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| Number | Title | Issue Date |
| 7384915 | Chimeric insulin-gad proteins for treating patients with type 1 diabetes or at risk of developing type 1 diabetes Novel chimeric fusion proteins comprising immunodominant epitopes of GAD and insulin are provided. Also provided are immunomodulatory methods for the use of such proteins for both the prevention and treatment of Type 1 diabetes mellitus. The chimeric fusion proteins... | 06/10/2008 |
| 7344499 | Microneedle device for extraction and sensing of bodily fluids Microneedle devices are provided for controlled sampling of biological fluids in a minimally-invasive, painless, and convenient manner. The microneedle devices permit in vivo sensing or withdrawal of biological fluids from the body, particularly from or through the ... | 03/18/2008 |
| 7280943 | Systems and methods for separating multiple sources using directional filtering Systems and methods for performing source separation are provided. Source separation is performed using a composite signal and a signal dictionary. The composite signal is a mixture of sources received by a sensor. The signal dictionary is a database of filtered bas... | 10/09/2007 |
| 7208295 | Multiplex oligonucleotide addition and target amplification Methods for appending oligonucleotides directly to nucleic acid templates, particularly to defined sites internal to single-stranded templates, are described. Appending first and second common priming sites to each of a plurality of templates of distinct sequence al... | 04/24/2007 |
