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Attorney: Uloth; Robert H.


Number of patents: 70
Last date: March 17, 1992

1    
NumberTitleIssue Date
5096894Rice dextrin oral rehydration solution
An improved oral rehydration solution comprising a mixture of rice dextrin and required electrolytes is provided. The functionality of the rice dextrin in oral rehydration solutions is superior to glucose in infants with chronic diarrhea resulting in lowe...
03/17/1992
5077305Thiazole carboxylic acids and esters
Heterocyclic acids and esters useful as inhibitors of mammalian blood platelet aggregation characterized by Formula I or II are disclosed. HET1 -(CH2)n CO2 R (I) ##STR1## Formula I compounds ...
12/31/1991
5047246Direct compression cyclophosphamide tablet
A directly compressible pharmaceutical composition comprising cyclophosphamide and a partially or fully pregelatinized starch is disclosed. The pharmaceutical composition, when directly compressed into a tablet, exhibits unexpected stability when compared...
09/10/1991
5034409Pyrrole carboxylic acids and esters for blood platelet aggregation inhibition
Heterocyclic acids and esters useful as inhibitors of mammalian blood platelet aggregation characterized by Formula I are disclosed. HET1 --(CH2)n CO2 R (I) Formula I compounds are those wherein n is 6-...
07/23/1991
5021415Triazine carboxylic acids and esters
Heterocyclic acids and esters useful as inhibitors of mammalian blood platelet aggregation characterized by Formula I or II are disclosed. ##STR1## Formula I compounds are those wherein n is 6-9, R is hydrogen, lower alkyl or an alkali metal ion, and...
06/04/1991
5011283Flow cell support device
A support device for a workpiece, such as a spectrophotometric flow cell is provided. The device includes a base plate, a mounting bar attached to the base plate, a support arm slidably mounted on the base plate/mounting bar assembly, an adjustment plug c...
04/30/1991
5011851Imidazole carboxylic acids and esters and inhibition of blood platelet aggregation therewith
Heterocyclic acids and esters useful as inhibitors of mammalian blood platelet aggregation characterized by Formula I or II are disclosed. HET1 --(CH2)n CO2 R (I) ##STR1## Formula I compounds ...
04/30/1991
4994476Dihydropyridin-3,5-dicarboxylates incorporating aryloxypropanolamine moieties
A series of compounds useful in treating cardiovascular disorders due to the combined expression of both ଲ-block and calcium-block activity by these agents. This useful combination of actions is effected by a novel combination of structural subunits...
02/19/1991
4992439Pyridazine carboxylic acids and esters
Heterocyclic acids andesters useful as inhibitors of mammalian blood platelet aggregation characterized by Formula I or II are disclosed. ##STR1## Formula I compounds are those wherein n is 6-9, R is hydrogen, lower alkyl or an alkali metal ion, and ...
02/12/1991
4990344Method for making soluble rice protein concentrate and the product produced therefrom
This invention concerns a process for preparing soluble rice protein concentrate with reduced levels of manganese, aluminum, selenium and phytic acid and improved digestibility from rice raw material comprising: digesting the raw material reduced in particle s...
02/05/1991
4983610Pyrimidine carboxylic acids and esters
Heterocyclic acids and esters useful as inhibitors of mammalian blood platelet aggregation characterized by Formula I are disclosed. HET1 --(CH2)n CO2 R (I) Formula I compounds are those wherein n is 6-...
01/08/1991
4970225Imidazolidine carboxylic acids and esters as blood platelet aggregation inhibitors
Heterocyclic acids and esters useful as inhibitors of mammalian blood platelet aggregation characterized by Formula I are disclosed. HET1 -(CH2)n CO2 R (I) Formula I compounds are those wherein n is 6-...
11/13/1990
4956379Pyrazole carboxylic acids and esters and inhibition of blood platelet aggregation therewith
Heterocyclic acids and esters useful as inhibitors of mammalian blood platelet aggregation characterized by Formula I or II are disclosed. HET1 --(CH2)n CO2 R (I) ##STR1## Formula I compounds ...
09/11/1990
4956376Tetrazole carboxylic acids and esters and inhibition of blood platelet aggregation therewith
Heterocyclic acids and esters useful as inhibitors of mammalian blood platelet aggregation characterized by Formula I or II are disclosed. ##STR1## Formula I compounds are those wherein n is 6-9, R is hydrogen, lower alkyl or an alkali metal ion, and...
09/11/1990
4956182Direct compression cholestyramine tablet and solvent-free coating therefor
A directly compressed cholestyramine tablet with a solvent-free coating is disclosed. The inner core of the tablet is made up of cholestyramine agglomerates consisting of numerous small, irregularly-shaped, jagged-edged fragments having relatively few smo...
09/11/1990
4943573Imidazo[4,5-b]quinolinyloxyalkanoic acid amides with enhanced water solubility
A novel series of 2,3-dihydro-2-oxo-1H-imidazo[4,5-b]quinolinyloxyalkanoic acid amides having enhanced water solubility is disclosed of the formula ##STR1## wherein n is 3 to 5; R1 is alkyl of 1 to 4 carbon atoms; R2 is hydrogen...
07/24/1990
4882472Fluoride supplement calculator
A fluoride supplement calculator utilizes two concentrically positioned relatively rotatable disks. A front disk has a plurality of fluoride level apertures which overlie groups of fluoride dosage amounts carried on the second disk. An age scale is also p...
11/21/1989
4830861Low manganese high protein rice flour
A method for preparing high protein rice flour (HPRF) containing low manganese is disclosed wherein essential steps comprise: blending rice flour and water at a pH of 3.4 to 4.6; separating the insoluble washed rice flour; resuspending the washed rice flour and adj...
05/16/1989
4814455Dihydro-3,5-dicarboxylates
A series of compounds of the 1,4-dihydropyridine class with a 3-carboxylate group linked to an alkyleneaminoalkylene heteroatom have been prepared possessing the general formula ##STR1## wherein R2, R5 and R6 are inde...
03/21/1989
4788862Plastic measuring scoop with foldable handle
A plastic molded measuring scoop assembly includes a generally cylindrical measuring scoop and a hinged handle assembly which is comprised of a fixed inner handle portion and a foldable outer handle portion. The inner handle portion carries a latching cha...
12/06/1988
4775674Imidazoquinolinylether derivatives useful as phosphodiesterase and blood aggregation inhibitors
Novel series of 2,3-dihydro-2-oxo-1H-imidazo[4,5-b]quinolinyl ether derivatives of formula ##STR1## wherein R1 is hydrogen, lower alkly, benzyl; R2 is hydrogen, halogen, lower alkyl, lower alkoxy; Alk is alkylene; Y is hydroxy a...
10/04/1988
4755512Pharmaceutically useful dihydropyridinyldicarboxylate amides and esters incorporating arylpiperazinylalkyl moities
A series of 1,4-dihydropyridin-3,5-yl dicarboxylic acid amides and esters incorporating an arylpiperazinylalkyl moiety have been prepared possessing the general formula ##STR1## wherein R4 is cycloalkyl, aryl or hetaryl, generally with ...
07/05/1988
4701528Intermediates useful in the preparation of 3,4-dihydro-4-oxothieno[2,3-d]pyrimidine-2-carboxylates and process for preparing same
There are disclosed compounds of Formulas I and II: ##STR1## wherein R1 and R2 may be hydrogen, lower alkyl having from 1 to 8 carbon atoms, lower alkenyl having from 3 to 6 carbon atoms, lower alkoxy having from 1 to 6 carbon a...
10/20/1987
47014597-amino-1,3-dihydro-2H-imidazo[4,5-b]quinolin 2-ones and method for inhibiting phosphodiesterase and blood platelet aggregation
Novel series of 2,3-dihydro-2-oxo-1H-imidazo[4,5-b]quinolinyl amine derivatives of Formula ##STR1## wherein R1 is hydrogen, lower alkyl; R2 is hydrogen, lower alkyl, lower alkoxy, halogen; R3 is hydrogen, lower alkyl;...
10/20/1987
4697004Process for preparing low phytate soy protein isolate
A high quality soy protein isolate with significantly reduced aluminum content and substantially free of phytic acid and phytate complexes is prepared by aqueous extraction of defatted particulated soybeans at pH 8 to 10, and at a temperature above 65° C...
09/29/1987
4668686Imidazoquinoline antithrombrogenic cardiotonic agents
Novel series of 1,3-dihydro-2H-imidazo[4,5-b]quinolin-2-ones of the Formula ##STR1## wherein R1 is halogen, lower alkyl, lower alkoxy, trifluoromethyl; R2 is hydrogen, halogen, lower alkyl, lower alkoxy; R3 is hydroge...
05/26/1987
46423456,7-dihydro-3H-imidazo[1,2-a]-purine-9(4H)-ones
Imidazopyrimidinones and other diazaheterocyclopyrimidinones having an additional fused imidazole or triazole ring have utility as bronchodilators, mediator release inhibitors, phosphodiesterase inhibitors, and peripheral vasodilators. They are orally act...
02/10/1987
4640921Treatment of sexual dysfunction with buspirone
Buspirone and its pharmaceutically acceptable salts are useful in treating patients of both sexes suffering from sexual dysfunction....
02/03/1987
4634703Method for alleviation of panic disorders
Buspirone and its pharmaceutically acceptable salts are useful in alleviation of panic disorders which can take the form of clinical syndromes comprising, for example, panic attacks, agoraphobia and phobic anxiety....
01/06/1987
4613600Antidepressant 1,2,4-triazolone compounds
2-[3-[4-(3-Halophenyl)-1-piperazinyl]propyl]-5-(1-hydroxyethyl)-2,4-dihydro -[4-phenoxyalkyl-3H-1,2,4-triazol-3-ones and closely related compounds are psychotropic agents having promise as antidepressants by virtue of their receptor site binding affinity p...
09/23/1986
45968844-(2-phenoxyethyl)-1,2,4-triazolone process intermediates
An improved process for the preparation of 5-ethyl-4-(2-phenoxyethyl)-1,2,4-triazolone, a useful intermediate in the synthesis of antidepressant 1,2,4-triazolones typified by 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-4-(2-phenoxethyl)-2 H...
06/24/1986
4590196Analgesic 1,2-benzisothiazol-3-ylpiperazine derivatives
A series of non-opiate analgesics of Formula I ##STR1## wherein R1 is hydrogen, alkyl, aralkyl, or aryloxyalkyl; R2 is alkyl or hydrogen; and R3 and R4 are independently selected from hydrogen, alkyl, acylo...
05/20/1986
4581357Antipsychotic 5-fluoro-pyrimidin-2-yl piperazine compound
8-[4-[4-(5-Fluoro-pyrimidin-2-yl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decan e-7,9-dione and its pharmaceutically acceptable salts demonstrate antipsychotic activity....
04/08/1986
4537883Lyophilized cyclophosphamide
A lyophilized pharmaceutical solid composition containing cyclophosphamide for reconstitution with water to provide a solution for oral or parenteral administration. This lyophilized cyclophosphamide solid composition demonstrates improved stability, solu...
08/27/1985
45242061-Heteroaryl-4-(2,5-pyrrolidinedion-1-yl)alkyl)piperazine derivatives
Disubstituted N,N'-piperazinyl derivatives are disclosed wherein one substituent is heteroaryl and the other is alkylene attached to the ring nitrogen of substituted 2,5-pyrrolidinedion-1-yl moieties. The substitution pattern of the pyrrolidinedione ring ...
06/18/1985
45171881-Pyrimidinyloxy-3-hetaryl-alkylamino-2-propanols
1-(4-Pyrimidinyloxy)-3-(hetarylalkylamino)-2-propanols are cardiovascular agents having a range of vasodilator and adrenergic beta-receptor blocking activities making these compounds useful anti-hypertensive agents. Preferred compounds bear a hydrazino or...
05/14/1985
4511163Adaptable tip tubing connector
An improved tubing connector with a connecting tip designed to adapt all sizes of tubing commonly employed in nasogastric and gastrostomy feeding. This tubing connector comprises a one-piece hollow unit having at one end a smooth tapered sleeve with an ou...
04/16/1985
4497800Stable liquid diet composition
A nutritionally complete ready-to-use liquid diet for providing total patient nourishment. This diet contains a source of protein equivalent comprised of free amino acids and small peptides; a carbohydrate source comprised of maltodextrin with a dextrose ...
02/05/1985
4463176Process for resolution of optical isomers
A process for resolving a racemic modification of ଲ-adrenergic aryl- or hetaryl-oxypropanolamines such as (&#b1;)-2-[2-hydroxy-3-[[2-(1H-indol-3-yl)-1,1-dimethylethyl]amino]propoxy] benzonitrile into its individual enantiomers is described. The proce...
07/31/1984
4454324Process for production of encainide
An improved process for the preparation of 4-methoxy-2'-{2-(1-methyl-2-piperidyl)ethyl}benzanilide has been developed. The process comprises essentially three steps starting with methyl anthranilate and 2-picoline and features a novel low-pressure hy...
06/12/1984
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