"What can be more palpably absurd than the prospect held out of locomotives traveling twice as fast as stagecoaches?"
The Quarterly Review ; March edition, 1825
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| Number | Title | Issue Date |
| 5096894 | Rice dextrin oral rehydration solution An improved oral rehydration solution comprising a mixture of rice dextrin and required electrolytes is provided. The functionality of the rice dextrin in oral rehydration solutions is superior to glucose in infants with chronic diarrhea resulting in lowe... | 03/17/1992 |
| 5077305 | Thiazole carboxylic acids and esters Heterocyclic acids and esters useful as inhibitors of mammalian blood platelet aggregation characterized by Formula I or II are disclosed. HET1 -(CH2)n CO2 R (I) ##STR1## Formula I compounds ... | 12/31/1991 |
| 5047246 | Direct compression cyclophosphamide tablet A directly compressible pharmaceutical composition comprising cyclophosphamide and a partially or fully pregelatinized starch is disclosed. The pharmaceutical composition, when directly compressed into a tablet, exhibits unexpected stability when compared... | 09/10/1991 |
| 5034409 | Pyrrole carboxylic acids and esters for blood platelet aggregation inhibition Heterocyclic acids and esters useful as inhibitors of mammalian blood platelet aggregation characterized by Formula I are disclosed. HET1 --(CH2)n CO2 R (I) Formula I compounds are those wherein n is 6-... | 07/23/1991 |
| 5021415 | Triazine carboxylic acids and esters Heterocyclic acids and esters useful as inhibitors of mammalian blood platelet aggregation characterized by Formula I or II are disclosed. ##STR1## Formula I compounds are those wherein n is 6-9, R is hydrogen, lower alkyl or an alkali metal ion, and... | 06/04/1991 |
| 5011283 | Flow cell support device A support device for a workpiece, such as a spectrophotometric flow cell is provided. The device includes a base plate, a mounting bar attached to the base plate, a support arm slidably mounted on the base plate/mounting bar assembly, an adjustment plug c... | 04/30/1991 |
| 5011851 | Imidazole carboxylic acids and esters and inhibition of blood platelet aggregation therewith Heterocyclic acids and esters useful as inhibitors of mammalian blood platelet aggregation characterized by Formula I or II are disclosed. HET1 --(CH2)n CO2 R (I) ##STR1## Formula I compounds ... | 04/30/1991 |
| 4994476 | Dihydropyridin-3,5-dicarboxylates incorporating aryloxypropanolamine moieties A series of compounds useful in treating cardiovascular disorders due to the combined expression of both ଲ-block and calcium-block activity by these agents. This useful combination of actions is effected by a novel combination of structural subunits... | 02/19/1991 |
| 4992439 | Pyridazine carboxylic acids and esters Heterocyclic acids andesters useful as inhibitors of mammalian blood platelet aggregation characterized by Formula I or II are disclosed. ##STR1## Formula I compounds are those wherein n is 6-9, R is hydrogen, lower alkyl or an alkali metal ion, and ... | 02/12/1991 |
| 4990344 | Method for making soluble rice protein concentrate and the product produced therefrom This invention concerns a process for preparing soluble rice protein concentrate with reduced levels of manganese, aluminum, selenium and phytic acid and improved digestibility from rice raw material comprising: digesting the raw material reduced in particle s... | 02/05/1991 |
| 4983610 | Pyrimidine carboxylic acids and esters Heterocyclic acids and esters useful as inhibitors of mammalian blood platelet aggregation characterized by Formula I are disclosed. HET1 --(CH2)n CO2 R (I) Formula I compounds are those wherein n is 6-... | 01/08/1991 |
| 4970225 | Imidazolidine carboxylic acids and esters as blood platelet aggregation inhibitors Heterocyclic acids and esters useful as inhibitors of mammalian blood platelet aggregation characterized by Formula I are disclosed. HET1 -(CH2)n CO2 R (I) Formula I compounds are those wherein n is 6-... | 11/13/1990 |
| 4956379 | Pyrazole carboxylic acids and esters and inhibition of blood platelet aggregation therewith Heterocyclic acids and esters useful as inhibitors of mammalian blood platelet aggregation characterized by Formula I or II are disclosed. HET1 --(CH2)n CO2 R (I) ##STR1## Formula I compounds ... | 09/11/1990 |
| 4956376 | Tetrazole carboxylic acids and esters and inhibition of blood platelet aggregation therewith Heterocyclic acids and esters useful as inhibitors of mammalian blood platelet aggregation characterized by Formula I or II are disclosed. ##STR1## Formula I compounds are those wherein n is 6-9, R is hydrogen, lower alkyl or an alkali metal ion, and... | 09/11/1990 |
| 4956182 | Direct compression cholestyramine tablet and solvent-free coating therefor A directly compressed cholestyramine tablet with a solvent-free coating is disclosed. The inner core of the tablet is made up of cholestyramine agglomerates consisting of numerous small, irregularly-shaped, jagged-edged fragments having relatively few smo... | 09/11/1990 |
| 4943573 | Imidazo[4,5-b]quinolinyloxyalkanoic acid amides with enhanced water solubility A novel series of 2,3-dihydro-2-oxo-1H-imidazo[4,5-b]quinolinyloxyalkanoic acid amides having enhanced water solubility is disclosed of the formula ##STR1## wherein n is 3 to 5; R1 is alkyl of 1 to 4 carbon atoms; R2 is hydrogen... | 07/24/1990 |
| 4882472 | Fluoride supplement calculator A fluoride supplement calculator utilizes two concentrically positioned relatively rotatable disks. A front disk has a plurality of fluoride level apertures which overlie groups of fluoride dosage amounts carried on the second disk. An age scale is also p... | 11/21/1989 |
| 4830861 | Low manganese high protein rice flour A method for preparing high protein rice flour (HPRF) containing low manganese is disclosed wherein essential steps comprise: blending rice flour and water at a pH of 3.4 to 4.6; separating the insoluble washed rice flour; resuspending the washed rice flour and adj... | 05/16/1989 |
| 4814455 | Dihydro-3,5-dicarboxylates A series of compounds of the 1,4-dihydropyridine class with a 3-carboxylate group linked to an alkyleneaminoalkylene heteroatom have been prepared possessing the general formula ##STR1## wherein R2, R5 and R6 are inde... | 03/21/1989 |
| 4788862 | Plastic measuring scoop with foldable handle A plastic molded measuring scoop assembly includes a generally cylindrical measuring scoop and a hinged handle assembly which is comprised of a fixed inner handle portion and a foldable outer handle portion. The inner handle portion carries a latching cha... | 12/06/1988 |
| 4775674 | Imidazoquinolinylether derivatives useful as phosphodiesterase and blood aggregation inhibitors Novel series of 2,3-dihydro-2-oxo-1H-imidazo[4,5-b]quinolinyl ether derivatives of formula ##STR1## wherein R1 is hydrogen, lower alkly, benzyl; R2 is hydrogen, halogen, lower alkyl, lower alkoxy; Alk is alkylene; Y is hydroxy a... | 10/04/1988 |
| 4755512 | Pharmaceutically useful dihydropyridinyldicarboxylate amides and esters incorporating arylpiperazinylalkyl moities A series of 1,4-dihydropyridin-3,5-yl dicarboxylic acid amides and esters incorporating an arylpiperazinylalkyl moiety have been prepared possessing the general formula ##STR1## wherein R4 is cycloalkyl, aryl or hetaryl, generally with ... | 07/05/1988 |
| 4701528 | Intermediates useful in the preparation of 3,4-dihydro-4-oxothieno[2,3-d]pyrimidine-2-carboxylates and process for preparing same There are disclosed compounds of Formulas I and II: ##STR1## wherein R1 and R2 may be hydrogen, lower alkyl having from 1 to 8 carbon atoms, lower alkenyl having from 3 to 6 carbon atoms, lower alkoxy having from 1 to 6 carbon a... | 10/20/1987 |
| 4701459 | 7-amino-1,3-dihydro-2H-imidazo[4,5-b]quinolin 2-ones and method for inhibiting phosphodiesterase and blood platelet aggregation Novel series of 2,3-dihydro-2-oxo-1H-imidazo[4,5-b]quinolinyl amine derivatives of Formula ##STR1## wherein R1 is hydrogen, lower alkyl; R2 is hydrogen, lower alkyl, lower alkoxy, halogen; R3 is hydrogen, lower alkyl;... | 10/20/1987 |
| 4697004 | Process for preparing low phytate soy protein isolate A high quality soy protein isolate with significantly reduced aluminum content and substantially free of phytic acid and phytate complexes is prepared by aqueous extraction of defatted particulated soybeans at pH 8 to 10, and at a temperature above 65° C... | 09/29/1987 |
| 4668686 | Imidazoquinoline antithrombrogenic cardiotonic agents Novel series of 1,3-dihydro-2H-imidazo[4,5-b]quinolin-2-ones of the Formula ##STR1## wherein R1 is halogen, lower alkyl, lower alkoxy, trifluoromethyl; R2 is hydrogen, halogen, lower alkyl, lower alkoxy; R3 is hydroge... | 05/26/1987 |
| 4642345 | 6,7-dihydro-3H-imidazo[1,2-a]-purine-9(4H)-ones Imidazopyrimidinones and other diazaheterocyclopyrimidinones having an additional fused imidazole or triazole ring have utility as bronchodilators, mediator release inhibitors, phosphodiesterase inhibitors, and peripheral vasodilators. They are orally act... | 02/10/1987 |
| 4640921 | Treatment of sexual dysfunction with buspirone Buspirone and its pharmaceutically acceptable salts are useful in treating patients of both sexes suffering from sexual dysfunction.... | 02/03/1987 |
| 4634703 | Method for alleviation of panic disorders Buspirone and its pharmaceutically acceptable salts are useful in alleviation of panic disorders which can take the form of clinical syndromes comprising, for example, panic attacks, agoraphobia and phobic anxiety.... | 01/06/1987 |
| 4613600 | Antidepressant 1,2,4-triazolone compounds 2-[3-[4-(3-Halophenyl)-1-piperazinyl]propyl]-5-(1-hydroxyethyl)-2,4-dihydro -[4-phenoxyalkyl-3H-1,2,4-triazol-3-ones and closely related compounds are psychotropic agents having promise as antidepressants by virtue of their receptor site binding affinity p... | 09/23/1986 |
| 4596884 | 4-(2-phenoxyethyl)-1,2,4-triazolone process intermediates An improved process for the preparation of 5-ethyl-4-(2-phenoxyethyl)-1,2,4-triazolone, a useful intermediate in the synthesis of antidepressant 1,2,4-triazolones typified by 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-4-(2-phenoxethyl)-2 H... | 06/24/1986 |
| 4590196 | Analgesic 1,2-benzisothiazol-3-ylpiperazine derivatives A series of non-opiate analgesics of Formula I ##STR1## wherein R1 is hydrogen, alkyl, aralkyl, or aryloxyalkyl; R2 is alkyl or hydrogen; and R3 and R4 are independently selected from hydrogen, alkyl, acylo... | 05/20/1986 |
| 4581357 | Antipsychotic 5-fluoro-pyrimidin-2-yl piperazine compound 8-[4-[4-(5-Fluoro-pyrimidin-2-yl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decan e-7,9-dione and its pharmaceutically acceptable salts demonstrate antipsychotic activity.... | 04/08/1986 |
| 4537883 | Lyophilized cyclophosphamide A lyophilized pharmaceutical solid composition containing cyclophosphamide for reconstitution with water to provide a solution for oral or parenteral administration. This lyophilized cyclophosphamide solid composition demonstrates improved stability, solu... | 08/27/1985 |
| 4524206 | 1-Heteroaryl-4-(2,5-pyrrolidinedion-1-yl)alkyl)piperazine derivatives Disubstituted N,N'-piperazinyl derivatives are disclosed wherein one substituent is heteroaryl and the other is alkylene attached to the ring nitrogen of substituted 2,5-pyrrolidinedion-1-yl moieties. The substitution pattern of the pyrrolidinedione ring ... | 06/18/1985 |
| 4517188 | 1-Pyrimidinyloxy-3-hetaryl-alkylamino-2-propanols 1-(4-Pyrimidinyloxy)-3-(hetarylalkylamino)-2-propanols are cardiovascular agents having a range of vasodilator and adrenergic beta-receptor blocking activities making these compounds useful anti-hypertensive agents. Preferred compounds bear a hydrazino or... | 05/14/1985 |
| 4511163 | Adaptable tip tubing connector An improved tubing connector with a connecting tip designed to adapt all sizes of tubing commonly employed in nasogastric and gastrostomy feeding. This tubing connector comprises a one-piece hollow unit having at one end a smooth tapered sleeve with an ou... | 04/16/1985 |
| 4497800 | Stable liquid diet composition A nutritionally complete ready-to-use liquid diet for providing total patient nourishment. This diet contains a source of protein equivalent comprised of free amino acids and small peptides; a carbohydrate source comprised of maltodextrin with a dextrose ... | 02/05/1985 |
| 4463176 | Process for resolution of optical isomers A process for resolving a racemic modification of ଲ-adrenergic aryl- or hetaryl-oxypropanolamines such as (b1;)-2-[2-hydroxy-3-[[2-(1H-indol-3-yl)-1,1-dimethylethyl]amino]propoxy] benzonitrile into its individual enantiomers is described. The proce... | 07/31/1984 |
| 4454324 | Process for production of encainide An improved process for the preparation of 4-methoxy-2'-{2-(1-methyl-2-piperidyl)ethyl}benzanilide has been developed. The process comprises essentially three steps starting with methyl anthranilate and 2-picoline and features a novel low-pressure hy... | 06/12/1984 |