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| Number | Title | Issue Date |
| 8177803 | Endoscopic cutting instruments having improved cutting efficiency and reduced manufacturing costs The present invention is directed to improving the cutting efficiency and reducing the manufacturing costs associated with endoscopic cutting instruments by eliminating the distal bearing surfaces or providing means for making the contact at the distal bearing inter... | 05/15/2012 |
| 8177784 | Electrosurgical device having floating potential electrode and adapted for use with a resectoscope Disclosed herein are embodiments of an electrosurgical device that include one or more floating electrodes and are specifically adapted to remove, cut, resect, ablate, vaporize, denaturize, drill, coagulate and form lesions in soft tissues, with or without externall... | 05/15/2012 |
| 7993355 | Method and device for suture isolation A method and device provides features for the temporary “parking” of sutures with respect to a cannula. In the preferred embodiments the features are slots that maintain tension on, and orientation of, sutures placed therein. The slots or features may be integra... | 08/09/2011 |
| 7922744 | Compact suture punch with malleable needle A suture punch system that is capable of directly passing braided suture through tissue in a simple, one-step process. The system includes three principle components: a malleable needle capable of delivering the suture to the tissue, a handheld instrument for graspi... | 04/12/2011 |
| 7863420 | Process for removing fibronectin from plasma fractions The invention relates to a method for separating fibronectin from plasma fractions by adjusting a pH value of less than 5.4 such that fibronectin is precipitated and extracted from the solution. ... | 01/04/2011 |
| 7789836 | System, method, and kit for positioning a monitor transducer on a patient An improved patient monitoring system is described herein. In particular, the present invention provides an improved system, method, and kit for positioning and removably mounting, often repeatedly, a monitor transducer on a patient, for example, an external fetal m... | 09/07/2010 |
| 7786156 | Synthesis methods and intermediates for the manufacture of Rizatriptan The invention relates to a process for the manufacture of an 1,2,4-triazol-1-yl compound of the formula [A], or a salt thereof, wherein each of R3 and R4 is hydrogen or lower alkyl, said process comprising reacting a hydraz... | 08/31/2010 |
| 7785629 | Bicalutamide-adsorbates, process for preparing same, and pharmaceutical compositions thereof The present invention relates to an adsorbate, comprising an adsorbent and bicalutamide adsorbed on said adsorbent, a process for preparing same, and a pharmaceutical composition thereof. ... | 08/31/2010 |
| 7777049 | Crystalline forms of Rizatriptan benzoate The present invention is directed to the novel polymorphic Form A and Form B of Rizatriptan benzoate, processes for the preparation thereof and pharmaceutical compositions comprising these crystalline forms. ... | 08/17/2010 |
| 7771419 | Biomedical dispersive electrode Herein is disclosed a biomedical dispersive electrode which can redistribute the current in the subject body, increase subject safety, reduce the chance for burns and other tissue damage as well as discomfort experienced by subject during or after usage. Electrodes ... | 08/10/2010 |
| 7735573 | Lawn perforating tool and method of using same Disclosed herein is a lawn perforating tool and method of using same to prepare new lawn or garden areas or distressed regions of existing lawns or gardens for the planting of seed, example of which include, but are not limited to, grass seed, clover seed, wildflowe... | 06/15/2010 |
| 7699856 | Method, apparatus, and kit for thermal suture cutting A novel suture removal instrument, kit and technique are described herein. The invention utilizes a newly designed thermal filament to allow the tip of the suture removal instrument to be slipped under the stitch in order to heat and cut the stitch. Current suture r... | 04/20/2010 |
| 7687083 | Pharmaceutical compositions comprising old man's beard () and St. John's wort () and their use Pharmaceutical compositions of Usnea barbata and the use thereof for the treatment of skin diseases are disclosed. A preferred composition is the combination with an extract of Hypericum perforatum. The extracts are obtained by supercritical high-press... | 03/30/2010 |
| 7666200 | Endoscopic cutting instrument with axial and rotary motion Disclosed herein is an endoscopic surgical assembly having improved cutting efficiency. In particular, the present invention provides an endoscopic shaver assembly configured for automated axial as well as rotational motion so as to enhance tissue resection. ... | 02/23/2010 |
| 7637526 | Sliding coating for winter sports equipment According to the invention, a sliding coating for winter sports equipment which is a blend of a copolymer (I) and a copolymer (II) is provided, the copolymer (I) being a propylene copolymer which contains at least 50% of structural building blocks which originate fr... | 12/29/2009 |
| 7608633 | Heteroaryl-substituted acetone derivatives as inhibitors of phospholipase A The invention relates to novel heteroaryl substituted acetone derivatives which inhibit the enzyme phospholipase A2, pharmaceutical preparations containing these compounds and a method of producing these compounds. ... | 10/27/2009 |
| 7566333 | Electrosurgical device with floating-potential electrode and methods of using the same The present invention relates to electrosurgical probes suitable for tissue vaporization and cutting of tissue structures, more particularly for performing electrosurgical cutting, ablation (volumetric tissue vaporization), coagulating and/or modification within a b... | 07/28/2009 |
| 7563261 | Electrosurgical device with floating-potential electrodes An electrosurgical instrument, system and methods are provided for the vaporization, cutting, coagulation, or treatment of tissue in the presence of an electrically conductive fluid medium. The electrosurgical probe comprises at least one active electrode, and at le... | 07/21/2009 |
| 7507827 | Stereoselective method for the production of Clopidogrel The present invention relates to processes for preparing a compound of the general formula (Ia) wherein X is a halogen atom, or a pharmaceutically acceptable salt thereof, wherein a compound of the formula (II) | 03/24/2009 |
| 7495081 | Framework patched anti-CD20 antibody Framework (FR)-patching is a novel approach to modify immunoglobulin for reducing potential immunogenicity without significant alterations in specificity and affinity. Unlike previous described methods of humanization, which graft CDRs from a donor onto the framewor... | 02/24/2009 |
| 7491514 | Reducing the immunogenicity of anti-CD20 antibodies by framework patching Framework (FR)-patching is a novel approach to modify immunoglobulin for reducing potential immunogenicity without significant alterations in specificity and affinity. Unlike previous described methods of humanization, which graft CDRs from a donor onto the framewor... | 02/17/2009 |
| 7491396 | Process for the preparation of hypoallergenic mosaic antigens A process for the preparation of an hypoallergenic mosaic antigen derived from an allergen is disclosed whereby a) in a first step the allergen is split into at least two parts and the IgE reactivity of each part is determined and b) in a second step those parts of ... | 02/17/2009 |
| 7468351 | Erythropoietin solution formulation A stable pharmaceutical formulation of erythropoietin is disclosed which contains tris-(hydrox-ymethyl)-aminomethane as stabilizer, whereby the formulation does not contain amino acids or human serumalbumin. ... | 12/23/2008 |
| 7414126 | Process for the preparation of topiramate The present invention relates to a process for the preparation of topiramate, intermediates in this process and a process for the preparation of these intermediates. ... | 08/19/2008 |
| 7338659 | Reducing immunogenicities of immunoglobulins by framework-patching Framework (FR)-patching is a novel approach to modify immunoglobulin for reducing potential immunogenicity without significant alterations in specificity and affinity. Unlike previous described methods of humanization, which graft CDRs from a donor onto the framewor... | 03/04/2008 |
| 7321026 | Framework-patched immunoglobulins Framework (FR)-patching is a novel approach to modify immunoglobulin for reducing potential immunogenicity without significant alterations in specificity and affinity. Unlike previous described methods of humanization, which graft CDRs from a donor onto the framewor... | 01/22/2008 |
| 7198609 | Method for splinting rib injuries A method for splinting rib injuries is disclosed. A pair of anchor strips having a plurality of fasteners on their exposed surfaces are attached to the skin of the chest cavity by an adhesive, the strips being more or less vertically oriented and equidistantly space... | 04/03/2007 |
| 7118871 | Reagents for monitoring nucleic acid amplification and methods of using same Described herein are novel indicator molecules of general formula (1): wherein Q, F, N, Nuc, X1 and X2 are as defined herein, including their tautomeric forms and their additive salts. The p... | 10/10/2006 |
| 7101685 | Recombinant Sendai virus A method for generating Sendai virus particles by transfecting the Sendai virus genome to a host expressing all genes for the initial viral replication has been developed, enabling the genetic manipulation of Sendai virus and effective utilization of said virus as t... | 09/05/2006 |
| 7004918 | Low cost orthosis for toe injuries A low-cost orthosis for the treatment of toe injuries is disclosed. The orthosis is a bilateral, monolithic structure molded from polymeric foam material and having an upper portion adapted to surround the heel, dorsal portions, and toes of a foot, and a lower porti... | 02/28/2006 |
| 6971995 | Method for splinting rib injuries A method for splinting rib injuries is disclosed. A pair of anchor strips having a plurality of fasteners on their exposed surfaces are attached to the skin of the chest cavity by an adhesive, the strips being more or less vertically oriented and equidistantly space... | 12/06/2005 |
| 6955660 | Internal expansion syringe adaptor An adaptor for connecting a syringe to an aspiration and/or irrigation device, typically a medical device such as a catheter, cannula or needle, is described herein. The adaptor is comprised of two components: a deformable elastomeric expansion sleeve and a relative... | 10/18/2005 |
| 6723532 | Negative strand RNA viral vector having autonomous replication capability A method for reconstituting Sendai viral particles by transfecting Sendai virus to a host expressing all genes for the initial replication has been developed, enabling the Production of negative strand RNA vectors highly useful for practical applications. ... | 04/20/2004 |
| 6645760 | Negative strand RNA viral vector having autonomous replication capability A method for reconstituting Sendai viral particles by transfecting Sendai virus to a host expressing all genes for the initial replication has been developed, enabling the production of negative strand RNA vectors highly useful for practical applications.... | 11/11/2003 |
| 6562864 | Catechin multimers as therapeutic drug delivery agents Described herein are catechin multimers, and particularly substituted catechin multimers, and their use as carrier moieties for the delivery of nucleophilic and cationic bioactive therapeutic agents to target sites in vivo. For example, substituted catech... | 05/13/2003 |
| 6557492 | System for transporting and storing live fish, components thereof and methods based thereon A live fish transport system is described herein. In particular, a modular live fish transport tote, an oxygen delivery system, an automated water treatment and delivery apparatus, and a chemically and biologically balanced aquaculture solution are descri... | 05/06/2003 |
| 6423742 | Compositions for reducing vascular plaque formation and methods of using same Described herein are novel, therapeutic pharmaceutical and nutraceutical compositions useful for treating stenotic vascular diseases and disorders, such as atherosclerosis and coronary artery disease, and reducing formation of plaque on vascular walls and... | 07/23/2002 |
| 5906809 | One-step method and preparation for reducing dentinal hypersensitivity A highly acidic oxalate ion-containing preparation, which includes a neuroactive substance, for reducing tooth hypersensitivity, and a method for using same are disclosed.... | 05/25/1999 |
| 5874066 | Method and kit for treating tooth hypersensitivity A two-step method for treating tooth hypersensitivity so as to prevent, reduce or eliminate the same, and a kit for use in the same, are disclosed.... | 02/23/1999 |
