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Attorney: Smith; Glenn D.


Number of patents: 55
Last date: March 20, 2012

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NumberTitleIssue Date
8138290High water content ophthalmic devices
An ophthalmic device is disclosed that is a polymerization product of a monomeric mixture comprising (a) a major amount of a non-silicone-containing hydrophilic monomer; (b) a hydrophobic monomer; and (c) a crosslinking agent, wherein the ophthalmic device has an eq...
03/20/2012
8138288Synthesis of cationic siloxane prepolymers
This application is directed toward an improved method of synthesizing cationic siloxane prepolymers as well as a specific cationic siloxane prepolymer having improved compatibility with monofunctional siloxanyl methacrylate monomers and medical devices containing t...
03/20/2012
8133960Biomedical devices
Biomedical devices such as contact lenses formed from a polymerization product of a mixture comprising (a) a random copolymer comprising hydrophilic units and hydrophobic units, wherein the random copolymer has at least one thio carbonyl thio fragment of a reversibl...
03/13/2012
8133512Drug delivery systems based on catonic siloxanyl macromonomers
Matrix controlled diffusion drug delivery systems based on one or more silicon-containing monomers of the general formula: wherein L, X−, n, R1, R2, R3, R4, R5, R6, R7 and V are as set forth herein. ...
03/13/2012
8133511Drug delivery system based on cationic siloxanyl macromonomers
Matrix controlled diffusion drug delivery systems are described herein which are based on one or more silicon-containing monomers of the general formula: wherein L, X−, n, R1, R2, R3, R4, R5, R6, R7 and V are a...
03/13/2012
8119753Silicone hydrogels with amino surface groups
A silicone hydrogel comprising monomeric units of one or more amino monomers, wherein the amino monomers are of formula IA, IB, IIA or IIB and monomeric units of one or more silicone monomers wherei...
02/21/2012
8105623Fluorinated poly(ether)s end-capped with polymerizable cationic hydrophilic groups
The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain cationic monomers capable of polymerization to form polymeric compositions having desirabl...
01/31/2012
8105070Apparatus and method for releasing a lens molded in a cavity between posterior and anterior mold sections
An apparatus and method for releasing a lens moulded in a cavity between posterior (21) and anterior mould (22) sections and adhered thereto. A post (30) is configured to support a flange (20) of the posterior section whilst the anterior ...
01/31/2012
8101698Surface active prepolymers with both fluorine-containing groups and hydrophilic groups
Provided are surface modified contact lenses formed from one or more fumaric-or itaconic-containing prepolymers having polymerizable functionality that is complimentary to polymerizable hydrophilic polymers. ...
01/24/2012
8100528Coating solutions comprising segmented interactive block copolymers
This invention is directed toward surface treatment of a device. The surface treatment comprises the attachment of interactive segmented block copolymers to the surface of the substrate by means of interactive functionalities of the segmented block copolymer reactin...
01/24/2012
8083348Biomedical devices
Biomedical devices such as contact lenses formed from a polymerization product of a mixture comprising an ethylenically unsaturated-containing non-amphiphilic macromonomer comprising hydrophilic units or hydrophobic units derived from a living radical polymerization...
12/27/2011
8071704Prepolymerizable surface active monomers with both fluorine-containing groups and hydrophilic groups
Provided are surface modified contact lenses formed from one or more fumaric- or itaconic-containing prepolymers having reactive functionality that is complimentary to surface modifying polymers. ...
12/06/2011
8043369Biomedical devices
Biomedical devices such as silicone hydrogels formed from a polymerization product of a mixture comprising (a) a siloxane-containing homopolymer comprising one or more thio carbonyl thio fragments of a reversible addition fragmentation chain transfer (RAFT) agent; a...
10/25/2011
8038912Method and apparatus for the dry release of a compliant ophthalmic article from mold surface
An apparatus for releasing a molded lens from a deformable mold includes a shear ring for temporarily retaining an annular portion of the deformable mold outside a periphery of the lens and a plunger for deforming an annular section of the deformable mold within the...
10/18/2011
8030423Multi-armed macromonomers
Multi-armed macromonomers containing multiple side chains attached to a siloxy-containing core terminated on each end with one or more first substantially linear polysiloxane radicals having a polymerizable ethylenically unsaturated-containing terminal group, wherei...
10/04/2011
7994356Mono ethylenically unsaturated polycarbosiloxane monomers
The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain monoethylenically unsaturated polycarbosiloxane monomers capable of polymerization to form...
08/09/2011
7960447Cationic end-capped siloxane prepolymer for reduced cross-link density
The present invention relates to hydrophilic dicationic siloxane prepolymers with one polymerizable vinyl moiety instead of two polymerizable vinyl moieties, resulting in contact lenses and/or biomedical devices with reduced cross-link density and modulus without de...
06/14/2011
7951897Synthesis of cationic siloxane prepolymers
This application is directed toward an improved method of synthesizing cationic siloxane prepolymers as well as a specific cationic siloxane prepolymer having improved compatibility with monofunctional siloxanyl methacrylate monomers and medical devices containing t...
05/31/2011
7942929Coating solutions comprising segmented reactive block copolymers
This invention is directed toward surface treatment of a device. The surface treatment comprises the attachment of reactive segmented block copolymers to the surface of the substrate by means of reactive functionalities of the terminal functionalized surfactant mate...
05/17/2011
7935770Surface active prepolymers with both fluorine-containing groups and hydrophilic groups
Provided are surface modified contact lenses formed from one or more fumaric- or itaconic-containing prepolymers having polymerizable functionality that is complimentary to polymerizable hydrophilic polymers. ...
05/03/2011
7935280Core locking assembly and method for orientation of asymmetric tooling
An apparatus and method is provided for injection molding an ophthalmic lens mold section having an optical surface and a non-optical surface opposite the optical surface. The apparatus includes a non-optical tool assembly for forming the non-optical surface of the ...
05/03/2011
7934830High water content silicone hydrogels
Silicone hydrogels formed from a hydrated polymerization product of a monomer mixture comprising (a) a major amount of a non-silicone-containing hydrophilic monomer; and (b) a minor amount of a silicone-containing monomer, wherein the hydrogel has a water content of...
05/03/2011
7915323Mono ethylenically unsaturated polycarbosiloxane monomers
The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain monoethylenically unsaturated polycarbosiloxane monomers capable of polymerization to form...
03/29/2011
7837934Packaging solutions
Packaging systems for storing ophthalmic devices such as contact lenses and to methods for packaging such ophthalmic devices with solutions to improve the comfort of the lenses during wear are disclosed. A packaging system includes an ophthalmic device stored in an ...
11/23/2010
7832188Apparatus and method for sealing a lidstock to a container
The invention relates to a method for heat sealing a lidstock (9) to a container (1) for a blister package, the container having a top surface comprising a substantially flat sealing flange (3) surrounding a blister (2) and a lip (4
11/16/2010
7825273Process for making cationic hydrophilic siloxanyl monomers
The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain cationic monomers capable of polymerization to form polymeric compositions having desirabl...
11/02/2010
7781558Hydrophilic siloxanyl monomers with pendant polymerizable groups
The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain hydrophilic monomers capable of polymerization to form polymeric compositions having desir...
08/24/2010
7759408Silicon-containing monomers end-capped with polymerizable cationic hydrophilic groups
The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain cationic monomers capable of polymerization to form polymeric compositions having desirabl...
07/20/2010
7745564System for synthesis of device forming monomers
Disclosed in embodiments herein is a method of synthesizing device forming monomers using N-(Vinyloxycarbonyloxy)succinimide. ...
06/29/2010
7732546Use of silylated sulfonate monomers to improve contact lens wettability
The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain hydrophilic monomers capable of polymerization to form polymeric compositions having desir...
06/08/2010
7622512Cationic hydrophilic siloxanyl monomers
The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain cationic monomers capable of polymerization to form polymeric compositions having desirabl...
11/24/2009
7601766Carboxylic siloxanyl monomers with pendant polymerizable groups
The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain carboxylic monomers capable of polymerization to form polymeric compositions having desira...
10/13/2009
7585167Core locking assembly and method for orientation of asymmetric tooling
An apparatus and method is provided for injection molding an ophthalmic lens mold section having an optical surface and a non-optical surface opposite the optical surface. The apparatus includes a non-optical tool assembly for forming the non-optical surface of the ...
09/08/2009
7579021Drug delivery systems based on degradable cationic siloxanyl macromonomers
Matrix controlled diffusion drug delivery systems based on one or more silicon-containing monomers of the general formula: wherein L, X−, n, R1, R2, R3, R4, R5, R6, R7 and V are as set forth herein. ...
08/25/2009
7557231Carboxylic tris-like siloxanyl monomers
The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain carboxylic monomers capable of polymerization to form polymeric compositions having desira...
07/07/2009
7544371Drug delivery systems
Matrix controlled diffusion drug delivery systems based on one or more silicone-containing monomers of the general formula: wherein x, y, m, m′, R, R1, R2, R3, R4, R5...
06/09/2009
7528208Siloxane prepolymer containing pendant and end-capping cationic and polymerizable groups
The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain cationic random copolymers capable of polymerization to form polymeric compositions having...
05/05/2009
7482416Prepolymers for improved surface modification of contact lenses
Provided are a novel class of fumaric- and itaconic-containing prepolymers and compositions comprising the prepolymers used in the manufacture of medical devices. ...
01/27/2009
7468397Polymerizable siloxane-quaternary amine copolymers
The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain cationic monomers capable of polymerization to form polymeric compositions having desirabl...
12/23/2008
7411029Prepolymers for improved surface modification of contact lenses
Provided are a novel class of fumaric- and itaconic-containing prepolymers and compositions comprising the prepolymers used in the manufacture of medical devices. ...
08/12/2008
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