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Attorney: Quine; Jonathan Alan


Number of patents: 34
Last date: November 01, 2011

NumberTitleIssue Date
8049067Organogenic transformation and regeneration
This invention provides methods of transforming organogenic plant cells and regenerating plants from transformed cells. ...
11/01/2011
8030028Compositions of orthogonal lysyl-tRNA and aminoacyl-tRNA synthetase pairs and uses thereof
Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal lysyl-tRNAs, orthogonal lysyl-aminoacyl-tRNA synthetases, and orthogonal pairs of lysyl-tRNAs/synthetases, which incorporate homoglutamines into proteins are p...
10/04/2011
7960116Nucleic acid sequencing methods and systems
Sequencing methods that use an exonuclease that comprises template dependent nucleobase binding activity are provided. Related compositions and sequencing systems are also provided. ...
06/14/2011
7601883Mammalian sour/acid taste and CSF receptor genes, polypeptides and assays
Acid/sour taste receptors are provided. CSF pH sensing receptors are provided. Methods and systems for screening for tastants and receptor modulators are provided. Knock out and transgenic animals, antibodies to the receptors, methods of detecting polymorphisms, and...
10/13/2009
7575895Compositions of orthogonal lysyl-tRNA and aminoacyl-tRNA synthetase pairs and uses thereof
Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal lysyl-tRNAs, orthogonal lysyl-aminoacyl-tRNA synthetases, and orthogonal pairs of lysyl-tRNAs/synthetases, which incorporate homoglutamines into proteins are p...
08/18/2009
7432092Site specific incorporation of keto amino acids into proteins
Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases, which incorporate keto amino acids into proteins are provided. Methods...
10/07/2008
7407769Method of identifying activity modulators of a polycystin-2L1 taste receptor polypeptide
Taste receptor polycystin-2L1 is provided. Methods and systems for screening for tastants and receptor modulators are provided. Knock out and transgenic animals, methods of detecting polymorphisms, and methods of correcting taste defects are also provided. ...
08/05/2008
71695532-Azapurine compounds and their use
Within oligonucleotides 2-azapurine and especially 2-azaadenine bases form specifically base pairs with guanine. This base pair is of analogous stability as an adenine-thymine but less stable than a guanine-cytosine base pair. Therefore, the incorporation of 2-azaad...
01/30/2007
D527186Brush
08/29/2006
D514901Wine funnel
02/14/2006
6995017Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
A method for DNA reassembly after random fragmentation, and its application to mutagenesis of nucleic acid sequences by in vitro or in vivo recombination is described. In particular, a method for the production of nucleic acid fragments or polynucleotides encoding m...
02/07/2006
6928899Striking head-interchangeable hammer with a stress-distributable fastener
A striking head-interchangeable hammer includes a handle, a head body connected securely to the handle and formed with a through-hole and upper and lower bores, a striking body having a connecting portion that is received fittingly in the lower bore, and a stress-di...
08/16/2005
6901829Turret lathe with a clutch for operating between chamfering and turning operation modes
A turret lathe includes a bed, a headstock mounted on the bed, a first slide mounted slidably on the bed, a second slide mounted slidably on the first slide, a spindle journalled to the headstock, a chuck mounted on the spindle, a tailstock mounted on the second sli...
06/07/2005
6900182Inositolphosphoglycan and ribose for treatment of ischaemia-reperfusion injury
Compositions comprising inositolphosphoglycans (IPGs) and ribose are disclosed, and their use in the prevention or treatment of ischaemic-reperfusion injury. This treatment increases the energy generating systems of cells by employing the mitochondrial oxidative res...
05/31/2005
6851319Device and method designed for ultrasonically inspecting cylinders for longitudinal and circumferential defects and to measure wall thickness
Methods and apparatus for ultrasonically scanning cylinders are provided. The methods and apparatus employ as few as one ultrasonic sensor for full immersion scanning and defect detection. Self-centering fixturing spins the cylinder, reducing vibration, allowing for...
02/08/2005
6849411Microfluidic sequencing methods
Integrated systems, apparatus, software, and methods for performing biochemical analysis, including DNA sequencing, genomic screening, purification of nucleic acids and other biological components and drug screening are provided. Microfluidic devices, systems and me...
02/01/2005
6837828Elasticity-controllable trampoline using plate spring
Disclosed is an elasticity-controllable trampoline using a plate spring that can be manufactured in small size and in low height compared with existing trampolines using coil springs, thereby proving stability to a user. Also, it has a mechanical structure, thereby ...
01/04/2005
6799120Nonredundant split/pool synthesis of combinatorial libraries
The present invention includes methods for generating combinatorial libraries on solid phase supports in which increased productivity is achieved by pooling all common steps in synthesis without using a tracking or coding system to record the synthetic history of ea...
09/28/2004
6787088Controlled fluid transport in microfabricated polymeric substrates
Microfluidic devices are provided for the performance of chemical and biochemical analyzes, syntheses and detection. The devices of the invention combine precise fluidic control systems with microfabricated polymeric substrates to provide accurate, low cost miniatur...
09/07/2004
6758132Electric cooking device suitable for grilling and baking foodstuffs
A base unit of an electric cooking device includes a grill plate that has front and rear edge portions opposite to each other along a plate axis. An oil-collecting hole is formed adjacent to the front edge portion. The grill plate has a top cooking surface that incl...
07/06/2004
6756019Microfluidic devices and systems incorporating cover layers
The present invention provides microfluidic devices that comprise a body structure comprising at least a first microscale channel network disposed therein. The body structure has a plurality of ports disposed in the body structure, where each port is in fluid commun...
06/29/2004
6716631Evolution of whole cells and organisms by recursive sequence recombination
The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number...
04/06/2004
6703205Apparatus and methods for correcting for variable velocity in microfluidic systems
Electrokinetic devices having a computer for correcting for electrokinetic effects are provided. Methods of correcting for electrokinetic effects by establishing the velocity of reactants and products in a reaction in electrokinetic microfluidic devices a...
03/09/2004
6653072Methods and compositions for polypeptide engineering
Methods are provided for the evolution of proteins of industrial and pharmaceutical interest, including methods for effecting recombination and selection. Compositions produced by these methods are also disclosed....
11/25/2003
6635487Fluorescence standard for use in microfluidic instruments
A test device for use as a fluorescent standard in microfluidic analytical detection systems includes one or more slits that correspond to, and are of similar dimension to, one or more microchannels in a detection region on a corresponding analysis chip. ...
10/21/2003
6625546Structure identification methods using mass measurements
Methods of identifying predicted or actual structures of members of a chemical or physical library are provided. The methods provide for the direct identification of compound structure following combinatorial synthesis using molecular mass measurements of...
09/23/2003
6613512Apparatus and method for correcting for variable velocity in microfluidic systems
Electrokinetic devices having a computer for correcting for electrokinetic effects are provided. Methods of correcting for electrokinetic effects by establishing the velocity of reactants and products in a reaction in electrokinetic microfluidic devices a...
09/02/2003
6595061Noninvasive detection of corrosion, MIC, and foreign objects in containers using guided ultrasonic waves
Ultrasonic energy in the form of guided waves (plate waves or Lamb waves) is launched into the wall of a container. The guided wave propagates around the circumference of the container from a transmitting transducer to a receiving transducer. Analysis of ...
07/22/2003
6595059Noninvasive detection of corrosion, MIC, and foreign objects in fluid-filled pipes using leaky guided ultrasonic waves
Ultrasonic energy in the form of guided waves is launched into the wall of a fluid-filled container. The guided wave propagates around the circumference of the container from a transmitting transducer to a receiving transducer. Part of the guide wave ener...
07/22/2003
6582451Device for use in surgery
The instrument to manipulate the tissue of a body of a patient has jaws (15a, 15b) that move away from each other in a parallel motion. The artiuclating means for the jaws comprises a scissor type linkage (24a, 24b, 25a, 25b) constrained within a support ...
06/24/2003
6548254Methods and compositions for the manufacture of molecular beacons
Ligation-based assembly of oligonucleotides to produce molecular beacons is provided. Formation of molecular beacons is monitored to improve reaction yield and efficiency and to permit optimization of structurally similar molecular beacons. Ligation mixtu...
04/15/2003
6447727Microfluidic systems
The present invention generally provides microfluidic devices and systems that utilize electrokinetic material transport systems to selectively control and direct the transport of materials through and among complex arrangements of integrated, interconnec...
09/10/2002
6367328Noninvasive detection of corrosion, MIC, and foreign objects in fluid-filled containers using leaky guided ultrasonic waves
Ultrasonic energy in the form of guided waves is launched into the wall of a fluid-filled container. The guided wave propagates around the circumference of the container from a transmitting transducer to a receiving transducer. Part of the guide wave ener...
04/09/2002
6363788Noninvasive detection of corrosion, mic, and foreign objects in containers, using guided ultrasonic waves
Ultrasonic energy in the form of guided waves (plate waves or Lamb waves) is launched into the wall of a container. The guided wave propagates around the circumference of the container from a transmitting transducer to a receiving transducer. Analysis of ...
04/02/2002
 
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