"That the automobile has practically reached the limit of its development is suggested by the fact that during the past year no improvements of a radical nature have been introduced."
Scientific American ; Jan. 2 edition, 1909
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| Number | Title | Issue Date |
| 7595398 | N-(5-membered aromatic ring)-amido anti-viral compounds Disclosed are compounds having Formula (I) and the compositions and methods thereof for treating or preventing a viral infection mediated at least in part by a virus in the Flaviviridae family of viruses, wherein A, R2, m, R, V, W, T, Z, R1, Y,... | 09/29/2009 |
| 7534893 | Imidazol-2-one compounds useful in the treatment of various disorders A compound of formula (I) wherein: R is a group selected from: A-B is a bivalent radical of formula (v), (vi) or (vii) —CH═C(R11 | 05/19/2009 |
| 7482374 | Pyrrolidine-2-ones as Factor Xa inhibitors The invention relates to compounds of formula (I): wherein substituents are as defined. ... | 01/27/2009 |
| 7482365 | Piperidylcarboxamide derivatives and their use in the treatment of tachykinin-mediated diseases The present invention relates to piperidine derivatives of formula (I): wherein R, R1, R2, R3, R4, R5, R6, X, Y, m and n are as defined herein; and pharmaceu... | 01/27/2009 |
| 7446222 | Phenyl compounds Compounds of formula (I) or derivatives thereof: wherein A, B, Z, R1, R2a, R2b, Rx, R8, and R9 are as defined in the specification, a process for the prepara... | 11/04/2008 |
| 7429587 | Pyrrolidine derivatives as factor Xa inhibitors The invention relates to compounds of formula (I) processes for their preparation, pharmaceutical compositions containing them and to their use in medicine, particularly use in the amelioration of a clinical condition for w... | 09/30/2008 |
| 7375235 | Process for preparing substituted benzimidazole compounds The invention relates to new methods of preparing substituted benzimidazole compounds, such as 2-bromo-5,6-dichlorobenzimidazole, which are useful in the preparation of compounds having antiviral activity. ... | 05/20/2008 |
| 7112670 | Crystal form The present invention involves a novel crystal form of 17β-hydroxy-7α-(5′-methyl-2′-furyl)-pregna-4,9(11)-dien-3-one-21-carboxylic acid, γ-lactone, having the formula which is an intermediate useful in pre... | 09/26/2006 |