Quotables
"There is no likelihood man can ever tap the power of the atom."
Robert Millikan, Nobel Prize winner in physics
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 5587485 | Heterocyclic- and carbocyclic- substituted benzoic acids and synthesis thereof The disclosure herein relates to the title compounds and synthesis thereof by catalytic oxidation of the corresponding alkyl-substituted phenylheterocyclic or carboxylic compound.... | 12/24/1996 |
| 5482974 | Selected fungicides for the control of take-all disease of plants A compound for controlling Take-all disease of plants by applying, preferably to the seed prior to planting, a fungicide of the formula ##STR1## wherein R2 is ethyl, iso-propyl, propyl or allyl; A is N(CH3)1-n Hn... | 01/09/1996 |
| 5145845 | Substituted 2-carboxylindoles having pharmaceutical activity The present invention relates to novel compounds, which are derivatives of ureas, thioureas, carbamates, sulfonylureas, sulfonamides, amides, and thioamides of 2-carboxyindoles as illustrated by the formula ##STR1## The invention also relates to meth... | 09/08/1992 |
| 5143929 | 2-substituted thiazolidinone, oxazolidinone, and imidazolidinone derivatives of fenamates as antiinflammatory agents The present invention is for selected novel compounds which are 2-substituted thiazolidinone, oxazolidinone, and imidazolidinone derivatives of fenamates, as well as pharmaceutical compositions and methods of use thereof. These compounds exhibit activity ... | 09/01/1992 |
| 5143927 | 3-(thiazolidone, oxazolidinone, imidazolidinone)-indoles as antiinflammatory agents The present invention is for selected novel compounds which are 3-[thiazolidinone, oxazolidinone, imidazolidinone]-indoles as well as pharmaceutical compositions and methods of use thereof. These compounds have activity useful in treating allergies and in... | 09/01/1992 |
| 5143928 | 3,5-di-tertiarybutyl-4-hydroxyphenylmethylene derivatives of 2-substituted thiazolidinones, oxazolidinones, and imidazolidinones as antiinflammatory agents The novel 3,5-ditertiarybutyl-4-hydroxy-phenylmethylene derivative of 2-substituted thiazolidinones, oxazolidinones, and imidazolidinones as antiinflammatory agents having inhibiting activity for 5-lipoxygenase, cyclooxygenase, or both.... | 09/01/1992 |
| 5142095 | Diarylalkanoids having activity as lipoxygenase inhibitors The present invention is novel diarylalkanoids having activity as lipoxygenase inhibitors, novel pharmaceutical compositions therefor, and novel methods of use in treating asthma, allergies, cardiovascular diseases, migraines, psoriasis and immunoinflamma... | 08/25/1992 |
| 5124347 | 3-5-ditertiarybutylphenyl-4-hydroxymethylidene derivatives of 1,3-dihydro-2H-indole-2-ones as antiinflammatory agents The present invention is for selected novel compounds which are indoles substituted at the 3-position with [3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene as well as pharmaceutical compositions and methods of use thereof. These compounds have a... | 06/23/1992 |
| 5102897 | 3,5-ditertiarybutyl-4-hydroxyphenyl, 1,3,4-thiadiazoles and oxadiazoles linked by carbon, oxygen, and sulfur residues The novel 3,5-ditertiarybutyl-4-hydroxyphenylthio-1,3,4-thiadiazoles and oxadiazoles and 3,5-ditertiarybutyl-4-hydroxyphenylmethanone-1,3,4-thiadiazoles and oxadiazoles and related compounds of the present invention are antiinflammatory agents having... | 04/07/1992 |
| 5102879 | Method of treating gout with novel 9-deazaguanines The present invention is novel derivatives of pyrrolo[3,2-d]pyrimidines and pharmaceutical compositions and methods of use therefor. The derivatives are inhibitors of purine nucleoside phosphorylase selectively cytotoxic to T-cells but not to B-cells in t... | 04/07/1992 |
| 5101030 | 9-deazaguanines The present invention is novel derivatives of pyrrolo [3,2-d]pyrimidines and pharmaceutical compositions and methods of use therefor. The derivatives are inhibitors of purine nucleoside phosphorylase selectively cytotoxic to T-cells but not to B-cells in ... | 03/31/1992 |
| 5098905 | 7-deazaguanines as immunomodulators The present invention is various 7-deazaguanines having activity as immunomodulators. Also included are pharmaceutical compositions and methods of use thereof.... | 03/24/1992 |
| 5098906 | Purine derivatives Novel purine derivatives are described as agents for treating autoimmune diseases as well as a method of manufacture and pharmaceutical compositions as well as novel intermediates in the manufacture thereof.... | 03/24/1992 |
| 5086064 | 3,5-di-tertiary-butyl-4-hydroxyphenyl thiazolyl, oxazolyl, and imidazolyl methanones and related compounds as antiinflammatory agents The novel 3,5-di-tertiary-butyl-4-hydroxyphenylthiazolyl, -oxazolyl, or -imidazolyl methanones and methanone oximes of the present invention are antiinflammatory agents having activity as inhibitors of 5-lipoxygenase, cyclooxygenase or both.... | 02/04/1992 |
| 5077411 | Dairylalkanoids having activity as lipoxygenase inhibitors The present invention is novel diarylalkanoids having activity as lipoxygenase inhibitors, novel pharmaceutical compositions therefor, and novel methods of use in treating asthma, allergies, cardiovascular diseases, migrains, psoriasis and immunoinflammat... | 12/31/1991 |
| 5075330 | N-hydroxyamide, N-hydroxythioamide, N-hydroxyurea, and N-hydroxythiourea derivatives of selected NSAIDS as antiinflammatory agents The present invention includes N-hydroxyamide, N-hydroxyurea, N-hydroxythioamide, and N-hydroxythiourea derivatives of fenamates, indomethacin, cicloprofen, oxepinac, and indoprofen as dual inhibitors or selective ihibitors of cyclooxygenase and 5-lipoxyg... | 12/24/1991 |
| 5073639 | Process for the synthesis of novel and known nitroimidazoles which are useful as sensitizing agents The present invention is a novel process for preparing both known and novel nitroimidazoles having novel intermediates. The process advantageously reduces the number of process steps, provides increased yield with both greater safety and greater control o... | 12/17/1991 |
| 5068110 | Stabilization of enteric coated dosage form The present invention is a stabilized enteric-coated pharmaceutical dosage form and processes for the preparation thereof. Dissolution stability after storage of the dosage form under high stress conditions is improved by an enteric-coated dosage form hav... | 11/26/1991 |
| 5066668 | Triazole derivatives of fenamates as antiinflammatory agents The present invention is novel compounds which are 1,2,4-triazoles, derivatives of fenamates and pharmaceutically acceptable additions and base salts thereof, pharmaceutical compositions and methods of use therefor. The nvention compounds are now found to... | 11/19/1991 |
| 5061707 | 9-deazaguanines to treat psoriasis The present invention is novel derivatives of pyrrolo[3,2-d]pyrimidines and pharmaceutical compositions and methods of use therefor. The derivatives are inhibitors of purine nucleoside phosphorylase selectively cytotoxic to T-cells but not to B-cells in t... | 10/29/1991 |
| 5061791 | 4-bromo-4'-demethylepipodophyllotoxin derivatives Preparation of 4-bromo-4'-demethylepipodophyllotoxin by reacting podophyllotoxin with hydrogen bromide at about -20° C. New antitumor compounds of the formula: ##STR1## wherein R is A--(CH2)n [A(CH2)n ] | 10/29/1991 |
| 5053521 | Various N-substituted 3-piperidine carboxylic acids or N-substituted 3-pyridinecarboxylic acids and derivatives thereof Selected analogs of nipecotic acid are the novel compounds of the present invention. The analogs are GABA uptake inhibitors for use to treat epilepsy and, thus, the invention is also pharmaceutical compositions and methods of use therefor.... | 10/01/1991 |
| 5051429 | "Pyrimidine derivatives" Novel purine derivatives, particularly novel guanines and hypoxanthines, are described as agents for treating autoimmune diseases. Also novel methods of manufacture for the derivatives, pharmaceutical compositions thereof, and methods of use therefor are ... | 09/24/1991 |
| 5036096 | Aziridino derivatives of nitroimidazoles and pharmaceutical compositions of selected derivatives The present invention is novel aziridino derivatives of nitroimidazoles and pharmaceutical compositions of selected derivatives useful as radiosensitizing or chemosensitizing agents in the treatment of hypoxic tumor cells. Also, the present invention is a... | 07/30/1991 |
| 5036089 | 2-oxazolidinone derivatives of nitroimidazoles and pharmaceutical compositions useful as sensitizing agents The present invention is novel 2-oxazolidinone analogs of nitroimidazoles; novel pharmaceutical compositions of selected analogs thereof and methods of use for the compositions as radiosensitizing or chemosensitizing agents in the treatment of hypoxic tum... | 07/30/1991 |
| 5017604 | Novel fenamic acid methyl hydroxamate derivatives having cyclooxygenase and 5-lipoxygenase inhibition The present invention is novel selected hydroxamic acid derivatives of fenamic acids having 5-lipoxygenase and cyclooxygenase inhibiting properties, pharmaceutical compositions for treating conditions advantageously affected by the inhibition and methods ... | 05/21/1991 |
| 5002950 | 7-deazaguanines as immunomodulators The present invention is various 7-deazaguanines having activity as immunomodulators. Also included are pharmaceutical compositions and methods of use thereof.... | 03/26/1991 |
| 5002703 | Benzoic acid and benzoic acid ester derivatives having antiinflammatory and analgesic activity Novel benzoic acid or benzoic acid ester derivatives, pharmaceutical compositions and methods of use thereof are the present invention. Utility is for the treatment of arthritis, asthma, Raynaud's disease, inflammatory bowel disorders, trigeminal or herpe... | 03/26/1991 |
| 4997842 | Metabolites of pirmenol The present invention relates to the + or - pirmenol stereoisomers and to selected metabolites of pirmenol or (+,-)-cis--[3-(2,6-dimethyl-1-piperidinyl))propyl]--phenyl-2 -pyridinemethanol which are active as antiarrhythmic agents. The p... | 03/05/1991 |
| 4996319 | -2-Amino-4,6-dichloro-5-(2-cyanomethyl-2-amino-5(cy anomethyl)-4,6-dichloro pyrimidine The present invention is various 7-deazaguanines having activity as immunomodulators. Also included are pharmaceutical compositions and methods of use thereof.... | 02/26/1991 |
| 4990533 | Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity Novel benzoic acid or benzoic acid ester derivatives, pharmaceutical compositions and methods of use thereof are the present invention. Utility is for the treatment of arthritis, asthma, Raynaud's disease, inflammatory bowel disorders, trigeminal or herpe... | 02/05/1991 |
| 4988702 | Novel 9-deazaguanines The present invention is novel derivatives of pyrrolo[3,2-d]pyrimidines and pharmaceutical compositions and methods of use therefor. The derivatives are inhibitors of purine nucleoside phosphorylase selectively cytotoxic to T-cells but not to B-cells in t... | 01/29/1991 |
| 4981865 | N-hydroxyamide, N-hydroxythioamide, hydroxyurea, and N-hydroxythiourea derivatives of selected nsaids as antiinflammatory agents The present invention includes N-hydroxyamide, N-hydroxyurea, N-hydroxythioamide, and N-hydroxythiourea derivatives of fenamates, indomethacin, cicloprofen, oxepinac, and indoprofen as dual inhibitors or selective inhibitors of cyclooxygenase and 5-lipoxy... | 01/01/1991 |
| 4980366 | Amide, sulfonamide, urea, carbamate, thiocarbamate, and thiourea derivatives of 4'hydroxybenzylamine having anti-inflammatory and analgesic activity Novel 4'-hydroxybenzylamine derivatives of the formula ##STR1## pharmaceutical compositions and methods of use thereof are the present invention. Utility is for the treatment of arthritis, asthma, Raynaud's disease, inflammatory bowel disorders, trig... | 12/25/1990 |
| 4980351 | 3-aminopropoxyaryl derivatives having cardiotonic and antihypertensive use and compositions thereof The present invention are novel 3-aminopropoxyaryl derivatives, compositions and methods of use thereof for treating congestive heart failure, coronary heart disease, or myocardial ischemia.... | 12/25/1990 |
| 4980095 | Sodium salt of N-C4-carboxybenzyl nonanamide Novel benzoic acid or benzoic acid ester derivatives, pharmaceutical compositions and methods of use thereof are the present invention. Utility is for the treatment of arthritis, asthma, Raynaud's disease, inflammatory bowel disorders, trigeminal or herpe... | 12/25/1990 |
| 4971959 | Trisubstituted phenyl analogs having activity for congestive heart failure Novel trisubstituted phenyl analogs are now found to have activity as for the treatment of congestive heart failure.... | 11/20/1990 |
| 4962116 | N-(2,6-disubstituted aromatic)-N'-pyridinyl ureas N-(2,6-Disubstitutedphenyl)-N'-3- and 4-pyridinyl ureas and pharmaceutically acceptable acid addition salts having anticonvulsant activity are described as well as a process for their manufacture, formulations containing the compounds and a method of trea... | 10/09/1990 |
| 4962194 | Method of preparing 51,N6-disubstituted adenosines from inosines A processing for preparing 5'-N,6-disubstituted adenosines from inosines. The adenosines have usefulness as neuroleptics, analgesics, cardiotonics, antihypertensives, antilipolytics, antihyperlipaemics, antiinflammatory agents, antithrombotic or antiembol... | 10/09/1990 |
| 4962119 | Triazole derivatives of fenamates as antiinflammatory agents The present invention is novel compounds which are 1,2,4-triazoles, derivatives of fenamates and pharmaceutically acceptable additions and base salts thereof, pharmaceutical compositions and methods of use thereof. The invention compounds are now found to... | 10/09/1990 |
