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Patent No. 5970981

Mouthguard made at least partially from an edible candy

A mouthguard includes a U-shaped upper bite plate which removably fits over upper teeth of a person, with the entire upper bite plate being made from a soft, deformable and edible gummi candy.

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Attorney: Thallemer; John D.


Number of patents: 103
Last date: September 18, 2007

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NumberTitleIssue Date
7271269Preparation of new pharmaceutically suitable salt of losartan and forms thereof with new purification and isolation methods
Pharmaceutically suitable crystalline and amorphous alkali and earth-alkali salts of 2-n-butyl-4-chloro-5-hidrox-ymethyl-1-[[2′-(1 H-tetrazole-5-yl)[1.1′-biphenyl]-4-yl]-1 Himidazole have been prepared and new manufacturing, purification and isolation procedure ...
09/18/2007
7235248Pharmaceutical compositions comprising cyclosporins
Pharmaceutical compositions comprising a cyclosporin, e.g. Ciclosporin or [Nva]2-Ciclosporin, in “microemulsion pre-concentrate” and microemulsion form. The compositions typically comprise (1.1) a C1-5alkyl or tetrahydrofurfuryl di- or part...
06/26/2007
7153970High purity amlodipine benzenesulfonate and a process for its preparation
3-ethyl 5-methyl (+/−) 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate benzenesulfonate, containing overall impurities of significantly less than 0.3% is disclosed, as well as process for its preparation, according to wh...
12/26/2006
7098362Processes for the preparation of gabapentin
The present invention relates to new processes for the preparation of gabapentin by the desilylation of a silylated gabapentin or by the silylation-desilylation of an acid addition salt of gabapentin with a silylating agent. ...
08/29/2006
H2158Process for the production of clavulanic acid salts
Use of the 2-amino-2,4,4-trimethylpentane salt of clavulanic acid as an intermediate in the production of pharmaceutically acceptable salts of clavulanic acid. ...
06/06/2006
7030151Atorvastatin calcium in a pharmaceutical form composition thereof and pharmaceutical formulation comprising atorvastatin calcium
Atorvastatin calcium, the substance known by the chemical name (R—(R*,R*))-2-(4-fluorophenyl)-β, δ-dihydroxy-5-(1-methylethyl)-3-phenyl-((phenylamino)carbonyl)-1H-pyrrole-1-heptanoic acid hemi calcium salt is known as HMG-CoA reductase inhibitor and is used as a...
04/18/2006
6962924Salt and polymorphs of desloratadine hemifumarate
This invention provides a process of preparation of novel polymorphic hemifumarate salts of 8-chloro-6,11-dihyfro-11-(4-piperidylidene)-5H-benzo[5,6]-cyclohepta[1,2-b]pyridine, hereinafter called “desloratadine”. These polymorphic salt forms show much higher sol...
11/08/2005
6949641Crystalline β-lactam intermediate
The novel intermediate compound crystalline 7-[2-(2-fomylaminothiazol-4-yl)-2 -(Z)-(methoxyimino)acetamido]-3-methoxymethyl-3-cephem-4-carboxylic acid-1 -(isopropoxy/crystallization of cefpodoxime proxetil. The crystallization process comprises dissolving or suspend...
09/27/2005
6949519Macrolide solvates
Azithromycin in the form of a monohydrate comprising from 4.0% to 6.5% of water, a process for its preparation and its use in pharmaceutical compositions. ...
09/27/2005
6936455Production of heterologous proteins using an Npro autoprotease of a pestivirus and inclusion bodies
The present invention relates to a process for the recombinant production of a desired heterologous polypeptide with a clearly defined homogenous N-terminus in a bacteria host cell. A fusion comprising a peptide with the autoproteolytic activity of an autoprotease N...
08/30/2005
6933410Process for preparing 5,6-diethyl-2,3-dihydro-1H-inden-2-amine
A process for preparing 5,6-diethyl-2,3-dihydro-1H-inden-2-amine and acid addition salts thereof from 2-aminoindan. The process comprises protecting the amino group of 2-aminoindan, acetylating the ring in the protected compound, reducing the acetyl group to ethyl t...
08/23/2005
6911472Pharmaceutical composition comprising a hmg-coa reductase inhibitor
A pharmaceutical composition comprising as an active ingredient an HMG-CoA reductase inhibitor and an aminosugar. ...
06/28/2005
6897307Process for preparing 2,6-diaminopurine derivatives
A one-pot process for preparing 2,6-diaminopurine derivatives or an acid addition salt thereof comprising: (i) reacting a purine compound with an amine compound in the presence of a tertiary amine at a pH of 7 to 14 to form a 6-substituted aminopurine derivative, an...
05/24/2005
6878749Method of treating metabolic disorders, especially diabetes, or a disease or condition associated with diabetes
The invention relates to a combination, such as a combined preparation or pharmaceutical composition, respectively, which comprises nateglinide (1) stet or repaglinide and at least one other antidiabetic compound selec...
04/12/2005
6869963Stable pharmaceutical compositions containing an ACE inhibitor
A stable pharmaceutical composition comprising about 1 wt. % to about 80 wt. % of an ACE inhibitor or a pharmaceutical acceptable salt thereof, about 1 wt. % to about 70 wt. % of an alkali or alkaline earth metal carbonate, and about 1 wt. % to about 80 wt. % of hyd...
03/22/2005
6835838Process for the manufacture of organic compounds
A method for preparing an alkali metal salt comprising: (a) condensing a disilyloxydiene with an aldehyde in the presence of a titanium (IV) catalyst in an inert solvent to form a 5(S)-hydroxy-3-ketoester; (b) reducing the 5(S)-hydroxy-3-ketoester to a 3(R),5(S)-dih...
12/28/2004
6835829Purification process
Processes for the depletion of 7-ADCA in mixtures of vinyl-ACA with 7-ADCA via novel salts of vinyl-ACA or via chromatography. ...
12/28/2004
6825345Process for purification of a cephalosporin derivative
A process for the purification of cefixime via a novel tert-octylamine salt of a cefixime intermediate of formula V which may be crystalline and which may be produced in a one-pot reaction from 7-amino-3-vinyl-ceph-3-e...
11/30/2004
6787649Cephalosporin intermediates
A process which comprises (i) acylating a compound of formula II with a compound of formula IV to obtain a compound of formula I ...
09/07/2004
6784193Mutilin derivatives and their use as antibacterials
A compound of formula (I) wherein R2 is arylene or heterocyclene; or R and R2 together with the nitrogen atom to which they are attached form non-aromatic heterocyclene; and the other residues have various meanings, useful as pharmaceuticals, e...
08/31/2004
6777549β-lactam production
A process for the production of a compound of formula comprising i) silylating a compound of formula then reacting a resulting with a compound of formula
08/17/2004
6767555Pharmaceutical compositions
This invention provides composition comprising a cyclosporin and a carrier medium. ...
07/27/2004
6753445Pleuromutilin derivatives having antibacterial activity
A compound selected from 14—O—[(cycloalkyl-sulfanyl)acetyl]mutilins; 14—O—[(cycloalkyl-alkyl-sulfanyl)acetyl] mutilins; 14—O—[(cycloalkoxy)acetyl] mutilins; and 14—O—[(cycloalkyl-alkoxy)acetyl] mutilins and its use as a pharmaceutical. ...
06/22/2004
6740776Air oxidation of an aromatic aldehyde to an aromatic acid
A low temperature process for preparing an aromatic acid having formula (I), said process comprising reacting an aromatic aldehyde having formula (II) with a gas having an ox...
05/25/2004
6723339Oil-free pharmaceutical compositions containing cyclosporin A
The present invention provides a hard gelatine capsule containing a pharmaceutical composition comprising cyclosporin A in a mixture with a surfactant of HLB value at least 10, substantially free of any oil and when a hydrophilic phase is present, the hydrophilic ph...
04/20/2004
6670477Synthesis of enantiomerically enriched 4-piperidinylglycine
A process for making enantiomerically enriched 4-piperidinylglycine having the formula (I), ##STR1## said process comprising (a) combining N-protected glycine ester with 4-piperidone to form didehydroamino acid ester; (b) reducing the didehydroamino ...
12/30/2003
6653503Microwave irradiation process for preparing methyl esters
An accelerated process for preparing a methyl ester having formula (III) ##STR1## said process comprising reacting a carboxylic acid or salt thereof having formula (I) ##STR2## with dimethyl carbonate having formula (II) ##STR3## in the presence of a...
11/25/2003
6649168Pharmaceutical compositions comprising TGF-beta
This invention provides pharmaceutical compositions comprising TGF-ଲ....
11/18/2003
6605613Macrolides
A mixture comprising a poly-ene macrolide and an antioxidant. Preferably, the poly-ene macrolide is rapamycin and the antioxidant is 2,6-di-tert.-butyl-4-methylphenol. The presence of the antioxidant improves the stability of the poly-ene macrolide to oxi...
08/12/2003
6599535Pharmaceutical compositions
A pharmaceutical composition in the form of a solid dispersion comprising a macrolide, e.g. a rapamycin or an ascomycin, and a carrier medium....
07/29/2003
6596877Accelerated process for preparing O-methyl phenols, N-methyl heteroaromatic compounds, and methylated aminophenols
An accelerated process for preparing an O-methyl phenol comprising reacting a phenol with dimethyl carbonate in the presence of a catalyst selected from 1,8-diazabicyclo[5.4.0]undec-7-ene; 1,4-diazabicyclo[2.2.2]octane; and dimethylaminopyridine. Accordin...
07/22/2003
6596260Aerosol container and a method for storage and administration of a predetermined amount of a pharmaceutically active aerosol
The invention relates to an aerosol container for pharmaceutically active aerosols that are to be administered in predetermined amounts and that are supplied in the container in the form of a suspension, the suspension also comprising, in addition to a ph...
07/22/2003
6589536Soft gelatin capsule manufacture
Soft gelatin capsules having a capsule shell comprising gelatin, plasticizers and, if desired or required, further auxiliary agents, and a capsule filling containing a solvent including a migrateable solvent such as 1,2-propyleneglycol as a solvent in the...
07/08/2003
6559188Method of treating metabolic disorders especially diabetes, or a disease or condition associated with diabetes
The invention relates to a combination, such as a combined preparation or pharmaceutical composition, respectively, which comprises nateglinide (I) ##STR1## or repaglinide and at least one other antidiabetic compound selected from the group consisting of ...
05/06/2003
6555132Soft gelatin capsule manufacture
Soft gelatin capsules having a capsule shell comprising gelatin, plasticizers and, if desired or required, further auxiliary agents, and a capsule filling containing a solvent including a migrateable solvent such as 1,2-propyleneglycol as a solvent in the...
04/29/2003
6515167Low temperature process for preparing methyl esters
A low temperature process for preparing a methyl ester having formula (III) ##STR1## said process comprising reacting a carboxylic acid or salt thereof having formula (I) ##STR2## with dimethyl carbonate having formula (II) ##STR3## in the presence o...
02/04/2003
6503883Pharmaceutical preparations for the targeted treatment of crohn's disease and ulcerative colitis
The invention relates to a pharmaceutical preparation, which contains an immunosuppressive active agent in dissolved form in a starch capsule, or hard or soft gelatin capsule which has been coated with one or several polymer films. The invention further r...
01/07/2003
6475519Oil-free pharmaceutical compositions containing cyclosporin A
The present invention provides a hard gelatine capsule containing a pharmaceutical composition comprising cyclosporin A in a mixture with a surfactant of HLB value of at least 10, substantially free of any oil and when a hydrophilic phase is present, the ...
11/05/2002
6468968Cyclosporin galenic forms
Pharmaceutical compositions comprising a cyclosporin as active ingredient, a fatty acid triglyceride, a glycerol fatty acid partial ester or propylene glycol or sorbitol complete or partial ester, preferably, and a tenside having an HLB of at least 10....
10/22/2002
6458770Parenteral formulations comprising carbamazepine or its derivatives
The invention is concerned with a parenteral formulation comprising a 5H-dibenz(b,f)azepine-5-carboxamide and an aqueous-based solvent. The parenteral formulation is useful in the treatment of seizures resulting from, e.g. epileptic attack....
10/01/2002
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