U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Icon_funbox Bizarre Patents

Patent No. 5356330

Apparatus for Simulating a High Five

A self-righting hand-arm configuration which is adapted to pivot when struck by a user, thereby simulating a "high five."

Newsletter  PatentStorm News

Make the Most of Our Site

See this month's Top Inventors and Most Cited Patents.

Stay on top of the latest innovations by subscribing to an RSS feed.

Registered users: Manage your profile.

 

Attorney: Rowland; Bertram I.


Number of patents: 373
Last date: August 14, 2007

1                    
NumberTitleIssue Date
7256011Enzyme activation protease assay
A protein reagent is provided for measuring protease enzyme activity in a sample. The protein reagent comprises two inhibition entities joined by a linker comprised of an indicator enzyme donor and an amino acid sequence susceptible to enzymatic cleavage. The protei...
08/14/2007
6333031Receptor derived peptides as modulators of receptor activity
Oligopeptides having an amino acid sequence corresponding to a receptor's extracellular domain, and having sequence similarity to regulatory peptides from MHC class I antigens, enhance or replace the physiological response of ligand binding to the corresp...
12/25/2001
6277606Representational approach to DNA analysis
Methodology is provided for developing probes for identifying sequence differences between two related DNA populations, sets of DNA fragments or collections of restriction-endonuclease-cleaved DNA or cDNA. The method employs an initial stage to obtain a r...
08/21/2001
6184249Androgen receptor suppressors in the therapy and diagnosis of prostate cancer, alopecia and other hyper-androgenic syndromes
Substituted phenylalanines are provided comprising an hydantoin, urea or 2-hydroxyl, 2-methylpropionyl group, dimers thereof and alkyl, polyfluoroamido and haloarylamino derivatives thereof, as well as radiolabeled derivatives thereof. The compounds bind ...
02/06/2001
6123928Sunblocking polymers and their novel formulations
Novel polymeric biologically inert compositions and their intermediates, as well as sunscreen formulations comprising them and making them invisible, are provided for broad range protection from ultraviolet radiation. Acryl polymers comprising at least tw...
09/26/2000
6117872Enhancement of exercise performance by augmenting endogenous nitric oxide production or activity
NO precursors are administered at elevated levels in addition to the diet of the individual to enhance exercise performance. Particularly, L-arginine and L-lysine by enhancing endothelial NO production can provide for greater aerobic capacity and improved...
09/12/2000
6103537Capillary assays involving separation of free and bound species
The present invention concerns methods for masking inhomogeneity of a member of a specific binding pair (sbp) employed in a capillary electroseparation. The method comprises binding the sbp member to synthetic particles that become localized during capill...
08/15/2000
6103199Capillary electroflow apparatus and method
The present invention concerns an apparatus for conducting a microfluidic process. The apparatus comprises integral first and second plates. The first plate comprises an array of sample receiving elements for receiving a plurality of samples from an array...
08/15/2000
6093296Method and device for moving molecules by the application of a plurality of electrical fields
Devices and methods are disclosed for moving charged molecules through a medium by the application of a plurality of electrical fields of sufficient strength and applied for sufficient amounts of time so as to move the charged molecules through the medium...
07/25/2000
6074827Microfluidic method for nucleic acid purification and processing
Integrated microfluidic devices comprising at least an enrichment channel and a main electrophoretic flowpath are provided. In the subject integrated devices, the enrichment channel and the main electrophoretic flowpath are positioned so that waste fluid ...
06/13/2000
6072069Biodegradable nonionic contrast media
Novel non-ionic contrast media are provided, which fulfill the requirements for x-ray visualization media, while being biodegradable. The compounds are characterized by being triiodo-3,5-diaminobenzoic acid derivatives, where the functional groups are der...
06/06/2000
6063432Arginine or lysine containing fruit healthbar formulation
Health bars are provided having high dosages of at least one of the amino acids L-arginine and L-lysine in conjunction with fruit solids and paste, protein and carbohydrates. A number of different fruit sources may be used, grapes finding particular use, ...
05/16/2000
6056860Surface modified electrophoretic chambers
Electrophoretic chambers having at least a region of surface modification, and methods for their fabrication, are provided. In some embodiments the subject chambers include in the region of surface modification an anchoring polymeric layer interpenetratin...
05/02/2000
6054034Acrylic microchannels and their use in electrophoretic applications
Microchannels having at least an acrylic inner surface and methods of their use in electrophoretic applications are provided. The subject microchannels may be in the form of a variety of configurations suitable for holding an electrophoretic medium. The s...
04/25/2000
5945452Treatment of vascular degenerative diseases by modulation of endogenous nitric oxide production or activity
Atherogenesis and restenosis are treated by long term administration of physiologically acceptable compounds which enhance the level of endogenous nitric oxide or other intermediates in the NO induced relaxation pathway in the host. Alternatively, or in c...
08/31/1999
5922617Rapid screening assay methods and devices
Methods and apparatus are employed for determining interactions between different components, of the same or different type of composition. The apparatus provides for arrays of samples in tracks, where light emitting labels are excited and emitted light d...
07/13/1999
5922551Agglutrimetric platelet binding assays in blood
Methodology which avoids the problems associated with interference from whole blood is provided for instrumented determination of platelet binding function. Particularly, small particles to which fibrinogen is bound, and which contain an infrared light ab...
07/13/1999
5891459Enhancement of vascular function by modulation of endogenous nitric oxide production or activity
Vascular function and structure is maintained or improved by long term administration of physiologically acceptable compounds, namely L-arginine, L-lysine, physiologically acceptable salts thereof, and polypeptide precursors thereof, which enhance the lev...
04/06/1999
5882884Expression of proteinaceous sweeteners in yeast
A yeast expression system is provided for expressing novel protein sweeteners. The construct provides for secretion of the protein sweeters into a form which can be readily purified and isolated, providing an active product....
03/16/1999
5852058Intramural delivery of nitric oxide enhancer for inhibiting lesion formation after vascular injury
Vessels suffering vascular injury from angioplasty are treated with L-arginine intramurally. The incidents associated with restenosis are substantially reduced providing for a reduced incidence of restenosis as a result of the injury....
12/22/1998
5830686Tissue-specific enhancer active in prostate
The invention provides a human prostate-specific transcriptional regulatory sequence, polynucleotides comprising such regulatory regions, toxin gene constructs wherein a toxin gene is expressed under the transcriptional control of a human prostate-specifi...
11/03/1998
5817770Cocaethylene immunogens and antibodies
The ethyl ester of derivatives of benzoyl ecgonine are provided having a linking group at the para position of the benzoyl group. The derivatives are used to bond to immunogenic polypeptides for production of antisera and monoclonal antibodies. The antise...
10/06/1998
5813406Strain-sensing goniometers, systems and recognition algorithms
Goniometers are provided having internal compensation employing two opposing variable resistance strain sensing elements separated by a flexible film. The goniometers may be used in sets for detecting complex hinge or joint movements, where patterns of hi...
09/29/1998
5723588Protein-enriched thermoplastics
Thermoplastics interdispersed with a variety of functional thermostable polypeptides, including proteins, and methods of making such thermoplastics are provided. The disclosure demonstrates that certain polypeptides can retain functional activity through ...
03/03/1998
5705626Cloned glutamic acid decarboxylase nucleic acids
The invention is directed to isolated polypeptides useful in ameliorating autoimmune disease....
01/06/1998
5654419Fluorescent labels and their use in separations
Compositions are provided comprising sets of fluorescent labels carrying pairs of donor and acceptor dye molecules, designed for efficient excitation of the donors at a single wavelength and emission from the acceptor in each of the pairs at different wav...
08/05/1997
5632984Method of treatment of macular degeneration
Intraocular administration of drugs such as ଱-2a interferon is employed in the treatment of age-related macular degeneration. Intraocular administration obviates the side effects associated with systemic administration, concentrates the drug at the ...
05/27/1997
5612034Super-globuling for in vivo extended lifetimes
First and second compounds are provided, where the first compound is administered to a mammalian host into blood for covalent bonding to blood components, where the components have an extended lifetime in the blood stream. The first compound comprises an ...
03/18/1997
5607974Treatment of diseases associated with cysteine deficiency
Patients suffering from a pathological condition resulting in reduced intracellular cysteine levels are treated with a cysteine source capable of being transported to the cellular cytoplasm. Particularly, N-acetyl cysteine is employed in the treatment of ...
03/04/1997
5607842Use of tRNA genes to stabilize the inheritance of unstable plasmids in populations of growing cells
Expression systems are provided, where plasmids can be safely maintained in a prokaryotic host, by providing for a tRNA gene for an essential tRNA in a tRNA gene negative background. A non-selective medium can be employed to permit vigorous growth of the ...
03/04/1997
5605810NADH oxidase assay for neoplasia determination
NADH oxidase is shown to be a target for a variety of uses in diagnosis and therapy. Particularly, the NADH oxidase associated with neoplastic cells is immunologically and biologically different from NADH oxidase associated with normal cells. Thus, the pr...
02/25/1997
5606019Synthetic protein as implantables
Copolymers are provided having varying ratios of elastin and fibroin repeating units. By varying the length of segments of the elastin and fibroin repeating units, the absorption can be greatly varied. Tensile strengths remain relatively constant regardle...
02/25/1997
5589180Method for treating nerve injury pain associated with shingles (herpes-zoster and post-herpetic neuralgia) by topical application of lidocaine
Methods and compositions are offered for reducing nerve injury pain associated with shingles (herpes-zoster and post-herpetic neuralgia), where intradermal delivery of lidocaine is maintained for a predetermined period of time. The lidocaine appears to sp...
12/31/1996
5573781Methods and compositions for the treatment of a host with a cellular proliferative disease
Methods and compositions are provided for the treatment of a host with a cellular proliferative disease, particularly a neoplasia. In the subject methods, a pharmaceutically acceptable, substantially anhydrous, injectable semi-solid composition which acts...
11/12/1996
5569753Cancer detection probes
Nucleic acid sequence probes are provided for the detection of lesions associated with neoplastic cells. The sequences can be used for identifying the locus associated with the lesion, for determining cancer susceptibility of cells, as well as categorizin...
10/29/1996
5569673Capsacinoid compounds as proliferation inhibitors
N-Acylated catecholmethylamines are used to inhibit cancer cell proliferation. Specifically, capsaicin is found to inhibit growth at low concentration, but not normal cells....
10/29/1996
5567627Method and composition for the simultaneous and discrete analysis of multiple analytes
A method for detecting multiple subpopulations of analytes of interest in a sample employing a complementary binding moiety to each of said analytes bound to a solid support, wherein each analyte and its complementary binding moiety comprise first and sec...
10/22/1996
5565554Dimeric fluorescent energy transfer dyes comprising asymmetric cyanine azole-indolenine chromophores
Novel fluorescent DNA-staining dyes are provided combining asymmetric cyanine azole-indolenine dyes, which provide for strong DNA affinity, large Stokes shifts and emission in the red region of the spectrum. The dyes find particular application in gel ele...
10/15/1996
5563035Estrogen receptor regulation and its uses
ERF-1 is shown to be a transcriptional regulator of the expression of the estrogen receptor, where elevated ERF-1 is related to elevated expression of the estrogen receptor. By monitoring the level of ERF-1, one can relate phenotypic characteristics of ca...
10/08/1996
5556780CDNAS encoding mouse and rat type-2 angiotensin II receptors and their expression in host cells
An angiotensin II type 2 receptor (AT2 receptor), structurally related cell receptors, nucleic acids encoding such AT2 receptors, AT2 receptor-related peptides, and methods of using AT2 receptors and AT2
09/17/1996
1                    
 
Sign InRegister
Username  
Password   
forgot password?