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| Number | Title | Issue Date |
| 7767151 | High throughput mechanical alloying and screening The invention provides an apparatus and methods for conducting ball milling operations in a high throughput manner. Also provided are devices and methods for high throughput screening of alloys and other materials to identify those that have desired gas storage prop... | 08/03/2010 |
| 7638601 | Transient receptor potential channel TRPM8 and its use This invention provides novel genes and polypeptides of the transient receptor potential channel family, and use of these genes and polypeptides for the treatment of pain and identification of agents useful in the treatment of pain. ... | 12/29/2009 |
| 7578206 | Sample deposition method and system A method and system to deposit rapidly, accurately and efficiently liquid droplets onto a sample plate. A liquid from which the droplet is formed contains sample molecules, matrix molecules or a mixture of both sample and matrix molecules. A sample plate is position... | 08/25/2009 |
| 7396910 | Transient receptor potential channel TRPV3 and its use This invention provides novel genes and polypeptides of the transient receptor potential channel family, and use of these genes and polypeptides for the treatment of pain and identification of agents useful in the treatment of pain. ... | 07/08/2008 |
| 7390458 | High throughput processing system and method of using Briefly, the present invention provides a system and method for high throughput processing using sample holders. The system has a plurality of work perimeters, with a rotational robot preferably associated with each work perimeter. At least one transfer station area... | 06/24/2008 |
| 7364907 | Systems and methods for sorting samples Methods and systems for sorting compounds and compound holders into batches for subsequent processing are provided. ... | 04/29/2008 |
| 7344833 | Methods and compositions for modulating activator protein 1 This invention provides novel AP-1 modulatory polypeptides. The invention also provides methods for screening modulators of AP-1 transcription factor activities. The methods comprise first screening test agents for modulators of an AP-1-modulatory polypeptide and th... | 03/18/2008 |
| 7329394 | High throughput incubation devices The invention provides an efficiently automated incubation device that reduces the number of powered moving parts in the device and the amount of air transfer between environments that are internal and external to the device. ... | 02/12/2008 |
| 7329393 | Capacity altering device, holder, and methods of sample processing This invention provides capacity altering devices that facilitate the processing of samples whose volume exceeds the capacity of external sample processing regions (e.g., sample tubes or wells). The invention also provides holders that can be used with such devices,... | 02/12/2008 |
| 7252944 | Methods and compositions for modulating cell proliferation This invention provides methods for identifying novel SHMT modulators. The methods comprise first screening test agents for modulators of p38 activity and then further screening the identified modulating agents for modulators of SHMT enzyme activity. The invention f... | 08/07/2007 |
| 7179619 | Methods and compositions for inhibiting herpesviral replication This invention provides methods of screening for compounds that inhibit herpesviral transcription and replication. The methods comprise screening test compounds for ability to enhance the activity of homeodomain transcription factor PDX1 in repressing transcription ... | 02/20/2007 |
| 7115414 | Vanilloid receptor-related nucleic acids and polypeptides This invention provides novel genes and polypeptides of the VR family, identification of trkA+ pain specific genes expressed in the DRG, and use of these genes and polypeptides for the treatment of pain and identification of agents useful in the treatment... | 10/03/2006 |
| 6964867 | Method and apparatus for performing multiple processing steps on a sample in a single vessel A method is provided for determining crystallization conditions for a protein, the method comprising: performing in a same fermentation apparatus 2 or more separate fermentations where each fermentation comprises cells expressing a protein to be purified and has a f... | 11/15/2005 |
| 6932557 | Gripping mechanisms, apparatus, and methods The present invention provides grasping mechanisms, gripper apparatus/systems, and related methods. Grasping mechanisms that include stops, support surfaces, and height adjusting surfaces to determine three translational axis positions of a grasped object are provid... | 08/23/2005 |
| 6918309 | Sample deposition method and system A method and system to deposit rapidly, accurately and efficiently liquid droplets onto a sample plate. A liquid from which the droplet is formed contains sample molecules, matrix molecules or a mixture of both sample and matrix molecules. A sample plate is position... | 07/19/2005 |
| 6906158 | Compositions and methods of vinyl oxazolone polymerization This invention provides novel methods for synthesis of narrow polydispersity oxazolone-containing polymers via nitroxide-mediated living free radical polymerization, as well as the products and derivatives thereof. ... | 06/14/2005 |
| 6869792 | Method and apparatus for performing multiple processing steps on a sample in a single vessel A method is provided which comprises: performing a plurality of fermentations, each fermentation in a different sample vessel; and performing a further processing step on the plurality of fermented samples where the sample is retained in the same sample vessel as th... | 03/22/2005 |
| 6827113 | Massively parallel fluid dispensing systems and methods The present invention provides highly automated fluid delivery systems and related methods with significantly improved throughput relative to preexisting technologies. In particular, the invention relates to a fluid dispensing system that simultaneously produces mul... | 12/07/2004 |
| 6723555 | Multi-sample fermentor and method of using same A fermentation apparatus is constructed to produce a known and repeatable amount of untainted fermentation product using multiple fermentation vessels. To facilitate further processing compatible with other product processing steps, the fermentation apparatus has an... | 04/20/2004 |
| 6709872 | Method and apparatus for dispensing low nanoliter volumes of liquid while minimizing waste There is provided a method and apparatus for aspirating a volume of liquid into a syringe from a sample of the liquid. A substantial portion of the liquid in the syringe is subsequently dispensed from the syringe and returned to the sample. Accordingly, a small port... | 03/23/2004 |
| 6534014 | Specimen plate lid and method of using The specimen plate lid is generally a block, with a cover portion and a side portion. An alignment protrusion extends from the side portion and cooperates with an alignment member of the specimen plate to assist in manually or roboticly guiding the lid on... | 03/18/2003 |
