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| Number | Title | Issue Date |
| 5387673 | Active fragments of fibroblast growth factor The present invention relates to novel fragments of basic fibroblast growth factor (bFGF). The mitogenic potency of one of these bFGF fragments, identified as HBF-2 is about 25-50 fold less than that of native bFGF but at least 103 -104 | 02/07/1995 |
| 5384259 | Construct and method for expression of tetracycline resistance genes in E. Coli The present invention relates to DNA sequences useful in directing low to moderate expression of proteins in E. coli. The sequences are on based on modification of the repressor binding site of the tetA gene of transposon Tn10.... | 01/24/1995 |
| 5371206 | DNA encoding chimeric fibroblast growth factors The present invention relates to novel chimeric fibroblast growth factors (FGF) wherein the alanine at amino acid 3 and serine 5 of native human recombinant basic fibroblast growth factor are replaced with glutamic acid. The N-terminus sequence of the pre... | 12/06/1994 |
| 5338664 | Assay for detection of bacterial iron transport inhibitors The present invention relates to a method for identifying a TonB inhibitor in a test sample comprising: (a) growing a TonB+ microorganism in the presence of the test sample and a lethal agent, the activity of which is mediated by TonB; (b) identifyi... | 08/16/1994 |
| 5336488 | Method of treating or preventing mastitis in animals with involuting mammary glands by administering recombinant cytokines Cytokines are useful for the ability to improve the natural defense system of the involuting mammary gland. In addition to the immunopotentiating activity, cytokines accelerate the normal physiology of involution of the mammary gland and thereby afford fu... | 08/09/1994 |
| 5334521 | Cloning and characterization of a cardiac adenylyl cyclase A DNA sequence encoding a novel effector enzyme referred to as a cardiac adenylyl cyclase is described. The amino acid sequence of the cardiac adenylyl cyclase encoded by that DNA sequence is also described.... | 08/02/1994 |
| 5334379 | Cytokine and hormone carriers for conjugate vaccines This invention pertains to immunogenic conjugates comprising a carbohydrate containing antigen or other antigen bound to or genetically fused with a cytokine, lymphokine, hormone or growth factor having immunomodulating activity, wherein the cytokine, lym... | 08/02/1994 |
| 5331094 | Purified active somatostatin receptor The invention relates to a purified somatostatin receptor which is purified at least about 30,000-fold over the receptor which is membrane-bound. The invention also provides pharmaceutical compositions containing the receptor and antibodies to the recepto... | 07/19/1994 |
| 5317030 | Method and compositions for helmintic, arthropod ectoparasitic and acaridal infections with novel agents The present invention relates to methods and compositions for the control and prevention of helmintic, arthropod ectoparasitic and acaridal infections, in warm-blooded animals, such as meat-producing animals, and poultry, by administering to said animals ... | 05/31/1994 |
| 5310882 | Somatotropins with alterations in the -helix 3 region The present invention relates to somatotropin analogues with amino acid changes in the -helix 3 regions of said somatotropins, changes in the -helix 2 regions, combinations thereof plus combinations with other changes to the native amino aci... | 05/10/1994 |
| 5310883 | Chimeric fibroblast growth factors The present invention relates to novel chimeric fibroblast growth factors (FGF) wherein the alanine at amino acid 3 and serine 5 of native human recombinant basic fibroblast growth factor are replaced with glutamic acid. The N-terminus sequence of the pre... | 05/10/1994 |
| 5302702 | Chimeric fibroblast growth factors The present invention relates to novel chimeric fibroblast growth factors (FGF) wherein the alanine at amino acid 3 and serine 5 of native human recombinant basic fibroblast growth factor are replaced with glutamic acid. The N-terminus sequence of the pre... | 04/12/1994 |
| 5206354 | DNA sequence encoding active fragment of fibroblast growth factor, HBF-2 The present invention relates to novel fragments of basic fibroblast growth factor (bFGF). The mitogenic potency of one of these bFGF fragments, identified as HBF-2 is about 25-50 fold less than that of native bFGF but at least 103 -104 | 04/27/1993 |
| 5198464 | Method and compositions for helmintic, arthropod ectoparasitic and acaridal infections with novel agents The present invention relates to methods and compositions for the control and prevention of helmintic, arthropod ectoparasitic and acaridal infections, in warm-blooded animals, such as meat-producing animals, and poultry, by administering to said animals ... | 03/30/1993 |
| 5169956 | Macrolide antibiotic compounds This invention relates to new agents designated LL-F28249, LL-F28249ଲ, LL-F28249γ, LL-F28249δ, LL-F28249&3xb5;, LL-F28249.zeta., LL-F28249η, LL-F28249θ, LL-F28249.iota., LL-F28249.kappa., LL-F28249λ, LL-F28249μ, LL-F28249.nu., and ... | 12/08/1992 |
| 5106994 | Agents and method of production thereof This invention relates to new agents designated LL-F28249, LL-F28249ଲ, LL-F28249γ, LL-F28249δ, LLF28249&3xb5;, LL-F28249.zeta., LL-F28249η, LL-F28249θ, LL-F28249.iota., LL-F28249.kappa., LL-F28249λ, LL-F28249μ, LL-F28249.nu., and L... | 04/21/1992 |
| 5106631 | Cheese production The present invention relates to methods for improving cheese production by utilizing plasmin-regulating agents to maintain milk plasmin concentration in milk used to make cheese at that found at early lactation or at less than 0.2 mg/l milk.... | 04/21/1992 |
| 5064943 | Method for solubilization and naturation of somatotropin A method for solubilization and naturation of somatotropin using an aqueous alkaline solution results in lower dimer formation and eliminates denaturants and separate renaturation steps and agents.... | 11/12/1991 |
| 5019589 | Ɗ23 -LL-F28249 compounds The present invention relates to novel derivatives of LL-F28249 compounds wherein the 23-hydroxy group is eliminated to introduce a double bond at the 23,24 position. These resulting derivatives are Ɗ23 -LL-F28249 compounds. These LL-F28249 pr... | 05/28/1991 |
| 4983525 | Plasmids derived from actinomadura species Plasmid DNA was isolated from two Actinomadura species and characterized by mapping the sites of restriction endonuclease cleavages and by calculation of total molecular size.... | 01/08/1991 |
| 4956479 | 23-deoxy-27-chloro derivatives of LL-F28249 compounds The present invention relates to novel derivatives of LL-F28249 compounds. These LL-F28249 compounds preferably are derived via a controlled microbiological fermentation of Streptomyces cyaneogriseus subspecies noncyanogenus having deposit accession numbe... | 09/11/1990 |
| 4929608 | Emulsifiable concentrates of malathion The present invention relates to emulsifiable concentrate compositions of phosphorodithioates, especially [S-1,2-bis-(ethoxycarbonyl)ethyl] O,O-dimethylphosphorodithioate, known as malathion insecticide, containing vegetable oils as the solvent. These com... | 05/29/1990 |
| 4916154 | 23-Imino derivatives of LL-F28249 compounds The present invention relates to novel 23-imino derivatives of LL-F28249, ଲ, γ, δ, &3xb5;, .zeta., θ, .iota., and λ compounds. These LL-F28249 compounds (collectively) are isolates from the fermentation broth of Streptomyces cyaneogrisesu... | 04/10/1990 |
| 4892707 | Apparatus for the calorimetry of chemical processes A calorimeter for measuring the thermodynamic and kinetic characteristics of chemical reactions, microbial fermentations, and other processes of industrial importance is described. The present invention also relates to a method of operation of this appara... | 01/09/1990 |
| 4886830 | Mono- and diepoxide derivatives of 23-deoxyl-LL-F28249 compounds The present invention relates to novel derivatives of LL-F28249 compounds wherein the 23-hydroxyl group is replaced with hydrogen and the double bond at the C(26,27)-position is epoxidized concomitant with or without epoxidation of the double bond at the ... | 12/12/1989 |
| 4886829 | 23-Oxo (keto) and 23-imino derivatives of mono- and diepoxy LL-F28249 compounds The present invention relates to novel 23-oxo (keto) and 23-imino derivatives of certain C(26,27)-epoxy- and C(14,15;26,27)-diepoxy-LL-F28249 compounds. The LL-F28249 compounds (collectively) are isolates from the fermentation broth of Streptomyces c... | 12/12/1989 |
| 4886828 | Ɗ22 -derivatives of LL-F28249 compounds The present invention relates to novel derivatives of LL-F28249 compounds. These LL-F28249 compounds preferably are derived via a controlled microbiological fermentation of Streptomyces cyaneogriseus subsp. non-cyanogenus having deposit accession numer NR... | 12/12/1989 |
| 4877888 | 13-deoxy-23-imino derivatives of 13-deoxy C-076-aglycone compounds The present invention relates to novel 23-imino derivatives of C-076 wherein the C-076 compounds are not substituted at the 13-position. The C-076 compounds (collectively) are isolates from the fermentation broth of Streptomyces avermitilis. The precursor... | 10/31/1989 |
| 4876272 | Mono- and diepoxide derivatives of LL-F28249 compounds The present invention relates to novel mono- C(26,27) and diepoxide C(14,15;26,27) derivatives of LL-F28249, ଲ, &3xb5;, .zeta., θ and .iota. compounds. The LL-F28249 compounds (collectively) are isolates from the fermentation broth of Strept... | 10/24/1989 |
| 4875929 | Aqueous suspension concentrate compositions The present invention relates to novel stable aqueous suspension concentrate or aqueous flowable compositions of the low-melting dinitroaniline pesticide, pendimethalin, alone or in combination with secondary pesticide(s) melting at temperatures greater t... | 10/24/1989 |
| 4871392 | Aqueous suspension concentrate compositions of pendimethalin The present invention relates to novel stable aqueous suspension concentrate compositions of the low-melting pesticide pendimethalin, alone or in combination with secondary pesticides which are water soluble or have melting points greater than 70° C. The... | 10/03/1989 |
| 4869901 | Method and compositions for helmintic, arthropod ectoparasitic and acaridal infections with novel agents The present invention relates to methods and compositions for the control and prevention of helmintic, arthropod ectoparasitic and acaridal infections, in warm-blooded animals, such as meat-producing animals, and poultry, by administering to said animals ... | 09/26/1989 |
| 4857544 | 27-Halo derivatives of LL-F28249 compounds The present invention relates to novel derivatives of LL-F28249 compounds wherein the pendent C(26,27) olefinic group at C(25) is converted into a 27-bromo or 27-chloro-26-methylene group. The 27-bromo compounds are derived by reacting the LL-F28249 compo... | 08/15/1989 |
| 4851428 | Mono- and diepoxide derivatives of Ɗ22-LL-F28249 compounds The present invention relates to novel derivatives of LL-F28249 compounds wherein the 23-hydroxyl group is eliminated to form a double bond at the C(22,23)-position (Ɗ22), and the double bond at the C(26,27)-position is epoxidized concomitant ... | 07/25/1989 |
| 4849446 | 23-imino derivatives of 23-keto compounds The present invention relates to novel 23-imino derivatives of the compounds collectively referred to as 23-keto C-076 compounds. The C-076 compounds (collectively) are isolates from the fermentation broth of Streptomyces avermitilis. These novel compound... | 07/18/1989 |
| 4847405 | Method for the preparation of anilinofumarate [quinoline-2,3- dicarboxylic] The present invention relates to novel methods for the preparation of anilinofumarate [quinoline- 2,3-dicarboxylic acid], a useful intermediate in the preparation of 2-(2-imidazolin-2-yl)-quinoline-3-carboxylic acid herbicidal agents.... | 07/11/1989 |
| 4814349 | Insecticidal substituted and unsubstituted benzoic acid 1-alkyl, 2 alkyl and 2-cycloalkylhydrazides The present invention relates to methods for controlling insect populations and for protecting living plants from insect attack by applying to said plants or to the soil in which they are growin an insecticidally-effective amount of a substituted benzoic ... | 03/21/1989 |
| 4814486 | Method for the preparation of anilinofumarate The present invention relates to an improved method for the preparation of anilinofumarates useful as intermediates in the preparation of 2-(2-imidazolin-2-yl) quinoline-3-carboxylic acid herbicidal agents.... | 03/21/1989 |
| 4786632 | Emulsifiable concentrates of malathion with inherent low eye-irritation properties Emulsifiable concentrates of malathion having low eye irritation properties. Compositions of the invention yield stable emulsions when diluted with water.... | 11/22/1988 |
| 4775693 | Method for controlling insects and acarina with the use of cinnamamide compounds The present invention relates to novel cinnamamide compounds and a process for the preparation thereof. The compounds of the invention are useful for controlling insects and acarina.... | 10/04/1988 |
