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| Number | Title | Issue Date |
| 5468773 | Methods for inhibiting bone loss and cartilage degradation using wortmannin and its analogs Wortmannin and certain of its analogs are inhibitors of bone loss/bone resorption and cartilage degradation.... | 11/21/1995 |
| 5466810 | 2-amino-3-aroyl-benzo[ଲ]thiophenes and methods for preparing and using same to produce 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-(2-aminoethoxy)-benzoyl]benzo[ଲ] thiophenes A group of 2-amino-3-aroyl-benzo[ଲ]thiophenes are prepared by treating an aldehyde with an anion of dimethylamino thioformamide, cyclizing the -hydroxy thioamide, and subsequently acylating the benzo[ଲ]thiophene to yield the 2-amino-3-a... | 11/14/1995 |
| 5462949 | Methods of inhibiting fertility in women A method of inhibiting fertility in women comprising administering to a female human an effective amount of a compound having the formula ##STR1## and pharmaceutically acceptable salts and solvates thereof.... | 10/31/1995 |
| 5462937 | Methods for inhibiting vascular smooth muscle cell proliferation and restinosis Methods of inhibiting vascular smooth muscle cell proliferation and restinosis are disclosed comprising administering to a human or other mammal in need of treatment an effective amount of a compound having the formula ##STR1## wherein R1 | 10/31/1995 |
| 5461065 | Methods for inhibiting endometriosis A method of inhibiting endometriosis comprising administering to a human in need of treatment an effective amount of a compound having the formula ##STR1## Wherein R1 and R3 are independently hydrogen, --CH3, ##STR2##... | 10/24/1995 |
| 5461064 | Methods of inhibiting atrophy of the skin and vagina A method of inhibiting atrophy of the skin or vagina comprising administering to a human in need thereof an effective amount of a compound having the formula ##STR1## wherein R1 and R3 are independently hydrogen, ##STR2## ... | 10/24/1995 |
| 5457117 | Method for inhibiting bone loss using 6-hydroxy-2-(4-hydroxyphenyl)-benzo[B][2-(piperidin-1-yl)ethoxyphenylime thanone hydrochloride The current invention provides a method useful for inhibiting the loss of bone using 6-hydroxy-2-(4-hydroxyphenyl)-benzo(B)thien-3-yl-4[2-(piperidin-1-ethoxyph enol]methanone hydrochloride.... | 10/10/1995 |
| 5457116 | Methods of inhibiting uterine fibrosis A method of inhibiting uterine fibrosis comprising administering to a human or other mammal in need of treatment an effective amount of a compound having the formula ##STR1## Wherein R1 and R3 are independently hydrogen, ##... | 10/10/1995 |
| 5457113 | Methods for inhibiting vascular smooth muscle cell proliferation and restinosis Methods of inhibiting vascular smooth muscle cell proliferation and vascular restinosis comprising administering to a human or other mammal in need of treatment an effective amount of a compound having the formula ##STR1## wherein R1 and R... | 10/10/1995 |
| 5451590 | Methods of inhibiting sexual precocity A method of inhibiting sexual precocity comprising administering to a human in need thereof an effective amount of a compound having the formula ##STR1## wherein R1 and R3 are independently hydrogen, --CH3, ##STR2## ... | 09/19/1995 |
| 5451589 | Methods of inhibiting ovarian dysgenesis, delayed puberty, or sexual infantilism A method of inhibiting ovarian dysgenesis, delayed puberty, or sexual infantilism comprising administering to a human in need thereof an effective amount of a compound having the formula ##STR1## wherein R1 and R3 are independen... | 09/19/1995 |
| 5447941 | Methods of inhibiting pulmonary hypertensive diseases with raloxifene and related benzothiophenes A method of inhibiting pulmonary hypertensive disease comprising administering to a human in need thereof an effective amount of a compound having the formula ##STR1## wherein R1 and R3 are independently hydrogen, --CH3 | 09/05/1995 |
| 5446061 | Methods for lowering serum cholesterol A method of lowering serum cholesterol levels, comprising administering an effective amount of a compound having the formula ##STR1## wherein: R1 and R2 are, independently, --H, --OH, halo, --OC1 -C17 alkyl... | 08/29/1995 |
| 5446053 | Methods of inhibiting dysfunctional uterine bleeding A method of inhibiting dysfunctional uterine bleeding comprising administering to a human in need thereof an effective amount of a compound having the formula ##STR1## wherein R1 and R3 are independently hydrogen, ##STR2## ... | 08/29/1995 |
| 5441966 | Methods of inhibiting Turner's syndrome A method of inhibiting Turner's Syndrome comprising administering to a human in need thereof an effective amount of a compound having the formula ##STR1## wherein R1 and R3 are independently hydrogen, --CH3, ##STR2## ... | 08/15/1995 |
| 5441965 | Methods of inhibiting thrombin A method of inhibiting thrombin and its attending diseases and conditions comprising administering to a human in need of treatment an effective amount of a compound having the formula ##STR1## wherein R1 and R3 are independently... | 08/15/1995 |
| 5441964 | Methods for inhibiting bone loss using substituted benzothiophene A method of inhibiting bone loss comprising administering to a human in need of treatment an effective amount of a substituted benzothiophene.... | 08/15/1995 |
| 5439923 | Method of inhibiting seborrhea and acne A method of inhibiting acne or seborrhea comprising administering to a human in need of treatment an effective amount of a compound having the formula ##STR1## wherein R1 and R3 are independently hydrogen, --CH3, ... | 08/08/1995 |
| 5420349 | 2-amino-3-aroyl-benzo[ଲ]thiophenes and methods for preparing and using same to produce 6-hydroxy-2-(4-hydroxyphenyl)-3-]benzo[4-(2-aminoethoxy)-benzoyl[ଲ] thiophenes A group of 2-amino-3-aroyl-benzo[ଲ]thiophenes are prepared by preparing an -hydroxy thioacetamide by silyl mediated condensation of an aldehyde with an anion of dialkylamino thioformamide, cyclizing the -hydroxy thioamide, and subseque... | 05/30/1995 |
| 5418252 | Method for inhibiting cartilage degradation A method of inhibiting cartilage degradation comprising administering to a human or other mammal in need of treatment an effective amount of a compound having the formula ##STR1## wherein R1 and R3 are independently hydrogen, ... | 05/23/1995 |
| 5407947 | Methods for inhibiting bone loss using pyrolidine and piperidine substituted benzopyrans A method of inhibiting bone loss comprising administering to an animal an effective amount of a compound having the formula ##STR1## wherein: R1 and R2 are, independently, --H, --OH, halo, --OC1 -C17 alkyl,... | 04/18/1995 |
| 5391557 | Methods for the treatment of peri-menopausal syndrome A method of treating peri-menopasual syndrome comprising administering to a human in need of treatment an effective amount of a compound having the formula ##STR1## wherein R1 and R3 are independently hydrogen, --CH3,... | 02/21/1995 |
