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| Number | Title | Issue Date |
| 4207342 | Relieving hypertension with carboxyalkylacylamino acids New carboxyalkylacylamino acids which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.... | 06/10/1980 |
| 4207337 | Relieving hypertension with carboxyalkylacylamino acids New carboxyalkylacylamino acids which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.... | 06/10/1980 |
| 4207336 | Relieving hypertension with carboxyalkylacylamino acids New carboxyalkylacylamino acids which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.... | 06/10/1980 |
| 4206232 | Relieving hypertension with carboxyalkylacylamino acids New carboxyalkylacylamino acids which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.... | 06/03/1980 |
| 4206137 | Thioalkanoylalkanoic acid compounds Thioalkanoylalkanoic acid compounds and salts thereof having the formula ##STR1## wherein R1, R2, R3 and R4 each is hydrogen or lower alkyl; R5 is hydrogen, lower alkanoyl, benzoyl or ##STR2## ... | 06/03/1980 |
| 4206122 | Derivatives of pyrrolidinecarboxaldehyde and piperidinecarboxaldehyde and intermediates therefor Derivatives of pyrrolidinecarboxaldehyde and piperidinecarboxaldehyde, and intermediates therefor, which have the general formula ##STR1## wherein R is hydrogen, lower alkanoyl or ##STR2## R1 is hydrogen or lower alkyl; R2 ... | 06/03/1980 |
| 4206121 | Substituted acyl derivatives of amino acids New substituted acyl derivatives of amino acids which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.... | 06/03/1980 |
| 4202899 | 8H-Pyrazolo[1,5-a]pyrazolo[4',3':5,6]pyrido[3,4-e]pyrimidine New derivatives of 8H-pyrazolo[1,5-a]pyrazolo[4',3':5,6]-pyrido[3,4-e]pyrimidine have the general formula ##STR1## The compounds are useful as anti-inflammatory agents and central nervous system depressants.... | 05/13/1980 |
| 4200649 | Relieving hypertension with carboxyalkylacylamino acids New carboxyalkylacylamino acids which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.... | 04/29/1980 |
| 4199512 | Compounds for alleviating hypertension A method for alleviating or reducing angiotensin related hypertension in hypertensive mammals comprises administering to such hypertensive mammals an effective amount of an angiotensin converting enzyme inhibitor selected from a group of mercaptoacyl amin... | 04/22/1980 |
| 4198515 | Mercaptoacyl derivatives of 4,5-dihydro-1H-pyrrole-2-carboxylic acids and 1,4,5,6-tetrahydropyridine-2-carboxylic acids New mercaptoacyl derivatives of 4,5-dihydro-1H-pyrrole-2-carboxylic acids and 1,4,5,6-tetrahydropyridine-2-carboxylic acids having the general formula ##STR1## are useful as hypotensive agents.... | 04/15/1980 |
| 4198509 | Mercaptoacylpiperazine carboxylic acid compounds The mercaptoacylpiperazine carboxylic acid compounds which have the formula ##STR1## wherein R, R3 and R4 each is hydrogen or lower alkyl; R1 is lower alkyl; R2 is hydrogen, lower alkanoyl, benzoyl or ##STR2## ... | 04/15/1980 |
| 4192882 | Carboxyalkylacylamino acids New carboxyalkylacylamino acids which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors. The compounds claimed in this application are those wherein R1 is 3-indolyl-lower alkylene.... | 03/11/1980 |
| 4192881 | Carboxyalkylacyl substituted imidazolylamino acids New carboxyalkylacylamino acids which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.... | 03/11/1980 |
| 4180579 | 2-Substituted-1H-benz[de]-isoquinoline-1,3(2H)-diones Compounds of the following formula ##STR1## wherein R1 and R2 are independently selected from hydrogen, halogen, lower alkyl, lower alkoxy, lower alkylthio, nitro, cyano, and trifluoromethyl, and R is selected from a triacetyl s... | 12/25/1979 |
| 4177277 | Method for alleviating hypertension A method for alleviating or reducing angiotensin related hypertension in hypertensive mammals comprises administering an effective amount of a compound having the general formula ##STR1## Intermediates for the preparation of such compounds are also i... | 12/04/1979 |
| 4176235 | Substituted acyl derivatives of amino acids New substituted acyl derivatives of amino acids which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.... | 11/27/1979 |
| 4175199 | Substituted acyl derivatives of amino acids New substituted acyl derivatives of amino acids which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.... | 11/20/1979 |
| 4174442 | Substituted hydrazino derivatives of benzisothiazole-1,1-dioxides Compounds which have the general formula ##STR1## and those which can be obtained from them with a Vilsmeier type reagent and have the formula ##STR2## as well as salts thereof, are useful as anti-inflammatory agents.... | 11/13/1979 |
| 4173704 | Dithio aminoacid derivatives A method for alleviating or reducing angiotensin related hypertension in hypertensive mammals comprises administering to such hypertensive mammals an effective amount of an angiotensin converting enzyme inhibitor selected from a group of mercaptoacyl amin... | 11/06/1979 |
| 4171435 | [(Thioalkyl)thioacetyl)]cephalosporin derivatives [(Thioalkyl)thioacetyl]cephalosporin derivatives of the formula ##STR1## wherein R is hydrogen, lower alkyl, phenyl-lower alkyl, tri(lower alkyl)silyl, a salt forming ion, or the group ##STR2## R1 is hydrogen, lower alkyl, phenyl, thi... | 10/16/1979 |
| 4170651 | 2-Substituted-1H-benz-[de]-isoquinoline-1,3(2H)-diones Compounds of the following formula ##STR1## wherein R1 and R2 are independently selected from hydrogen, halogen, lower alkyl, lower alkoxy, lower alkylthio, nitro, cyano, and trifluoromethyl, and R is selected from a triacetyl s... | 10/09/1979 |
| 4169946 | Reactions of thiooxime cephalosporin and penicillin derivatives Compounds of the formula ##STR1## wherein A is ##STR2## R is hydrogen, lower alkyl, benzyl, p-methoxybenzyl, p-nitrobenzyl, diphenylmethyl, tri(lower alkyl)silyl, lower alkoxymethyl, 2,2,2-trichloroethyl, ##STR3## Y is halogen or ... | 10/02/1979 |
| 4168267 | Phosphinylalkanoyl prolines New phosphinylalkanoyl prolines which have the general formula ##STR1## wherein R1 is lower alkyl, phenyl or phenyl-lower alkyl; R2 is hydrogen, phenyl-lower alkyl or a metal ion; R3 is hydrogen or lower alkyl; R4 is... | 09/18/1979 |
| 4168266 | 6-[[[(2-Cyanomethyl)amino]-1,2-dioxoethyl]-amino]acyl penicillins 6-[[[(2-Cyanomethyl)amino]-1,2-dioxoethyl]amino]acyl pencillins which have the formula ##STR1## wherein R is hydrogen, lower alkyl, tri(lower alkyl)silyl, tri(lower alkyl)stannyl, trihaloethyl or a salt forming ion; R1 is hydrogen, lo... | 09/18/1979 |
| 4166134 | Method for improving flexibility retention of chewing gum A method is provided for improving flexibility retention of chewing gum which contains gum base, aqueous softener such as corn syrup, sucrose, and a humectant such as sorbitol includes separating the aqueous softener from the humectant by incorporating th... | 08/28/1979 |
| 4156786 | Amino acid derivatives New substituted acyl derivatives of amino acids which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.... | 05/29/1979 |
| 4156723 | Perhydro naphthalene pentol derivatives Compounds are provided having the structure ##STR1## wherein R1, R2, R3 or R4 is hydrogen or acyl, and R5 is hydrogen or acyl, X is a straight or branched bivalent alkylene radical and Y is ... | 05/29/1979 |
| 4156084 | Certain dimers of tetrahydropyridine-2-carboxylic acids or pyrroline-2-carboxylic acids and derivatives thereof New compounds which have the general formula ##STR1## are useful as hypotensive agents.... | 05/22/1979 |
| 4156006 | Vinyl sulfide derivatives of benzimidazoles Vinyl sulfide derivatives of benzimidazoles are provided having the structure ##STR1## wherein R is lower alkyl or phenyl-lower alkyl, R1 is lower alkyl, R2 is hydrogen or lower alkyl, or R1 and R2 may be t... | 05/22/1979 |
| 4155905 | 6-Substituted penicillanic acid and derivatives thereof Disclosed herein are penicillanic acids and derivatives thereof which are substituted in the 6-position, processes for preparing such compounds and the utility thereof. The compounds of the invention have been found to be useful as antibacterial agents.... | 05/22/1979 |
| 4154946 | Amino mercapto substituted acylamino acids New substituted acyl derivatives of amino acids which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.... | 05/15/1979 |
| 4154934 | Mercaptoacylamino derivatives of heterocyclic carboxylic acids New mercaptoacyl derivatives of heterocyclic carboxylic acids which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.... | 05/15/1979 |
| 4154935 | Halogen substituted mercaptoacylamino acids New halogen substituted mercaptoacylamino acids which have the general formula ##STR1## ARE USEFUL AS HYPOTENSIVE AGENTS.... | 05/15/1979 |
| 4154936 | Substituted acyl derivatives of amino acids New substituted acyl derivatives of amino acids which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.... | 05/15/1979 |
| 4154937 | Hydroxycarbamoylalkylacylpipecolic acid compounds New hydroxycarbamoylalkylacyl derivatives of pipecolic acid which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.... | 05/15/1979 |
| 4154942 | Certain tetrahydropyridine-2-carboxylic acids and pyrroline-2-carboxylic acids and derivatives thereof New compounds which have the general formula ##STR1## are useful as hypotensive agents.... | 05/15/1979 |
| 4154960 | Amino acid derivatives New substituted acyl derivatives of amino acids which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.... | 05/15/1979 |
| 4154736 | Indolylalkylene amino acid derivatives New derivatives of amino acids which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.... | 05/15/1979 |
| 4154840 | Antihypertensive pipecolic acid derivatives New proline derivatives and related compounds which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.... | 05/15/1979 |
