Did You Know...
...that a workman who left the soap mixing machine on too long was responsible for making Ivory Soap? He was so embarrassed by his mistake that he threw the mess in a stream. Imagine his dismay when the evidence of his error floated to the surface! Result: Ivory soap, the soap that floats.
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| Number | Title | Issue Date |
| 7399817 | Olefin copolymers containing hydrolytically cleavable linkages and use thereof in degradable products The invention is directed to olefin copolymers composed of nonhydrolyzable monomer units and hydrolyzable monomer units, the latter resulting from copolymerization of monomers containing a linkage that is hydrolytically cleavable in the presence of aqueous base or a... | 07/15/2008 |
| 7365140 | Transition metal carbene complexes containing a cationic substituent as catalysts of olefin metathesis reactions Organometallic complexes suitable as olefin metathesis catalysts are provided. The complexes are Group 8 transition metal carbenes bearing a cationic substituent and having the general structure (I) wherein M is a Group 8 t... | 04/29/2008 |
| 7358027 | Copolymer for use in chemical amplification resists A copolymer is provided for use in a lithographic photoresist composition, particularly a chemical amplification photoresist. In a preferred embodiment, the copolymer is substantially transparent to deep ultraviolet radiation, i.e., radiation of a wavelength less th... | 04/15/2008 |
| 7329687 | Flavanoid compounds as chemotherapeutic, chemopreventive, and antiangiogenic agents Compounds useful as chemotherapeutic, chemopreventive, and antiangiogenic agents are provided. The compounds are flavanoids, including flavanones, flavanols, and chalcones. The compounds have the structure of formula (I) | 02/12/2008 |
| 7297811 | Precursors to fluoroalkanol-containing olefin monomers and associated methods of synthesis and use The invention provides alkene fluoroalkanol and fluorinated polyol precursors to fluoroalkanol-substituted α,β-unsaturated esters. The fluoroalkanol-substituted α,β-unsaturated esters are olefins that can be readily polymerized to provide fluoroalkanol-substitut... | 11/20/2007 |
| 7285320 | Preparation of images on a substrate surface utilizing an opaque coating composition that becomes transparent upon printing The present invention features processes and compositions for producing a metallic-looking image on a substrate having a reflective or luminescent surface. The process utilizes an opaque coating composition containing an opaque coating agent comprising a mixture of ... | 10/23/2007 |
| 7270986 | Ejection of localized volumes from fluids A method is provided for acoustically ejecting from a channel or other container a plurality of fluid droplets, each of which contains one or more particles or other localized volumes. The localized volumes, which can be living cells, are ejected towards sites on a ... | 09/18/2007 |
| 7265249 | Enantioselective alpha-fluorination of aldehydes using chiral organic catalysts Nonmetallic, chiral organic catalysts are used to catalyze enantioselective fluorination of enolizable aldehydes. Reaction systems composed of an enolizable aldehyde, an electrophilic fluorination reagent, and a nonmetallic chiral catalyst in the form of an imidazol... | 09/04/2007 |
| 7262315 | Transition metal oxo, sulfido and amido complexes as catalysts of nucleophilic addition reactions Methods are provided for carrying out nucleophilic addition reactions using oxo, sulfido or amido complexes of transition metals as reaction catalysts. Exemplary catalysts are oxo complexes of Group 7 transition metals, with rhenium (V) oxo complexes, including diox... | 08/28/2007 |
| 7235698 | Enantioselective, catalytic allylation of ketones and olefins Compounds containing a substituted or unsubstituted allyl group directly bound to a chiral carbon atom are prepared enantioselectively. Starting reactants are either chiral or achiral, and may or may not contain an attached allyloxycarbonyl group as a substituent. C... | 06/26/2007 |
| 7232842 | Kinase inhibitors and associated pharmaceutical compositions and methods of use The invention provides novel compounds useful as kinase inhibitors or as starting materials And/or intermediates in the synthesis of compounds useful as kinase inhibitors. The compounds have The general structure of formula (I) | 06/19/2007 |
| 7090333 | Focused acoustic energy in the preparation of peptide arrays The present invention relates to arrays of peptidic molecules and the preparation of peptide arrays using focused acoustic energy. The arrays are prepared by acoustically ejecting peptide-containing fluid droplets from individual reservoirs towards designated sites ... | 08/15/2006 |
| 7070260 | Droplet dispensation from a reservoir with reduction in uncontrolled electrostatic charge Devices and methods are provided for reducing the uncontrolled electrostatic charges that can alter the volume and/or trajectory of a droplet, which is typically ejected through the application of focused acoustic radiation. Also provided are reservoirs and substrat... | 07/04/2006 |
| 7067701 | Preparation of phosphorus-containing compounds useful in the preparation of biphosphine ligands This invention relates to processes for making phosphorus compounds R2P—X—PR2, R2P-M, R2P-L and R3P, and the novel cation R2P+(L)-X—P+(L)R2, where R represents a... | 06/27/2006 |
| 7056890 | Combination therapy for effecting weight loss and treating obesity The present invention features a novel therapy for effecting weight loss which involves treating a subject with a sympathomimetic agent (e.g., phentermine or a phentermine-like drug) in combination with an anticonvulsant sulfamate derivative (e.g., topiramate) such ... | 06/06/2006 |
| 7037992 | Olefin copolymers containing hydrolytically cleavable linkages and use thereof in degradable products The invention is directed to olefin copolymers composed of nonhydrolyzable monomer units and hydrolyzable monomer units, the latter resulting from copolymerization of monomers containing a linkage that is hydrolytically cleavable in the presence of aqueous base or a... | 05/02/2006 |
| 6991917 | Spatially directed ejection of cells from a carrier fluid This invention is directed to the use of focused energy, particularly focused acoustic energy, in the spatially directed ejection of cells suspended in a carrier fluid, e.g., for providing a pattern of cells on a substrate surface, such as a cellular array. ... | 01/31/2006 |
| 6987154 | Synthesis of A,B-alternating copolymers by olefin metathesis reactions of cyclic olefins or olefinic polymers with an acyclic diene This invention relates generally to synthetic procedures that include the step of ring-opening metathesis of cyclic olefins and reaction with an acyclic diene co-reactant to produce regularly repeating A,B-alternating olefin polymers. The A,B-alternating polymers ar... | 01/17/2006 |
| 6982281 | Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs, particularly fenofibrate, are provided. The compositions comprise a therapeutically effective amount of an active agent and a solubilizer. The solubilizer is selected to effectivel... | 01/03/2006 |
| 6946533 | Synthesis of macrocyclic polymers by ring insertion polymerization of cyclic olefin monomers A method for synthesizing cyclic polymers using transition metal alkylidene complexes as reaction catalysts is provided, wherein the complexes contain a cyclic group. Polymerization is carried out on the catalyst, using cyclic olefin monomers that undergo ring inser... | 09/20/2005 |
| 6946141 | As-needed administration of tricyclic and other non-SRI antidepressant drugs to treat premature ejaculation A method is provided for treatment of premature ejaculation by administration of an antidepressant drug selected from tricyclic antidepressants, tetracyclic antidepressants, MAO inhibitors, azaspirone antidepressants, and atypical non-SRI antidepressants. In a prefe... | 09/20/2005 |
| 6940692 | Magnetic recording head having a corrosion-protective layer of a metal salt of a perfluorinated polyether acid A process is provided for synthesizing metal salts of perfluorinated polyethers containing at least one carboxylic acid group. The polymeric salts so provided are effective as anti-wetting and corrosion-protective agents. The metal salts of perfluorinated polyether ... | 09/06/2005 |
| 6938995 | Acoustic assessment of fluids in a plurality of reservoirs The invention provides devices and methods for acoustically assessing the contents of a plurality of reservoirs that are typically provided as an array. An acoustic radiation generator is employed for generating acoustic radiation having an image field of a size suf... | 09/06/2005 |
| 6938987 | Acoustic ejection of fluids from a plurality of reservoirs The present invention provides a method and device for the acoustic ejection of fluid droplets from each of a plurality of fluid-containing reservoirs. The droplets are ejected toward sites on a substrate surface for deposition thereon. The device is comprised of: a... | 09/06/2005 |
| 6916955 | Process for synthesizing perfluorinated polyethers with metal carboxylate end groups A process is provided for synthesizing metal salts of perfluorinated polyethers containing at least one carboxylic acid group. The polymeric salts so provided are effective as anti-wetting and corrosion-protective agents. The metal salts of perfluorinated polyether ... | 07/12/2005 |
| 6900357 | Direct, enantioselective aldol coupling of aldehydes using chiral organic catalysts Nonmetallic, chiral organic catalysts are used to catalyze an enantioselective aldol coupling reaction between aldehyde substrates. The reaction may be carried out with a single enolizable aldehyde, resulting in dimerization to give a β-hydroxy aldehyde, or trimeri... | 05/31/2005 |
| 6893836 | Spatially directed ejection of cells from a carrier fluid This invention is directed to the use of focused energy, particularly focused acoustic energy, in the spatially directed ejection of cells suspended in a carrier fluid, e.g., for providing a pattern of cells on a substrate surface, such as a cellular array. ... | 05/17/2005 |
| 6893115 | Frequency correction for drop size control The present invention provides a method and device for the acoustic ejection of fluid droplets having a constant drop size from fluid-containing reservoirs having varying fluid heights contained therein without the need for repositioning the acoustic ejector in the ... | 05/17/2005 |
| 6884859 | Ring-opening metathesis polymerization of bridged bicyclic and polycyclic olefins containing two or more heteroatoms A method is provided for synthesizing a polymer in a controlled fashion using a ring-opening metathesis polymerization (ROMP) reaction, wherein polymerization is carried out using a catalytically effective amount of an olefin metathesis catalyst and a bridged bicycl... | 04/26/2005 |
| 6874668 | Telescoped multiwall nanotube and manufacture thereof The invention relates to a method for forming a telescoped multiwall nanotube. Such a telescoped multiwall nanotube may find use as a linear or rotational bearing in microelectromechanical systems or may find use as a constant force nanospring. In the method of the ... | 04/05/2005 |
| 6869551 | Precipitation of solid particles from droplets formed using focused acoustic energy Methods and devices are disclosed that use focused acoustic energy to generate solid particles containing at least one compound of interest. Focused acoustic radiation serves to eject droplets containing a compound of interest dissolved in a solvent. The droplets ar... | 03/22/2005 |
| 6867274 | Telechelic alkadiene polymers with crosslinkable end groups and methods for making the same The present invention relates to telechelic polymers having crosslinkable end groups of the formula and methods for preparing the same wherein n is an integer; is an alka... | 03/15/2005 |
| 6855925 | Methods, devices, and systems using acoustic ejection for depositing fluid droplets on a sample surface for analysis Provided is a method for preparing a sample surface for analysis that involves placing a sample surface in droplet-receiving relationship to a reservoir containing an analysis-enhancing fluid. Typically, the analysis-enhancing fluid is comprised of a mass spectromet... | 02/15/2005 |
| 6849423 | Focused acoustics for detection and sorting of fluid volumes A method is provided for acoustically ejecting from a channel or other container a plurality of fluid droplets, each of which contains one or more particles or other localized volumes. The localized volumes, which can be living cells, are ejected towards sites on a ... | 02/01/2005 |
| 6841676 | Complexes of mid-transition metals and unsaturated nitrogenous ligands as single-site catalysts Novel compounds are provided which are useful as catalysts, particularly in the polymerization of addition polymerizable monomers such as olefinic or vinyl monomers. The compounds are complexes of a mid-transition metal coordinated to at least two ligands, at least ... | 01/11/2005 |
| 6835392 | Dual enhancer composition for topical and transdermal drug delivery A permeation enhancer composition is provided for increasing the permeability of skin or mucosal tissue to topically or transdermally administered pharmacologically or cosmeceutically active agents. The composition is comprised of a hydroxide-releasing agent and a l... | 12/28/2004 |
| 6833408 | Methods for tissue repair using adhesive materials A method of tissue repair is provided using a biocompatible nonimmunogenic adhesive composition. The adhesive composition comprises collagen and a plurality of crosslinkable components having reactive functional groups thereon, with the functional groups selected so... | 12/21/2004 |
| RE38676 | Thermally initiated polymerization of olefins using ruthenium or osmium vinylidene complexes The present invention generally relates to the use of certain ruthenium and osmium complexes that are substantially inactive at a first temperature (preferably about room temperature) but becomes progressively more active at a higher second temperature. This differe... | 12/21/2004 |
| 6821523 | Topical administration of pharmacologically active bases in the treatment of warts Provided are methods and topical pharmaceutical formulations for use in the treatment of warts. The invention involves the topical administration of a pharmacologically active base in a formulation having a pH of about 7.5 to about 13.0, preferably about 8.0 to 11.5... | 11/23/2004 |
| 6815064 | Luminescent nanoparticles and methods for their preparation Methods for synthesizing luminescent nanoparticles and nanoparticles prepared by such methods are provided. The nanoparticles are prepared by a method in which an additive is included in the reaction mixture. The additive may be a Group 2 element, a Group 12 element... | 11/09/2004 |
