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Pet Toilet-Like Water Disk and Food Storage
One pet-friendly inventor patented "a device for watering pets, e.g., a dog or cat." The device, he helpfully noted, "has the general shape of a toilet."
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| Number | Title | Issue Date |
| 8071097 | Apoptotic anti-IgE antibodies The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders. ... | 12/06/2011 |
| 8012754 | Antibody compositions A process for purifying an antibody is provided. In this process, a mixture containing the antibody and a contaminant is subjected to low pH hydrophobic interaction chromatography (LPHIC) at low salt concentration. The antibody is eluted from the column in the fract... | 09/06/2011 |
| 7951916 | Il-1 related polypeptides The present invention is directed to novel polypeptides having homology to the IL-1-like family of proteins and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric p... | 05/31/2011 |
| 7786272 | Antibodies to PRO352 The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of ... | 08/31/2010 |
| 7749695 | PRO polypeptides for diagnosis of systemic lupus erythematosis The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases. ... | 07/06/2010 |
| 7662926 | Anti-Fc-gamma receptor antibodies, bispecific variants and uses therefor The present application describes antibodies that selectively bind human FcγRIIB, with little or no binding to other human FcγRs, e.g., human FcγRIIA. The invention also provides isolated bispecific antibodies comprising an antibody that selectively binds FcγRII... | 02/16/2010 |
| 7655229 | Anti-FC-gamma RIIB receptor antibody and uses therefor The present application describes antibodies that selectively bind human FcγRIIB, with little or no binding to other human FcγRs, e.g., human FcγRIIA. The invention also provides isolated bispecific antibodies comprising an antibody that selectively binds FcγRII... | 02/02/2010 |
| 7632658 | Method of using aminopeptidase to produce cleaved polypeptides A gram-negative bacterial cell is described that is deficient in a chromosomal gene present in a wild-type such cell which gene shares at least 80% sequence identity with the native sequence of the yfcK gene and encodes an aminopeptidase. Alternatively, a gram-negat... | 12/15/2009 |
| 7579448 | Purification of microbial cell fermentation homogenates A method for purifying a desired heterologous polypeptide from microbial fermentation broth or homogenate in which it is produced and solubilized is described. This method involves adding to the broth or homogenate an effective amount of a solution of 6,9-diamino-2-... | 08/25/2009 |
| 7351816 | Nucleic acid encoding anti-IgE antibodies The present invention describes IgE antagonists (including variant anti-IgE antibodies) and their use in diagnosis, therapy or prophylaxis of allergic and other IgE-mediated disorders, including asthma, food allergies, hypersensitivity and anaphylactic reactions. | 04/01/2008 |
| 7303896 | Nucleic acid encoding novel type-1 cytokine receptor GLM-R The present invention is directed to novel polypeptides and variants thereof of GLM-R polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptid... | 12/04/2007 |
| 7268112 | Use of insulin for the treatment of cartilaginous disorders The present invention relates to methods for the treatment and repair of cartilage, including cartilage damaged by injury or cartilaginous disorders, including arthritis, comprising the administration of insulin and/or insulin variants. Optionally, the administratio... | 09/11/2007 |
| 7259245 | Anti-fused antibodies The present invention relates to nucleotide sequences, including expressed sequence tags (ESTs), oligonucleotide probes, polypeptides, vectors and host cells expressing, immunoadhesins, agonists and antagonists (including antibodies) to human & vertebrate fused.... | 08/21/2007 |
| 7157085 | Method for treating IgE-mediated disorders The present invention relates to a method for adjusting the affinity of a polypeptide to a target molecule by a combination of steps, including: (1) the identification of aspartyl residues which are prone to isomerization; (2) the substitution of alternative residue... | 01/02/2007 |
| 7101851 | IgE receptor antagonists The invention provides novel compounds which bind to the high affinity receptor for immunoglobulin E (IgE) designated FcεRI and methods for identifying and preparing such compounds. In particular aspects, the invention provides to the treatment of disorders mediate... | 09/05/2006 |
| 7049411 | Human anti-factor IX/IXa antibodies The invention provides for the isolation, identification, synthesis, expression and purification of antibodies reactive with factor IX (FIX)/factor IXa (IXa). In particular aspects, the invention provides human antibodies reactive with the human FIX Gla domain. The ... | 05/23/2006 |
| 7005504 | Antibody fragment-peg conjugates Humanized anti-IL-8 monoclonal antibodies and variants thereof are described for use in diagnostic applications and in the treatment of inflammatory disorders. Also described is a conjugate formed by an antibody fragment covalently attached to a non-proteinaceous po... | 02/28/2006 |
| 6914129 | Anti-IgE antibodies The present invention describes IgE antagonists (including variant anti-IgE antibodies) and their use in diagnosis, therapy or prophylaxis of allergic and other IgE-mediated disorders, including asthma, food allergies, hypersensitivity and anaphylactic reactions. | 07/05/2005 |
| 6875432 | Reduced-viscosity concentrated protein formulations The present application concerns concentrated protein formulations with reduced viscosity, which are particularly suitable for subcutaneous administration. The application further concerns a method for reducing the viscosity of concentrated protein formulations.... | 04/05/2005 |
| 6761889 | Anti-IgE antibodies The present invention relates to a method for adjusting the affinity of a polypeptide to a target molecule by a combination of steps, including: (1) the identification of aspartyl residues which are prone to isomerization; (2) the substitution of alternative residue... | 07/13/2004 |
| 6723833 | Therapeutic compositions comprising anti-IGE antibodies and immunosuppressive agent The present invention relates to a method for adjusting the affinity of a polypeptide to a target molecule by a combination of steps, including: (1) the identification of aspartyl residues which are prone to isomerization; (2) the substitution of alternative residue... | 04/20/2004 |
| 6709838 | Nucleic acid encoding patched-2 The present invention relates to nucleotide sequences, including expressed sequence tags (ESTs), oligonucleotide probes, polypeptides, antibodies, vectors and host cells expressing, immunoadhesins, agonists and antagonists to patched-2. ... | 03/23/2004 |
| 6699472 | Method of treating allergic disorders The present invention describes IgE antagonists (including variant anti-IgE antibodies) and their use in diagnosis, therapy or prophylaxis of allergic and other IgE-mediated disorders, including asthma, food allergies, hypersensitivity and anaphylactic re... | 03/02/2004 |
| 6689747 | Use of insulin for the treatment of cartilagenous disorders The present invention relates to methods for the treatment and repair of cartilage, including cartilage damaged by injury or cartilagenous disorders, including arthritis, comprising the administration of insulin and/or insulin variants. Optionally, the ad... | 02/10/2004 |
| 6685939 | Method of preventing the onset of allergic disorders The present invention describes IgE antagonists (including variant anti-IgE antibodies) and their use in diagnosis, therapy or prophylaxis of allergic and other IgE-mediated disorders, including asthma, food allergies, hypersensitivity and anaphylactic re... | 02/03/2004 |
| 6682735 | Anti-IgE antibodies The present invention relates to a method for adjusting the affinity of a polypeptide to a target molecule by a combination of steps, including: (1) the identification of aspartyl residues which are prone to isomerization; (2) the substitution of alternat... | 01/27/2004 |
| 6531579 | Fused polypeptides The present invention relates to nucleotide sequences, including expressed sequence tags (ESTs), oligonucleotide probes, polypeptides, vectors and host cells expressing, immunoadhesins, agonists and antagonists to human & vertebrate fused.... | 03/11/2003 |
| 6492139 | Vertebrate smoothened proteins Novel vertebrate homologues of Smoothened, including human and rat Smoothened, are provided. Compositions including vertebrate Smoothened chimeras, nucleic acid encoding vertebrate Smoothened, and antibodies to vertebrate Smoothened, are also provided.... | 12/10/2002 |
| 6451977 | Fused polypeptides The present invention relates to nucleotide sequences, including expressed sequence tags (ESTs), oligonucleotide probes, polypeptide, vectors and host cells expressing, immunoadhesins, agonists and antagonists to human & vertebrate fused.... | 09/17/2002 |
| 6407216 | Vertebrate smoothened antibodies Novel vertebrate homologues of Smoothened, including human and rat Smoothened, are provided. Compositions including vertebrate Smoothened chimeras, nucleic acid encoding vertebrate Smoothened, and antibodies to vertebrate Smoothened, are also provided.... | 06/18/2002 |
| 6348575 | Patched-2 The present invention relates to nucleotide sequences, including expressed sequence tags (ESTs), oligonucleotide probes, polypeptides, antibodies, vectors and host cells expressing, immunoadhesins, agonists and antagonists to patched-2.... | 02/19/2002 |
| 6329509 | Anti-IgE antibodies Two classes of polypeptides derived from human IgE are described. One class binds selectively to the high affinity IgE receptor on mast cells and basophils, but not to the low affinity IgE receptor on B-cells, monocytes, eosinophils and platelets. The oth... | 12/11/2001 |
| 6290957 | Anti-IgE antibodies and method of improving polypeptides The present invention relates to a method for adjusting the affuinity of a polypeptide to a target molecule by a combination of steps, including: (1) the identification of aspartyl residues which are prone to isomerization; (2) the substitution of alterna... | 09/18/2001 |
| 6284282 | Method of spray freeze drying proteins for pharmaceutical administration The present invention relates to the spray freeze dry preparation of dry powder formulations of therapeutic proteins suitable for administration via pulmonary delivery.... | 09/04/2001 |
| 6172213 | Anti-IgE antibodies and method of improving polypeptides The present invention relates to a method for adjusting the affinity of a polypeptide to a target molecule by a combination of steps, including: (1) the identification of aspartyl residues which are prone to isomerization; (2) the substitution of alternat... | 01/09/2001 |
| 6136958 | Antibodies to vertebrate smoothened proteins Novel vertebrate homologues of Smoothened, including human and rat Smoothened, are provided. Compositions including vertebrate Smoothened chimeras, nucleic acid encoding vertebrate Smoothened, and antibodies to vertebrate Smoothened, are also provided.... | 10/24/2000 |
| 6136569 | Method of creating a cDNA library enriched in signal sequences The present invention relates to a novel method of identifying cDNA's which encode secreted and membrane-bound proteins. The present invention also relates to a novel method for preparing cDNA libraries enriched for signal sequences. The methods of the in... | 10/24/2000 |
| 6100076 | O-fucosyltransferase The present invention describes the identification, purification, recombinant production and characterization of novel O-fucosyltransferase enzymes.... | 08/08/2000 |
| 6060249 | Method of selection for genes encoding secreted and transmembrane proteins The present invention relates to a novel method of identifying cDNA's which encode secreted and membrane-bound proteins. The present invention also relates to a novel method for preparing cDNA libraries enriched for signal sequences. The methods of the in... | 05/09/2000 |
| 6051690 | NSP molecules The present invention relates to nucleotide sequences, including expressed sequence tags (ESTs). oligonucleotide probes, polypeptides, antagonists and agonists vectors and host cells expressing, and immunoadhesions and antibodies to Nsp1, Nsp2 and Nsp3.... | 04/18/2000 |
