Did You Know...
...that while attempting to develop a super strong glue, 3M employee Spencer Silver accidentally developed a glue that was so weak it would barely hold two pieces of paper together? However, his colleague Art Fry needed the glue. Fry sang with his church choir and marked the pages of his hymnal with small scraps of paper that often fell out. He used Silver's glue to hold the papers in place. Today we call this invention Post-it Notes.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 5714142 | Method and compositions for increasing the serum half-life of pharmacologically active agents by binding to transthyretin-selective ligands Compositions and methods are provided for increasing the serum half-life of a pharmacologically active agent. The novel compositions are covalent conjugates of the selected pharmacologically active agent and a transthyretin-binding ligand such as tetraiio... | 02/03/1998 |
| 5681697 | Solution phase nucleic acid sandwich assays having reduced background noise and kits therefor New techniques are provided for substantially reducing background signals encountered in solution phase hybridization assays. The techniques are premised on eliminating or significantly reducing the phenomena of nonspecific hybridization and nonspecific b... | 10/28/1997 |
| 5597909 | Polynucleotide reagents containing modified deoxyribose moieties, and associated methods of synthesis and use Methods and reagents are provided for synthesizing polynucleotides containing modified deoxyribose residues. Monomeric reagents having the structural formula (I) ##STR1## wherein R1, R2, R3, R4 and R5 | 01/28/1997 |
| 5594117 | Polynucleotide reagents containing modified deoxyribose moieties and associated methods of synthesis and use Methods and reagents are provided for synthesizing polynucleotides containing modified deoxyribose residues. Monomeric reagents having the structural formula (I) ##STR1## wherein R1, R2, R3, R4 and R5 | 01/14/1997 |
| 5591584 | N-4 modified pyrimidine deoxynucleotides and oligonucleotide probes synthesized therewith Novel oligonucleotide probes are provided having the structure ##STR1## wherein: R2 is lower alkyl; R3 is C1 -C12 alkylene containing 0 to 6 linkages selected from the group consisting of --O--, --S-- and -... | 01/07/1997 |
| 5380833 | Polynucleotide reagents containing selectable cleavage sites Novel methods for assaying a nucleic acid analyte are provided, which employ polynucleotides having oligonucleotide sequences substantially homologous to a sequence of interest in the analyte, where the presence or absence of hybridization at a predetermi... | 01/10/1995 |
| 5332845 | Phosphorylating reagents Novel phosphorylating reagents are provided which are useful in DNA synthesis and purification procedures. The reagents are substituted phosphines which are particularly useful in the phosphorylation of nucleoside and solid supported oligonucleotides at t... | 07/26/1994 |
| 5258506 | Photolabile reagents for incorporation into oligonucleotide chains Novel photolabile photochemical reagents are disclosed. The reagents are useful in a variety of biochemical and chemical contexts, including nucleic hybridization assays and chemical phosphorylation of hydroxyl-containing compounds. The reagents are parti... | 11/02/1993 |
| 5256549 | Purification of synthetic oligomers Oligomers and polymers are prepared substantially free of error sequences by sequentially adding monomers, which are terminally blocked and have active functionalities protected, to a growing chain bound to a support through a selectively cleavable linkag... | 10/26/1993 |
