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| Number | Title | Issue Date |
| 7427629 | Immunostimulatory compositions and methods of stimulating an immune response The present invention provides immunostimulatory compositions that include an immune response modifier portion paired with an antigenic portion. ... | 09/23/2008 |
| 7308893 | Metered dose dispensers and assemblies therefor A dispensing canister-add-on-component assembly, comprising a dispensing canister comprising a substantially cylindrical container having a closed end and an open end, said open end of the container being equipped by means of a ferrule with a dispensing means; a sub... | 12/18/2007 |
| 7234460 | Metering valve for a metered dose inhaler providing consistent delivery The present invention relates to a novel design for a metering valve that provides improved consistency of formulation delivery. Generally, the metering valve includes (a) a valve stem that generally defines a longitudinal axis and includes a body portion having a m... | 06/26/2007 |
| 7226928 | Methods for the treatment of periodontal disease The disclosure provides methods for the treatment and prevention of periodontal disease. In preferred embodiments, the invention provides for local treatment of periodontal tissues with a pharmaceutical composition including an immune response modifier (IRM) selecte... | 06/05/2007 |
| 7080642 | Refillable device with counting means A refillable medical device comprising a base unit (4) adapted to be engaged with a refill unit (2), the device comprising means for counting the number of different refill units which are engaged with the base unit (4). The device may be in the... | 07/25/2006 |
| 7030129 | Method of reducing and treating UVB-induced immunosuppression Methods of preventing and/or treating UV-induced immunosuppression by administration of immune response modifier compounds are disclosed herein. Suitable immune response modifier compounds include agonists of one or more TLRs. ... | 04/18/2006 |
| 6863195 | Valve stem for use in a metering valve of a metered dose inhaler Valve stems for use in an aerosol metering valve are described herein. The valve stems include structures designed to limit the likelihood and extent to which a gasket can intrude into an opening in the valve stem. The valve stems described herein also limit the lik... | 03/08/2005 |
| 6640805 | Metering valve for a metered dose inhaler having improved flow A novel metering valve having improved flow for delivery of an aerosol formulation is disclosed. Methods of delivering an aerosol formulation using a device comprising the novel metering valve are also disclosed.... | 11/04/2003 |
| 6610319 | Immune response modifier compounds for treatment of TH2 mediated and related diseases Immune response modifier compounds--imidazoquinoline amines, imidazopyridine amines, 6,7-fused cycloalkylimidazopyridine amines, and 1,2-bridged imidazoquinoline amines--are useful for the treatment of TH2 mediated diseases by administering a therapeutica... | 08/26/2003 |
| 6245776 | Formulations and methods for treatment of mucosal associated conditions with an immune response modifier Immune response modifier (IRM) compounds--imidazoquinoline amines, imidazopyridine amines, 6,7-fused cycloalkylimidazopyridine amines, 1,2-bridged imidazoquinoline amines, thiazolo- and oxazolo-quinolinamines and pyridinamines, imidazonaphthyridine and te... | 06/12/2001 |
| 5840744 | Intravaginal treatment of vaginal infections with buffered metronidazole compositions A non-flowing composition and method for treatment of bacterial vaginosis are disclosed. An afflicted vagina is treated with a therapeutically effective but relatively low dose of metronidazole in a composition that includes a buffer system maintaining th... | 11/24/1998 |
| 5776433 | Flunisolide aerosol formulations Pharmaceutical aerosol formulations substantially free of chlorofluorocarbons and comprising a therapeutically effective amount of flunisolide in solution with ethanol and a propellant selected from the group consisting of 1,1,1,2-tetrafluoroethane, ... | 07/07/1998 |
| 5775321 | Seal configuration for aerosol canister A dual seal configuration for an aerosol canister containing a medicinal aerosol formulation. The canister includes a vial body and valve ferrule sealed by first and second sealing members to form a chamber that contains the medicinal aerosol formulation.... | 07/07/1998 |
| 5257823 | Personalizable paper product and method A conveniently personalizable paper product is provided by a piece of folded cardstock paper having one or more die-cut doors in the front half of the paper which, when the paper is folded together, align with designated message areas located on the insid... | 11/02/1993 |