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| Number | Title | Issue Date |
| 7317070 | Process for the preparation of polyamino acids Among the various aspects of the present invention is an improved process for the preparation of polyamino acids generally, and more specifically, polyglutamic acid and polyaspartic acid. Another aspect is a process for the large scale (i.e. >1 kg) preparation of po... | 01/08/2008 |
| 7294719 | Synthesis of amino acid, N-carboxyanhydrides A process for producing N-carboxyanhydrides is disclosed. The process produces N-carboxyanhydrides as a product and HCl as a by-product. The HCl by-product is purged from the reaction mixture by passing a purge gas through the reaction mixture as a carbonylation rea... | 11/13/2007 |
| 7214484 | Compositions and methods for nucleic acid extraction from biological samples Methods and compositions for extracting nucleic acids from a biological sample are provided. The extraction compositions contain a protease enzyme such as proteinase K at alkaline pH with little or no surfactant present. Extraction can be efficiently performed in 60... | 05/08/2007 |
| 6653530 | Methods for producing carotenoid compounds, tocopherol compounds, and specialty oils in plant seeds Methods are provided for producing plants and seeds having altered carotenoid, fatty acid and tocopherol compositions. The methods find particular use in increasing the carotenoid and tocopherol levels in oilseed plants, and in providing desirable high ol... | 11/25/2003 |
| 6541259 | Nucleic acid sequences to proteins involved in isoprenoid synthesis Nucleic acid sequences and methods are provided for producing plants and seeds having altered tocopherol content and compositions. The methods find particular use in increasing the tocopherol levels in plants, and in providing desirable tocopherol composi... | 04/01/2003 |
| 6506565 | Plant regulatory sequences for selective control of gene expression The present invention relates to nucleic acid sequences for regulating gene expression in plants. In particular, the invention relates to 5' regulatory sequences which are useful for regulating expression of heterologous DNAs in plants and methods for ide... | 01/14/2003 |
| 6444876 | Acyl CoA: cholesterol acyltransferase related nucleic acid sequences By this invention, novel nucleic acid sequences encoding for acyl-CoA: cholesterol acyltransferase (ACAT) related proteins are provided, wherein ACAT-like protein is active in the formation of a sterol ester and/or triacylylgycerol from a fatty acyl-CoA a... | 09/03/2002 |
| 6429356 | Methods for producing carotenoid compounds, and specialty oils in plant seeds Methods are provided for producing plants and seeds having altered carotenoid, fatty acid and tocopherol compositions. The methods find particular use in increasing the carotenoid levels in oilseed plants and in providing desirable high oleic acid seed oi... | 08/06/2002 |
| 6380462 | Method for increasing stearate content in soybean oil This invention relates to a method for increasing stearate as a component of total triglycerides found in soybean seed. The method generally comprises growing a soybean plant having integrated into its genome a DNA construct comprising, in the 5' to 3' di... | 04/30/2002 |
| 6380466 | Production of improved rapeseed exhibiting yellow-seed coat Rapeseed in plants producing rapeseed which have a yellow-seed coat are provided. The yellow-seed coat is controlled by a single locus mutation. Plants from the rapeseed are useful for transferring the trait into elite lines of canola.... | 04/30/2002 |
| 6365802 | Methods for increasing stearate content in soybean oil This invention relates to a method for increasing stearate as a component of total triglycerides found in soybean seed. The method generally comprises growing a soybean plant having integrated into its genome a DNA construct comprising, in the 5' to 3' di... | 04/02/2002 |
| 6171640 | High beta-conglycinin products and their use The utility of soybeans having a composition of greater than 40% of the protein as beta-conglycinin and less than 10% of the protein as glycinin for making highly functional high beta-conglycinin compositions was discovered. The discovered ingredients are... | 01/09/2001 |
| 5693308 | Magnetic resonance blood pool agents bound to human serum albumin The present invention provides compositions comprising a contrast agent capable of reversibly binding to thiol groups of blood-borne proteins. The compositions of the invention provide increased residence time of the contrast agent in the vasculature, thu... | 12/02/1997 |
| 5690908 | Treated apatite particles for medical diagnostic imaging Treated apatite particles are disclosed for enhancing medical diagnostic imaging such as magnetic resonance imaging ("MRI"), magnetic resonance spectroscopy ("MRS"), magnetic resonance spectroscopy imaging ("MRSI"), X-ray diagnostic imaging, and ultrasoun... | 11/25/1997 |
| 5672333 | Delta1,6 bicyclo 4,4,0! functional dyes for contrast enhancement in optical imaging This invention provides functional dyes of the general formula: ##STR1## wherein R1, R2, and R5 may be the same or different and are selected from the group consisting of hydrogen, C1 -C10 alkyl, C1 -C... | 09/30/1997 |
| 5659971 | Aggressive convective drying in an nutsche type filter/dryer The present invention relates to improved drying techniques which increase the capacity and efficiency of agitated pan type dryers. In particular, the present invention relates to a nutsche type filter/dryer apparatus and method for aggressive convective ... | 08/26/1997 |
| 5651956 | Process of preparing coated calcium/oxyanion-containing particles The present invention provides new and structurally diverse particulates for use in magnetic resonance imaging and X-ray contrast imaging of body organs and tissues having the following general formula: Can Mm Xr Ys ... | 07/29/1997 |
| 5648536 | Process for producing ioversol The present invention discloses a new process for producing ioversol (marketed as OPTIRAY.RTM.) comprising: (a) reacting 5-amino-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisopthalamide with chloroacetyl chloride in a polar aprotic solvent, or combination... | 07/15/1997 |
| 5641472 | Tungsten clusters The present invention provides new tri-tungsten compounds of the general structure: ##STR1## wherein R1 is --Ck H1 Zm or --(Ck H1 Zn) (C6 H.sub.(5-q) Zq | 06/24/1997 |
| 5616312 | Thiol ligands and complexes for X-ray imaging The present invention provides new and structurally diverse compositions comprising compounds of the general formula: ##STR1## Wherein R1, R2, R3, R4, and R5 are the same or different and are --C... | 04/01/1997 |
| 5609850 | Treated apatite particles for ultrasound imaging Treated apatite particles are disclosed for enhancing radical diagnostic imaging such as magnetic resonance imaging ("MRI"), magnetic resonance spectroscopy ("MRS"), magnetic resonance spectroscopy imaging ("MRSI"), X-ray diagnostic imaging, and ultrasoun... | 03/11/1997 |
| 5602268 | Process for producing tungsten clusters The present invention provides a process for producing compounds of the general formula: ##STR1## wherein R1 is --Ck Hl Zm or --(Ck Hl Zn)(C6 H.sub.(5-q) Zq | 02/11/1997 |
| 5595724 | Treated calcium/oxyanion-containing particles for medical diagnostic imaging Treated calcium/oxyanion-containing particles are disclosed for enhancing medical diagnostic imaging such as magnetic resonance imaging ("MRI"), magnetic resonance spectroscopy ("MRS"), magnetic resonance spectroscopy imaging ("MRSI"), X-ray diagnostic im... | 01/21/1997 |
| 5565184 | Functionalized tripodal ligands for x-ray & radioactive imaging applications The present invention provides new and structurally diverse compositions comprising compounds of the general formula: ##STR1## wherein A is N or CR1, R1 is hydrogen, C1 -C8 alkyl, or C6 -C10... | 10/15/1996 |
| 5560902 | Microfluidization of radioactive calcium/oxyanion-containing particles Methods of preparing solid apatite particles using a microfluidizer, for use in medical diagnostic imaging such as magnetic resonance imaging, X-ray, and ultrasound. The desired apatite particles are synthesized, passed through a microfluidizer, and purif... | 10/01/1996 |
| 5554749 | Functionalized macrocyclic ligands for imaging applications The present invention provides new and structurally diverse compositions comprising compounds of the general formula: ##STR1## Wherein U is --(CH2)n X or --(CH2)n NR1 (CH2)X; R1 | 09/10/1996 |
| 5546676 | Aggressive convective drying in an agitated pan type dryer The present invention relates to improved drying techniques which increase the capacity and efficiency of agitated pan type dryers. In particular, the present invention relates to an agitated pan type dryer apparatus and method for aggressive convective d... | 08/20/1996 |
| 5544425 | Aggressive convective drying in a nutsche type filter/dryer The present invention relates to improved drying techniques which increase the capacity and efficiency of agitated pan type dryers. In particular, the present invention relates to a nutsche type filter/dryer apparatus and method for aggressive convective ... | 08/13/1996 |
| 5544424 | Aggressive convective drying in a conical screw type mixer/dryer The present invention relates to improved drying techniques which increase the capacity and efficiency of agitated pan type dryers. In particular, the present invention relates to a conical screw type mixer/dryer apparatus and method for aggressive convec... | 08/13/1996 |
| 5520904 | Calcium/oxyanion-containing particles with a polymerical alkoxy coating for use in medical diagnostic imaging The present invention provides new and structurally diverse particulates for use in magnetic resonance imaging and X-ray contrast imaging of body organs and tissues having the following general formula: Can Mm Xr Ys ... | 05/28/1996 |
| 5508388 | Process for manufacturing DTPA-bis amide magnetic resonance imaging Processes for manufacturing diethylenetriaminepentaacetic acid ("DTPA") bis(amide) magnetic resonance imaging ("MRI") agents are disclosed. Specifically, processes for manufacturing [N,N"-Bis[N-(2-methoxyethyl)carbamoylmethyl]diethylenetriamine-N,N',N"-tr... | 04/16/1996 |
| 5489708 | Synthesis of ioversol The reduction of the O-alkyl isomer content of 5-[N-(2-acetoxyethyl)acetoxyacetamido]-N,N'-bis(2,3-diacetoxypropyl)-2,4,6 -triiodoisophthalamide to thereby reduce and/or eliminate the production of impurities comparatively more difficult to remove during t... | 02/06/1996 |
| 5468465 | Treated apatite particles for x-ray diagnostic imaging Treated apatite particles are disclosed for enhancing medical diagnostic imaging such as magnetic resonance imaging ("MRI"), magnetic resonance spectroscopy ("MRS"), magnetic resonance spectroscopy imaging (37 MRSI"), X-ray diagnostic imaging, and ultraso... | 11/21/1995 |
| 5458870 | Compositions for magnetic resonance imaging using a manganese oxalate Methods and diagnostic compositions are disclosed for enhancing magnetic resonance imaging which utilize a paramagnetic metal cluster. Magnetic resonance contrast media containing Z+ [Mn12 X12 (OYR)16l (L)4... | 10/17/1995 |
| 5419892 | Microfluidization of calcium/oxyanion-containing particles Methods of preparing solid apatite particles using a microfluidizer, for use in medical diagnostic imaging such as magnetic resonance imaging, X-ray, and ultrasound. The desired apatite particles are synthesized, passed through a microfluidizer, and purif... | 05/30/1995 |
| 5417959 | Functionalized aza-crytand ligands for diagnostic imaging applications The present invention provides new and structurally diverse compositions comprising compounds of the general formula: ##STR1## Wherein V is CR1 or N; W is CR2 or N; R1 and R2 may be the same or different an... | 05/23/1995 |
| 5417958 | Heavy metal clusters for use as imaging agents The present invention relates to novel compounds for use as imaging agents. In particular, the present invention relates to imaging agents comprising a heavy metal cluster having 2 to 8 atoms of the same of different heavy metal elements, and at least one... | 05/23/1995 |
| 5407659 | Treated calcium/oxyanion-containing particles for medical diagnostic imaging Treated calcium/oxyanion-containing particles are disclosed for enhancing medical diagnostic imaging such as magnetic resonance imaging ("MRI"), magnetic resonance spectroscopy ("MRS"), magnetic resonance spectroscopy imaging ("MRSI"), X-ray diagnostic im... | 04/18/1995 |
| 5405601 | Functionalized tripodal ligands for imaging applications The present invention provides new and structurally diverse compositions for diagnostic imaging comprising compounds of the general formula: ##STR1## wherein A is N or CR1, R1 is hydrogen, C1 -C8 alkyl, or ... | 04/11/1995 |
| 5385724 | Trifluoromethyl analogs of X-ray contrast media for magnetic resonance imaging Methods and compositions are disclosed for enhancing 19 F magnetic resonance imaging which utilize trifluoromethyl derivatives of iodinated X-ray contrast media. Typical magnetic resonance contrast media within the scope of the present inventio... | 01/31/1995 |
