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"The abolishment of pain in surgery is a chimera. It is absurd to go on seeking it...knife and pain are two words in surgery that must forever be associated in the consciousness of the patient."
Dr. Alfred Velpeau, French surgeon ; 1839
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| Number | Title | Issue Date |
| 5217878 | Molecular cloning and expression of genes encoding proteolytic enzymes Novel methods and novel industrial Bacillus strains are provided for enhanced production of serine protease. Plasmid constructs comprising the serine protease gene are introduced into a compatible host, generally a Bacillus already overproducing serine pr... | 06/08/1993 |
| 5173402 | Method and compositions for screening and diagnosing human cytomegalovirus ("hCMV") DNA sequences of hCMV are obtained by restriction of the hCMV genome, the resulting fragments free of fragments cross-hybridizing with human DNA and other viruses may be used for hybridization with clinical samples suspected of containing hCMV to provide ... | 12/22/1992 |
| 5164316 | DNA construct for enhancing the efficiency of transcription Novel transcription initiation regions that provide for enhanced transcription of a DNA sequence, particularly a plant sequence, are provided.... | 11/17/1992 |
| 5107065 | Anti-sense regulation of gene expression in plant cells Regulation of expression of genes encoded for in plant cell genomes is achieved by integration of a gene under the transcriptional control of a promoter which is functional in the host and in which the transcribed strand of DNA is complementary to the str... | 04/21/1992 |
| 5094945 | Inhibition resistant 5-enolpyruvyl-3-phosphoshikimate synthase, production and use Enhanced resistance to glyphosate, an inhibitor of the aromatic amino acid biosynthesis pathway, is imparted to a glyphosate sensitive host. A mutated aroA gene is employed which expresses 5-enolpyruvyl-3-phosphoshikimate synthase (EC: 2.5.1.19) (ES-3-P ... | 03/10/1992 |
| 5068193 | Novel method and compositions for introducing alien DNA in vivo Method and compositions are provided for introducing alien DNA into a nucleic acid in vivo by providing a plasmid capable of replication in a first host, which is capable of conjugation with a second host into which the alien DNA is to be introduced. The ... | 11/26/1991 |
| 5063150 | Retroviral polypeptides associated with human cellular transformation Polypeptides, fragments thereof, antisera and monoclonal antibodies thereto are provided for the detection of retroviruses in the HTLV family capable of inducing transformation in human lymphocytes and other immune cells, regulation of viral replication a... | 11/05/1991 |
| 5017558 | Synthetic vaccine peptide epitomes of hepatitis B surface antigen Novel oligopeptides are provided having serologic activity for the a determinant of hepatitis B virus surface antigen. Included in the oligopeptide chain are a sequence of at least two cysteines and a lysine in proximity to the cysteines. The oligopeptide... | 05/21/1991 |
| 4997761 | Phosphatidyl treatment of viral disease Phosphatides are shown to have antiviral activity, where the phosphatides are characterized by having a polyunsaturated fatty acid at the sn2 position. By contacting cells susceptible to or infected with a virus, particularly a retrovirus, the proliferati... | 03/05/1991 |
| 4996144 | Microassay for detection of DNA and RNA A novel hybridization diagnostic technique is involved employing micromanipulation of cells for detection of DNA or RNA in the cells. Cellular suspensions are employed, the DNA or RNA purified by microextraction using liquid media having differential solu... | 02/26/1991 |
| 4956282 | Mammalian peptide expression in plant cells Novel constructs are provided for expression of physiologically active mammalian proteins in plant cells, either in culture or under cultivation. The constructs provide a promoter functional in a plant host, a structural gene coding for mammalian protein ... | 09/11/1990 |
