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| Number | Title | Issue Date |
| 7863427 | Immunoassays for buprenorphine and norbuprenorphine Methods, compositions and kits are disclosed directed at haptens, immunogens and immnoassays for buprenorphine (BUP) and nor buprenorphine (norBUP). The method comprises providing in combination in a medium (i) a sample suspected of containing buprenorphine (BUP) or... | 01/04/2011 |
| 7279340 | Synthesis and application of procainamide analogs for use in an immunoassay The present invention relates to immobilized procainamide analogs, as well as to a method of making immobilized procainamide analogs. These immobilized analogs are prepared by activating the carboxyl group on a substituted p-benzoic acid derivative toward nucleophil... | 10/09/2007 |
| 7220842 | Immunoassays for buprenorphine and norbuprenorphine Methods, compositions and kits are disclosed directed at haptens, immunogens and immunoassays for buprenorphine (BUP) and nor buprenorphine (norBUP). The method comprises providing in combination in a medium (i) a sample suspected of containing buprenorphine (BUP) o... | 05/22/2007 |
| 7186518 | Method and composition useful for determining FK 506 New derivatives of FK 506 are disclosed. These new derivatives and other derivatives that are useful for determining the levels of FK 506 in a sample are also provided as are assay procedures and kits for use in determining the levels of FK 506 or other macrophilin ... | 03/06/2007 |
| 6949524 | Polysaccharide conjugates of biomolecules Compounds that are modified polysaccharides having pendant aldehyde functionalities are disclosed. Each of the aldehyde functionalities is attached through a linker to a position corresponding to a hydrogen atom of a different hydroxyl group of unmodified polysaccha... | 09/27/2005 |
| 6887669 | Reagents for assays for ligands The present invention relates to a method for releasing a ligand from a complex of the ligand with an endogenous protein using a releasing agent. ... | 05/03/2005 |
| 6783947 | Protecting groups for biological labeling Alpha-haloketones are useful alkylating agents for coupling to sulfhydryl-containing biomolecules. However, they react spontaneously with water, alkali and organic bases and therefore cannot be stored for extended periods of time in aqueous solutions, particularly i... | 08/31/2004 |
| 6706861 | Reconstitution of purified membrane proteins into preformed liposomes The present application relates to a method of making liposomes having membrane proteins incorporated therein, the method comprising: providing the membrane protein in solution; providing a solution of preformed liposomes; and incubating the mixture. Prior to the st... | 03/16/2004 |
| 6596543 | Use of liposomes of defined composition and size for the preparation of prothrombin time reagents The present invention relates generally to the field of prothrombin time reagents for determining dysfunction in the coagulation system and more specifically to reagents made from native thromboplastin or purified or recombinant tissue factor and phosphol... | 07/22/2003 |
| 6013531 | Method to use fluorescent magnetic polymer particles as markers in an immunoassay This invention provides a novel process of using magnetically responsive fluorescent polymer particles comprising polymeric core particles coated evenly with a layer of polymer containing magnetically responsive metal oxide as highly sensitive quantitativ... | 01/11/2000 |
| 5766872 | Method for eliminating hemolysis interference in an amylase analysis A method for increasing the accuracy of photometric-based assays for -amylase by subjecting a sample to a secondary interrogating beam of radiation at a wavelength distinguishable from a primary interrogating beam of radiation. The secondary interr... | 06/16/1998 |
| 5747268 | Tumor marker control The present invention provides a stable control serum or plasma for tumor diagnosis, wherein the control contains the tumor markers relevant for the diagnosis of tumors. The serum or plasma has a reduced lipid content. The present invention also provides ... | 05/05/1998 |
| 5747240 | Epitope mapping of the c33 region of HCV An assay for detection of serum antibodies having specificity to hepatitis C viral antigens utilizes the carboxy-terminal 102 amino acids of the c33c region of nonstructural gene 3 of HCV containing substantially all the epitopes of the gene 3 protein. In... | 05/05/1998 |
| 5702912 | Method to determine the concentration of anticoagulants The present invention relates to a method to determine the concentration of anticoagulants as a function of the inhibition of thrombin formation in an assay mixture. The assay mixture is composed of two reagents and the diluted plasma sample. The diluted ... | 12/30/1997 |
| 5635346 | Assay for Non-A Non-B hepatitis New assays for diagnosing NANBH utilizing novel peptide fragments derived from polypeptide antigens reactive to antibodies present in the sera of infected patients are disclosed. In producing these peptides, the portion of the polypeptide contributing to ... | 06/03/1997 |
| 5589327 | Method and composition for the determination of red blood cell floate A composition is described which is useful in the assay of folate from a hemolysate prepared from red blood cells using non-radiolabeled assay techniques such as fluorometric, colorimetric, enzymatic or chemiluminescent assay methods. Methods to ready hem... | 12/31/1996 |
| 5565328 | Measurement of color reactions by monitoring a change of fluorescence The present invention relates to a method to determine the concentration of an unknown substance in a colorimetric reaction using a fluorometric reader. The change in color can be monitored by observing the change of fluorescence of a known amount of a su... | 10/15/1996 |
| 5504193 | Extraction methods for preparing thromboplastin reagents The Prothrombin Time (PT) is used as a screening test for blood coagulation factor deficiencies and for monitoring oral anti-coagulant therapy using coumadin. Thromboplastin reagents activate the extrinsic pathway of coagulation and are the basis for the ... | 04/02/1996 |
