...that Charles Goodyear performed some of his experiments on rubber while in debtor's prison? He was there so often he referred to it as his "hotel". Chronically in debt because of poor business sense and ill health, Goodyear depended on the generosity of friends and family. Even after he unlocked the secret to vulcanizing rubber, he was unable to improve his financial situation. When he died, his estate was $200,000 in debt.
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| Number | Title | Issue Date |
| 6592904 | Dispersible macromolecule compositions and methods for their preparation and use A process for preparing ultrafine powders of biological macromolecules comprises atomizing liquid solutions of the macromolecules, drying the droplets formed in the atomization step, and collecting the particles which result from drying. By properly contr... | 07/15/2003 |
| 6576262 | Methods and apparatus for particle formation The invention provides a method for forming particles of a target substance (26), involving: (a) preparing a solution or suspension of the substance in a vehicle (21) which is or includes either a near-critical fluid (21) or a first supercritical fluid; (... | 06/10/2003 |
| 6572894 | Process for the production of morphologically uniform microcapsules and microcapsules that are produced according to this process The invention relates to a process for the production of morphologically uniform microcapsules that contain peptides, proteins or other water-soluble biologically active substances as active ingredients as well as microcapsules that are produced according... | 06/03/2003 |
| 6572893 | Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients Methods for preparing dry powders having hydrophobic and hydrophilic components comprise combining solutions of the components and spray drying them simultaneously in a spray dryer. The hydrophilic and hydrophobic component are separately dissolved in sep... | 06/03/2003 |
| 6565885 | Methods of spray drying pharmaceutical compositions Spray drying methods for forming powder compositions for pharmaceutical applications are disclosed. According to one aspect of the invention, the spray drying feed stock comprises a bioactive agent, surfactant, and a blowing agent. Another aspect of the i... | 05/20/2003 |
| 6440337 | Method and apparatus for the formation of particles The invention provides a method and apparatus for forming particles of a substance, comprising (a) introducing into a particle formation chamber, the temperature and pressure in which are controlled, a first supercritical fluid (SCF) and a solution or sus... | 08/27/2002 |
| 6423344 | Dispersible macromolecule compositions and methods for their preparation and use A process for preparing ultrafine powders of biological macromolecules comprises atomizing liquid solutions of the macromolecules, drying the droplets formed in the atomization step, and collecting the particles which result from drying. By properly contr... | 07/23/2002 |
| 6365190 | Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients Methods for preparing dry powders having hydrophobic and hydrophilic components comprise combining solutions of the components and spray drying them simultaneously in a spray dryer. The hydrophilic and hydrophobic component are separately dissolved in sep... | 04/02/2002 |
| 6309623 | Stabilized preparations for use in metered dose inhalers Stabilized dispersions are provided for the delivery of a bioactive agent to the respiratory tract of a patient. The dispersions preferably comprise a plurality of perforated microstructures dispersed in a suspension medium that typically comprises a hydr... | 10/30/2001 |
| 6294204 | Method of producing morphologically uniform microcapsules and microcapsules produced by this method The invention relates to a process for the production of morphologically uniform microcapsules that contain peptides, proteins or other water-soluble biologically active substances as active ingredients as well as microcapsules that are produced according... | 09/25/2001 |