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| Number | Title | Issue Date |
| 8170466 | System and method for automated assessment of constrained constructed responses A system and method for automated assessment of constrained constructed responses provides for automatic, e.g., programmatic, assessing of a test subject response to a constrained constructed response item or question. In one embodiment, paper test materials with te... | 05/01/2012 |
| 8143068 | Oxidation resistant indicator molecules Compounds having enhanced oxidation stability are disclosed. The compounds have an aryl boronic acid residue having one or more electron withdrawing groups on the aromatic moiety which contains the boronic acid residue, such that the molecule has enhanced oxidation ... | 03/27/2012 |
| 8128414 | System and method for the development of instructional and testing materials Aspects of the present invention provide a system that supports (1) the development and administration of instructional materials and/or programs, (2) the development, administration, scoring, and reporting of assessment materials and/or programs, and/or (3) the int... | 03/06/2012 |
| 8030290 | Cell-type specific aptamer-siRNA delivery system for HIV-1 Therapy The present invention relates to compositions and methods for delivery of siRNA to specific cells or tissue. More particularly, the present invention relates to compositions and methods for cell type-specific delivery of anti-HIV siRNAs via fusion to an anti-gp120 a... | 10/04/2011 |
| 8029767 | Fluorescent membrane intercalating probes and methods for their use The invention relates to a family of cyanine dyes which fluoresce in the far red and near infra red wavelengths of the spectrum and preferably possess lipophilic side chains. The dyes of the invention are soluble in commercially available membrane staining vehicles,... | 10/04/2011 |
| 8012966 | Pyrrolo [3,2-c] pyridine-4-one 2-indolinone protein kinase inhibitors The present invention relates to pyrrolo[3,2-c]pyridine-4-one 2-indolinone compounds of Formula (I) and their pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8X, Y and have ... | 09/06/2011 |
| 7984080 | System and method for locating a selected number and displaying the number as it appears in a document containing the number The disclosure describes a system and method for locating a number in a source document by presenting and manipulating data on private and public companies. A central database of financial information is established. A target entity is entered within the central dat... | 07/19/2011 |
| 7977534 | Promotion of somatic embryogenesis in plants by gene expression The present invention relates to methods for promoting somatic embryogenesis from a tissue or organ of a plant, by overexpressing a Wuschel gene in said tissue or organ. In one embodiment, such overexpression can be used as a silent selectable marker for tran... | 07/12/2011 |
| 7964716 | Fluorescent primer system for detection of nucleic acids (Q priming) The present invention is directed to a self-quenching primer comprising; a fluorophore that can be quenched by guanine; an oligonucleotide sequence that forms a hairpin; an oligonucleotide that is a target specific sequence and; use in amplification reactions, parti... | 06/21/2011 |
| 7960573 | Method for enantioselective hydrogenation of chromenes A method for preparing an enantiomeric chromane, by asymmetrically hydrogenating a chromene compound in the presence of an Ir catalyst having a chiral ligand. The method includes the enantioselective preparation of enantiomeric equol. A preferred Ir catalyst has a c... | 06/14/2011 |
| 7960432 | Compositions and products containing S-equol, and methods for their making A composition for use in making commercial food and skin products comprising S-equol or mixtures, including both a non-racemic mixture and a racemic mixture, of S-equol and R-equol. The composition can be used to make articles of commerce such as food supplements, p... | 06/14/2011 |
| 7941904 | Method and apparatus for stripping a contact-limiting element from a pipette probe An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automat... | 05/17/2011 |
| 7399476 | Nucleic acid free ghost preparations The invention relates to preparations of bacterial ghosts which are substantially free of living bacterial cells and/or nucleic acids and their use in pharmaceutical preparations. ... | 07/15/2008 |
| 7345073 | Method for treating cryptorchidism The present invention relates to a method and pharmaceutical composition for the treatment of male individuals suffering from cryptorchidism comprising administering to said individuals an effective amount of an aromatase inhibitor, preferably finrozole. ... | 03/18/2008 |
| 7320862 | Microfluidic extraction method The invention relates to an extraction method for isolating target molecules from a sample using a microfluidic carrier. ... | 01/22/2008 |
| 7294472 | Method for identifying modulators of G protein coupled receptor signaling This invention relates to methods for identifying peptides and other compounds which block or enhance G protein coupled receptor mediated signaling with high affinity and specificity and/or which stabilize a particular conformer of a G protein coupled receptor. Assa... | 11/13/2007 |
| 7223548 | Method of screening a chemical for binding to a proline-rich nuclear receptor co-regulatory protein/nuclear receptor complex The invention relates to assays for screening for chemicals which affect the binding between proteins comprising an SH3 binding motif (such as Proline-rich Nuclear Receptor Co-regulatory protein (PNRC)) and nuclear receptor proteins. Compounds which affect the bindi... | 05/29/2007 |
| 7208279 | Method for identifying inhibitors of G protein coupled receptor signaling This invention relates to methods for identifying peptides and other compounds which block G protein coupled receptor mediated signaling with high affinity and specificity. Assays developed in conjunction with these methods also are disclosed. ... | 04/24/2007 |
| 7205452 | Control of bacterial infection by quenching quorum-sensing of plant pathogenic bacteria Transgenic plants having resistance against bacterial soft rot diseases, harboring the bacterial autoinducer inactivation gene encoding (AiiA) protein, and methods for protecting plants from bacterial pathogens by transforming the plants with the aiiA gene are discl... | 04/17/2007 |
| 7205007 | Peri-operative and peri-procedure nutritional supplementation The invention provides a nutritional supplement system and program for patients undergoing or who have undergone a surgical or other invasive or stressful procedure, or who have suffered an injury. This nutritional supplement for the peri-operative period is designe... | 04/17/2007 |
| 7195779 | Storage stable thyroxine active drug formulations and methods for their production This invention provides a storage-stable dosage form of a thyroxine active drug composition which exhibits an improved stability. The formulation contains a thyroxine active drug substance, an alditol, and a saccharide, and, optionally, additional pharmaceutically a... | 03/27/2007 |
| 7172999 | Method and preparations for stabilizing biological materials by drying methods without freezing The present invention concerns processes for the production of dry, partially amorphous products containing biologically active and in particular therapeutically active material which are macroscopically homogeneous substance mixtures, the substance mixtures being s... | 02/06/2007 |
| 7166585 | 24-Sulfur-substituted analogs of 1α,25-dihydroxy vitamin D The present invention provides novel C24-sulfone analogs of 1α,25-dihydroxy vitamin D3, compositions comprising these compounds and methods of using these compounds as selective inhibitors of CYP24. In particular, the compounds of the invention are usefu... | 01/23/2007 |
| 7163685 | Human cytomegalovirus antigens expressed in MVA and methods of use DNA and protein constructs useful in producing vaccines against human cytomegalovirus contain optionally N-end modified and N-terminal ubiquitinated human cytomegalovirus antigenic proteins, including pp65, pp150, IE1, gB and antigenic fragments thereof. Vaccine vir... | 01/16/2007 |
| 7147949 | Fuel electrode of solid polymer electrolyte fuel cell The present invention provides a fuel electrode of a solid polymer electrolyte fuel cell for advancing a fuel cell reaction to oxidize the fuel introduced through a diffusion layer, comprising at least one reaction layer which is in contact with a solid polymer elec... | 12/12/2006 |
| 7132526 | Isolation and characterisation of an anther-specific promoter (CoFS) in cotton The present invention relates to an anther-specific cotton gene (CoFS), and active promoter fragments thereof. These promoters show strong anther-specific activity. ... | 11/07/2006 |
| 7132482 | Method for vulcanizing caoutchouc or latex by applying a mixture of sulfur and a complexing agent The invention relates to a method for vulcanizing caoutchouc or latex by adding a mixture M which contains a component a) from a1) 20 to 96% by weight of sulfur, a2) 4 to 80% by weight of a complexing agent, and optionally other additives b) to caoutchouc or latex a... | 11/07/2006 |
| 7122348 | AAV2 Rep protein fusions This invention pertains to methods for promoting stable and site-specific integration of rep deleted recombinant adeno-associated virus vectors which result in less variable transgene expression and increased safety. These vectors are useful for delivery of a functi... | 10/17/2006 |
| 7101865 | 24-sulfoximine vitamin D3 compounds The present invention provides novel sulfoximine compounds, compositions comprising these compounds and methods of using these compounds as inhibitors of CYP24. In particular, the compounds of the invention are useful for treating diseases which benefit from a modul... | 09/05/2006 |
| 7098014 | ahl-acylase gene This invention provides a gene, qsbA, which encodes a protein useful for inactivating certain bacterial quorum-sensing signal molecules (N-acyl homoserine lactones) which participate in bacterial virulence and biofilm differentiation pathways. This gene was isolated... | 08/29/2006 |
| 7071345 | Method for preparing conjugated polyunsaturated fatty acid esters The claimed method for preparing conjugated polyunsaturated fatty acid esters consisting of an alcohol radical R1 having from 1 to 5 carbon atoms and a fatty acid radical R2 having from 10 to 24 carbon atoms, together with alkoxides having from... | 07/04/2006 |
| 7064190 | Antigen-specific, activated T lymphocytes, detection and use The invention concerns autoreactive peptides, peptide-MHC complexes, T cell subpopulations that react thereto as well as diagnostic and therapeutic applications of these compounds. ... | 06/20/2006 |
| 7052717 | Storage stable thyroxine active drug formulations and methods for their production This invention provides a storage-stable dosage form of a thyroxine active drug composition which exhibits an improved stability. The formulation contains a thyroxine active drug substance and an antioxidant, and, optionally, additional pharmaceutically accepted exc... | 05/30/2006 |
