...During the Civil War, the Confederacy established its own Patent Office which issued 266 patents, a third of which concerned implements of war.
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| Number | Title | Issue Date |
| 8173801 | Processes for the production of polymorphic forms of rifaximin Crystalline polymorphous forms of rifaximin (INN) antibiotic named rifaximin α and rifaximin β, and a poorly crystalline form named rifaximin γ, useful in the production of medicinal preparations containing rifaximin for oral and topical use and obtained by means... | 05/08/2012 |
| 8168635 | Modulators of central nervous system neurotransmitters Disclosed are agents having pharmacological activity against cellular receptors and intracellular signaling, particularly receptors and signaling pathways of central nervous system (CNS) neurotransmitters. Also disclosed are related methods and compositions for the ... | 05/01/2012 |
| 8158781 | Polymorphic forms α, β and γ of rifaximin Crystalline polymorphous forms of rifaximin (INN) antibiotic named rifaximin α and rifaximin β, and a poorly crystalline form named rifaximin γ, useful in the production of medicinal preparations containing rifaximin for oral and topical use and obtained by means... | 04/17/2012 |
| 8158644 | Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin Crystalline polymorphous forms of rifaximin (INN), referred to as rifaximin α and rifaximin β, and a poorly crystalline form referred to as rifaximin γ, useful in the production of medicaments containing rifaximin for oral and topical use and obtained by means of... | 04/17/2012 |
| 8141521 | Food dispensing interlocking animal toy system An animal toy features the ability to connect two or more separate toys of varying shape, size, color, and/or texture, together to create larger and more complex toy systems. The animal toy allows an almost endless variety of toy systems to capture the interest as w... | 03/27/2012 |
| 8129518 | Synthetic polysaccharide antigens for immunological intervention in disease Provided are synthetic polysaccharide antigens (SPAs) with anti-inflammatory or inflammatory immunomodulatory properties, depending on their structure. Also provided are compositions comprising these SPAs, and methods of using these SPAs and compositions to either p... | 03/06/2012 |
| 8119618 | Compositions and methods for the treatment of inflammatory diseases Inflammatory bowel diseases are represented by two idiopathic disorders, which include ulcerative colitis and Crohn's disease. Ulcerative colitis is restricted to the colon and involves uncertain and inflammation of the lining (mucosa) of the large intestine. Crohn'... | 02/21/2012 |
| 8110673 | Aggregation sensor and solutions and kits comprising the same This invention relates to an aggregation sensor useful for the detection and analysis of aggregants in a sample, and methods, articles and compositions relating to such a sensor. The sensor comprises first and second optically active units, where energy may be trans... | 02/07/2012 |
| 8109390 | Wafer container with overlapping wall structure Improvements in a semiconductor wafer container including improvements in side protection to the wafers, improved cover design to minimize rotation, a simplified top cover orientation mechanism and an improved bottom holding mechanism for automation. The side protec... | 02/07/2012 |
| 8105308 | Permanent umbilical hollow tube An apparatus is provided. The apparatus includes a tube having a first end and a second end. The second end prevents access to an inner wall of the tube. Further, the apparatus includes a valve operably connected to the first end of the tube and configured to provid... | 01/31/2012 |
| 8101651 | Compounds with activity at estrogen receptors Disclosed herein are compounds of Formula I as disclosed herein, methods of modulating the activity of an estrogen receptor and methods of treating a disorder associated with estrogen receptors. ... | 01/24/2012 |
| 8101416 | Compositions for detection and analysis of polynucleotides using light harvesting multichromophores Methods, compositions and articles of manufacture for assaying a sample for a target polynucleotide are provided. A sample suspected of containing the target polynucleotide is contacted with a polycationic multichromophore and a sensor PNA complementary to the targe... | 01/24/2012 |
| 8071378 | ZNF206: regulator of embryonic stem cell self-renewal and pluripotency We have identified ZNF206, a novel repressor of human embryonic stem cell (hESC) differentiation. Repressing extra-embryonic endoderm development preserves the pluripotent state of human embryonic stem cells, and, conversely downregulating expression of ZNF206 in hE... | 12/06/2011 |
| 8057609 | Portable fuel cell device A fuel cell device comprising: (a) a catalytic oxidizer; (b) means for delivering gaseous fuel and oxidizer to the catalytic oxidizer; and (c) a fuel cell assembly located in the vicinity of the catalytic oxidizer such that the fuel cell assembly is able to be heate... | 11/15/2011 |
| 8022246 | Neuroprotective compositions and methods Neurite outgrowth-promoting prostaglandins (NEPPs) and other electrophilic compounds bind to Keap1, a negative regulator of the transcription factor Nrf2, and prevent Keap1-mediated inactivation of Nrf2 and, thus, enhance Nrf2 translocation into the nucleus of neuro... | 09/20/2011 |
| D642342 | Food dispensing animal toy | 07/26/2011 |
| 7982002 | Nucleic acid encoding proteins involved in protein degradation, products and methods related thereto In accordance with the present invention, there are provided novel Siah-Mediated-Degradation-Proteins (SMDPS) and/or SCF-Complex Proteins (SCPs). Nucleic acid sequences encoding such proteins and assays employing same are also disclosed. The invention SMDPs and/or S... | 07/19/2011 |
| 7968714 | Optical determination of glucose utilizing boronic acid adducts The present invention concerns an improved optical method and optical sensing device for determining the levels of polyhydroxyl-substituted organic molecules in vitro and/or in vivo in aqueous media. The range of detection is between about 400 and 800 nm. In particu... | 06/28/2011 |
| 7964402 | Methods for culture and production of single cell populations of human embryonic stem cells We used Accutase™, a commercially available cell detachment solution, for single cell propagation of pluripotent hESCs. Unlike trypsin dissociation, Accutase treatment does not significantly affect the plating efficiency of hESC dissociation into single cells. Cul... | 06/21/2011 |
| 7923553 | Processes for the production of polymorphic forms of rifaximin Crystalline polymorphous forms of rifaximin (INN) antibiotic named rifaximin α and rifaximin β, and a poorly crystalline form named rifaximin γ, useful in the production of medicinal preparations containing rifaximin for oral and topical use and obtained by means... | 04/12/2011 |
| 7922906 | Septic system cleaning method A composition including the fermentation supernatant from a fermentation of yeast is intended to be conveniently introduced through the wastewater plumbing system of a private home or other facility into a septic system servicing the home or other facility to substa... | 04/12/2011 |
| 7915275 | Use of polymorphic forms of rifaximin for medical preparations The present invention relates to Rifaximin polymorphic forms α, β and γ, to their use in medicinal preparations for the oral or topical route and to therapeutic methods using them. ... | 03/29/2011 |
| 7910305 | Methods for screening for compounds that modulate insulin promoter activity Compositions and methods are provided for screening for compounds that modulate insulin promoter activity. Vectors that express green fluorescent protein under the control of the human insulin promoter are introduced into mouse and human cells in which the insulin p... | 03/22/2011 |
| 7906542 | Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin Crystalline polymorphous forms of rifaximin (INN), referred to as rifaximin α and rifaximin β, and a poorly crystalline form referred to as rifaximin γ, useful in the production of medicaments containing rifaximin for oral and topical use and obtained by means of... | 03/15/2011 |
| 7902206 | Polymorphic forms α, β and γ of rifaximin Crystalline polymorphous forms of rifaximin (INN) antibiotic named rifaximin α and rifaximin β, and a poorly crystalline form named rifaximin γ, useful in the production of medicinal preparations containing rifaximin for oral and topical use and obtained by means... | 03/08/2011 |
| 7887782 | Radiotherapeutic formulations containing 224RA and a method for their production The invention relates to novel radiotherapeutic formulations containing 224Ra and methods for their production. The invention discloses, in particular, radiotherapeutic formulations comprising at least one salt of the isotope 224Ra, which are c... | 02/15/2011 |
| 7866082 | Incapacitating high intensity incoherent light beam A long range, high intensity spotlight for human incapacitation and control that uses an incoherent collimated constant light source of sufficient intensity and focus to cause temporary incapacitation of a person for a period of time when illuminated by the beam wit... | 01/11/2011 |
| D624711 | Dog toy | 09/28/2010 |
| 7781472 | Therapy for the treatment of disease Disclosed herein are pharmaceutical compositions comprising oxybutynin, or a free base thereof or a pharmaceutically acceptable salt thereof, and pilocarpine, or a free base thereof or a pharmaceutically acceptable salt thereof. Also disclosed are methods of treatin... | 08/24/2010 |
| 7776914 | Esterified fatty acid composition The invention is directed to compositions comprising lecithin, olive oil, esterified fatty acids and mixed tocophenols for use in the treatment and prevention of various types of arthritis and other inflammatory joint conditions, periodontal diseases and psoriasis, ... | 08/17/2010 |
| 7759301 | Increasing surface active properties of surfactants Surfactant-containing compositions are described which include a protein component that has the effect of improving the surface-active properties of the surfactants contained in the compositions. The surfactant-containing compositions having the protein component de... | 07/20/2010 |
| 7691832 | Methods of treatment of inflammatory diseases Inflammatory bowel diseases are represented by two idiopathic disorders, which include ulcerative colitis and Crohn's disease. Ulcerative colitis is restricted to the colon and involves uncertain and inflammation of the lining (mucosa) of the large intestine. Crohn'... | 04/06/2010 |
| 7678821 | Compositions for the treatment of overactive bladder Disclosed herein are pharmaceutical compositions comprising combinations of tolterodine, an antimuscarinic agent, and pilocarpine, a compound that causes stimulation of salivary glands. Also disclosed are methods of treating a patient suffering from overactive bladd... | 03/16/2010 |
| 7666894 | Therapy for the treatment of disease Disclosed herein are pharmaceutical compositions comprising oxybutynin, or a free base thereof or a pharmaceutically acceptable salt thereof, and pilocarpine, or a free base thereof or a pharmaceutically acceptable salt thereof. Also disclosed are methods of treatin... | 02/23/2010 |
| 7659237 | Increasing surface-active properties of surfactants Surfactant-containing compositions are described which include a protein component that has the effect of improving the surface-active properties of the surfactants contained in the compositions. The surfactant-containing compositions having the protein component de... | 02/09/2010 |
| 7658848 | Septic system cleaning A composition including the fermentation supernatant from a fermentation of yeast is intended to be conveniently introduced through the wastewater plumbing system of a private home or other facility into a septic system servicing the home or other facility to substa... | 02/09/2010 |
| 7645730 | Surfactant composition with a reduction of surface tension, interfacial tension, and critical micelle concentration using a protein-based surfactant synergist Surfactant-containing compositions are described which include a protein component that has the effect of improving the surface-active properties of the surfactants contained in the compositions. The surfactant-containing compositions having the protein component de... | 01/12/2010 |
| 7638507 | Compositions for treatment of inflammatory diseases Inflammatory bowel diseases are represented by two idiopathic disorders, which include ulcerative colitis and Crohn's disease. Ulcerative colitis is restricted to the colon and involves uncertain and inflammation of the lining (mucosa) of the large intestine. Crohn'... | 12/29/2009 |
| 7612199 | Polymorphic forms α, β, and γ of rifaximin Crystalline polymorphous forms of rifaximin (INN) antibiotic named rifaximin α and rifaximin β, and a poorly crystalline form named rifaximin γ, useful in the production of medicinal preparations containing rifaximin for oral and topical use and obtained by means... | 11/03/2009 |
| 7612111 | Esterified fatty acid composition The invention is directed to compositions comprising lecithin, olive oil, esterified fatty acids and mixed tocophenols for use in the treatment and prevention of various types of arthritis and other inflammatory joint conditions, periodontal diseases and psoriasis, ... | 11/03/2009 |