...When G.G. Hubbard learned of his future son-in-law's invention, he called it "only a toy." His daughter was engaged to a young man named Alexander Graham Bell.
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| Number | Title | Issue Date |
| 8039640 | Morphine compounds for pharmaceutical compositions The invention relates to new morphine compounds of the formula: where R1 represents a C1-6 alkyl radical and the radicals R2 and R3 are independently selected from the group consi... | 10/18/2011 |
| 8038634 | Sternotomy splinting assembly, kit and method for use Herein disclosed is a simple, passive splinting system for sternotomy patients designed to provide a continuous yet readily adjustable, compressive tangential stabilizing force to the ribcage so as to promote healing of a median sternotomy incision while minimizing ... | 10/18/2011 |
| 8033341 | Lawn perforating tool and method of using same Disclosed herein is a lawn perforating tool and method of using same to prepare new lawn or garden areas or distressed regions of existing lawns or gardens for the planting of seed, example of which include, but are not limited to, grass seed, clover seed, wildflowe... | 10/11/2011 |
| 7993355 | Method and device for suture isolation A method and device provides features for the temporary “parking” of sutures with respect to a cannula. In the preferred embodiments the features are slots that maintain tension on, and orientation of, sutures placed therein. The slots or features may be integra... | 08/09/2011 |
| 7735573 | Lawn perforating tool and method of using same Disclosed herein is a lawn perforating tool and method of using same to prepare new lawn or garden areas or distressed regions of existing lawns or gardens for the planting of seed, example of which include, but are not limited to, grass seed, clover seed, wildflowe... | 06/15/2010 |
| 7722906 | Polyunsaturated fatty acid fractions of L. seeds The present invention provides novel compositions comprising a Nigella sativa L. polyunsaturated fatty acid fraction. The present invention also provides novel compositions, particularly topical compositions, comprising octadecadienoic acid and/or octadecenoi... | 05/25/2010 |
| 7637526 | Sliding coating for winter sports equipment According to the invention, a sliding coating for winter sports equipment which is a blend of a copolymer (I) and a copolymer (II) is provided, the copolymer (I) being a propylene copolymer which contains at least 50% of structural building blocks which originate fr... | 12/29/2009 |
| 7608633 | Heteroaryl-substituted acetone derivatives as inhibitors of phospholipase A The invention relates to novel heteroaryl substituted acetone derivatives which inhibit the enzyme phospholipase A2, pharmaceutical preparations containing these compounds and a method of producing these compounds. ... | 10/27/2009 |
| 7566333 | Electrosurgical device with floating-potential electrode and methods of using the same The present invention relates to electrosurgical probes suitable for tissue vaporization and cutting of tissue structures, more particularly for performing electrosurgical cutting, ablation (volumetric tissue vaporization), coagulating and/or modification within a b... | 07/28/2009 |
| 7563261 | Electrosurgical device with floating-potential electrodes An electrosurgical instrument, system and methods are provided for the vaporization, cutting, coagulation, or treatment of tissue in the presence of an electrically conductive fluid medium. The electrosurgical probe comprises at least one active electrode, and at le... | 07/21/2009 |
| 7495081 | Framework patched anti-CD20 antibody Framework (FR)-patching is a novel approach to modify immunoglobulin for reducing potential immunogenicity without significant alterations in specificity and affinity. Unlike previous described methods of humanization, which graft CDRs from a donor onto the framewor... | 02/24/2009 |
| 7491514 | Reducing the immunogenicity of anti-CD20 antibodies by framework patching Framework (FR)-patching is a novel approach to modify immunoglobulin for reducing potential immunogenicity without significant alterations in specificity and affinity. Unlike previous described methods of humanization, which graft CDRs from a donor onto the framewor... | 02/17/2009 |
| 7442544 | Recombinant sendai virus A method for regenerating Sendai virus particles by transfecting the Sendai virus genome to a host expressing all genes for the initial viral replication has been developed, enabling the genetic manipulation of Sendai virus and effective utilization of said virus as... | 10/28/2008 |
| 7338659 | Reducing immunogenicities of immunoglobulins by framework-patching Framework (FR)-patching is a novel approach to modify immunoglobulin for reducing potential immunogenicity without significant alterations in specificity and affinity. Unlike previous described methods of humanization, which graft CDRs from a donor onto the framewor... | 03/04/2008 |
| 7321026 | Framework-patched immunoglobulins Framework (FR)-patching is a novel approach to modify immunoglobulin for reducing potential immunogenicity without significant alterations in specificity and affinity. Unlike previous described methods of humanization, which graft CDRs from a donor onto the framewor... | 01/22/2008 |
| 7118871 | Reagents for monitoring nucleic acid amplification and methods of using same Described herein are novel indicator molecules of general formula (1): wherein Q, F, N, Nuc, X1 and X2 are as defined herein, including their tautomeric forms and their additive salts. The p... | 10/10/2006 |
| 7101685 | Recombinant Sendai virus A method for generating Sendai virus particles by transfecting the Sendai virus genome to a host expressing all genes for the initial viral replication has been developed, enabling the genetic manipulation of Sendai virus and effective utilization of said virus as t... | 09/05/2006 |
| 7004918 | Low cost orthosis for toe injuries A low-cost orthosis for the treatment of toe injuries is disclosed. The orthosis is a bilateral, monolithic structure molded from polymeric foam material and having an upper portion adapted to surround the heel, dorsal portions, and toes of a foot, and a lower porti... | 02/28/2006 |
| 6971995 | Method for splinting rib injuries A method for splinting rib injuries is disclosed. A pair of anchor strips having a plurality of fasteners on their exposed surfaces are attached to the skin of the chest cavity by an adhesive, the strips being more or less vertically oriented and equidistantly space... | 12/06/2005 |
| 6955660 | Internal expansion syringe adaptor An adaptor for connecting a syringe to an aspiration and/or irrigation device, typically a medical device such as a catheter, cannula or needle, is described herein. The adaptor is comprised of two components: a deformable elastomeric expansion sleeve and a relative... | 10/18/2005 |
| 6723532 | Negative strand RNA viral vector having autonomous replication capability A method for reconstituting Sendai viral particles by transfecting Sendai virus to a host expressing all genes for the initial replication has been developed, enabling the Production of negative strand RNA vectors highly useful for practical applications. ... | 04/20/2004 |
| 6645760 | Negative strand RNA viral vector having autonomous replication capability A method for reconstituting Sendai viral particles by transfecting Sendai virus to a host expressing all genes for the initial replication has been developed, enabling the production of negative strand RNA vectors highly useful for practical applications.... | 11/11/2003 |
| 6562864 | Catechin multimers as therapeutic drug delivery agents Described herein are catechin multimers, and particularly substituted catechin multimers, and their use as carrier moieties for the delivery of nucleophilic and cationic bioactive therapeutic agents to target sites in vivo. For example, substituted catech... | 05/13/2003 |
| 6557492 | System for transporting and storing live fish, components thereof and methods based thereon A live fish transport system is described herein. In particular, a modular live fish transport tote, an oxygen delivery system, an automated water treatment and delivery apparatus, and a chemically and biologically balanced aquaculture solution are descri... | 05/06/2003 |
| 6423742 | Compositions for reducing vascular plaque formation and methods of using same Described herein are novel, therapeutic pharmaceutical and nutraceutical compositions useful for treating stenotic vascular diseases and disorders, such as atherosclerosis and coronary artery disease, and reducing formation of plaque on vascular walls and... | 07/23/2002 |