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| Number | Title | Issue Date |
| 8105834 | Muscle derived cells for the treatment of urinary tract pathologies and methods of making and using same The present invention provides muscle-derived progenitor cells that show long-term survival following transplantation into body tissues and which can augment soft tissue following introduction (e.g. via injection, transplantation, or implantation) into a site of sof... | 01/31/2012 |
| 7785632 | Thyroid hormone analogs and methods of use Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric form of thyroid hormone, or an antagonist thereof, to promote or inhibit angiogenesis in the subject. Compositions of the ... | 08/31/2010 |
| 7601342 | Cell fusions and methods of making and using the same The invention is concerned with fusions of dendritic cells and antigen presenting cells. Also provided are methods of making and using these cell fusions, including methods of adoptive immunotherapy. The fusions according to the invention can also be used in methods... | 10/13/2009 |
| 7381561 | Enriched central nervous system stem cell and progenitor cell populations, and methods for identifying, isolating and enriching for such populations Enriched neural stem and progenitor cell populations, and methods for identifying, isolating and enriching for neural stem cells using reagents that bind to cell surface markers are provided. ... | 06/03/2008 |
| 7361505 | Multipotent neural stem cell compositions The invention provides in vitro cell culture compositions consisting of neurospheres and culture medium, wherein the neurospheres consist of undifferentiated cells that are nestin+, glial fibrillary acid protein (GFAP)−, neurofilament (NF) | 04/22/2008 |
| 7217565 | Enriched central nervous system stem cell and progenitor cell populations, and methods for identifying, isolating and enriching for such populations Enriched neural stem and progenitor cell populations, and methods for identifying, isolating and enriching for neural stem cells using reagent that bind to cell surface markers, are provided. ... | 05/15/2007 |
| 7211404 | Liver engrafting cells, assays, and uses thereof A substantially enriched mammalian hepatic liver engrafting cell population is provided. Methods are provided for the isolation and culture of this liver engrafting cell. The progenitor cells are obtained from a variety of sources, including fetal and adult tissues.... | 05/01/2007 |
| 7204979 | Generation of hematopoietic cells from multipotent neural stem cells Multipotent neural stem cell (MNSC) progeny are induced to generate cells of the hematopoietic system by placing the MNSC progeny in a hematopoietic-inducing environment. The hematopoietic-inducing environment can be either ex vivo or in vivo. A mammal's circulatory... | 04/17/2007 |
| 7166277 | Remyelination of neurons using multipotent neural stem cell progeny The invention provides methods for producing myelin forming cells from multipotent self-renewing central nervous system neural stem cells as well as methods of using one or more cells from a multipotent self-renewing central nervous system neural stem cell populatio... | 01/23/2007 |
| 7135454 | Use of SLURP-1 compositions for treating schizophrenia Disclosed herein are compositions and methods for the treatment or prevention of neurological disorders. Also disclosed are compositions and methods for the treatment or prevention of skin pathologies. The invention further discloses compositions and methods for the... | 11/14/2006 |
| 7129062 | Matrix attachment regions and methods for use thereof The present invention relates to compositions and methods for transfecting eukaryotic cells with nucleic acid vectors. In particular, the invention relates to the uses of Matrix Attachment Region (MAR) elements to increase stable and transient transfection efficienc... | 10/31/2006 |
| 7115418 | Methods of proliferating undifferentiated neural cells The invention discloses methods of proliferation and differentiation of multipotent neural stem cells. Also provided are methods of making cDNA libraries and methods of screening biological agents which affect proliferation differentiation survival phenotype or func... | 10/03/2006 |
| 7115257 | ARPE-19 as a platform cell line for encapsulated cell-based delivery ARPE-19 cells were evaluated as a platform cell line for encapsulated and unencapsulated cell-based delivery technology. ARPE-19 cells were found to be hardy (the cell line is viable under stringent conditions, such as in central nervous system or intra-ocular envir... | 10/03/2006 |
| 7101709 | Methods of screening biological agents The invention discloses methods of proliferation and differentiation of multipotent neural stem cells. Also provided are methods of making cDNA libraries and methods of screening biological agents which affect proliferation differentiation survival phenotype or func... | 09/05/2006 |
| 7014849 | Keratinocyte culture and uses thereof The present invention relates to the treatment of skin defects by organotypically-cultured autologous keratinocytes isolated from the outer root sheath of anagen or growing hair. Methods for primary, as well as subsequent organotypic cultures (i.e., epidermal equiva... | 03/21/2006 |
| 6924142 | Hypoxia-mediated neurogenesis assay Methods are described for the production of neurons or neuronal progenitor cells. Multipotent neural stem cells are proliferated in the presence of growth factors and erythropoietin which induces the generation of neuronal progenitor cells. The erythropoietin may be... | 08/02/2005 |
| 6878543 | Cultures of GFAP+ nestin+ cells that differentiate to neurons Cultures of cells immunoreactive for glial fibrillary acidic protein (GFAP), as well as for the intermediate filament marker nestin were grown in a medium including epidermal growth factor (EGF) and serum. The cultured cells had the morphology of astroglial cells. T... | 04/12/2005 |
| 6852530 | Self-extinguishing recombinases, nucleic acids encoding them and methods of using the same Nucleic acid molecules comprising at least a first signal site and a recombinase gene operably linked to an expression control sequence, such that upon entry into a cell, there is a first signal site and a second signal site positioned to mediate excision of a suffi... | 02/08/2005 |
| 6721582 | Non-invasive tissue glucose level monitoring Instruments and methods are described for performing non-invasive measurements of analyte levels and for monitoring, analyzing and regulating tissue status, such as tissue glucose levels. ... | 04/13/2004 |
