Comic actor Danny Kaye received patent D166,807 for the co-design of "Blowout Toy or the Like". It's similar to one of those toys that unravels when you blow into at a birthday party except Kaye's has three blowouts going in different directions, not just one.
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| Number | Title | Issue Date |
| 7851484 | Certain chemical entities, compositions, and methods Provided are certain chemical entities, and methods of use to modulate skeletal myosin, skeletal actin, skeletal tropomyosin, skeletal troponin C, skeletal troponin I, skeletal troponin T, and skeletal muscle, including fragments and isoforms thereof, as well as the... | 12/14/2010 |
| 6939684 | Motor proteins and methods for their use The invention provides isolated nucleic acid and amino acid sequences of HsKif16a, antibodies to HsKif16a, methods of screening for HsKif16a modulators using biologically active HsKif16a, and kits for screening for HsKif16a modulators. ... | 09/06/2005 |
| 6797484 | Motor proteins and methods for their use The present invention provides high throughput screening system's for identifying compounds useful in the treatment of cellular proliferation disorders. The method can be performed in plurality simultaneously with fluorescence or absorbance readouts. ... | 09/28/2004 |
| 6762043 | Motor proteins and methods for their use The present invention provides high throughput screening systems for identifying compounds useful in the treatment of cellular proliferation disorders. The method can be performed in plurality simultaneously with fluorescence of absorbance readouts. ... | 07/13/2004 |
| 6743897 | Aspergillus fumigatus profilin The invention provides isolated nucleic acid and amino acid sequences of A. fumigatus profilin, methods of screening for A. fumigatus profilin modulators using biologically active A. fumigatus profilin, and kits for screening for A. fumigatus... | 06/01/2004 |
| 6743599 | Compositions and assays utilizing ADP or phosphate for detecting protein modulators Described herein are methods which identify candidate agents as binding to a protein or as a modulator of the binding characteristics or biological activity of a protein. Generally, the methods involve the use of ADP or phosphate. The assays can be used in a high th... | 06/01/2004 |
| 6738716 | Database system for predictive cellular bioinformatics A system for acquiring knowledge from cellular information. The system has a database comprising a database management module (“DBMS”). The system also has a variety of modules, including a population module coupled to the DBMS for categorizing and storing a plu... | 05/18/2004 |
| 6706489 | Motor proteins and methods for their use The invention provides isolated nucleic acid and amino acid sequences of HsKifC2, antibodies to HsKifC2, methods of screening for HsKifC2 modulators using biologically active HsKifC2, and kits for screening for HsKifC2 modulators. ... | 03/16/2004 |
| 6680369 | Motor proteins and methods for their use The invention provides isolated nucleic acid and amino acid sequences of HsKip3, antibodies to HsKip3, methods of screening for HsKip3a modulators using biologically active HsKip3, and kits for screening for HsKip3a modulators.... | 01/20/2004 |
| 6664072 | Kits for screening for modulators of the motor protein HsKip3b The invention provides isolated nucleic acid and amino acid sequences of HsKip3b, antibodies to HsKip3b, methods of screening for HsKip3b modulators using biologically active HsKip3b, and kits for screening for HsKip3b modulators.... | 12/16/2003 |
| 6649363 | Motor proteins and methods for their use The invention provides isolated nucleic acid and amino acid sequences of HsKif12a, antibodies to HsKif12a, methods of screening for HsKif12a modulators using biologically active HsKif12a, and kits for screening for HsKif12a modulators.... | 11/18/2003 |
| 6638754 | Motor proteins and methods for their use The present invention provides high throughput screening systems for identifying compounds useful in the treatment of cellular proliferation disorders. The method can be performed in plurality simultaneously with fluorescence or absorbance readouts.... | 10/28/2003 |
| 6630479 | Methods and compositions utilizing quinazolinones Quinazolinones of formulae 1a, 1b, 1c and 1d are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity. ##STR1##... | 10/07/2003 |
| 6631331 | Database system for predictive cellular bioinformatics A system for acquiring knowledge from cellular information. The system has a database comprising a database management module ("DBMS"). The system also has a variety of modules, including a population module coupled to the DBMS for categorizing and storin... | 10/07/2003 |
| 6627408 | Antifungal assay The present invention provides high throughput screening Systems for identifying antifungal compounds. The method can be performed in plurality simultaneously with fluorescence or absorbance readouts.... | 09/30/2003 |
| 6617144 | Motor proteins and methods for their use The invention provides isolated nucleic acid and amino acid sequences of HsKif16a, antibodies to HsKif16a, methods of screening for HsKif16a modulators using biologically active HsKif16a, and kits for screening for HsKif16a modulators.... | 09/09/2003 |
| 6615141 | Database system for predictive cellular bioinformatics A system for acquiring knowledge from cellular information. The system has a database comprising a database management module ("DBMS"). The system also has a variety of modules, including a population module coupled to the DBMS for categorizing and storin... | 09/02/2003 |
| 6613540 | Methods for screening and therapeutic applications of kinesin modulators The present invention relates to protein modulators, especially modulators of kinesin bioactivities. The present invention provides methods for screening protein modulators, e.g., kinesin modulators that bind to a region of a kinesin and/or that modulate ... | 09/02/2003 |
| 6599694 | Method of characterizing potential therapeutics by determining cell-cell interactions A method quantitatively analyzes images of two different cell types that interact in producing and maintaining a disease state or other biological condition. The two separate cell types are exposed to an agent or stimulus suspected of influencing the biol... | 07/29/2003 |
| 6582958 | Nucleic acids encoding HsKif2x, a human kinesin motor protein The invention provides isolated nucleic acid and amino acid sequences of HsKif2x, antibodies to HsKif2x, methods of screening for HsKif2x modulators using biologically active HsKif2x, and kits for screening for HsKif2x modulators.... | 06/24/2003 |
| 6573061 | Sarcomere protein composition The present invention provides high throughput screening systems for identifying compounds that modulate the biological activity of a biochemically functional sarcomere. The method can be performed in plurality simultaneously with fluorescence or absorban... | 06/03/2003 |
| 6562831 | Methods and compositions utilizing quinazolinones Quinazolinones of formulae 1a, 1b, 1c and 1d are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity. ##STR1##... | 05/13/2003 |
| 6545004 | Methods and compositions utilizing quinazolinones Quinazolinones of formulae 1a, 1b, 1c and 1d are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity. ##STR1##... | 04/08/2003 |
| 6534309 | Motor proteins and methods for their use The invention provides isolated nucleic acid and amino acid sequences of HsKip3d, antibodies to HsKip3d, methods of screening for HsKip3d modulators using biologically active HsKip3d, and kits for screening for HsKip3d modulators.... | 03/18/2003 |
| 6495337 | High throughput sarcomeric assay The present invention provides high throughput screening systems for identifying compounds that modulate the biological activity of a biochemically functional sarcomere. The method can be performed in plurality simultaneously with fluorescence or absorban... | 12/17/2002 |
| 6492151 | Motor proteins and methods for their use The invention provides isolated nucleic acid and amino acid sequences of HsKip3d, antibodies to HsKip3d, methods of screening for HsKip3d modulators using biologically active HsKip3d, and kits for screening for HsKip3d modulators.... | 12/10/2002 |
| 6492158 | Human kinesin protein HsKif6 The invention provides isolated nucleic acid and amino acid sequences of HsKif6, antibodies to HsKif6, methods of screening for HsKif6 modulators using biologically active HsKif6, and kits for screening for HsKif6 modulators.... | 12/10/2002 |
| 6294371 | Motor proteins and methods for their use The invention provides isolated nucleic acid and amino acid sequences of HsKip3b, antibodies to HsKip3b, methods of screening for HsKip3b modulators using biologically active HsKip3b, and kits for screening for HsKip3b modulators.... | 09/25/2001 |
| 6284480 | Antifungal assay The present invention provides high throughput screening systems for identifying antifungal compounds. The method can be performed in plurality simultaneously with fluorescence or absorbance readouts.... | 09/04/2001 |
| 6140493 | Method of synthesizing diverse collections of oligomers A general stochastic method for synthesizing random oligomers can be used to synthesize compounds to screen for desired properties. The use of identification tags on the oligomers facilitates identification of oligomers with desired properties.... | 10/31/2000 |
| 5917016 | Photolabile compounds and methods for their use Novel compounds are provided which are useful as photocleavable linking groups in solid phase synthesis. Compositions incorporating these linking groups and methods for their use are also described.... | 06/29/1999 |
| 5874589 | Methods for synthesizing diverse collections of tetramic acids and derivatives thereof Disclosed are methods for synthesizing very large collections of diverse diverse tetramic acids, tetronic acids, pentamic acids, pentonic acids, and derivatives thereof and synthetic compound libraries comprising compounds prepared by such methods.... | 02/23/1999 |
| 5817751 | Method for synthesis of diketopiperazine and diketomorpholine derivatives The present invention relates to the areas of organic and medicinal chemistry. More specifically, the present invention is concerned with combinatorial and solid phase methods for the synthesis of diverse diketopiperazine derivatives, and the use of such ... | 10/06/1998 |
| 5739386 | Photolabile compounds and methods for their use Novel compounds are provided which are useful as photocleavable linking groups in solid phase synthesis. Compositions incorporating these linking groups and methods for their use are also described.... | 04/14/1998 |
| 5683983 | Peptides and compounds that bind to the IL-5 receptor Described are peptides and peptide mimetics that bind to and the IL-5 receptor. Such peptides and peptide mimetics are useful in methods for treating disorders that involve improper production of or response to IL-5 and or the production and accumulation ... | 11/04/1997 |
| 5677280 | Peptides and compounds that bind to the IL-5 receptor Described are peptides and peptide mimetics that bind to and the IL-5 receptor. Such peptides and peptide mimetics are useful in methods for treating disorders that involve improper production of or response to IL-5 and or the production and accumulation ... | 10/14/1997 |
| 5668110 | Peptides and compounds that bind to the IL-5 receptor Described are peptides and peptide mimetics that bind to and the IL-5 receptor. Such peptides and peptide mimetics are useful in methods for treating disorders that involve improper production of or response to IL-5 and or the production and accumulation ... | 09/16/1997 |
| 5654276 | Peptides and compounds that bind to the IL-5 receptor Described are peptides and peptide mimetics that bind to and the IL-receptor. Such peptides and peptide mimetics are useful in methods for treating disorders that involve improper production of or response to IL-5 and or the production and accumulation of... | 08/05/1997 |
| 5622944 | Testosterone prodrugs for improved drug delivery Compositions and methods are provided for enhanced transdermal electrotransport of 17-hydroxy sterol compounds, including testosterone. The parent sterols are modified at the 17-hydroxy position by covalent attachment of a charged chemical modifier. The c... | 04/22/1997 |
| 5607691 | Compositions and methods for enhanced drug delivery The present invention relates to methods of delivering pharmaceutical agents across membranes, including the skin layer or mucosal membranes of a patient. A pharmaceutical agent is covalently bonded to a chemical modifier, via a physiologically cleavable ... | 03/04/1997 |