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| Number | Title | Issue Date |
| 7060275 | Use of protein biomolecular targets in the treatment and visualization of brain tumors The present invention relates to the use of proteins which are differentially expressed in primary brain tumor tissues, as compared to normal brain tissues, as biomolecular targets for brain tumor treatment therapies. Specifically, the present invention relates to t... | 06/13/2006 |
| 7014838 | Use of biomolecular targets in the treatment and visualization of brain tumors The present invention relates to the use of proteins that are differentially expressed in primary brain tumor tissues, as compared to normal brain tissues, as biomolecular targets for brain tumor treatment therapies. Specifically, the present invention relates to th... | 03/21/2006 |
| 6977142 | High-throughput turbidometric assay for screening inhibitors of protein disulfide isomerase activity Methods for performing an end-point assay of protein disulfide isomerase activity. The method may be based on the enzyme-catalyzed reduction of insulin in the presence of dithiothreitol; measuring the aggregation of reduced insulin chains at 650 nm; and using hydrog... | 12/20/2005 |
| 6924109 | High-throughput transcriptome and functional validation analysis Methods for correlating genes and gene function are provided. Such methods generally involve selecting a candidate gene that appears to be correlated with a particular cellular state or activity and then validating the role of the candidate gene in establishment of ... | 08/02/2005 |
| 6876930 | Automated pathway recognition system There is a pressing need for computer-implemented tools that can summarize and present the enormous amounts of public literature to facilitate analysis of gene expression data. The present invention provides techniques and systems for efficiently integrating public ... | 04/05/2005 |
| 6846641 | In vitro ischemia model A tissue culture model of oxygen/glucose deprivation induced cell death is provided, which is useful in the analysis of the mechanisms of cell death following brain ischemia, and for screening anti-ischemic drugs. By adopting the in vivo concentrations of calcium, p... | 01/25/2005 |
| 6841351 | High-throughput transcriptome and functional validation analysis Methods for correlating genes and gene function are provided. Such methods generally involve selecting a candidate gene that appears to be correlated with a particular cellular state or activity and then validating the role of the candidate gene in establishment of ... | 01/11/2005 |
| 6670138 | Method of diagnosing ischemic stroke via UCP-2 detection The present invention identifies a gene whose gene product provides a protective effect against neurological disorders or neuronal injuries. Further, the invention provides methods for diagnosing or assessing an individual's susceptibility to a neuronal i... | 12/30/2003 |
