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...that the x-ray was discovered purely by accident? When German physicist Wilhelm Konrad von Roentgen was experimenting with cathode rays in 1895, he put an activated Crookes tube in a book and went out to lunch. When he returned, he discovered that a key that had also been placed in the book showed up as an image on the developed film!

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Attorney: Trecartin; Richard F.


Number of patents: 119
Last date: May 22, 2012

1      
NumberTitleIssue Date
8182679Organosilanes and substrate bonded with same
The present invention, provides novel silicon compounds, methods for making these novel silicon compounds, compositions comprising these novel silicon compounds attached to substrates, methods for attaching the novel silicon compounds to substrates and methods for u...
05/22/2012
8155413Method and system for analyzing skin conditions using digital images
The embodiments of the present invention include a method and system for analyzing skin conditions using digital images. The method comprises acquiring a white-light image and an ultraviolet (UV) image of a portion of a body surface, such as a person's face, each of...
04/10/2012
8131029Systems and methods for automatic skin-based identification of people using digital images
Systems and methods are provided for automatic identification of a person based on an analysis of the person's skin. In one embodiment, a method for automatically identifying a person comprises acquiring white-light and UV images of a portion of the person's skin, g...
03/06/2012
8088968Transgenic animals for analyzing CYP3A4 cytochrome P450 gene regulation
The invention relates to the generation of non-human transgenic animals comprising a reporter construct for producing a detectable amount of a reporter molecule operably linked to a transcriptional regulatory nucleic acid molecule from the human CYP3A4 gene located ...
01/03/2012
8017173Dehydrated mash potato product and process
Dehydrated potato pellets are made by preparing an aqueous mixture of dried potato pieces, an emulsifier, and oil, and, optionally, a freshly cooked potato, homogenizing the mixture to produce a pumpable, flowable aqueous dispersion, mixing the dispersion with more ...
09/13/2011
7906491Compounds for modulating the activity of exchange proteins directly activated by cAMP (Epacs)
The present invention relates to novel compounds for modulating the activity of exchange proteins directly activated by cAMP (Epacs). In particular, the present invention relates to cAMP analogues that specifically modulate the activity of Epacs. Examples of the com...
03/15/2011
7879385Emulsified bean-based oil substitute
A method for making a bean-based oil substitute comprising the steps of making an aqueous liquid dispersion of comminuted beans in a stable flowable form, homogenizing said aqueous dispersion, and mixing an emulsifier with said comminuted beans before, during or aft...
02/01/2011
7840064Method and system for automatic identification using digital images
The present invention provides a method for automatically identifying a person comprises acquiring white-light and UV images of a portion of the person's skin, generating a skin mask from the white-light image, and comparing the skin mask with a pre-stored skin mask...
11/23/2010
7800297Nanostructured electroluminescent device and display
An electroluminescent device contains (1) first and second electrodes, at least one of which is transparent to radiation; (2) a hole conducting layer containing first nanoparticles wherein the hole conducting layer is in contact with said first electrode; (3) an ele...
09/21/2010
7799350Use of cytokines and mitogens to inhibit graft versus host disease
A method for inducing T cell tolerance in peripheral blood mononuclear cells (PBMCs) comprising adding a suppressive composition to said cells. ...
09/21/2010
7683050Formulations and methods of administration of cephalotaxines, including homoharringtonine
The present invention is directed to compositions and methods for the treatment of patients with cephalotaxines, for example, homoharringtonine. The invention is also directed to improvements in the purity, manufacturing process, formulation and administration of ho...
03/23/2010
7642252Angiogenesis inhibition by cephalotaxine alkaloids, derivatives, compositions and uses thereof
The invention relates to compositions and methods useful in treating or preventing angiogenic disease. The invention provides for compositions comprising cephalotaxine alkaloids as antiangiogenic agents for treatment of a host with an angiogenic disease or for proph...
01/05/2010
7572535Ion conductive copolymers containing one or more hydrophobic oligomers
In one aspect, the invention provides ion conductive copolymers comprising (1) a plurality of first oligomers, (2) a plurality of second oligomers, (3) ion conductive monomers and (4) linking monomers. The oligomers preferably are hydrophobic and together with the i...
08/11/2009
7531712P450 gene regulation
The invention relates to the generation of non-human transgenic animals comprising a reporter construct for producing a detectable amount of a reporter molecule operably linked to a transcriptional regulatory nucleic acid molecule from the human CYP3A4 gene located ...
05/12/2009
7507842Cyclic nitro compounds, pharmaceutical compositions thereof and uses thereof
The present invention provides cyclic nitro compound, pharmaceutical compositions of cyclic nitro compounds and methods of using cyclic nitro compounds and/or pharmaceutical compositions thereof to treat or prevent diseases or disorders characterized by abnormal cel...
03/24/2009
7477767Systems and methods for analyzing skin conditions of people using digital images
Systems and methods are provided for analyzing skin conditions using digital images. The method comprises acquiring a white-light image and an ultraviolet (“UV”) image of at least a portion of a body surface, such as a person's face, each of the white-light and ...
01/13/2009
7454046Method and system for analyzing skin conditions using digital images
The embodiments of the present invention include a method and system for analyzing skin conditions using digital images. The method comprises acquiring a white-light image and an ultraviolet (UV) image of a portion of a body surface, such as a person's face, each of...
11/18/2008
7452675Methods of screening for TRPM4b modulators
The invention relates, in part, to methods useful in identifying molecules, that bind TRPM4b, which modulate TRPM4b ion channel activity, and/or which alter expression of TRPM4b within cells. The TRPM4b channels as described herein contai...
11/18/2008
7433764Method and system for recording a traffic violation committed by a vehicle
The invention relates to a method for recording a traffic violation in which a vehicle is involved, by detecting the violation, making a record of the violation, and searching for and reading from the record a license plate of the vehicle involved in the violation. ...
10/07/2008
7405676Method and system for detecting with laser the passage by a vehicle of a point for monitoring on a road
The invention relates to a method for detecting the passage by a vehicle of a determined point for monitoring on a road, wherein from a remotely situated location a laser beam is transmitted continuously to the point for monitoring, reflections from the transmitted ...
07/29/2008
7381563Use of cytokines and mitogens to inhibit graft versus host disease
The field of the invention is generally related to pharmaceutical agents useful in treating graft-versus-host disease (GVHD) in patents that have received allogenic bone marrow transplants. ...
06/03/2008
7300663Adhesion and sealing of tissue with compositions containing polyfunctional crosslinking agents and protein polymers
Proteinaceous polymers having repetitive units from naturally occurring structural proteins are employed as backbones for functionalities for crosslinking to provide strongly adherent tissue adhesives and sealants. Particularly, block copolymers of elastin and fibro...
11/27/2007
7285580Methods of using primer molecules for enhancing the mechanical performance of tissue adhesives and sealants
The present invention concerns novel methods for enhancing the mechanical performance of tissue adhesives and sealants which comprises employing a primer molecule in association with a tissue adhesive or sealant, wherein the primer molecule serves to enhance the str...
10/23/2007
7238321Method for rapid thermal cycling of biological samples
A thermal cycling method and device is disclosed. The device comprises a sample chamber whose temperature can be rapidly and accurately modulated over a range of temperatures needed to carry out a number of biological procedures, such a DNA polymerase chain reaction...
07/03/2007
7220703Tethered polymer ligands
This invention relates to improved porous solid supports for chromatography and catalysis. The supports are prepared by covalently binding a tether polymer to a solid support, and then blocking the remainder of the support surface with a blocking reagent. The tether...
05/22/2007
7201844Composite matrices with interstital polymer networks
The present invention relates in general to the preparation and use of matrices having solid spaces, interstitial spaces and interstitial polymer networks. In particular, the interstitial polymer networks have utility in chemical and biochemical separations, solid p...
04/10/2007
7202001Sulfonated copolymer
This invention relates to sulfonated copolymers which are useful in forming polymer electrolyte membranes used in fuel cells. ...
04/10/2007
7190306Method and system for detecting with radar the passage by a vehicle of a point for monitoring on a road
The invention relates to a method for detecting the passage by a vehicle of a determined point for monitoring on a road, wherein from a remotely situated location a radar beam is transmitted continuously to the point for monitoring, reflections from the transmitted ...
03/13/2007
7158903Methods for quantitative analysis by tandem mass spectrometry
The present invention provides methods for high throughput analysis of analytes in complex mixtures for unresolved chromatographic peaks including specific embodiment for summing intensities for each mass transition of interest over a selected chromatographic peak (...
01/02/2007
7138248Method of inhibiting inward rectifier, G-protein activated, mammalian, potassium channels and uses thereof
Compositions and methods are provided for producing functional mammalian inward rectifier, G-protein activated potassium channels (Kir3.0 channels). A channel is a multimeric protein comprising one or more Kir3.0 polypeptides, e.g. Kir3.1, Kir3.2, etc., where the po...
11/21/2006
7135481Naphthalimide compositions and uses thereof
Methods of treating a solid tumor are disclosed comprising administering amonafide in combination with an antiproliferative agent. ...
11/14/2006
7115259Use of cytokines and mitogens to inhibit pathological immune responses
The invention is generally related to methods of treating autoimmune diseases, including both antibody-mediated and cell-mediated disorders. ...
10/03/2006
7094490Ion conductive block copolymers
This invention relates to ion conductive copolymers which are useful in forming polymer electrolyte membranes used in fuel cells. ...
08/22/2006
7083916DNA encoding inward rectifier, G-protein activated, mammalian, potassium KGA channel and uses thereof
This invention provides isolated nucleic acid molecules which encode inward rectifier, G-protein activated, mammalian, potassium KGA channel. This invention also provides a nucleic acid molecule of at least 15 nucleotides capable of specifically hybridizing with the...
08/01/2006
7074762Composition and method for improving function of embryonic kidney transplants
A method and composition for enhancing the development of metanephric tissue upon transplantation into an allogenic or xenogenic host are disclosed. Metanephric tissue is removed from an embryonic donor and is contacted with a composition comprising one or more grow...
07/11/2006
7060727Prodrugs of fused GABA analogs, pharmaceutical compositions and uses thereof
The present invention relates generally to prodrugs of fused GABA analogs, pharmaceutical compositions of prodrugs of fused GABA analogs, methods of making prodrugs of fused GABA analogs and methods of using prodrugs of fused GABA analogs and pharmaceutical composit...
06/13/2006
7045685Insect viruses and their uses in protecting plants
The present invention relates to an isolated small RNA virus capable of infecting insect species including Heliothis species, and to the nucleotide sequences and proteins encoded thereby. The invention contemplates uses of the virus in controlling insect atta...
05/16/2006
7033799Haemophilus adherence and penetration proteins
Haemophilus adhesion and penetration proteins, nucleic acids, vaccines and monoclonal antibodies are provided. ...
04/25/2006
6994967Transcription factor regulators and methods for screening for same
Described herein are methods of expression cloning of components of signaling pathways that activate a transcription factor of interest. The methods are efficient for identifying modulators of transcription factors. The modulators can then be screened further or use...
02/07/2006
6962686Cell-specific gene delivery vehicles
A delivery vehicle is described that is capable of being specifically bound to and taken into targeted cells, delivering numerous physiological agents, particularly paramagnetic ions for magnetic resonance imaging (MRI) of the cells. The delivery vehicle comprises a...
11/08/2005
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