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| Number | Title | Issue Date |
| 8173801 | Processes for the production of polymorphic forms of rifaximin Crystalline polymorphous forms of rifaximin (INN) antibiotic named rifaximin α and rifaximin β, and a poorly crystalline form named rifaximin γ, useful in the production of medicinal preparations containing rifaximin for oral and topical use and obtained by means... | 05/08/2012 |
| 8168635 | Modulators of central nervous system neurotransmitters Disclosed are agents having pharmacological activity against cellular receptors and intracellular signaling, particularly receptors and signaling pathways of central nervous system (CNS) neurotransmitters. Also disclosed are related methods and compositions for the ... | 05/01/2012 |
| 8158781 | Polymorphic forms α, β and γ of rifaximin Crystalline polymorphous forms of rifaximin (INN) antibiotic named rifaximin α and rifaximin β, and a poorly crystalline form named rifaximin γ, useful in the production of medicinal preparations containing rifaximin for oral and topical use and obtained by means... | 04/17/2012 |
| 8158644 | Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin Crystalline polymorphous forms of rifaximin (INN), referred to as rifaximin α and rifaximin β, and a poorly crystalline form referred to as rifaximin γ, useful in the production of medicaments containing rifaximin for oral and topical use and obtained by means of... | 04/17/2012 |
| 8141521 | Food dispensing interlocking animal toy system An animal toy features the ability to connect two or more separate toys of varying shape, size, color, and/or texture, together to create larger and more complex toy systems. The animal toy allows an almost endless variety of toy systems to capture the interest as w... | 03/27/2012 |
| 8133208 | Injection control method and device An injection control device having a metered/controlled injection rate proportional to the rate of withdrawal/injection, suitable for cosmetic as well as other applications is described. For example, after the cannula is advanced into an object, the cannula is withd... | 03/13/2012 |
| 8129518 | Synthetic polysaccharide antigens for immunological intervention in disease Provided are synthetic polysaccharide antigens (SPAs) with anti-inflammatory or inflammatory immunomodulatory properties, depending on their structure. Also provided are compositions comprising these SPAs, and methods of using these SPAs and compositions to either p... | 03/06/2012 |
| D655357 | Abdominal exercise device | 03/06/2012 |
| 8119618 | Compositions and methods for the treatment of inflammatory diseases Inflammatory bowel diseases are represented by two idiopathic disorders, which include ulcerative colitis and Crohn's disease. Ulcerative colitis is restricted to the colon and involves uncertain and inflammation of the lining (mucosa) of the large intestine. Crohn'... | 02/21/2012 |
| 8118718 | Abdominal exercise training device An abdominal training device includes a stationary base with a user support surface and a hub connected to a track with a friction mitigation unit and a track anchor. A console is slidably mounted on the track and includes a hand support member and a console anchor.... | 02/21/2012 |
| 8110673 | Aggregation sensor and solutions and kits comprising the same This invention relates to an aggregation sensor useful for the detection and analysis of aggregants in a sample, and methods, articles and compositions relating to such a sensor. The sensor comprises first and second optically active units, where energy may be trans... | 02/07/2012 |
| 8109390 | Wafer container with overlapping wall structure Improvements in a semiconductor wafer container including improvements in side protection to the wafers, improved cover design to minimize rotation, a simplified top cover orientation mechanism and an improved bottom holding mechanism for automation. The side protec... | 02/07/2012 |
| 8105308 | Permanent umbilical hollow tube An apparatus is provided. The apparatus includes a tube having a first end and a second end. The second end prevents access to an inner wall of the tube. Further, the apparatus includes a valve operably connected to the first end of the tube and configured to provid... | 01/31/2012 |
| 8105221 | Abdominal exercise device An exercise device for the mid to lower body muscles comprising an inclined base, a base frame to support the base a first support bar and a second support bar, the first and the second support bar each having a mounting end and a support end, wherein the first supp... | 01/31/2012 |
| 8101651 | Compounds with activity at estrogen receptors Disclosed herein are compounds of Formula I as disclosed herein, methods of modulating the activity of an estrogen receptor and methods of treating a disorder associated with estrogen receptors. ... | 01/24/2012 |
| 8101416 | Compositions for detection and analysis of polynucleotides using light harvesting multichromophores Methods, compositions and articles of manufacture for assaying a sample for a target polynucleotide are provided. A sample suspected of containing the target polynucleotide is contacted with a polycationic multichromophore and a sensor PNA complementary to the targe... | 01/24/2012 |
| D652461 | Modified abdominal exercise device | 01/17/2012 |
| 8071378 | ZNF206: regulator of embryonic stem cell self-renewal and pluripotency We have identified ZNF206, a novel repressor of human embryonic stem cell (hESC) differentiation. Repressing extra-embryonic endoderm development preserves the pluripotent state of human embryonic stem cells, and, conversely downregulating expression of ZNF206 in hE... | 12/06/2011 |
| 8057609 | Portable fuel cell device A fuel cell device comprising: (a) a catalytic oxidizer; (b) means for delivering gaseous fuel and oxidizer to the catalytic oxidizer; and (c) a fuel cell assembly located in the vicinity of the catalytic oxidizer such that the fuel cell assembly is able to be heate... | 11/15/2011 |
| 8022246 | Neuroprotective compositions and methods Neurite outgrowth-promoting prostaglandins (NEPPs) and other electrophilic compounds bind to Keap1, a negative regulator of the transcription factor Nrf2, and prevent Keap1-mediated inactivation of Nrf2 and, thus, enhance Nrf2 translocation into the nucleus of neuro... | 09/20/2011 |
| D642342 | Food dispensing animal toy | 07/26/2011 |
| 7982002 | Nucleic acid encoding proteins involved in protein degradation, products and methods related thereto In accordance with the present invention, there are provided novel Siah-Mediated-Degradation-Proteins (SMDPS) and/or SCF-Complex Proteins (SCPs). Nucleic acid sequences encoding such proteins and assays employing same are also disclosed. The invention SMDPs and/or S... | 07/19/2011 |
| 7968714 | Optical determination of glucose utilizing boronic acid adducts The present invention concerns an improved optical method and optical sensing device for determining the levels of polyhydroxyl-substituted organic molecules in vitro and/or in vivo in aqueous media. The range of detection is between about 400 and 800 nm. In particu... | 06/28/2011 |
| 7964402 | Methods for culture and production of single cell populations of human embryonic stem cells We used Accutase™, a commercially available cell detachment solution, for single cell propagation of pluripotent hESCs. Unlike trypsin dissociation, Accutase treatment does not significantly affect the plating efficiency of hESC dissociation into single cells. Cul... | 06/21/2011 |
| 7927267 | Abdominal exercise device An exercise device is disclosed having at least a base, first and second knee supports which are bilaterally coupled to first and second pivots located off from the center of the base. Independently rotatable knee pads are coupled to the perimeter-side end of the fi... | 04/19/2011 |
| 7923553 | Processes for the production of polymorphic forms of rifaximin Crystalline polymorphous forms of rifaximin (INN) antibiotic named rifaximin α and rifaximin β, and a poorly crystalline form named rifaximin γ, useful in the production of medicinal preparations containing rifaximin for oral and topical use and obtained by means... | 04/12/2011 |
| 7922906 | Septic system cleaning method A composition including the fermentation supernatant from a fermentation of yeast is intended to be conveniently introduced through the wastewater plumbing system of a private home or other facility into a septic system servicing the home or other facility to substa... | 04/12/2011 |
| 7915275 | Use of polymorphic forms of rifaximin for medical preparations The present invention relates to Rifaximin polymorphic forms α, β and γ, to their use in medicinal preparations for the oral or topical route and to therapeutic methods using them. ... | 03/29/2011 |
| 7914984 | Conformationally flexible cationic conjugated polymers Methods, compositions and articles of manufacture involving cationic conjugated conformationally flexible polymers are provided. A method for the synthesis of cationic water-soluble polymers with linkages along the polymer main chain structure which disrupt the abil... | 03/29/2011 |
| 7910305 | Methods for screening for compounds that modulate insulin promoter activity Compositions and methods are provided for screening for compounds that modulate insulin promoter activity. Vectors that express green fluorescent protein under the control of the human insulin promoter are introduced into mouse and human cells in which the insulin p... | 03/22/2011 |
| 7906542 | Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin Crystalline polymorphous forms of rifaximin (INN), referred to as rifaximin α and rifaximin β, and a poorly crystalline form referred to as rifaximin γ, useful in the production of medicaments containing rifaximin for oral and topical use and obtained by means of... | 03/15/2011 |
| 7906132 | Anti-infectious, biocompatible titanium coating for implants, and method for the production thereof The present invention relates to a method for the preparation of a biocompatible metal ion-containing titanium oxide coating on an implant wherein the metal ions can be eluted under physiological conditions and are homogeneously dispersed within the coating, as well... | 03/15/2011 |
| 7902206 | Polymorphic forms α, β and γ of rifaximin Crystalline polymorphous forms of rifaximin (INN) antibiotic named rifaximin α and rifaximin β, and a poorly crystalline form named rifaximin γ, useful in the production of medicinal preparations containing rifaximin for oral and topical use and obtained by means... | 03/08/2011 |
| 7897684 | Conjugated polymers suitable for strand-specific polynucleotide detection in homogeneous and solid state assays The invention further relates to polycationic multichromophores, which may be conjugated polymers, and methods, articles and compositions employing them as described herein. In some aspects, the invention relates to methods, articles and compositions for the detecti... | 03/01/2011 |
| 7887782 | Radiotherapeutic formulations containing 224RA and a method for their production The invention relates to novel radiotherapeutic formulations containing 224Ra and methods for their production. The invention discloses, in particular, radiotherapeutic formulations comprising at least one salt of the isotope 224Ra, which are c... | 02/15/2011 |
| D631108 | Modified abdominal exercise device | 01/18/2011 |
| 7866082 | Incapacitating high intensity incoherent light beam A long range, high intensity spotlight for human incapacitation and control that uses an incoherent collimated constant light source of sufficient intensity and focus to cause temporary incapacitation of a person for a period of time when illuminated by the beam wit... | 01/11/2011 |
| 7811755 | Methods and articles for strand-specific polynucleotide detection with cationic multichromophores The invention relates to methods, articles and compositions for the detection and analysis of biomolecules in a sample. Provided assays include those determining the presence of a target biomolecule in a sample or its relative amount, or the assays may be quantitati... | 10/12/2010 |
| D624711 | Dog toy | 09/28/2010 |
| 7780165 | Gaming system The present invention provides a gaming apparatus adapted for substantially continuous play, comprising a first set of elements divisible into two or more distinguishable subsets; a second set of destinations divisible into two or more distinguishable subsets; selec... | 08/24/2010 |