts. The invention also provides ...	04/14/2009
7517867	Topoisomerase-targeting agents The invention provides compounds of formula I or formula II: wherein: the bond represented by — is a single bond or a double bond, and R1-R5, X, and Y have any of the meanings defined in th...	04/14/2009
7514548	Methods of inhibiting COX-2 The present invention provides RNA molecules (e.g., antisense, RNAi, or siRNA) specific for COX-2, and further provides methods of reducing expression of COX-2 in cells (e.g., cancer cells). ...	04/07/2009
7514410	Hepatitis C therapies The invention provides methods for treating hepatitis C viral infections and related viral infections, as well as compounds and compositions that are useful for treating such infections. ...	04/07/2009
7510717	Non-toxic mutants of pathogenic gram-negative bacteria A method is provided for identifying, isolating, and producing htrB mutants of gram-negative bacterial pathogens. The method comprises mutating the htrB gene of a gram-negative bacterial pathogen so that there is a lack of a functional htrB protein, resulting in a m...	03/31/2009
7491829	RAF inhibitor compounds and methods Pyrazolyl compounds of Formulas Ia and Ib are useful for inhibiting Raf kinase and for treating disorders mediated thereby. Methods of using pyrazolyl compounds for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cell...	02/17/2009
7481866	Gas storage materials and devices The invention provides a porous metal-organic framework that can be used to store gases, such as hydrogen. Also provided is metal-organic framework comprising bifunctional metallic bridging groups and organic nodes having three or more points of connection, wherein ...	01/27/2009
7470724	Phosphonate compounds having immuno-modulatory activity The invention is related to phosphonate substituted compounds having immuno-modulatory activity, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for p...	12/30/2008
7470802	Micelle assemblies The invention encompasses micelle assemblies, compositions having micelle assemblies, and methods for preparing micelle assemblies and compositions thereof. Also, the invention encompasses compounds of the formula: A-X-Y-Z-R1 wherein A is a carboxy group ...	12/30/2008

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