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...During the Civil War, the Confederacy established its own Patent Office which issued 266 patents, a third of which concerned implements of war.
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| Number | Title | Issue Date |
| 8173371 | Serial coupling of nucleic acid metabolism and extension for nucleic acid amplification A novel method of pyrophosphorolysis activated polymerization (PAP) has been developed. In PAP, pyrophosphorolysis and polymerization by DNA polymerase are coupled serially for each amplification by using an activatable oligonucleotide P* that has a non-extendible 3... | 05/08/2012 |
| 8148065 | Ligation amplification of nucleic acid sequences A method is described for the identification of point mutations by a template-dependent ligation procedure. Also described is a template-dependent ligase chain reaction procedure for the amplification and detection of nucleic acid sequences. ... | 04/03/2012 |
| 8140141 | Devices and methods for fluorescent inspection and/or removal of material in a sample An apparatus is provided that includes a light-emitting component, a light-detecting component, a lock-in amplifier, a frequency generator that is operatively linked to the lock-in amplifier and the light-emitting component, a speaker capable of emitting an audio si... | 03/20/2012 |
| 8138327 | Inducible systems and methods for controlling siRNA expression An inducible system and methods for controlling expression of siRNA are provided. An inducible system for producing siRNA only in the presence of HIV TAT, and methods for inhibiting HIV-1 gene expression in cells comprising such inducible system also are provided. | 03/20/2012 |
| 8138151 | Peptides This invention relates to novel peptides, discovered by using phage display technique, that bind to VAP-1 (Vascular Adhesion Protein-1). The invention concerns also peptides useful as VAP-1 ligands. Such peptides constitute a portion of natural proteins that are pre... | 03/20/2012 |
| 8137974 | Transposition of maize AC/DS elements in vertebrates The present invention is directed to the use of the maize Ac/Ds transposable elements in vertebrates. ... | 03/20/2012 |
| 8129552 | Phospholipids with unsaturated alkyl and acyl chains The invention relates to phospholipid-like compounds having defined apolar constituents and to the use of such compounds as liposomes, active ingredients, and solubilizers. ... | 03/06/2012 |
| 8124655 | Use of LR-90 and LR-102 to overcome insulin resistance The present invention provides methods for ameliorating, overcoming, or inhibiting insulin resistance in a subject, comprising administering to the subject an effective amount of a compound selected from the group consisting of LR-90 and LR-102, or a pharmaceuticall... | 02/28/2012 |
| 8119651 | Compositions useful especially for treatment or prevention of metabolic syndrome This invention relates to a method for treatment or prevention of metabolic syndrome and diseases or conditions resulting therefrom in an individual, wherein an effective amount of an amine oxidase enzyme inhibitor is administered to said individual. In addition, th... | 02/21/2012 |
| 8110549 | Alpha-conotoxin peptides The invention relates to relatively short peptides (termed α-conotoxins herein), about 10-30 residues in length, which are naturally available in minute amounts in the venom of the cone snails or analogous to the naturally available peptides, and which preferably i... | 02/07/2012 |
| D653547 | Package for food products | 02/07/2012 |
| 8106261 | Methods of producing GABA The present invention describes an alternative approach to increase GABA production in prokaryotes or eukaryotes, namely by the insertion of the putrescine catabolic pathway in organisms where the pathway does not exist or has not clearly been identified. The invent... | 01/31/2012 |
| 8101821 | Promotion of somatic embryogenesis in plants by gene expression The present invention relates to methods for promoting somatic embryogenesis from a tissue or organ of a plant, by overexpressing a Wuschel gene in said tissue or organ. In one embodiment, such overexpression can be used as a silent selectable marker for transgenic ... | 01/24/2012 |
| 8101573 | α-conotoxin MII analogs The invention relates to novel conopeptides and/or novel uses of conopeptides. The conopeptides of the invention are analogs of α-Conotoxin MII that are selective for α6-containing nAChRs as described herein. ... | 01/24/2012 |
| 8084599 | Methods and compositions for the specific inhibition of gene expression by double-stranded RNA The invention is directed to compositions and methods for selectively reducing the expression of a gene product from a desired target gene in a cell, as well as for treating diseases caused by the expression of the gene. More particularly, the invention is directed ... | 12/27/2011 |
| 8076520 | Phosphatidyl oligoglycerols In order to form liposomes with a longer half-life in blood, use is made of defined compounds with the general formula (A) ... | 12/13/2011 |
| 8076071 | Methods for producing interfering RNA molecules in mammalian cells and therapeutic uses for such molecules Methods for producing interfering RNA molecules in mammalian cells are provided. Therapeutic uses for the expressed molecules, including inhibiting expression of HIV, are also provided. ... | 12/13/2011 |
| 8071752 | Multi-targeting short interfering RNAs The present invention relates to novel short interfering RNA (siRNA) molecules that are multi-targeted. More specifically, the present invention relates to siRNA molecules that target two or more sequences. In one embodiment, multi-targeting siRNA molecules are desi... | 12/06/2011 |
| 8071296 | Nucleic acid interaction analysis The present invention provides an isolated oligonucleotide and a method using the isolated oligonucleotide to detect and/or identify at least two polynucleotides from a nucleic acid-protein complex. The oligonucleotide comprises at least one first tag and at least o... | 12/06/2011 |
| 8048913 | Compositions and products containing S-equol, and methods for their making A composition for use in making commercial food and skin products comprising S-equol or mixtures, including both a non-racemic mixture and a racemic mixture, of S-equol and R-equol. The composition can be used to make articles of commerce such as food supplements, p... | 11/01/2011 |
| 8017759 | Adenoviral VA1 Pol III promoter system for RNAi expression An adenoviral VA1 Pol III expression system for RNAi expression is provided. ... | 09/13/2011 |
| 8011216 | Method and a storage and locking arrangement for storing keys to locks A method and storage and locking arrangement for storing keys to locks and controlling the use of keys. The storage and locking arrangement consists of a closed box or a similar storage unit, a central lock and its key, as well as a number of auxiliary locks, each h... | 09/06/2011 |
| 7980018 | Handle for fishing rod The present invention concerns a fishing rod for fly fishing, comprising an oblong, thin and elastic body, equipped with a reel for a fishing line, seated on the rod at the lower part of this, along with a gripping device consisting of a fore handle and/or a butt ha... | 07/19/2011 |
| 7978068 | Lost and found tagging and communication system and method A method and system of facilitating communication between a finder of an article and an owner of the article including providing a unique ID to the owner and allowing the owner to register an association between the ID and owner contact information, allowing the own... | 07/12/2011 |
| 7964330 | Electrophotographic resin-coated ferrite carrier, method for producing the same, and electrophotographic developer There are adopted an electrophotographic resin-coated ferrite carrier having a carrier core coated with a resin, wherein a product of an apparent density ρ (g/cm3), average particle size d (μm) and BET specific surface area S (m2/g) of the ca... | 06/21/2011 |
| 7534423 | Method for inducing an elevated level of adenosine in an individual This invention concerns a method of inducing an elevated level of adenosine in an individual by administering to said individual an effective amount of either i) recombinant protein CD73 or ii) a cytokine or another factor-being capable of inducing endothelial CD73 ... | 05/19/2009 |
| 7528267 | Method for enantioselective hydrogenation of chromenes A method for preparing an enantiomeric chromane, by asymmetrically hydrogenating a chromene compound in the presence of an Ir catalyst having a chiral ligand. The method includes the enantioselective preparation of enantiomeric equol. A preferred Ir catalyst has a c... | 05/05/2009 |
| 7504221 | Pyrophosphorolysis activated polymerization (PAP) A novel method of pyrophosphorolysis activated polymerization (PAP) has been developed. In PAP, pyrophosphorolysis and polymerization by DNA polymerase are coupled serially for each amplification by using an activatable oligonucleotide P* that has a non-extendible 3... | 03/17/2009 |
| 7484670 | Blasting method and apparatus Blasting method for cleaning surfaces, wherein a carrier gas is supplied under pressure through a blasting line (10) to a blasting nozzle (14), and liquid CO2 is supplied through a feed line (32), is transformed into dry snow through ... | 02/03/2009 |
| 7486346 | Portable data carrier with a display device having a reflection layer as a separate component and applied separately from the display device A card-shaped electronic data carrier, in particular chip card, has a card body (19) with a recess (21) located on a top side of the card (20), which accommodates a display (1). In a base surface (22) of the recess a reflection lay... | 02/03/2009 |
| 7481755 | Transport shaft for a folding machine A transport shaft for a folding machine includes a shaft body (12), which has an annular cross section, and at least one transport element (14, 16) of annular cross section mounted in a rotationally fixed manner on the shaft body (12). The shaft... | 01/27/2009 |
| 7481458 | Roll-over protection device for a motor vehicle The present invention relates to a roll-over protection device for a motor vehicle, particularly for a convertible, comprising a roll bar (2). This roll bar is provided with an at least nearly U-shaped design having a transverse yoke (3) and lateral li... | 01/27/2009 |
| 7470088 | Method and apparatus for laying a pipeline A method and apparatus for laying an underwater pipeline are provided. The method includes the steps of constructing lengths of pipeline by endwise connection of a plurality of pipe segments and securing bend restriction means along the length of said lengths of pip... | 12/30/2008 |
| 7463339 | Device for measuring the distance to far-off objects and close objects A device for measuring the distances (d) to far-off objects (8) and close objects by emitting modulated laser beams (1) that are reflected on the objects. The device includes an objective (2), structure(s) (12, 36, 38, 39, 40) for selecti... | 12/09/2008 |
| 7425415 | Method for detecting methylated CpG islands The present invention provides new and improved assay for detection of genomic methylated CpG islands. This new method is termed the methylated-CpG island recovery assay (MIRA). In accordance with one embodiment, MIRA comprises the steps of: (a) incubating genomic D... | 09/16/2008 |
| 7420720 | Optical element and method for the production thereof A method for producing an optical element, preferably a security feature, wherein a film having a first embossed hologram in an embossing layer is provided, and a second embossed hologram is embossed into the same embossing layer such that the first embossed hologra... | 09/02/2008 |
| 7421282 | Mobile communication system In a mobile communication system, a mobile switching center 27 changes a transmission rate of communication data transmitted from a mobile station 16 and so on to a database 11 or a transmission rate of communication data transmitted from the da... | 09/02/2008 |
| 7413538 | Epitopes formed by non-covalent association of conjugates A composition for interacting with a ligand, which composition comprises a non-covalent association of a plurality of distinct conjugates, each conjugate comprising a head group and a tail group, wherein the tail groups of the conjugates form a hydrophobic aggregati... | 08/19/2008 |
| 7410012 | Hydraulic automatic boosting pump A hydraulic automatically-pressurizing pump comprises an intermediate fastening connector, a reversing valve, a mechanically-controlled automatic direction-reversing device, a power cylinder, a pressurizing cylinder and an ultrahigh-pressure connecting tube which ar... | 08/12/2008 |
| 7412087 | System and method for monitoring bank notes for the presence of counterfeit bank notes A system and method for monitoring bank notes for the presence of counterfeit bank notes provides for the detection of such data of each bank note to be monitored that permit a judgement to be made on the authenticity of the bank note. By way of the data detected, t... | 08/12/2008 |
