...that the Slinky toy was the result of a failed attempt by engineer Richard James to produce an antivibration device for ship instruments? His goal was to develop a spring that would instantaneously counterbalance the wave motion that rocks a ship at sea. Instead, he developed the Slinky.
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| Number | Title | Issue Date |
| 7838216 | Human gene related to but distinct from EGF receptor gene The isolation, cloning and characterization of a human gene related to but distinct from EGF receptor gene has been described. Nucleotide sequence of the gene and amino acid sequence of the polypeptide encoded by the gene have been determined. The use of the nucleic... | 11/23/2010 |
| 5869277 | Method for measuring type IV collagenase The present invention relates to the development of a modified substrate capture immunoassay useful in the detection of a neutral metalloproteinase enzyme, type IV collagenase. Capture and immobilization of this enzyme can be achieved by coating the micro... | 02/09/1999 |
| 5811262 | Hepatocellular carcinoma oncogene The present invention relates to an oncoprotein specific for hepatocellular carcinomas and to a nucleotide sequence that codes for such a protein. The invention further relates to screening and diagnostic methodologies (and kits based thereon) that make u... | 09/22/1998 |
| 5792657 | Steroid secreting human adrenocortical carcinoma cell lines Continuous cell lines have been established from adrenocortical corcinomas. The cell lines are maintained in fully defined serum-free, steroid-free mediums. The cells of the invention, as exemplified by NCI-H295 cells, express all of the major pathways of... | 08/11/1998 |
| 5693778 | Arg a human gene related to but distinct from abl proto-oncogene The invention concerns the isolation and sequencing of a new gene, arg, related to the abl proto-oncogene. The gene gets transcripted to two mRNA's; which in turn form two proteins. Antibodies, oligonucleotide probes and assays of detecting the arg gene, ... | 12/02/1997 |
| 5403926 | Hepatocellular carcinoma oncogene The present invention relates to an oncoprotein specific for hepatocellular carcinomas and to a nucleotide sequence that codes for such a protein. The invention further relates to screening and diagnostic methodologies (and kits based thereon) that make u... | 04/04/1995 |
| 5380830 | Molecular clones of bovine immunodeficiency-like virus Biologically active proviral molecular clones of bovine immunodeficiency-like virus and cell lines infected with the same have been prepared. Various utilities of the clones are described.... | 01/10/1995 |
| 5321014 | Molecular encapsulation and delivery of alkenes alkynes and long chain alkanes, to living mammalian cells A complex of a cyclodextrin and an alkane, alkene, alkyne, aromatic compound, etc. can be prepared according to the method of the present invention. These complexes can be delivered to prokaryotic and eukaryotic cells, tissues, and organs in vitro and in ... | 06/14/1994 |
| 5256534 | CD4+, latently HIV-1-infected hematopoietic progenitor cells The present invention relates to a unique physiologic model of chronic human immunodeficiency virus type-1 (HIV-1) infection. In particular, the present invention relates to a chronically infected promyelocyte cell line harboring a single integrated provi... | 10/26/1993 |
| 5219991 | Macrophage stimulating protein The present invention relates to a method of purifying macrophage stimulating protein (MSP) and to the highly purified MSP. The present invention further relates to antibodies to MSP. The highly purified MSP may be used for fighting pathogen infections.... | 06/15/1993 |
| 5183756 | Monoclonal antibody (D612) having selective reactivity for gastrointestinal caricinomas and method for employing the same The present invention relates to the monoclonal antibody (termed D612) having selective reactivity for gastrointestinal carcinoma and methods for employing the same. A hybridoma producing such antibodies has been prepared.... | 02/02/1993 |