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| Number | Title | Issue Date |
| 7632665 | Coupled cofactor-dependent enzymatic reaction systems in aqueous media The present application relates to a reaction system in which chemically valuable compounds can be obtained in high enantiomer concentrations with the aid of a coupled enzymatically operating transformation process. The coupled enzymatic reaction system comprises a ... | 12/15/2009 |
| 7588697 | Coated sodium percarbonate granules with improved storage stability The invention concerns coated sodium percarbonate granules comprising a core produced by fluidized bed spray granulation, containing sodium percarbonate as its main component, an inner coating layer containing an organic, hydrate-forming salt as its main component, ... | 09/15/2009 |
| 7553645 | Process for preparing L-amino acids using improved strains of the Enterobacteriaceae family The invention relates to a process for preparing L-amino acids by fermenting recombinant microorganisms of the Enterobacteriaceae family in which the ytfQ-ORF is overexpressed. ... | 06/30/2009 |
| 7534442 | Immunogenic compositions comprising covalently bound polysaccharides, antigen, and bacterial toxoid The present invention is directed to immunogenic conjugates comprised of a polymer, preferably a polysaccharide, with a covalently attached antigen and an agent for boosting a patient's immune response. The conjugates may be used in vaccines for a wide range of dise... | 05/19/2009 |
| 7531652 | Process for preparation of solid tris (2,3-dibromopropyl) isocyanurate The present invention is directed to a process for the isolation of tris(2,3-dibromopropyl)isocyanurate. The process uses an adsorbent which promotes easy conversion into a solid form of TDPI. The invention also includes to the solid TDPI product prepared in this wa... | 05/12/2009 |
| 7524657 | Alleles of the sigA gene from coryneform bacteria The invention relates to alleles of the sigA gene from coryneform bacteria which code for sigma factors A and a process for the fermentative preparation of L-lysine using bacteria which contain these alleles. ... | 04/28/2009 |
| 7518009 | Process for preparing mercaptoorganyl (alkoxysilanes) The present invention relates to a process for preparing mercaptoorganyl(alkoxysilanes), by hydrogenating bis(alkoxy-silylorganyl) polysulphides with hydrogen in the presence of at least one alcohol and a doped metal catalyst. The doped metal catalyst comprises at l... | 04/14/2009 |
| 7504542 | Preparation of α-hydroxy ketones via carbene-catalyzed umpolung reaction of aldehydes The present invention relates to the preparation of α-hydroxy ketones of the general formula I. In particular, the invention relates to novel imidazolinium carboxylate adducts and to a novel process for using catalytic amounts of imidazolium and imidazolinium carbo... | 03/17/2009 |
| 7491521 | Rhodococcus nitrile hydratase The invention relates to a Rhodococcus polynucleotide cluster which contains nucleotide sequences which encode polypeptides having the activity of a nitrile hydratase, of an auxiliary protein P15K which activates this enzyme and of a cobalt transporter... | 02/17/2009 |
| 7488481 | Polypeptides derived from anti-HIV-1 gp120 antibodies that abrogate gp120 binding to CCR5 The present invention is directed to peptides that are capable of blocking the entry of HIV-1 into host cells by means of the CCR5 receptor. The affinity of the peptides for gp120 on the HIV viral surface may be increased by sulfating tyrosine residues. In addition,... | 02/10/2009 |
| 7462221 | Process and device for the extraction of substances from silane-modified fillers Process for the extraction of substances from at least one silane-modified oxidic or silicatic filler, wherein at least one gas compressed by means of pressure and/or temperature is employed as the extraction agent and the compressed gas is led in the radial directi... | 12/09/2008 |
| 7435714 | Liquid detergent and cleaning agent composition comprising a multi-coated bleach particle The invention relates to liquid detergent and cleaning agent compositions of high storage stability. They comprise a liquid medium with a water content of up to 15 wt. % and particulate coating bleaching agents suspended therein. The bleaching agent has a dissolving... | 10/14/2008 |
| 7429567 | Sustained delivery of PDGF using self-assembling peptide nanofibers The present invention is directed to a therapeutic composition in which human PDGF is bound directly to peptides that self assemble into a biologically compatible gel. When implanted in a patient's body, the composition provides for the slow, sustained release of PD... | 09/30/2008 |
| 7402432 | Process for producing T lymphocytes The present invention is directed to an in vitro method for producing T lymphocytes. The method involves culturing bone marrow cells on a matrix seeded with keratinocytes and fibroblasts. ... | 07/22/2008 |
| 7399831 | Targeted delivery of biological factors using self-assembling peptide nanofibers The present invention is directed to methodology that allows a variety of compounds to be attached to self-assembling peptides using biotin/streptavidin linkages. The peptides can be used to form a biologically compatible membrane that promotes the growth and differ... | 07/15/2008 |
| 7386349 | Rapid analgesia for skin puncture The present invention is directed to a device for providing transcutaneous electrical stimulation (TENS) to the finger of a patient at the same time that the finger is being punctured for the purpose of obtaining a blood sample. The device should reduce the pain ass... | 06/10/2008 |
| 7384997 | Rubber mixtures The invention is directed to rubber mixtures comprising rubber, fillers, optionally further rubber auxiliaries and at least one organosilane of the general formula I: R1R2R3SiR4—SH (I) wherein: | 06/10/2008 |
| 7368600 | Method for production of methionine from homoserine The invention relates to a method for production of D- and/or L-methionine via D- and/or L-homoserine with subsequent chemical transformation to give methionine. ... | 05/06/2008 |
| 7364718 | Process for the production of hydrogen peroxide Hydrogen peroxide is produced by reacting hydrogen and oxygen in the presence of a noble metal catalyst in a liquid reaction medium, the reaction being performed in the presence of a sulfuric acid alkyl ester. In the presence of sulfuric acid alkyl esters the noble ... | 04/29/2008 |
| 7332183 | Multilayer dosage forms containing NSAIDs and triptans The present invention is directed to multilayer pharmaceutical tablets in which an NSAID and a triptan are present in separate and distinct layers. The layers are in a side-by-side configuration, which allows the dissolution of triptan and NSAID to occur independent... | 02/19/2008 |
| 7326393 | Process for the conversion of polysulfanes The invention provides a process for the removal of polysulfanes from gas streams formed during H2S synthesis. ... | 02/05/2008 |
| 7319026 | Amino acid-producing bacteria and a process for preparing L-amino acids The invention relates to amino acid-producing bacteria from the family Enterobacteriaceae, in particular from the species Escherichia coli, which contain a stop codon chosen from the group amber, ochre and opal in the nucleotide sequence for the coding region... | 01/15/2008 |
| 7306932 | Coryneform bacteria with altered glucokinase activity in the production of L-lysine The invention relates to alleles of the glk gene from coryneform bacteria coding for glucokinases, and to processes for the production of L-lysine by fermentation using bacteria containing such alleles. ... | 12/11/2007 |
| 7288383 | Eosinophil-derived neurotoxin as a marker for ovarian cancer The present invention is directed to methods of identifying women at increased risk of having ovarian cancer. Identification is based upon the extent to which biological samples derived from the women exhibit elevated levels of eosinophil-derived neurotoxin (EDN). | 10/30/2007 |
| 7288402 | Rhodococcus nitrile hydratase The invention relates to a Rhodococcus polynucleotide cluster which contains nucleotide sequences which encode polypeptides having the activity of a nitrile hydratase, of an auxiliary protein P15K which activates this enzyme and of a cobalt transporter, to tr... | 10/30/2007 |
| 7271313 | Presenilin-deficient mouse model of age-dependent neurodegeneration and cognitive loss The present invention is directed to recombinantly engineered mice that are deficient in the expression of both presenilin-1 and presenilin-2. The mice exhibit characteristics of age-dependent cognitive impairments and neurodegeneration similar to those seen in Alzh... | 09/18/2007 |
| 7255735 | Surface-modified silicon dioxide-titanium dioxide mixed oxides Pyrogenically prepared surface-modified silicon dioxide-titanium dioxide mixed oxides are prepared by spraying pyrogenically prepared silicon dioxide-titanium dioxide mixed oxides with a surface-modifying agent. The surface-modified pyrogenically prepared silicon di... | 08/14/2007 |
| 7256021 | Enterobacteriaceae strains with an attenuated aspA gene for the fermentative production of amino acids The invention relates to a process for the preparation of L-amino acids, especially L-lysine, L-valine, L-homoserine and L-threonine, by fermenting a microorganism of the genus Escherichia which has a mutation or deletion in the gene encoding aspartate ammoni... | 08/14/2007 |
| 7247465 | Screening process for hydantoin racemases The present invention relates to a screening process for hydantoin racemases and to novel hydantoin racemases, to the nucleic acid sequences coding therefor and to a proces for mutagenesis. Hydantoin racemases are of interest in connection with the production... | 07/24/2007 |
| 7241908 | Process for the direct synthesis of hydrogen peroxide The invention is directed to the preparation of organic or aqueous-organic hydrogen peroxide solutions by direct synthesis from a non-explosive gaseous mixture containing hydrogen and oxygen. The process is carried out in the presence of a noble metal catalyst, usin... | 07/10/2007 |
| 7238335 | Process for the preparation of hydrogen peroxide by the anthraquinone cyclic process The invention concerns a process for the preparation of hydrogen peroxide by the anthraquinone cyclic process. The process includes a regeneration stage in which working solution is regenerated by being brought into contact with an aqueous solution containing an alk... | 07/03/2007 |
| 7229958 | Fragrance alcohol-releasing polysiloxane Organopolysiloxanes which contain a fragrance alcohol Y—OH bonded via a betaine ester group having the structure —N+R1R2—CH2—C(O)OY, cleave off the fragrance alcohol under acid conditions and are resistant to hydro... | 06/12/2007 |
| 7217544 | Method for the preparation of L-amino acids from D-amino acids The invention relates to recombinant microorganisms which, in comparison to the starting organism, have a higher concentration or activity of a D-amino acid oxidase, of an L-amino acid dehydrogenase, of an NADH cosubstrate regenerating enzyme and, if necessary, of a... | 05/15/2007 |
| 7214526 | Alleles of the mqo gene from coryneform bacteria The invention relates to mutants and alleles of the coryneform bacterium mqo gene which encodes malate quinone oxidoreductases which contain any amino acid apart from L-serine at position 111, or a comparable position, in the amino acid sequence, and to processes fo... | 05/08/2007 |
| 7211415 | Enterobacteriaceae strains over-expressing the yfiD gene for the fermentative production of L-amino acids The present invention relates to a process for the production of L-amino acids by fermentation of recombinant microorganisms of the Enterobacteriaceae family, wherein a) the yfiD ORF and/or the pflB gene or nucleotide sequences coding for the gene produ... | 05/01/2007 |
| 7201163 | Method for altering the body temperature of a patient using a nebulized mist Methods for changing the body temperature of a patient by having them breathe a mist created by nebulizer. The temperature of the mist is adjusted using a heat exchanger. The methods may be used to either cool or warm patients for a variety of clinical reasons. In a... | 04/10/2007 |
| 7195748 | Process for the production of hydrogen peroxide The invention relates to a process for the production of hydrogen peroxide by the anthraquinone process, comprising a hydrogenation stage, an oxidation stage and an extraction stage. According to the invention, catalytic hydrogenation of anthraquinone derivatives di... | 03/27/2007 |
| 7172652 | Carbon black granules The present invention is directed to carbon black granules containing a sorbitan triester. In addition, a process for the production of these carbon black granules is described, in which a powdered carbon black or beaded carbon black is beaded with a sorbitan triest... | 02/06/2007 |
| 7148176 | Production of novel phosphane ligands and use in catalytical reactions The present invention is directed to phosphine ligands and the use of such ligands in catalytic complexes with transition metals. The catalysts may be used in a variety of reactions and are especially useful for refining halogenoaromatics. ... | 12/12/2006 |
| 7119228 | Process for producing methionine The present invention is directed to an improved process for producing methionine in which the by-product methionyl-methionine is quickly converted to the product methionine by a hydrolysis reaction. The process is performed at high temperatures (200° C. to 280° C... | 10/10/2006 |
