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| Number | Title | Issue Date |
| 7217553 | Nucleic acids encoding human adamalysin SVPH1-8 The disclosure provides purified and isolated SVPH1–8 polypeptides, nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against such polypeptide, and fragmented peptides derived from th... | 05/15/2007 |
| 7199224 | Antibodies that bind TNF-α converting enzyme A metalloprotease that converts TNF-α from the 26 kD cell form to the 17 kD form has been isolated and purified and the cDNA sequence known. In particular, the protease has a molecular weight of approximately 80 kD. The isolated and purified protease is useful for ... | 04/03/2007 |
| 7189521 | Claudin polypeptides, polynucleotides, and methods of making and use thereof This invention relates to new members of the human Claudin polypeptide family, to methods of making such polypeptides, and to methods of using them to treat Claudin-associated conditions and to identify agents that alter Claudin polypeptide activities. ... | 03/13/2007 |
| 7186802 | Claudin polypeptides This invention relates to new members of the human Claudin polypeptide family, to methods of making such polypeptides, and to methods of using them to treat Claudin-associated conditions and to identify compounds that alter Claudin polypeptide activities. ... | 03/06/2007 |
| 7175849 | Nectin polypeptides This invention relates to nectin polypeptides and polynucleotides, to methods of making such polypeptides and polynucleotides, and to methods of using such polypeptides and polynucleotides to modulate cell adhesion, cell migration, and angiogenesis, to treat conditi... | 02/13/2007 |
| 7074408 | Use of integrin antagonists to inhibit angiogenesis The present invention provides methods and compositions for inhibiting the biological activity of integrins, for inhibiting endothelial cell migration. and for inhibiting angiogenesis. In particular, the invention provides compositions comprising ADAM disintegrin do... | 07/11/2006 |
| 7041782 | Lectin ss3939 DNA and polypeptides The invention is directed to purified and isolated novel ss3939 polypeptides, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented peptides deriv... | 05/09/2006 |
| 6958387 | Human serpin polypeptides This invention relates to Thypin, a new member of the human serpin polypeptide family, methods of making Thypin polypeptides and using these polypeptides to treat various medical disorders and to methods of screening for compounds that agonize or antagonize Thypin p... | 10/25/2005 |
| 6887687 | Nucleic acids encoding human ataxin-1-like polypeptide IMX97018 This invention relates to IMX97018, a new members of the human ataxin-1-like polypeptide family, methods of making such polypeptides, and to methods of using them to diagnose and treat neurological conditions and to identify compounds that alter IMX97018 polypeptide... | 05/03/2005 |
| 6867013 | Methods of screening for antagonists and agonists of polypeptides having kinase functions The invention is directed to purified and isolated human polypeptides having kinase function, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmente... | 03/15/2005 |
| 6838454 | Carboxylic acid substituted heterocycles, derivatives thereof and methods of use Selected novel carboxylic acid substituted heterocycle compounds are effective for prophylaxis and treatment of inflammation, tissue degradation, cancer, fibrosis and related diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically... | 01/04/2005 |
| 6787644 | Metalloprotease-disintegrin ADAM23 (SVPH3-17) nucleic acids The invention is directed to purified and isolated novel SVPH3-13 or SVPH3-17 polypeptides, the nucleic acids encoding such polypeptides, for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented peptides d... | 09/07/2004 |
| 6759223 | Calcium/calmodulin-dependent kinase The invention is directed to purified and isolated novel murine and human kinase polypeptides, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragment... | 07/06/2004 |
| 6703487 | Human pellino polypeptides There are disclosed novel polypeptides referred to as Pellino polypeptides, as well as fragments thereof, including immunogenic peptides. DNAs encoding such polypeptides as well as methods of using such DNAs and polypeptides are also disclosed.... | 03/09/2004 |
| 6555354 | TNF- converting enzyme A metalloprotease that converts TNF- from the 26 kD cell form to the 17 kD form has been isolated and purified and the cDNA sequence known. In particular, the protease has a molecular weight of approximately 80 kD. The isolated and purified proteas... | 04/29/2003 |
| 6514719 | Methods for identifying compounds that alter kinase activity The invention is directed to purified and isolated novel murine and human kinase polypeptides, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptide... | 02/04/2003 |
| 6406877 | TNF- converting enzyme A metalloprotease that converts TNF- from the 26 kD cell form to the 17 kD form has been isolated and purified and the cDNA sequence known. In particular, the protease has a molecular weight of approximately 80 kD. The isolated and purified proteas... | 06/18/2002 |
| 6406901 | TNF-a converting enzyme A metalloprotease that converts TNF- from the 26 kD cell form to the 17 kD form has been isolated and purified and the cDNA sequence known. In particular, the protease has a molecular weight of approximately 80 kD. The isolated and purified proteas... | 06/18/2002 |
| 6387676 | Human cDNAs encoding polypeptides having kinase functions The invention is directed to purified and isolated human polypeptides having kinase function, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides... | 05/14/2002 |
| 6284237 | Methods of treatment using IL-6 IL-6 is produced via recombinant DNA techniques. The peptide is useful in the treatment of disorders characterized by deficiencies in hematopoietic cells and in combination with other hematopoietins in cancer therapies.... | 09/04/2001 |
