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Attorney: Remy; Brian C.


Number of patents: 102
Last date: April 24, 2012

1      
NumberTitleIssue Date
8163781Bi-aryl aminotetralines
The invention is concerned with the compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein R1-R5, A, B, Q, W, and X are defined in the detailed description and claims...
04/24/2012
8143442Preparation for a cyclohexanecarboxylic acid derivative and intermediates
A process for the preparation of a compound of formula (Ia): which are useful as intermediates in the preparation of i.a. pharmaceutically active compounds. ...
03/27/2012
8138208Aminotetrahydroindazoloacetic acids
The invention is concerned with the compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein Q, W, X, R1-R5 and n are defined in the detailed description and claims. In...
03/20/2012
8124641Aminotetrahydroindazoloacetic acids
The invention is concerned with the compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein Q, R1-R3 and n are defined in the detailed description and claims. In addition, the present inven...
02/28/2012
8124629Naphthylacetic acids
The invention is concerned with the compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein X, Q, and R1-R6 are defined in the detailed description and claims. In addi...
02/28/2012
8071628Indazole derivatives
The invention is concerned with novel indazole derivatives of formula (I) wherein R1, R2, R3, R4, R5, R6, X and Y are as defined in the description and in th...
12/06/2011
8039493Biaryl sulfonamide derivatives
The invention is concerned with novel biaryl sulfonamide derivatives of formula (I) wherein R1 to R3 and Y are as defined in the description and in the claims, as well as physiologically acceptable sal...
10/18/2011
8039487Piperidine-amide derivatives
The invention is concerned with novel piperidine-amide derivatives of formula (I) wherein R1, R2, X and Y are as defined in the description and in the claims, as well as physiologically acceptable salt...
10/18/2011
8008503Methyl-benzimidazole derivatives
The invention is concerned with novel substituted benzimidazole derivatives of formula (I) wherein R1 to R10 are as defined in the description and in the claims, as well as physiologically acceptable s...
08/30/2011
7977509Process for the preparation of acid halides
A process for the preparation of acid halides of formula I which are useful as intermediates in the preparation of i.a. pharmaceutically active compounds. ...
07/12/2011
7928106Aza-pyridopyrimidinone derivatives
The invention is concerned with novel aza-pyridopyrimidinone derivatives of formula (I): wherein R1, R2, R3, R4, R5, X1, X2, X3, Y, Z, ...
04/19/2011
7902184Piperazinyl pyrimidine derivatives
The present invention relates to compounds of formula I and their pharmaceutically acceptable salts wherein formula I is: wherein X, Y, Z, R1 and R2 are as defined in the description and claims. The co...
03/08/2011
78976212-trifluoromethylnicotinamide derivatives as HDL-cholesterol raising agents
The present invention relates to compounds formula I: and pharmaceutically acceptable salts thereof, wherein R1 to R8 are as defined in the description and claims for use as HDL-cholesterol raising age...
03/01/2011
7872141Processes for the manufacture of a pyrrolidine-3,4-dicarboxamide derivative
The invention is concerned with processes for the manufacture of the pyrrolidine-3,4-dicarboxamide derivative of formula (I), and the intermediates useful for those processes of manufacture. ...
01/18/2011
7863474Process for the preparation of CETP(1)
The present invention relates to a process for the preparation of 1-(2-ethyl-butyl)-cyclohexanecarboxylic acid which is useful as an intermediate in the preparation of pharmaceutical active compounds. ...
01/04/2011
7858823Process for cyclohexanecarboxylic acid derivatives
A process for the preparation of a compound of formula (I): which are useful as intermediates in the preparation of i.a. pharmaceutically active compounds. ...
12/28/2010
7858645Indazole derivatives
The invention is concerned with novel indazole derivatives of formula (I) wherein R1, R2, R3, R4, R5, R6, X and Y are as defined in the description and in th...
12/28/2010
7825258Methyl-benzimidazole derivatives
The invention is concerned with novel substituted benzimidazole derivatives of formula (I) wherein R1 to R10 are as defined in the description and in the claims, as well as physiologically acceptable s...
11/02/2010
7824684Methods of inhibiting the binding of P-selectin to PSGL-1 with anti-P-selectin antibodies
This invention relates to anti-P-selectin antibodies and, in particular, to anti-P-selectin antibodies and variants thereof that contain an Fc part derived from human origin and do not bind complement factor C1q. These antibodies have new and inventive properties ca...
11/02/2010
7820699Cyclic amines
The invention is concerned with cyclic amines of formula (I) wherein X1 to X3, Y1 to Y3, R1′, R1″ and n are as defined in the description and in the clai...
10/26/2010
7816540Carboxyl- or hydroxyl-substituted benzimidazole derivatives
This invention relates to novel carboxyl- or hydroxyl-substituted benzimidazole derivatives of formula (I) wherein R1 to R6 are as defined in the description and in the claims, as well as physiological...
10/19/2010
7816342Anti-obesity compositions
The present invention relates to compositions and methods for treating obesity. More particularly, the invention relates to a composition comprising a lipase inhibitor such as orlistat, and glucomannan such as konjac as well as methods for utilizing such composition...
10/19/2010
78120283-pyridinecarboxamide derivatives as HDL-cholesterol raising agents
The present invention relates to a method of raising HDL cholesterol comprising administering to a patient in need thereof a compound of the formula wherein A, G, R1 to R8 and R17 are as def...
10/12/2010
7799933Sulfonamide derivatives
The invention is concerned with novel sulfonamide derivatives of formula (I) wherein R1, R2, R3, X and Y are as defined in the description and in the claims, as well as physiologically accep...
09/21/2010
7790904Substituted benzimidazole derivatives
The invention is concerned with novel substituted benzimidazole derivatives of formula (I) wherein R1 to R10 and X are as defined in the description and in the claims, as well as physiologically accept...
09/07/2010
7786143Thiazolyl piperidine derivatives
The present invention relates to compounds of formula I wherein R1, R2 and R3 are as defined in the description and claims. It further relates to pharmaceutically acceptable salts thereof as...
08/31/2010
7754867Nucleic acid molecules encoding anti-P-selectin antibodies
This invention relates to anti-P-selectin antibodies and, in particular, to anti-P-selectin antibodies and variants thereof that contain an Fc part derived from human origin and do not bind complement factor C1q. These antibodies have new and inventive properties ca...
07/13/2010
7745477Heteroaryl and benzyl amide compounds
Compounds of formula I wherein R1, R2, R4, R5, A, B, D and n are as defined, and pharmaceutically acceptable salts thereof, processes for their preparation, their use as pharmaceu...
06/29/2010
7728171Process for the production of acid chlorides
A process for the preparation of acid halides of formula I which are useful as intermediates in the preparation of i.a. pharmaceutically active compounds. ...
06/01/2010
7718679Heteroaryl carboxamides
The invention is concerned with novel heteroaryl carboxamides of formula (I) wherein A, R1, R2, X, Y, Z and m are as defined in the description and in the claims, as well as physiologically acceptable ...
05/18/2010
7718659Heteroarylacetamide inhibitors of factor Xa
The invention is concerned with novel heteroarylacetamides of formula (I) Rd—C(O)—N(Re)—Rc—CH2—C(O)—N(Ra)(Rb)  (I) wherein Ra to Re are as def...
05/18/2010
7705034Vinylogous acid derivatives
The invention is concerned with novel vinylogous acid derivatives of formula I: wherein A and R1 to R5 are as defined in the description and in the claims, as well as physiologically acceptable salts t...
04/27/2010
7696240Fused pyrrole derivatives
The invention is concerned with novel fused pyrrole derivatives of formula (I) wherein A, Ar, R1, R2, R2′ and R2″ and n are as defined in the description and in the claims, as...
04/13/2010
7691876Heterobicyclic amide compounds
Compounds of formula I processes for their preparation and pharmaceutical compositions comprising them. ...
04/06/2010
7691863Pyrazine-2-carboxamide derivatives as CB2 receptor modulators
The present invention relates to compounds of the formula wherein R1 to R4 are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the ...
04/06/2010
7678917Factor Xa inhibitors
The invention is concerned with novel cycloalkane carboxamides of formula (I) wherein X, X1, Y, Y1, R1′, R1″, R2, R3, m and n are as defined in the descr...
03/16/2010
7678818Anthranilamide and 2-amino-heteroarene-carboxamide compounds
Compounds of formula I processes for their preparation, their use as pharmaceuticals and to pharmaceutical compositions comprising them. ...
03/16/2010
7674815Heteroaryl and benzyl amide compounds
Compounds of formula I processes for their preparation, their use as pharmaceuticals and to pharmaceutical compositions comprising them. ...
03/09/2010
76489795-amido-(1H-indol-2-yl)-piperazin-1-yl-methanone derivatives
The present invention relates to compounds of formula I wherein A, G and R1 to R3 are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful f...
01/19/2010
7645785Benzimidazole derivatives
The invention is concerned with novel benzimidazole derivatives of formula (I) wherein R1 to R8 are as defined in the description and in the claims, as well as physiologically acceptable salts and este...
01/12/2010
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