"To place a man in a multi-stage rocket and project him into the controlling gravitational field of the moon where the passengers can make scientific observations, perhaps land alive, and then return to earth--all that constitutes a wild dream worthy of Jules Verne. I am bold enough to say that such a man-made voyage will never occur regardless of all future advances."
Lee deForest, American radio pioneer ; 1957
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 4735795 | Alkylammonium complexes of diatrizoic acid as X-ray contrast agents New X-ray contrast agents are provided which are alkylammonium complexes of diatrizoic acid having the structure ##STR1## X-ray contrast medium containing the above X-ray contrast agent and a carrier therefor such as a liposome carrier, and a method ... | 04/05/1988 |
| 4735962 | 7-thiabicycloheptane substituted diamide and its congener prostaglandin analogs 7-Thiabicycloheptane substituted diamide and congener prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 1 to 4; A is --CH.dbd.CH-- or --CH2 --CH2 --; n is 1 to 5; R is CO2 H, CO | 04/05/1988 |
| 4734508 | Process and intermediates for preparing 4-substituted proline derivatives A process is provided for preparing 4-hydroxy-4-phenyl-proline derivatives of the structure ##STR1## wherein R1 is a nitrogen protecting group such as benzoyl, benzyloxycarbonyl, t-butoxycarbonyl, benzyl, benzhydryl, trityl, acetyl, t... | 03/29/1988 |
| 4734424 | Bicycloheptane substituted diamide and its congener prostaglandin analogs Bicycloheptane substituted amide prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CH.dbd.CH-- or --CH2 --CH2 --; n is 1 to 5; Q is --CH.dbd.CH--, --CH2 --, ##S... | 03/29/1988 |
| 4734426 | 5,6-epoxy-7-oxabicycloheptane substituted diamide prostaglandin analogs 5,6-Epoxy-7-oxabicycloheptane substituted diamide prostaglandin analogs are provided having the structural formula ##STR1## wherein A is --CH.dbd.CH-- or --CH2 --CH2 --; n is 1 to 5; R is CO2 H, CO2 alkyl, ... | 03/29/1988 |
| 4734425 | 7-oxabicycloheptane substituted hydroxamic acid prostaglandin analogs 7-Oxabicycloheptane substituted hydroxamic acid prostaglandin analogs are provided having the structural formula ##STR1## wherein A is --CH.dbd.CH-- or --CH2 -CH2 --; n is 1 to 5; R is CO2 H, CO2 alkyl, CO | 03/29/1988 |
| 4728670 | Biphenyl hydroxamic acids Biphenyl hydroxamic acids are provided having the structure ##STR1## wherein m is 1 to 7, X is S, O or NH, R is H, lower alkyl, aryl, aralkyl or cycloalkyl and R1 is H, lower alkyl, aryl, aralkyl, cycloalkyl, alkanoyl or aroyl. These compo... | 03/01/1988 |
| 4725440 | Antifungal pastille formulation and method An antifungal pastille formulation, preferably containing nystatin as the antifungal agent, is provided which is soft and smooth in texture and when dissolved slowly in the mouth does not cause irritation of and will not adhere to oral mucosa and yet dist... | 02/16/1988 |
| 4721725 | Aryl-cycloalkyl[b]pyrrole derivatives Aryl-cyclopenta- and arylcyclohexa[b]pyrrole derivatives are provided having the structure ##STR1## wherein n is 1 or 2; X is --OR1 or --NR2 R3 wherein R1 is H, lower alkyl, cycloalkyl, aryl, aralkyl or cyc... | 01/26/1988 |
| 4714714 | Arachidonic acid analogs Analogs of arachidonic acid are provided having the structure ##STR1## wherein R is CH2 OH or CO2 H and m is 1 or 2. These compounds are useful as inhibitors of leukotriene and prostaglandin biosynthesis and as such are useful a... | 12/22/1987 |
| 4711900 | Certain arylalkyl or pyridylalkyl hydroxamates useful for treating allergies and asthma Arylhydroxamates are provided having the structure ##STR1## wherein R1 is hydrogen, lower alkyl, aryl, lower alkenyl, cycloalkyl, or aralkyl; R2 is hydrogen, lower alkyl, aryl, cycloalkyl, alkanoyl or aroyl; m is 2 to 8; and ##S... | 12/08/1987 |
| 4703043 | Phosphonyl hydroxyacyl amino acid derivatives as antihypertensive Phosphonyl hydroxyacyl amino acids of the formula ##STR1## wherein X is a substituted or unsubstituted imino or amino acid or ester. These compounds possess angiotensin converting enzyme activity and are thus useful as hypotensive agents.... | 10/27/1987 |
| 4687865 | Process for preparing 7-oxabicycloheptane amino-alcohol intermediates useful in making thromboxane A2 receptor antagonists A process is provided for preparing a 7-oxabicycloheptane amino alcohol intermediate of the general structure ##STR1## (wherein the above structures represents (D) or (L) isomers) which is useful in preparing thromboxane A2 receptor antago... | 08/18/1987 |
| 4673685 | Hydroximic acids of 7-oxabicycloheptane substituted ethers and thioethers useful in the treatment of thrombotic disease Hydroximic acids of 7-oxabicycloheptane substituted ether and thioether prostaglandin analogs are provided having the structural formula ##STR1## wherein Y is O or ##STR2## and including all stereoisomers thereof. The compounds are inhibitors of... | 06/16/1987 |
| 4670453 | 7-oxabicycloheptane substituted amido-carbamoyl prostaglandin analogs useful in the treatment of thrombotic disease 7-Oxabicycloheptane substituted amidocarbamoyl prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CH.dbd.CH-- or --CH2 --CH2 --; n is 1 to 5; R1 is CO2 H, ... | 06/02/1987 |
| 4670193 | Process for preparing phosphonic acids A process for preparing phosphonic acids of the structure ##STR1## wherein R1 is lower alkyl, aryl, cycloalkyl or arylalkyl, and R2 is H, benzyl or ##STR2## by oxidizing the corresponding phosphonous acid ##STR3## ... | 06/02/1987 |
| 4666705 | Controlled release formulation A controlled release pharmaceutical formulation which undergoes slow release of active drug is provided, preferably in the form of a tablet containing medicament, such as captopril, is slowly released over a controlled length of time. The tablet also incl... | 05/19/1987 |
| 4663336 | 7-oxabicycloheptane substituted diamide and its congener prostaglandin analogs useful in the treatment of thrombotic disease 7-Oxabicycloheptane substituted amide prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CH.dbd.CH-- or --CH2 --CH2 --; n is 1 to 5; Q is --CH.dbd.CH--, --CH2 --, ... | 05/05/1987 |
| 4663337 | 7-oxabicycloheptane substituted amides useful in the treatment of thrombotic disease 7-Oxabicycloheptane substituted amides are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CH.dbd.CH-- or --CH2 --CH2 --; n is 1 to 5; R is CO2 H, CO2 alkyl, CO2 alkal... | 05/05/1987 |
| 4661506 | 7-oxabicycloheptane substituted ox prostaglandin analogs 7-Oxabicycloheptane substituted oxo prostaglandin analogs are provided having the structural formula ##STR1## wherein R1 is lower alkyl, aryl, aralkyl, cycloalkyl or cycloalkylalkyl, A is --CH.dbd.CH-- or --(CH2)2 --,... | 04/28/1987 |
| 4656185 | 7-oxabicycloheptane substituted aminoalkyl amide prostaglandin analogs 7-Oxabicycloheptane substituted diacid diamide prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CH.dbd.CH-- or --CH2 --CH2 --; n is 1 to 5; R is CO2 H, CO2 | 04/07/1987 |
| 4654367 | Hydroxamic acids of 7-oxabicycloheptane substituted ethers useful as anti-allergy and anti-inflammation agents Hydroxamic acids of 7-oxabicycloheptane substituted ether prostaglandin analogs are provided having the structural formula ##STR1## wherein Q is --CH2 --A--(CH2)n --; X is S or O, Y is O or ##STR2## and including... | 03/31/1987 |
| 4654364 | Hydroxamic acids of 7-oxabicycloheptane substituted ethers Hydroxamic acids of 7-oxabicycloheptane substituted ether prostaglandin analogs are provided having the structural formula ##STR1## wherein Y is O or ##STR2## and including all stereoisomers thereof. The compounds are inhibitors of Ɗ5... | 03/31/1987 |
| 4654357 | 7-oxabicycloheptane substituted sulfonamide prostaglandin analogs 7-Oxabicycloheptane substituted sulfonamide prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CH.dbd.CH-- or --CH2 --CH2 --; n is 1 to 5; Q is --CH.dbd.CH--, --CH2 -... | 03/31/1987 |
| 4654356 | 7-oxabicycloheptane substituted diacid diamide prostaglandin analogs 7-Oxabicycloheptane substituted diacid diamide prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CH.dbd.CH-- or --CH2 --CH2 --; n is 1 to 5; Q is --CH.dbd.CH--, --CH2 | 03/31/1987 |
| 4654355 | 7-oxabicycloheptane substituted amide-thioamide prostaglandin analogs 7-Oxabicycloheptane substituted amide-thioamide prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CH.dbd.CH-- or --CH2 CH2 --; n is 1 to 5; Q is --CH.dbd.CH--, --CH2... | 03/31/1987 |
| 4654366 | Hydroxamic acids of 7-oxabicyclo[2.2.1]heptane substituted ethers useful as anti-thrombotic agents 7-Oxabicycloheptane substituted ether or thio ether prostaglandin analogs are provided having the structural formula ##STR1## wherein A is O or ##STR2## and X is O or ##STR3## and including all stereoisomers thereof. The compounds are ... | 03/31/1987 |
| 4652578 | 7-oxabicycloheptane substituted amide prostaglandin analogs Cis-exo 7-oxabicycloheptane substituted amide prostaglandin analogs are provided having the structural formula ##STR1## wherein A is --CH.dbd.CH-- or --CH2 --CH2 --; n is 1 to 5; R is CO2 H, CO2 alkyl, CO | 03/24/1987 |
| 4652576 | 7-oxabicycloheptane substituted amide-carbamate prostaglandin analogs 7-Oxabicycloheptane substituted amide-carbamide prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CH.dbd.CH-- or --CH2 --CH2 --; n is 1 to 5; Q is --CH.dbd.CH--, --CH2 | 03/24/1987 |
| 4647585 | Bicycloheptane substituted ethers Bicycloheptane substituted ether prostaglandin analogs are provided having the structural formula ##STR1## wherein X is O or ##STR2## and including all stereoisomers thereof. The compounds are cardiovascular agents useful, for example, in t... | 03/03/1987 |
| 4647573 | 7-oxabicycloheptane substituted thioamide-amide prostaglandin analogs 7-Oxabicycloheptane substituted thioamideamide prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CH.dbd.CH-- or --CH2 --CH2 --; n is 1 to 5; Q is --CH.dbd.CH--, --CH2 | 03/03/1987 |
| 4639461 | 7-oxabicycloheptane substituted keto-amide prostaglandin analogs useful in the treatment of thrombotic disease 7-Oxabicycloheptane substituted keto-amide prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CH.dbd.CH-- or --CH2 --CH2 --; n is 1 to 5; Q is --CH.dbd.CH--, --CH2 --... | 01/27/1987 |
| 4638012 | 7-oxabicycloheptane -substituted ketone prostaglandin analogs useful in the treatment of thrombotic disease 7-Oxabicycloheptane -substituted ketone prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CH.dbd.CH-- or --CH2 --CH2 --; n is 1 to 5; X is halogen, alkanoyloxy or hydrox... | 01/20/1987 |
| 4638011 | Tetrahydrothienyl substituted prostaglandin analogs Tetrahydrothienyl substituted prostaglandin analogs are provided having the structural formula ##STR1## and including all stereoisomers thereof. The compounds are cardiovascular agents useful, for example, in the treatment of thrombolytic disease.... | 01/20/1987 |
| 4632931 | 7-oxabicycloheptane substituted amide-sulfonamide prostaglandin analogs useful in the treatment of thrombotic disease 7-Oxabicycloheptane substituted amide-sulfonamide prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CH.dbd.CH-- or --CH2 --CH2 --; n is 1 to 5; Q is --CH.dbd.CH--, --CH2 | 12/30/1986 |
| 4627973 | Skin mousse A skin and/or fragrance mousse or foam is provided which is in the form of a light airy stable foam which does not readily break down, and which contains a unique combination of three moisturizers, an alkoxylated methyl glucose derivative such as polyprop... | 12/09/1986 |
| 4626548 | 7-oxabicycloheptane substituted prostaglandin compounds useful in the treatment of thrombotic disease 7-Oxabicycloheptane substituted prostaglandin alcohols are provided having the structural formula ##STR1## wherein A is --CH.dbd.CH-- or (CH2)2 ; m is 1 to 5; Q is --CH.dbd.CH-- or (CH2)2 ; R is H, alkali m... | 12/02/1986 |
| 4618583 | Method of preparing L-(+)-ଲ-hydroxyisobutyric acid by fermentation A method is provided for preparing L-(+)-ଲ-hydroxyisobutyric acid by fermentation employing microorganisms of the species Pseudomonas aeruginosa and of the genus Protaminobacter such as of the species Protaminobacter alboflavus, and isobutyric acid ... | 10/21/1986 |
| 4616005 | Phosphonyl hydroxyacyl amino acid derivatives as antihypertensives Phosphonyl hydroxyacyl amino acids of the formula ##STR1## wherein X is a substituted or unsubstituted imino or amino acid or ester. These compounds possess angiotensin converting enzyme activity and are thus useful as hypotensive agents.... | 10/07/1986 |
| 4614825 | 7-oxabicycloheptane and 7-oxabicycloheptene compounds 7-Oxabicycloheptane and 7-oxabicycloheptene prostaglandin analogs are provided having the structural formula ##STR1## and including all stereoisomers thereof. The compounds are cardiovascular agents useful, for example, in the treatment of thrombolyt... | 09/30/1986 |