Felix Hoffmann, a German chemist, was searching for something to relieve his father's arthritis. In doing so, he "rediscovered" acetylsalicylic acid and in 1900, patented a stable process for developing it. Hence, we have aspirin.
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| Number | Title | Issue Date |
| 8170666 | Method for scheduling atrial-ventricular conduction checks in minimum ventricular pacing A medical device and associated method deliver cardiac pacing in a dual chamber pacing mode and schedule an atrial-ventricular (AV) conduction check during the dual chamber pacing mode to detect the presence of AV conduction. If AV conduction is detected during the ... | 05/01/2012 |
| 8170663 | Method and apparatus to control delivery of high-voltage and anti-tachy pacing therapy in an implantable medical device A system and method for delivering both anti-tachy pacing (ATP) therapy and high-voltage shock therapy in response to detection of abnormal cardiac rhythms is disclosed. The system controls the time between delivering ATP therapy and the charging of high-voltage cap... | 05/01/2012 |
| 8170654 | Sequential discrimination approach for detecting treatable cardiac rhythms A system and method for use in a medical device for discriminating cardiac events establishes population-based thresholds corresponding to cardiac signal morphology metrics for discriminating between a first cardiac event and a second cardiac event. A population-bas... | 05/01/2012 |
| 8170650 | Implantable tissue perfusion sensing system and method A medical device for sensing cardiac events that includes a plurality of light sources capable of emitting light at a plurality of wavelengths, and a detector to detect the emitted light. A processor generates an ambient light measurement in response to ambient ligh... | 05/01/2012 |
| 8170636 | Optical sensor confidence algorithm An implantable medical device system including an optical sensor monitors for the presence of overgrowth on the sensor by sensing light scattered by a measurement volume, the sensed light corresponding to a first wavelength, and deriving an overgrowth metric in resp... | 05/01/2012 |
| 8165676 | Optical sensor and method for detecting a patient condition An implantable medical device for monitoring tissue perfusion that includes a light source emitting light having a light wavelength corresponding to a blue to ultraviolet light spectrum and a light detector receiving light emitted by the light source and scattered b... | 04/24/2012 |
| 8165662 | Implantable tissue perfusion sensing system and method A medical device for sensing cardiac events that includes a plurality of electrodes sensing cardiac signals utilized to identify a cardiac event, a plurality of light sources capable of emitting light at a plurality of wavelengths, and a detector to detect the emitt... | 04/24/2012 |
| 8160722 | Subcutaneous lead fixation mechanisms A medical device that includes a lead having a lead body extending from a proximal end to a distal end, and a housing having a connector block for receiving the proximal end of the lead body. A fixation mechanism is positioned proximal to an electrode coil located a... | 04/17/2012 |
| 8160684 | Method and apparatus for detecting arrhythmias in a medical device A method of detecting a cardiac event in a medical device that includes sensing cardiac signals from a plurality of electrodes forming a first sensing vector and a second sensing vector, and determining whether the sensing of cardiac signals along the first sensing ... | 04/17/2012 |
| 8145307 | Method and apparatus for enhancing treatable arrhythmia detection specificity by using accumulated patient activity A method and apparatus for detecting a cardiac event in a medical device determine an activity level count from an activity sensor signal for each of a number of time segments, store an activity level count for each of the time segments in a histogram, and accumulat... | 03/27/2012 |
| 8140171 | Subcutaneous implantable lead A subcutaneous implantable device is provided that includes a defibrillation electrode disposed along a portion of a lead, and a lead tip connected to the lead. The lead tip includes a trailing end coupled to a distal end of the lead, and first and second non-parall... | 03/20/2012 |
| 8140156 | Heart sound sensing to reduce inappropriate tachyarrhythmia therapy Techniques for detecting heart sounds to reduce inappropriate tachyarrhythmia therapy are described. In some examples, a medical device determines that a cardiac rhythm of the patient is treatable with a therapy, such as a defibrillation pulse, based on a cardiac el... | 03/20/2012 |
| 8126539 | Method and apparatus for monitoring T-wave alternans An implantable medical device and associated method assess T-wave alternans by sensing a cardiac electrogram (EGM) signal and selecting a pair of consecutive T-wave signals from the EGM signal. A first amplitude and a second amplitude from each of the consecutive T-... | 02/28/2012 |
| 8121682 | Combined hemodynamic and EGM-based arrhythmia detection A medical device and associated method for detecting arrhythmias that includes sensing cardiac electrical signals and cardiac hemodynamic signals, determining a long-term baseline hemodynamic measurement in response to a plurality of the sensed cardiac hemodynaic si... | 02/21/2012 |
| 8118748 | Implantable capacitive pressure sensor system and method Embodiments of the invention provide systems and methods for an implantable capacitive pressure sensor. Some embodiments of the invention include a capacitive pressure sensor capsule comprising a substrate, a conductive plate functionally coupled to the substrate, a... | 02/21/2012 |
| 8111118 | Multi-stable micro electromechanical switches and methods of fabricating same A micro electromechanical (MEMS) switch suitable for use in medical devices is provided, along with methods of producing and using MEMS switches. In one aspect, a micro electromechanical switch including a moveable member configured to electrically cooperate with a ... | 02/07/2012 |
| 8095225 | Robust high power and low power cardiac leads having integrated sensors A lead of an implantable medical device system having an elongated lead body, a sensor coupled to the lead body and extending from a proximal end to a distal end, and a distal lead adaptor having a first arm extending distally from the distal end of the sensor to a ... | 01/10/2012 |
| 8095206 | Method and apparatus for detecting arrhythmias in a medical device A method and apparatus for adjusting a sensing parameter in a medical device that includes a sensing electrode sensing cardiac signals, a processor to determine an adjusting characteristic associated with the cardiac signals sensed over a predetermined sensing windo... | 01/10/2012 |
| 8095205 | Method and apparatus for verifying a determined cardiac event in a medical device based on detected variation in hemodynamic status A method and apparatus for verifying a determined cardiac event in a medical device based on detected variation in hemodynamic status that includes a plurality of sensors sensing cardiac signals, and a physiologic sensor sensing physiologic signals to generate a plu... | 01/10/2012 |
| 8090432 | Implantable tissue perfusion sensing system and method A medical device for sensing cardiac events that includes a plurality of electrodes sensing cardiac signals utilized to identify a cardiac event, a plurality of light sources capable of emitting light at a plurality of wavelengths, and a detector to detect the emitt... | 01/03/2012 |
| 8086307 | Terminating tachyarrhythmias This disclosure is directed to techniques for treating tachyarrhythmias, such as atrial or ventricular fibrillation, in which a number of electrodes are employed to deliver electrical stimulation to a patient's heart in a manner designed to terminate the tachyarrhyt... | 12/27/2011 |
| 8086302 | Cardiac signal sensor control based on perfusion sensing An optical perfusion sensor may monitor blood oxygen saturation of blood-perfused tissue, which may be referred to as tissue perfusion, until a tissue perfusion value is within a threshold range of a reference value, and, in some examples, for at least a minimum per... | 12/27/2011 |
| 8078285 | Reversible implantable acoustic sensor An implantable medical device having an acoustic element includes a control module coupled to the acoustic element, an acoustic sensing module coupled to the control module, and a patient alert driver module coupled to the control circuit. The patient alert driver m... | 12/13/2011 |
| 8078277 | Identification and remediation of oversensed cardiac events using far-field electrograms In general, the disclosure is directed to techniques for identification and remediation of oversensed cardiac events using far-field electrograms (FFEGMs). Identification of oversensed cardiac events can be used in an ICD to prevent ventricular fibrillation (VF) det... | 12/13/2011 |
| 8073537 | Method and apparatus for post-processing of episodes detected by a medical device A system and method for determining oversensing during post-processing of sensing data generated by a medical device that includes transmitting a plurality of stored sensing data generated by the medical device to an access device, the stored sensing data including ... | 12/06/2011 |
| 8073536 | Method and apparatus for post-processing of episodes detected by a medical device A method and system for determining undersensing during post-processing of sensing data generated by a medical device that includes transmitting a plurality of stored sensing data generated by the medical device to an access device, the stored sensing data including... | 12/06/2011 |
| 8068901 | Method and apparatus for adjusting a sensing parameter A method and apparatus of updating a sensing parameter in a medical device that includes sensing cardiac signals, determining intervals in response to the sensed cardiac signals, determining interval patterns associated with the determined intervals, and updating th... | 11/29/2011 |
| 8065007 | Method and apparatus for forming a hermetic enclosure seal in an implantable medical device An implantable medical device that includes a housing having a first shield having an outwardly extending first flange and a second shield having an outwardly extending second flange. The first flange is fixedly engaged with the second flange along a seal to form a ... | 11/22/2011 |
| 8064999 | Distance-based analysis of return cycles for tachycardia discrimination A medical device and associated method classify a tachycardia according to a site of origin of the tachycardia. Cardiac signals are sensed and a tachycardia event is detected in response to the sensed cardiac signals. Pacing pulses are delivered and a time interval ... | 11/22/2011 |
| 8064996 | Automatic determination of T-shock vulnerable window A method and apparatus for determining a T-wave shock interval sense a cardiac electrogram (EGM) signal comprising a T-wave signal. A T-wave center is determined from the EGM signal, and a T-wave shock interval is determined in response to determining the T-wave cen... | 11/22/2011 |
| 8062227 | Heart failure decompensation determination Heart failure decompensation is detected by sensing at least one physiological signal. Values of at least two different heart failure variables are derived using one or more physiological signals and a threshold for the first heart failure variable is adjusted in re... | 11/22/2011 |
| 8057466 | Method and device to form a sensor using isolated cardiomyocytes A method and device are described to form a sensor using a cardiomyocyte by advancing a catheter into the tissue of interest, cardiac in the preferred embodiment, and using the catheter to ablate a cone- or a dome-shaped region to form an electrically isolated secti... | 11/15/2011 |
| 8050759 | Subcutaneous ICD with separate cardiac rhythm sensor A cardiac rhythm sensor positioned on or close to the heart senses electrical or mechanical activity and transmits a cardiac rhythm signal wirelessly to a subcutaneous ICD. Arrhythmia detection and delivery of therapy are performed by the SubQ ICD based upon the car... | 11/01/2011 |
| 8050751 | Periodic beat detection to detect artifacts in a cardiac electrogram Techniques for determining whether artifacts are present in a cardiac electrogram are described. According to one example, a medical device senses a cardiac electrogram via electrodes. The medical device determines a derivative, e.g., a second order derivative, the ... | 11/01/2011 |
| 8050750 | Event discrimination using unipolar and bipolar signal differences A medical device and associated method discriminate near-field and far-field events by sensing a bipolar signal and a unipolar signal at a tissue site, detecting an event in response to one of the bipolar and unipolar signals, and comparing an event feature determin... | 11/01/2011 |
| 8047999 | Filtering of a physiologic signal in a medical device A system and method for filtering a pressure signal in a medical device in which a sensor terminal senses the pressure signal, an electrode terminal receives cardiac electrical signals, a signal filtering system filters the sensed pressure signal in response to a de... | 11/01/2011 |
| 8038626 | Implantable tissue perfusion sensing system and method A medical device system for sensing cardiac events that includes a plurality of electrodes sensing cardiac signals utilized to identify a cardiac event, a plurality of light sources capable of emitting light at a plurality of wavelengths, and a detector to detect th... | 10/18/2011 |
| 8024042 | Minimum ventricular pacing to break the repetitive AR-VS pattern An implantable cardiac pacing device delivering minimum ventricular pacing and an associated method control intervals timed by the device during sensing and pacing. An atrial-only pacing mode is set in response to sensing intrinsic ventricular events in the ventricu... | 09/20/2011 |
| 7991471 | Method and apparatus for detecting arrhythmias in a subcutaneous medical device A method and apparatus for detecting a cardiac event in a medical device that includes sensing cardiac signals from a plurality of electrodes forming a first sensing vector and a second sensing vector, advancing from a first state to a second state in response to pr... | 08/02/2011 |
| 7986994 | Method and apparatus for detecting change in intrathoracic electrical impedance A method and apparatus for detection of changes in impedance a patient that includes generating measured impedances, generating an adaptive baseline trend of the measured impedances corresponding to a first time period, generating a short term trend of the measured ... | 07/26/2011 |