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| Number | Title | Issue Date |
| 6072014 | Multimodal polymer compositions prepared using multinuclear metallocene catalysts A process is provided for preparing polymer compositions which are multimodal in nature. The process involves contacting, under polymerization conditions, a selected addition polymerizable monomer with a metallocene catalyst having two or more distinct an... | 06/06/2000 |
| 6061115 | Method of producing a multi-domain alignment layer by bombarding ions of normal incidence Methods for producing a multi-domain alignment layer, as well as the multi-domain alignment layers produced thereby and liquid crystal displays comprising the same, are provided. In the subject methods, a surface of an alignment film, usually present on a... | 05/09/2000 |
| 6055447 | Patient CO2 Measurement A method and apparatus are provided for assessing impairment of blood circulation of a patient by measurement of PCO2 (partial pressure of carbon dioxide) in the upper digestive/respiratory tract of the patient. The method includes introducing ... | 04/25/2000 |
| 6054446 | Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use Novel anti-estrogenic compounds are provided which are useful to treat a variety of disorders, particularly estrogen-dependent disorders. Preferred compounds have a 1,3,5-estratriene nucleus, and are substituted at the C-17 or C-11 position with a molecul... | 04/25/2000 |
| 6048992 | Metallocene compounds from amino alcohol-derived ligands A method is provided for synthesizing metallocene compounds useful as polymerization catalysts and the like. The method involves (a) preparation of an amino alcohol-derived ligand by reacting a silane reactant with an amino alcohol in the presence of base... | 04/11/2000 |
| 6048851 | Solid pharmaceutical compositions for the oral administration of gallium The subjects of this invention are pharmaceutical compositions that comprise gallium complexes of 3-hydroxy-4-pyrones. The compositions have been developed to provide pharmaceutically acceptable gallium bioavailability together with low toxicity, particul... | 04/11/2000 |
| 6046186 | Estrone sulfamate inhibitors of estrone sulfatase, and associated pharmaceutical compositions and methods of use Novel compounds useful as inhibitors of estrone sulfatase are provided. The compounds have the structural formula (I) wherein r1 is an optional double bond, R1 and R2 are selected from the group consisting of hydrogen and lower alky,... | 04/04/2000 |
| 6037346 | Local administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction A method is provided for treating erectile dysfunction in a mammalian male individual. The method involves the local administration of a phosphodiesterase inhibitor or a pharmaceutically acceptable salt, ester, amide or derivative thereof within the conte... | 03/14/2000 |
| 6022901 | Administration of resveratrol to prevent or treat restenosis following coronary intervention A method for preventing or treating restenosis and for preventing the recurrence or progression of coronary heart disease is provided. The method involves administration of a selected active agent to a patient following coronary intervention, e.g., corona... | 02/08/2000 |
| 6004951 | Administration of gallium complexes of 3-hydroxy-4-pyrones to provide physiologically active gallium levels in a mammalian individual Disclosed are pharmaceutical compositions that comprise gallium complexes of 3-hydroxy-4-pyrones. These compositions provide enhanced gallium bioavailability particularly when orally administered as compared to the gallium bioavailability achieved by use ... | 12/21/1999 |
| 5990024 | Dehydrocoupling treatment and hydrosilylation of silicon-containing polymers, and compounds and articles produced thereby Novel methods for the preparation of polymers useful as precursors to ceramic materials by catalytic activation of Si--H bonds are disclosed. The methods comprise reacting, in the presence of a catalyst effective to activate Si--H bonds, Si--N bonds, or b... | 11/23/1999 |
| 5986024 | Preparation of multimodal polymer compositions using multinuclear metallocene catalysts A process is provided for preparing polymer compositions which are multimodal in nature. The process involves contacting, under polymerization conditions, a selected addition polymerizable monomer with a metallocene catalyst having two or more distinct an... | 11/16/1999 |
| 5976085 | In situ calibration system for sensors located in a physiologic line A method is provided for calibrating sensors used to analyze characteristics of physiologic fluids such as blood. The method involves the use of a sensor assembly having an analyte-responsive sensor in communication with a passageway which is in divertabl... | 11/02/1999 |
| 5976666 | Electromagnetic radiation absorbing devices and associated methods of manufacture and use Novel devices for providing shielding from and absorption of broadband electromagnetic radiation, and methods of manufacturing and using these devices, are disclosed. The device is comprised of a perforated electrical absorbing layer, containing conductiv... | 11/02/1999 |
| 5958853 | Solid, water-degradable disinfectant and cleanser composition, and associated methods of manufacture and use A disinfectant and cleansing composition is provided in the form of an extruded solid. The active agent in the composition is a halogen-releasing agent such as a halogenated 5,5-dialylhydantoin. An inert binder such as a fatty acid salt or a hectoritic cl... | 09/28/1999 |
| 5944660 | Disposable cartridge assembly with optional integrated temperature control system, and systems containing same A cartridge assembly is provided for analyzing characteristics of a sample fluid. The cartridge assembly comprises an assembly body having a passageway, a cavity and, interposed between the passageway and the cavity, a manifold containing a port that serv... | 08/31/1999 |
| 5919572 | Temperature-resistant and/or nonwetting coating of cured, silicon-containing polymers Surfaces of various types of substrates, including glass, ceramics, metals and fabrics, are rendered thermally stable by treatment with a silicon-containing polymer which may be a polysilazane, a polysiloxane, or a polysiloxazane. Curing the polymer in an... | 07/06/1999 |
| 5919474 | Transurethral administration of vasoactive agents to treat peripheral vascular disease, related vascular diseases, and vascular impotence associated therewith A method for treating peripheral vascular disease (PVD), related vascular diseases, and vascular impotence associated with such diseases, is provided. The method involves transurethral administration of a pharmaceutical formulation containing a selected v... | 07/06/1999 |
| 5686132 | Glucans having a cycle structure, and processes for preparing the same The present invention provides glucans and derivatives thereof which are useful as raw materials in the starch processing industries, food and drink compositions, food additive compositions, and starch substitutes for biodegradable plastics, and processes... | 11/11/1997 |
| 5672515 | Simultaneous dual excitation/single emission fluorescent sensing method for PH and pCO2 A simultaneous dual excitation/single emission ratiometric method using fiber optic sensors is provided for detecting or measuring a parameter of interest in a sample, including pH, concentration of gases such as CO2, and the like. The method i... | 09/30/1997 |
| 5672491 | Recombinant production of novel polyketides Novel polyketides and novel methods of efficiently producing both new and known polyketides, using recombinant technology, are disclosed. In particular, a novel host-vector system is described which is used to produce polyketide synthases which in turn ca... | 09/30/1997 |
| 5656241 | Method for manufacturing fiber optic sensors A method is provided-for manufacturing a fiber optic sensor for detecting or measuring a parameter of interest in a sample fluid, including pH, concentration of dissolved gases such as O2 or CO2, and the like. The sensing chemistry i... | 08/12/1997 |
